𝕏

Task 55971051

Name HuVeMOp_20240703211544821569_ORdGradInc_k_26-Pueyo_APDR-conf_284_0
Workunit 26580506
Created 3 Jul 2024, 19:16:48 UTC
Sent 3 Jul 2024, 20:28:41 UTC
Report deadline 7 Jul 2024, 6:04:41 UTC
Received 4 Jul 2024, 4:52:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219753
Run time 1 hours 21 min 31 sec
CPU time 1 hours 20 min 32 sec
Validate state Valid
Credit 61.05
Device peak FLOPS 5.92 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.30 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Pueyo_APDR-conf_284.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r381939654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r381939654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.481587
     * GNaL_b in INaL: 0.005489
     * Gto_b in Ito: 0.082264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031458
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.165651
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.050106
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13399252, states[0] = -95.133923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26637233, states[0] = -61.318324, states[40]= 0.000004
Saving checkpoint... 
Iteration: 39428079, states[0] = -95.088554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52429352, states[0] = -95.076796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65769490, states[0] = -94.986085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79001370, states[0] = 48.277869, states[40]= 0.053036
Saving checkpoint... 
Iteration: 92100233, states[0] = -20.237255, states[40]= 0.000950
Saving checkpoint... 
Iteration: 105100670, states[0] = -20.513275, states[40]= 0.000932
Saving checkpoint... 
Iteration: 118106942, states[0] = -26.371372, states[40]= 0.000637
Saving checkpoint... 
Iteration: 131140851, states[0] = -61.252941, states[40]= 0.000004
Saving checkpoint... 
Iteration: 144408812, states[0] = -95.049149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157484013, states[0] = -95.063096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170693116, states[0] = -94.853034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183845563, states[0] = -95.024985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196859242, states[0] = -95.031031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210122157, states[0] = -40.884813, states[40]= 0.000112
Saving checkpoint... 
Iteration: 223139166, states[0] = -59.107639, states[40]= 0.000006
Saving checkpoint... 
Iteration: 236790767, states[0] = -94.989426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249550844, states[0] = 11.285425, states[40]= 0.004981
Saving checkpoint... 
Iteration: 262762519, states[0] = -94.962142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275942715, states[0] = -95.055285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289008587, states[0] = 23.989439, states[40]= 0.072719
Saving checkpoint... 
Iteration: 302304367, states[0] = -94.999862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315866371, states[0] = -95.033556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328301292, states[0] = -94.997572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341256516, states[0] = -94.955181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354171983, states[0] = -94.657461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367208610, states[0] = -94.882829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379623789, states[0] = -42.518062, states[40]= 0.000088
Saving checkpoint... 
Iteration: 393036131, states[0] = 16.768002, states[40]= 0.005505
Saving checkpoint... 
Iteration: 405834984, states[0] = -95.018947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418884553, states[0] = -95.040122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432094521, states[0] = -14.410102, states[40]= 0.001548
Saving checkpoint... 
Iteration: 445036639, states[0] = 16.592177, states[40]= 0.005470
Saving checkpoint... 
Iteration: 458068080, states[0] = 3.893044, states[40]= 0.004646
Saving checkpoint... 
Iteration: 471069862, states[0] = 3.021183, states[40]= 0.004576
Saving checkpoint... 
Iteration: 484020599, states[0] = 21.232837, states[40]= 0.009300
Saving checkpoint... 
Iteration: 497145765, states[0] = -67.131620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509983474, states[0] = -95.061724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523194971, states[0] = -94.855938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536220674, states[0] = -94.904137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549626164, states[0] = -44.959085, states[40]= 0.000061
Saving checkpoint... 
Iteration: 562847281, states[0] = -95.025073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575973103, states[0] = -95.060230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589280165, states[0] = -94.979792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602467833, states[0] = -95.059420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615745925, states[0] = -94.941812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628321714, states[0] = -95.011204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641469060, states[0] = -95.059584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654603406, states[0] = -22.807547, states[40]= 0.000805
Saving checkpoint... 
Iteration: 667429026, states[0] = -95.052161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680564637, states[0] = 5.501948, states[40]= 0.004751
Saving checkpoint... 
Iteration: 693949379, states[0] = -95.056253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706917533, states[0] = -95.049451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720106240, states[0] = -25.494143, states[40]= 0.000679
Saving checkpoint... 
Iteration: 733333102, states[0] = -95.017723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746139055, states[0] = -58.966593, states[40]= 0.000006
Saving checkpoint... 
Iteration: 759341635, states[0] = -95.022185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772747467, states[0] = -94.943724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785804034, states[0] = -94.999304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799065230, states[0] = 5.231230, states[40]= 0.004735
Saving checkpoint... 
Iteration: 811974896, states[0] = -95.060345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824950908, states[0] = -95.056450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838264627, states[0] = -94.964046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850930028, states[0] = -95.052268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863854248, states[0] = -95.028099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876582263, states[0] = -4.220340, states[40]= 0.003547
Saving checkpoint... 
Iteration: 889673425, states[0] = -94.715627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902920657, states[0] = -95.050088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916026888, states[0] = 19.676786, states[40]= 0.006684
Saving checkpoint... 
Iteration: 928812367, states[0] = -95.005035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941697783, states[0] = -94.861423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954791072, states[0] = -94.989124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967853001, states[0] = -95.027475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980948152, states[0] = -95.055848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994029424, states[0] = 18.942315, states[40]= 0.006216
Saving checkpoint... 
Iteration: 1007187885, states[0] = -94.840148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020385983, states[0] = -95.040224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033407262, states[0] = -95.046593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046812942, states[0] = -95.005346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059853160, states[0] = -95.027489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072989941, states[0] = -95.062211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085980439, states[0] = -95.060956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098795457, states[0] = -94.992591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111781132, states[0] = -94.980358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124359869, states[0] = -95.030378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137689816, states[0] = -94.844524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150778870, states[0] = -94.978235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163925097, states[0] = -95.050967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176828213, states[0] = -95.014710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189440042, states[0] = -95.054157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202651641, states[0] = -75.755115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215427407, states[0] = -95.051460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228854820, states[0] = -95.028127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242071721, states[0] = 2.078021, states[40]= 0.004489
Saving checkpoint... 
Iteration: 1255214750, states[0] = -94.893448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268401868, states[0] = -95.044949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281300315, states[0] = -94.996238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294453316, states[0] = -95.056589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307466073, states[0] = -95.058708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320674227, states[0] = -94.738516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333165888, states[0] = -93.773754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346030391, states[0] = 18.648256, states[40]= 0.006076
Saving checkpoint... 
Iteration: 1358754781, states[0] = -94.952477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371981125, states[0] = -95.060873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385151149, states[0] = -74.955839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398534268, states[0] = 17.401095, states[40]= 0.005652
Saving checkpoint... 
Iteration: 1411723835, states[0] = -94.908832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425145099, states[0] = -66.260876, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1438356718, states[0] = -95.028831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451536875, states[0] = 16.510237, states[40]= 0.005454
Saving checkpoint... 
Iteration: 1464422946, states[0] = -95.050281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477676957, states[0] = -94.787028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490989377, states[0] = -95.061881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504159083, states[0] = -95.251671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517496514, states[0] = -31.886728, states[40]= 0.000369
Saving checkpoint... 
Iteration: 1530616752, states[0] = 22.184418, states[40]= 0.015836
Saving checkpoint... 
Iteration: 1543497818, states[0] = -95.317435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556713834, states[0] = 22.875431, states[40]= 0.024603
Saving checkpoint... 
Iteration: 1569656707, states[0] = 3.825944, states[40]= 0.005257
Saving checkpoint... 
Iteration: 1583272855, states[0] = -95.162425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596734716, states[0] = -86.081407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610186660, states[0] = -23.325849, states[40]= 0.000804
Saving checkpoint... 
Iteration: 1623754280, states[0] = -95.094674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636987379, states[0] = -95.199574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649978904, states[0] = -95.321530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662828952, states[0] = -95.270492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675744871, states[0] = -95.290071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689147538, states[0] = -94.893518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702594428, states[0] = -31.940060, states[40]= 0.000370
Saving checkpoint... 
Iteration: 1715419069, states[0] = 21.248480, states[40]= 0.012089
Saving checkpoint... 
Iteration: 1728625927, states[0] = 18.861170, states[40]= 0.008007
Saving checkpoint... 
Iteration: 1742002877, states[0] = -95.230429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755406977, states[0] = -46.103774, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1768128843, states[0] = -95.270633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781249569, states[0] = -95.000244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794747089, states[0] = -94.860300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808021006, states[0] = 20.671047, states[40]= 0.008564
Saving checkpoint... 
Iteration: 1820840273, states[0] = -95.056757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834078410, states[0] = -2.566852, states[40]= 0.003881
Saving checkpoint... 
Iteration: 1847223404, states[0] = -94.925056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860812436, states[0] = -95.015814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874309508, states[0] = -95.010085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887729628, states[0] = -94.922926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900799614, states[0] = -94.998774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914221715, states[0] = -94.907373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927517000, states[0] = 21.927580, states[40]= 0.013643
Saving checkpoint... 
Iteration: 1940641387, states[0] = -61.774383, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1954113584, states[0] = -32.537537, states[40]= 0.000350
Saving checkpoint... 
Iteration: 1967001078, states[0] = 48.131351, states[40]= 0.032642
Saving checkpoint... 
Iteration: 1980163488, states[0] = -92.721351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993267239, states[0] = -94.966305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005702202, states[0] = -94.869658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018910990, states[0] = -95.047031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032057568, states[0] = 8.568217, states[40]= 0.004887
Saving checkpoint... 
Iteration: 2044890780, states[0] = -95.041136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058291599, states[0] = -94.988854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071128014, states[0] = -46.894565, states[40]= 0.000045
Saving checkpoint... 
Iteration: 2084471786, states[0] = -95.059062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097896597, states[0] = -95.042851, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.938610
 - CaMKt in component CaMK (millimolar): 0.006906
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.536027
 - nass in component intracellular_ions (millimolar): 6.536087
 - ki in component intracellular_ions (millimolar): 145.442690
 - kss in component intracellular_ions (millimolar): 145.442670
 - cansr in component intracellular_ions (millimolar): 1.307378
 - cajsr in component intracellular_ions (millimolar): 1.269477
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003605
 - hf in component INa (dimensionless): 0.880637
 - hs in component INa (dimensionless): 0.880633
 - j in component INa (dimensionless): 0.880604
 - hsp in component INa (dimensionless): 0.727031
 - jp in component INa (dimensionless): 0.880585
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710950
 - hLp in component INaL (dimensionless): 0.453289
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621679
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696640
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935212
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330179
 - xs1 in component IKs (dimensionless): 0.241314
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:49:01 (41482): called boinc_finish(0)

</stderr_txt>
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