𝕏

Task 55970227

Name HuVeMOp_20240703211544821569_ORdGradInc_k_26-Drouin_ENDO_1000-conf_275_0
Workunit 26580094
Created 3 Jul 2024, 19:16:18 UTC
Sent 3 Jul 2024, 20:21:18 UTC
Report deadline 6 Jul 2024, 20:21:18 UTC
Received 5 Jul 2024, 2:11:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 54 min 44 sec
CPU time 1 hours 28 min 15 sec
Validate state Valid
Credit 43.49
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Drouin_ENDO_1000-conf_275.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Drouin_ENDO_1000-conf_275_0_r1184017620_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Drouin_ENDO_1000-conf_275_0_r1184017620_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.305323
     * GNaL_b in INaL: 0.005656
     * Gto_b in Ito: 0.083403
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031816
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162865
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.461837
     * GKb_b in IKb: 0.003826
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029126
     * celltype in environment: 0.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8373325, states[0] = -94.342899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17331448, states[0] = -94.243208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25876179, states[0] = -94.287682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34965198, states[0] = -94.345705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42782783, states[0] = -94.133672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51568867, states[0] = 13.900843, states[40]= 0.001247
Saving checkpoint... 
Iteration: 59676059, states[0] = -78.427936, states[40]= 0.000002
Saving checkpoint... 
Iteration: 67526663, states[0] = 30.599852, states[40]= 0.000265
Saving checkpoint... 
Iteration: 75901129, states[0] = -94.331080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85275370, states[0] = -94.129173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93894937, states[0] = -94.330138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102293167, states[0] = -94.180824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110823960, states[0] = -94.246113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119193045, states[0] = -93.401740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127771058, states[0] = -94.120609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135898152, states[0] = -94.336181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143707228, states[0] = -93.826117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152439811, states[0] = -94.362448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160794132, states[0] = -94.186123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169549141, states[0] = 22.246572, states[40]= 0.000345
Saving checkpoint... 
Iteration: 178752015, states[0] = -94.053924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186943963, states[0] = -94.364640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196296782, states[0] = -94.192598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204576742, states[0] = 9.847373, states[40]= 0.001777
Saving checkpoint... 
Iteration: 213504521, states[0] = 34.789112, states[40]= 0.410487
Saving checkpoint... 
Iteration: 222528559, states[0] = 29.950197, states[40]= 0.000181
Saving checkpoint... 
Iteration: 231603248, states[0] = -7.157683, states[40]= 0.002815
Saving checkpoint... 
Iteration: 239235005, states[0] = -93.980010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247912369, states[0] = -94.346615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255903733, states[0] = -94.340546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265643695, states[0] = -44.968228, states[40]= 0.000360
Saving checkpoint... 
Iteration: 274827316, states[0] = -94.253357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282710503, states[0] = -93.848348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291001658, states[0] = 48.580768, states[40]= 0.702177
Saving checkpoint... 
Iteration: 300494949, states[0] = -94.381689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308086882, states[0] = 4.485716, states[40]= 0.002700
Saving checkpoint... 
Iteration: 315911117, states[0] = -94.345124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323956194, states[0] = -94.368845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331901005, states[0] = -94.337785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340156589, states[0] = -57.318005, states[40]= 0.000063
Saving checkpoint... 
Iteration: 349079880, states[0] = 8.265375, states[40]= 0.002055
Saving checkpoint... 
Iteration: 358465815, states[0] = -94.372186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366245095, states[0] = -94.024005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374222101, states[0] = -93.913814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382191651, states[0] = -93.250858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389904377, states[0] = -94.339678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398097182, states[0] = -2.181893, states[40]= 0.003239
Saving checkpoint... 
Iteration: 406763209, states[0] = -94.093468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415387229, states[0] = -94.325786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423539552, states[0] = 26.089213, states[40]= 0.000181
Saving checkpoint... 
Iteration: 431630502, states[0] = -32.806569, states[40]= 0.001274
Saving checkpoint... 
Iteration: 441060681, states[0] = 17.302618, states[40]= 0.000727
Saving checkpoint... 
Iteration: 449116810, states[0] = -20.219514, states[40]= 0.001410
Saving checkpoint... 
Iteration: 457409461, states[0] = -94.342564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466794970, states[0] = -94.185680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475170208, states[0] = -71.900735, states[40]= 0.000006
Saving checkpoint... 
Iteration: 484109192, states[0] = -12.783500, states[40]= 0.001948
Saving checkpoint... 
Iteration: 492801626, states[0] = -94.200966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501285131, states[0] = -94.160067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511226165, states[0] = -93.933660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518903416, states[0] = -94.337664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527796647, states[0] = -94.189083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535754359, states[0] = -94.059735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544244848, states[0] = -94.021106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552980301, states[0] = -94.375033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561771064, states[0] = -94.118037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570239008, states[0] = -93.995148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579449678, states[0] = -94.363505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587423927, states[0] = -94.350379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596740035, states[0] = -93.999504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604937244, states[0] = -94.357415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613168218, states[0] = -69.476282, states[40]= 0.000009
Saving checkpoint... 
Iteration: 622379363, states[0] = -94.316511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630911988, states[0] = -94.342498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638719866, states[0] = -93.899009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646690312, states[0] = -93.019856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655923111, states[0] = -94.349203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663973462, states[0] = -94.371728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673349413, states[0] = -94.282315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681653630, states[0] = -54.450725, states[40]= 0.000097
Saving checkpoint... 
Iteration: 691139651, states[0] = -41.177150, states[40]= 0.000571
Saving checkpoint... 
Iteration: 699808502, states[0] = -94.213721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707958249, states[0] = -94.365761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716320580, states[0] = -94.237058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724699708, states[0] = -93.732702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733779667, states[0] = -94.142371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742594669, states[0] = -0.377227, states[40]= 0.003214
Saving checkpoint... 
Iteration: 751413512, states[0] = -94.342274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760693380, states[0] = -93.443135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769275799, states[0] = -94.130581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777253969, states[0] = -94.055730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785469007, states[0] = -94.368975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794335908, states[0] = -94.261861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804396091, states[0] = -94.329180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812630301, states[0] = -32.619523, states[40]= 0.001290
Saving checkpoint... 
Iteration: 820520407, states[0] = 31.974747, states[40]= 0.001694
Saving checkpoint... 
Iteration: 829954141, states[0] = -94.362853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838947243, states[0] = -94.359783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847325061, states[0] = -94.243658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856560247, states[0] = 17.495304, states[40]= 0.000708
Saving checkpoint... 
Iteration: 865283342, states[0] = -94.151412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874240136, states[0] = -93.997074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884722192, states[0] = -93.908975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893039784, states[0] = 26.001425, states[40]= 0.000184
Saving checkpoint... 
Iteration: 901422862, states[0] = -94.346554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909384619, states[0] = -94.318434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918208668, states[0] = -93.829538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926742836, states[0] = -94.008462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934540214, states[0] = 25.835509, states[40]= 0.000189
Saving checkpoint... 
Iteration: 942607967, states[0] = -11.581765, states[40]= 0.002126
Saving checkpoint... 
Iteration: 951736538, states[0] = -93.979839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960701328, states[0] = -93.758291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969428409, states[0] = -94.349034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977973363, states[0] = -94.368498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987200401, states[0] = -93.742929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996696392, states[0] = -93.631173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007004494, states[0] = 34.857514, states[40]= 0.414206
Saving checkpoint... 
Iteration: 1014995242, states[0] = -94.374500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023134383, states[0] = -36.329099, states[40]= 0.000954
Saving checkpoint... 
Iteration: 1031673209, states[0] = -75.844847, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1040760741, states[0] = -94.078195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049726728, states[0] = -93.930933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057899274, states[0] = -94.329070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066634126, states[0] = -36.094162, states[40]= 0.000975
Saving checkpoint... 
Iteration: 1074962485, states[0] = -94.363660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083141104, states[0] = -42.524877, states[40]= 0.000487
Saving checkpoint... 
Iteration: 1091546240, states[0] = 23.437825, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1101353393, states[0] = -94.283075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110231786, states[0] = -93.955559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119276714, states[0] = -94.129719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127900314, states[0] = -94.329146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137178298, states[0] = -83.247468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146892548, states[0] = -94.322825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156485396, states[0] = -94.370398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164866134, states[0] = -94.297443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174573347, states[0] = 11.501241, states[40]= 0.001499
Saving checkpoint... 
Iteration: 1181920234, states[0] = -94.342122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190495385, states[0] = -94.372750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198428021, states[0] = -94.346485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206011521, states[0] = 32.225950, states[40]= 0.036291
Saving checkpoint... 
Iteration: 1214547296, states[0] = 23.006362, states[40]= 0.000305
Saving checkpoint... 
Iteration: 1223263451, states[0] = -94.085867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230953650, states[0] = -94.358565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238499574, states[0] = -94.373296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247248969, states[0] = -94.031007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257116146, states[0] = -19.574601, states[40]= 0.001411
Saving checkpoint... 
Iteration: 1267683386, states[0] = -89.542079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277632206, states[0] = -34.343882, states[40]= 0.001136
Saving checkpoint... 
Iteration: 1287284698, states[0] = -94.150792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296118179, states[0] = -21.507884, states[40]= 0.001431
Saving checkpoint... 
Iteration: 1303922780, states[0] = -94.342403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313129798, states[0] = -32.157026, states[40]= 0.001329
Saving checkpoint... 
Iteration: 1322485270, states[0] = -94.368672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331339991, states[0] = -94.262478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339969033, states[0] = -94.363338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349592492, states[0] = 1.083960, states[40]= 0.003122
Saving checkpoint... 
Iteration: 1358303844, states[0] = -94.197000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367094832, states[0] = -0.485059, states[40]= 0.003219
Saving checkpoint... 
Iteration: 1375876381, states[0] = -94.305935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384222076, states[0] = -93.903145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392708478, states[0] = -93.823235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401887434, states[0] = -94.315894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410307390, states[0] = -94.204094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419517309, states[0] = 32.379860, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1428081588, states[0] = 7.385564, states[40]= 0.002213
Saving checkpoint... 
Iteration: 1436603151, states[0] = -7.060859, states[40]= 0.002830
Saving checkpoint... 
Iteration: 1445811915, states[0] = -94.213032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454583624, states[0] = 6.302151, states[40]= 0.002403
Saving checkpoint... 
Iteration: 1462899935, states[0] = -94.325441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471880537, states[0] = -94.308945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481737032, states[0] = -93.976621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489560510, states[0] = 17.381905, states[40]= 0.000720
Saving checkpoint... 
Iteration: 1497902228, states[0] = -94.326803, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.246613
 - CaMKt in component CaMK (millimolar): 0.017872
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 7.069862
 - nass in component intracellular_ions (millimolar): 7.069986
 - ki in component intracellular_ions (millimolar): 144.706687
 - kss in component intracellular_ions (millimolar): 144.706667
 - cansr in component intracellular_ions (millimolar): 1.952603
 - cajsr in component intracellular_ions (millimolar): 1.908606
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003866
 - hf in component INa (dimensionless): 0.868159
 - hs in component INa (dimensionless): 0.868148
 - j in component INa (dimensionless): 0.868079
 - hsp in component INa (dimensionless): 0.703860
 - jp in component INa (dimensionless): 0.868030
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.686126
 - hLp in component INaL (dimensionless): 0.416255
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.595915
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.661994
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.900393
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999759
 - jca in component ICaL (dimensionless): 0.999965
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004658
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.398844
 - xs1 in component IKs (dimensionless): 0.290982
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997504
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:10:41 (80386): called boinc_finish(0)

</stderr_txt>
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