𝕏

Task 55970104

Name HuVeMOp_20240703211544821569_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_272_1
Workunit 26580032
Created 3 Jul 2024, 19:16:17 UTC
Sent 3 Jul 2024, 20:18:43 UTC
Report deadline 6 Jul 2024, 23:11:31 UTC
Received 4 Jul 2024, 17:57:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239498
Run time 2 hours 22 min 50 sec
CPU time 2 hours 22 min 2 sec
Validate state Valid
Credit 51.03
Device peak FLOPS 2.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.24 MB
Peak swap size 6.33 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_272.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_272_1_r2119221107_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703211544821569_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_272_1_r2119221107_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 106.437609
     * GNaL_b in INaL: 0.005968
     * Gto_b in Ito: 0.086686
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026904
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.167118
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.300723
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037152
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10435641, states[0] = -95.002344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19891298, states[0] = -94.941281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29398224, states[0] = -94.926599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39010915, states[0] = 28.010395, states[40]= 0.036228
Saving checkpoint... 
Iteration: 48486023, states[0] = -94.944818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57994096, states[0] = -94.943252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67545810, states[0] = 20.335703, states[40]= 0.002648
Saving checkpoint... 
Iteration: 77064365, states[0] = 13.339482, states[40]= 0.004090
Saving checkpoint... 
Iteration: 86584930, states[0] = 3.656197, states[40]= 0.004941
Saving checkpoint... 
Iteration: 96096189, states[0] = -3.287653, states[40]= 0.004252
Saving checkpoint... 
Iteration: 105525105, states[0] = 26.745839, states[40]= 0.001849
Saving checkpoint... 
Iteration: 115010033, states[0] = 28.109433, states[40]= 0.048416
Saving checkpoint... 
Iteration: 124579429, states[0] = 6.595383, states[40]= 0.004886
Saving checkpoint... 
Iteration: 134053079, states[0] = 17.797107, states[40]= 0.003229
Saving checkpoint... 
Iteration: 143547703, states[0] = 19.747121, states[40]= 0.002813
Saving checkpoint... 
Iteration: 153069993, states[0] = 11.026163, states[40]= 0.004474
Saving checkpoint... 
Iteration: 162481459, states[0] = -94.931440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171954552, states[0] = -94.923804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181469273, states[0] = -94.928056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190941437, states[0] = -94.919124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200490751, states[0] = -94.933169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210031735, states[0] = 25.029251, states[40]= 0.001872
Saving checkpoint... 
Iteration: 219537531, states[0] = 23.231610, states[40]= 0.002144
Saving checkpoint... 
Iteration: 229009117, states[0] = 28.167753, states[40]= 0.065530
Saving checkpoint... 
Iteration: 238583095, states[0] = 4.735948, states[40]= 0.004949
Saving checkpoint... 
Iteration: 247988945, states[0] = -94.932494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257426402, states[0] = -94.912803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267008632, states[0] = 28.228017, states[40]= 0.076975
Saving checkpoint... 
Iteration: 276448230, states[0] = -94.921042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285910747, states[0] = -94.905478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295380382, states[0] = -94.887748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304832925, states[0] = -94.846274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314330814, states[0] = -94.843875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323819003, states[0] = -94.829601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333340754, states[0] = -94.854482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342856203, states[0] = -94.868990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352413974, states[0] = -94.906804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361823096, states[0] = -94.834596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371406935, states[0] = -94.903219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380907939, states[0] = -94.903701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390351263, states[0] = -94.864415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399910539, states[0] = -94.904945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409433991, states[0] = -94.915323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419024377, states[0] = 26.927787, states[40]= 0.001915
Saving checkpoint... 
Iteration: 428510980, states[0] = 28.121278, states[40]= 0.035449
Saving checkpoint... 
Iteration: 438039508, states[0] = 22.582238, states[40]= 0.002259
Saving checkpoint... 
Iteration: 447567955, states[0] = 11.920006, states[40]= 0.004350
Saving checkpoint... 
Iteration: 457038227, states[0] = 23.005515, states[40]= 0.002184
Saving checkpoint... 
Iteration: 466625918, states[0] = -27.585463, states[40]= 0.001483
Saving checkpoint... 
Iteration: 476132208, states[0] = -32.739383, states[40]= 0.001057
Saving checkpoint... 
Iteration: 485576919, states[0] = 7.854102, states[40]= 0.004810
Saving checkpoint... 
Iteration: 495111717, states[0] = -15.758370, states[40]= 0.001734
Saving checkpoint... 
Iteration: 504538779, states[0] = 22.823937, states[40]= 0.002215
Saving checkpoint... 
Iteration: 514020785, states[0] = 27.600939, states[40]= 0.002665
Saving checkpoint... 
Iteration: 523494366, states[0] = -94.932626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532981682, states[0] = -94.929728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542445733, states[0] = -94.919189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551943411, states[0] = -94.918333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561478544, states[0] = -94.928853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571065773, states[0] = 12.842570, states[40]= 0.004205
Saving checkpoint... 
Iteration: 573338708, states[0] = -94.851486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580118475, states[0] = -21.484901, states[40]= 0.001515
Saving checkpoint... 
Iteration: 589761830, states[0] = -94.727035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599442461, states[0] = -94.917818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609061859, states[0] = 14.442484, states[40]= 0.003923
Saving checkpoint... 
Iteration: 618684605, states[0] = -90.132864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628303916, states[0] = -94.807466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637920756, states[0] = -94.908910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647576563, states[0] = 8.025359, states[40]= 0.004797
Saving checkpoint... 
Iteration: 657232393, states[0] = -94.644152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666973742, states[0] = -94.927238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676654610, states[0] = -52.513597, states[40]= 0.000077
Saving checkpoint... 
Iteration: 686309131, states[0] = -94.814902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695988312, states[0] = -94.930674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705670307, states[0] = -69.033190, states[40]= 0.000005
Saving checkpoint... 
Iteration: 715337357, states[0] = -94.849546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724996993, states[0] = -94.932433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734632756, states[0] = -33.191204, states[40]= 0.001013
Saving checkpoint... 
Iteration: 744320122, states[0] = -94.829472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753985068, states[0] = -94.929718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763691317, states[0] = -93.826179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773329188, states[0] = -94.840321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783029527, states[0] = 25.656869, states[40]= 0.001810
Saving checkpoint... 
Iteration: 792701478, states[0] = -94.500750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802376253, states[0] = -94.883018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812087215, states[0] = 2.473827, states[40]= 0.004918
Saving checkpoint... 
Iteration: 821689476, states[0] = -93.333452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831386539, states[0] = -94.889809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840994176, states[0] = -94.931420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850670171, states[0] = -68.861163, states[40]= 0.000005
Saving checkpoint... 
Iteration: 860280121, states[0] = -94.765638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869936710, states[0] = -94.914685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879618627, states[0] = -21.610199, states[40]= 0.001516
Saving checkpoint... 
Iteration: 889255248, states[0] = -94.709621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899001373, states[0] = 48.685822, states[40]= 0.274251
Saving checkpoint... 
Iteration: 908709465, states[0] = -94.558329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918383595, states[0] = -94.887588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928056992, states[0] = 16.344043, states[40]= 0.003545
Saving checkpoint... 
Iteration: 937749235, states[0] = -94.693498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947398819, states[0] = -94.896725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957083533, states[0] = 4.505272, states[40]= 0.004951
Saving checkpoint... 
Iteration: 966817342, states[0] = -94.825074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976451521, states[0] = -94.919557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986092386, states[0] = -0.643641, states[40]= 0.004666
Saving checkpoint... 
Iteration: 995789279, states[0] = -94.782176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005450617, states[0] = -94.919152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015171129, states[0] = -70.081060, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1024831394, states[0] = -94.841904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034499193, states[0] = -94.931742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044147138, states[0] = -45.569958, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1053791366, states[0] = -94.785611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063431879, states[0] = -94.912078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073078059, states[0] = 7.301421, states[40]= 0.004849
Saving checkpoint... 
Iteration: 1082788215, states[0] = -94.779961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092494018, states[0] = -94.930463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102080209, states[0] = 6.231774, states[40]= 0.004907
Saving checkpoint... 
Iteration: 1111807113, states[0] = -94.810421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121464690, states[0] = -94.923082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131080338, states[0] = 6.166521, states[40]= 0.004910
Saving checkpoint... 
Iteration: 1140589226, states[0] = 1.302912, states[40]= 0.004853
Saving checkpoint... 
Iteration: 1150002934, states[0] = 38.981370, states[40]= 0.439476
Saving checkpoint... 
Iteration: 1159450643, states[0] = -94.918595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169001063, states[0] = 48.318075, states[40]= 0.170614
Saving checkpoint... 
Iteration: 1178484333, states[0] = -94.927987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187941772, states[0] = -94.915405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197407158, states[0] = -94.900296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206950508, states[0] = -94.918375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216442664, states[0] = -94.915623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225895329, states[0] = -94.893706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235299205, states[0] = -94.797932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244923673, states[0] = -94.907972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254429184, states[0] = -94.910278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263853700, states[0] = -94.863394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273352928, states[0] = -94.862669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282735971, states[0] = -94.653264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292244655, states[0] = -94.679334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301700691, states[0] = -94.487653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311147455, states[0] = -45.856510, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1320621724, states[0] = -24.160043, states[40]= 0.001554
Saving checkpoint... 
Iteration: 1330096914, states[0] = -3.698683, states[40]= 0.004175
Saving checkpoint... 
Iteration: 1339592223, states[0] = -0.539056, states[40]= 0.004679
Saving checkpoint... 
Iteration: 1349054503, states[0] = 17.283777, states[40]= 0.003347
Saving checkpoint... 
Iteration: 1358480397, states[0] = -94.926383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367982219, states[0] = -94.926790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377400723, states[0] = -94.896202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386936067, states[0] = -94.912538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396449900, states[0] = -94.917476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405907436, states[0] = -94.899672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415384421, states[0] = -94.886298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424902628, states[0] = -94.897067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434398881, states[0] = -94.894968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443866445, states[0] = -94.873369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453358322, states[0] = -94.866716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462850983, states[0] = -94.860206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472367182, states[0] = -94.873837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481834214, states[0] = -94.843344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491262582, states[0] = -94.725481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500741539, states[0] = -95.255633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510208012, states[0] = -95.140840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1519591141, states[0] = 20.978872, states[40]= 0.001619
Saving checkpoint... 
Iteration: 1528931276, states[0] = -87.444552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538319055, states[0] = -94.818445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547714955, states[0] = -94.380352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557148609, states[0] = -36.349794, states[40]= 0.000822
Saving checkpoint... 
Iteration: 1566499641, states[0] = -94.697504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575941127, states[0] = -94.711285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585277283, states[0] = -94.629697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594592391, states[0] = -94.615558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604002741, states[0] = 38.355504, states[40]= 0.439840
Saving checkpoint... 
Iteration: 1613450054, states[0] = -94.555043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622807401, states[0] = -94.331816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632099979, states[0] = -94.517105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641413883, states[0] = -94.518661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650807369, states[0] = -94.522967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660203895, states[0] = -68.979545, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1669562376, states[0] = -94.500867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678963902, states[0] = -94.504805, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.371859
 - CaMKt in component CaMK (millimolar): 0.001131
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.307761
 - nass in component intracellular_ions (millimolar): 6.307847
 - ki in component intracellular_ions (millimolar): 145.591918
 - kss in component intracellular_ions (millimolar): 145.591907
 - cansr in component intracellular_ions (millimolar): 1.562334
 - cajsr in component intracellular_ions (millimolar): 1.562349
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003817
 - hf in component INa (dimensionless): 0.870494
 - hs in component INa (dimensionless): 0.870495
 - j in component INa (dimensionless): 0.870496
 - hsp in component INa (dimensionless): 0.708190
 - jp in component INa (dimensionless): 0.870496
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714973
 - hLp in component INaL (dimensionless): 0.522813
 - a in component Ito (dimensionless): 0.000646
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.997664
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.999223
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998751
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002968
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001876
 - xs1 in component IKs (dimensionless): 0.024491
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997473
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:53:36 (3588): called boinc_finish(0)

</stderr_txt>
]]>


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