𝕏

Task 55970226

Name HuVeMOp_20240703211544821569_ORdGradInc_k_26-Coppini_2000-conf_975_1
Workunit 26580093
Created 3 Jul 2024, 19:16:18 UTC
Sent 3 Jul 2024, 20:21:18 UTC
Report deadline 6 Jul 2024, 20:21:18 UTC
Received 5 Jul 2024, 2:11:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 59 min 11 sec
CPU time 1 hours 28 min 17 sec
Validate state Valid
Credit 43.27
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.66 MB
Peak swap size 4.00 MB
Peak disk usage 0.65 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Coppini_2000-conf_975.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Coppini_2000-conf_975_1_r160122057_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-Coppini_2000-conf_975_1_r160122057_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.292012
     * GNaL_b in INaL: 0.005945
     * Gto_b in Ito: 0.082484
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031344
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.160865
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.640467
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033627
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8022638, states[0] = 25.755269, states[40]= 0.003649
Saving checkpoint... 
Iteration: 16244783, states[0] = -94.424143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24330388, states[0] = -94.553357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33718851, states[0] = -94.667333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42397638, states[0] = -94.582261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50452731, states[0] = -94.605742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58181236, states[0] = -78.257447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66340583, states[0] = -94.508332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75232327, states[0] = -94.255751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83812829, states[0] = -94.631484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92050606, states[0] = 19.618768, states[40]= 0.002613
Saving checkpoint... 
Iteration: 99993400, states[0] = -94.624159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107451294, states[0] = -94.584532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115145539, states[0] = -40.070984, states[40]= 0.000409
Saving checkpoint... 
Iteration: 123333944, states[0] = -94.486789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132676296, states[0] = -94.622889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141192657, states[0] = -91.144720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150228775, states[0] = -94.231517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158074699, states[0] = 10.882607, states[40]= 0.004155
Saving checkpoint... 
Iteration: 167039172, states[0] = 23.134671, states[40]= 0.001984
Saving checkpoint... 
Iteration: 176457780, states[0] = -94.582907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185549877, states[0] = -94.608649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193790272, states[0] = -94.622217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202537837, states[0] = -94.606139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210170724, states[0] = -63.343880, states[40]= 0.000011
Saving checkpoint... 
Iteration: 216971676, states[0] = -94.618487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225967212, states[0] = -94.618528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233838112, states[0] = -94.621294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242240676, states[0] = -94.272319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250551441, states[0] = -94.608269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257977474, states[0] = -94.618068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265721943, states[0] = -94.621338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274346661, states[0] = -94.499529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282290750, states[0] = -94.409182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291353352, states[0] = -94.507286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299587826, states[0] = -94.613358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307965098, states[0] = -94.618232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316649118, states[0] = -94.618607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325981982, states[0] = -94.617741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335614452, states[0] = -94.616031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343055285, states[0] = 18.202233, states[40]= 0.002947
Saving checkpoint... 
Iteration: 351686026, states[0] = -94.620215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360462383, states[0] = -94.583642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368070969, states[0] = 12.451907, states[40]= 0.003961
Saving checkpoint... 
Iteration: 376132629, states[0] = -28.906252, states[40]= 0.001277
Saving checkpoint... 
Iteration: 385066513, states[0] = 14.200763, states[40]= 0.003696
Saving checkpoint... 
Iteration: 393272943, states[0] = -94.367650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401560349, states[0] = -94.609347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410778432, states[0] = -94.621340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419511818, states[0] = -94.599481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428305499, states[0] = -94.437822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436452070, states[0] = -94.579134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445653368, states[0] = -94.618589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453975498, states[0] = -94.617660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462184025, states[0] = -79.965816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470817040, states[0] = -94.620949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478665570, states[0] = -94.619148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487092451, states[0] = 2.307704, states[40]= 0.004530
Saving checkpoint... 
Iteration: 495323573, states[0] = -94.467765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503658790, states[0] = -94.618769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511544943, states[0] = -94.606506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519816547, states[0] = -94.620863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527857630, states[0] = -94.620245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536127335, states[0] = -24.527434, states[40]= 0.001424
Saving checkpoint... 
Iteration: 544123533, states[0] = -21.361633, states[40]= 0.001384
Saving checkpoint... 
Iteration: 553003365, states[0] = 35.145918, states[40]= 0.401458
Saving checkpoint... 
Iteration: 561571207, states[0] = -94.610674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569520741, states[0] = -94.601370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577750209, states[0] = -94.620988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586695604, states[0] = -94.620072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595010209, states[0] = 27.022901, states[40]= 0.044807
Saving checkpoint... 
Iteration: 603918915, states[0] = -94.618814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612165532, states[0] = -58.162642, states[40]= 0.000026
Saving checkpoint... 
Iteration: 620946223, states[0] = -94.618111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629165581, states[0] = -58.209792, states[40]= 0.000026
Saving checkpoint... 
Iteration: 637297089, states[0] = -94.421446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646011711, states[0] = 27.094691, states[40]= 0.027407
Saving checkpoint... 
Iteration: 654705841, states[0] = -94.620214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662588557, states[0] = -94.612738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670967301, states[0] = -94.617473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679141710, states[0] = -36.521129, states[40]= 0.000639
Saving checkpoint... 
Iteration: 687814922, states[0] = -94.620568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696642565, states[0] = -94.617480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703976474, states[0] = -94.617169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712535716, states[0] = -94.604352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721199608, states[0] = -93.640759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730011479, states[0] = 27.081402, states[40]= 0.029551
Saving checkpoint... 
Iteration: 738104513, states[0] = -5.468840, states[40]= 0.003516
Saving checkpoint... 
Iteration: 745742024, states[0] = -94.620617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754264120, states[0] = -94.343614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763225183, states[0] = -94.215106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771457195, states[0] = -94.580728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780245736, states[0] = -94.288081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788237766, states[0] = -94.261088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796513555, states[0] = -94.599215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805684900, states[0] = -94.619324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813671501, states[0] = -94.618791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823590892, states[0] = -94.612711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832513028, states[0] = -94.599016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840235213, states[0] = -94.251989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848095499, states[0] = 0.546727, states[40]= 0.004424
Saving checkpoint... 
Iteration: 856311601, states[0] = -94.447789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864668864, states[0] = -94.618580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873082466, states[0] = 7.431061, states[40]= 0.004463
Saving checkpoint... 
Iteration: 881873068, states[0] = -94.619298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890176297, states[0] = -69.449143, states[40]= 0.000004
Saving checkpoint... 
Iteration: 898089670, states[0] = 3.824266, states[40]= 0.004564
Saving checkpoint... 
Iteration: 905581643, states[0] = -94.611437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913986639, states[0] = -94.616505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922720390, states[0] = -94.620012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931110439, states[0] = -10.169910, states[40]= 0.002492
Saving checkpoint... 
Iteration: 939161945, states[0] = -54.749213, states[40]= 0.000046
Saving checkpoint... 
Iteration: 948738608, states[0] = -94.620207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957104508, states[0] = -5.464804, states[40]= 0.003517
Saving checkpoint... 
Iteration: 965756187, states[0] = -94.620295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973784402, states[0] = -94.620271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982157950, states[0] = -51.014228, states[40]= 0.000084
Saving checkpoint... 
Iteration: 990477577, states[0] = -94.588171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998394032, states[0] = -94.543919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007637914, states[0] = -94.616596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016081089, states[0] = 8.076040, states[40]= 0.004421
Saving checkpoint... 
Iteration: 1024319126, states[0] = -94.459875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033317718, states[0] = -94.457608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041263520, states[0] = -94.341410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049758512, states[0] = -94.620147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058109894, states[0] = -9.716681, states[40]= 0.002588
Saving checkpoint... 
Iteration: 1065966044, states[0] = -94.616771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074087051, states[0] = 5.184626, states[40]= 0.004554
Saving checkpoint... 
Iteration: 1082144530, states[0] = -38.939844, states[40]= 0.000474
Saving checkpoint... 
Iteration: 1090386465, states[0] = -94.537754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099518171, states[0] = -94.599777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108709430, states[0] = -94.619452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116345088, states[0] = -94.495979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125332563, states[0] = -94.479628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133823702, states[0] = -94.619636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143068563, states[0] = 13.408973, states[40]= 0.003821
Saving checkpoint... 
Iteration: 1151833423, states[0] = -94.619472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159849370, states[0] = -94.619211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168185620, states[0] = -82.395693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176018567, states[0] = 27.152606, states[40]= 0.003874
Saving checkpoint... 
Iteration: 1184485581, states[0] = -94.590507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193100649, states[0] = -2.722790, states[40]= 0.004028
Saving checkpoint... 
Iteration: 1202241882, states[0] = -94.274452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212129609, states[0] = -26.406142, states[40]= 0.001401
Saving checkpoint... 
Iteration: 1220772911, states[0] = -94.619842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228527526, states[0] = -94.601673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237093655, states[0] = 1.626168, states[40]= 0.004498
Saving checkpoint... 
Iteration: 1247095121, states[0] = 0.771887, states[40]= 0.004442
Saving checkpoint... 
Iteration: 1255840736, states[0] = -94.619171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263564434, states[0] = -94.608374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271517479, states[0] = -94.599291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279385198, states[0] = -94.536355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287444127, states[0] = -94.573891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296026293, states[0] = 26.191609, states[40]= 0.001694
Saving checkpoint... 
Iteration: 1305081962, states[0] = 7.668954, states[40]= 0.004448
Saving checkpoint... 
Iteration: 1314865543, states[0] = -94.618637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323682615, states[0] = -94.618280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332563790, states[0] = -94.608148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340484457, states[0] = -94.589850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347807459, states[0] = -94.619417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355731943, states[0] = -94.619376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362929805, states[0] = -94.617139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371110281, states[0] = -10.037521, states[40]= 0.002520
Saving checkpoint... 
Iteration: 1379407224, states[0] = -94.552681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387610850, states[0] = -94.613734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396128017, states[0] = -25.090148, states[40]= 0.001423
Saving checkpoint... 
Iteration: 1404423330, states[0] = -94.562714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413225275, states[0] = -94.214226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422004309, states[0] = 31.489130, states[40]= 0.309831
Saving checkpoint... 
Iteration: 1430498959, states[0] = -94.594130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439020247, states[0] = 27.026011, states[40]= 0.002800
Saving checkpoint... 
Iteration: 1447246487, states[0] = -94.289271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455917708, states[0] = -94.617257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464887715, states[0] = -94.617915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474098885, states[0] = -1.555805, states[40]= 0.004199
Saving checkpoint... 
Iteration: 1483413389, states[0] = -94.556526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492828392, states[0] = -94.618907, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.490990
 - CaMKt in component CaMK (millimolar): 0.004217
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.507563
 - nass in component intracellular_ions (millimolar): 6.507649
 - ki in component intracellular_ions (millimolar): 145.404579
 - kss in component intracellular_ions (millimolar): 145.404565
 - cansr in component intracellular_ions (millimolar): 1.589863
 - cajsr in component intracellular_ions (millimolar): 1.589167
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003772
 - hf in component INa (dimensionless): 0.872686
 - hs in component INa (dimensionless): 0.872687
 - j in component INa (dimensionless): 0.872693
 - hsp in component INa (dimensionless): 0.712225
 - jp in component INa (dimensionless): 0.872696
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.718049
 - hLp in component INaL (dimensionless): 0.509424
 - a in component Ito (dimensionless): 0.000641
 - iF in component Ito (dimensionless): 0.999860
 - iS in component Ito (dimensionless): 0.891064
 - ap in component Ito (dimensionless): 0.000327
 - iFp in component Ito (dimensionless): 0.999860
 - iSp in component Ito (dimensionless): 0.930907
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975100
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002706
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.099053
 - xs1 in component IKs (dimensionless): 0.126549
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997443
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:03:48 (80660): called boinc_finish(0)

</stderr_txt>
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