𝕏

Task 55968344

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Schmidt_1000-conf_778_1
Workunit 26579239
Created 3 Jul 2024, 18:47:54 UTC
Sent 3 Jul 2024, 20:09:25 UTC
Report deadline 6 Jul 2024, 20:09:25 UTC
Received 7 Jul 2024, 1:43:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241639
Run time 2 hours 21 min 38 sec
CPU time 1 hours 43 min 31 sec
Validate state Valid
Credit 45.31
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.79 MB
Peak swap size 5.30 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Schmidt_1000-conf_778.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Schmidt_1000-conf_778_1_r281111249_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Schmidt_1000-conf_778_1_r281111249_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.332865
     * GNaL_b in INaL: 0.005559
     * Gto_b in Ito: 0.086286
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031995
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.163126
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.340634
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028973
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9773535, states[0] = -84.304604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20759610, states[0] = -84.167186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30622474, states[0] = -33.399615, states[40]= 0.000160
Saving checkpoint... 
Iteration: 40988189, states[0] = -84.484522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49837680, states[0] = -84.346704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59686488, states[0] = -83.630631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69443903, states[0] = -84.450428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79312738, states[0] = -84.284826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89543203, states[0] = 23.144622, states[40]= 0.000016
Saving checkpoint... 
Iteration: 97760046, states[0] = -84.113837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105770208, states[0] = -84.153353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113305058, states[0] = -84.261027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123304387, states[0] = -84.258515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132583243, states[0] = 3.460579, states[40]= 0.000270
Saving checkpoint... 
Iteration: 141196885, states[0] = -83.732571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151152178, states[0] = -62.289149, states[40]= 0.000005
Saving checkpoint... 
Iteration: 161885573, states[0] = -84.394234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171915674, states[0] = -84.421206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180990408, states[0] = -84.460399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189278745, states[0] = -84.179897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195254875, states[0] = -84.086113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205092476, states[0] = -2.568941, states[40]= 0.000395
Saving checkpoint... 
Iteration: 213398617, states[0] = -84.405993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221984876, states[0] = -84.457698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230316839, states[0] = -84.285074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240441072, states[0] = -84.437028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252266800, states[0] = -84.135107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263771988, states[0] = -84.154660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271762489, states[0] = -84.117539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283129270, states[0] = -38.719251, states[40]= 0.000110
Saving checkpoint... 
Iteration: 290683410, states[0] = -83.530135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300011941, states[0] = 31.062170, states[40]= 0.029629
Saving checkpoint... 
Iteration: 310387915, states[0] = -84.394154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319157958, states[0] = -69.051129, states[40]= 0.000002
Saving checkpoint... 
Iteration: 325951851, states[0] = -84.441806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 331421148, states[0] = -84.422767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341301195, states[0] = -84.245412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351289820, states[0] = -84.213061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360534309, states[0] = 26.778880, states[40]= 0.000019
Saving checkpoint... 
Iteration: 368411897, states[0] = -84.415228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 372955673, states[0] = -84.443131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373716623, states[0] = -83.872177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379977456, states[0] = -84.452722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 389984790, states[0] = -84.455355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398579714, states[0] = 5.507290, states[40]= 0.000222
Saving checkpoint... 
Iteration: 408842557, states[0] = -84.332550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417461500, states[0] = -84.445363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424870168, states[0] = -84.372456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430945928, states[0] = -84.437223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434531290, states[0] = 27.885251, states[40]= 0.000038
Saving checkpoint... 
Iteration: 443562378, states[0] = 14.445217, states[40]= 0.000070
Saving checkpoint... 
Iteration: 451571413, states[0] = 9.939225, states[40]= 0.000131
Saving checkpoint... 
Iteration: 460397016, states[0] = -84.401108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467723659, states[0] = -83.916102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474131336, states[0] = -40.760593, states[40]= 0.000089
Saving checkpoint... 
Iteration: 482567178, states[0] = 12.084387, states[40]= 0.000098
Saving checkpoint... 
Iteration: 485423876, states[0] = -84.422670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489096291, states[0] = -5.613247, states[40]= 0.000411
Saving checkpoint... 
Iteration: 493171669, states[0] = -81.833832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498864253, states[0] = -84.363851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503816525, states[0] = -84.280638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508238709, states[0] = -84.002477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512849958, states[0] = -84.343116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517300625, states[0] = -84.241526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524353429, states[0] = -84.348247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531436845, states[0] = -84.430586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541302966, states[0] = -84.247379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550402102, states[0] = -84.404551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561183555, states[0] = -83.530667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571569926, states[0] = 10.700483, states[40]= 0.000119
Saving checkpoint... 
Iteration: 577098188, states[0] = -7.290629, states[40]= 0.000402
Saving checkpoint... 
Iteration: 582690223, states[0] = -83.659949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592275847, states[0] = -84.164132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601949923, states[0] = -84.437128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610760758, states[0] = -84.105739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620562540, states[0] = 14.367678, states[40]= 0.000071
Saving checkpoint... 
Iteration: 630868429, states[0] = -84.367522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639673210, states[0] = -82.345167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648184032, states[0] = -83.543866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651136090, states[0] = -45.483882, states[40]= 0.000051
Saving checkpoint... 
Iteration: 655342568, states[0] = -84.329276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 661616182, states[0] = -25.664043, states[40]= 0.000229
Saving checkpoint... 
Iteration: 670926675, states[0] = -84.422150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678876398, states[0] = -84.376595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687238500, states[0] = -83.998913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695935869, states[0] = -84.427803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703805867, states[0] = -84.252628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713045691, states[0] = 22.122822, states[40]= 0.000020
Saving checkpoint... 
Iteration: 721725810, states[0] = -83.925855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730084492, states[0] = 2.748476, states[40]= 0.000289
Saving checkpoint... 
Iteration: 737806201, states[0] = -84.253011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746255656, states[0] = -84.081896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755536771, states[0] = 25.830295, states[40]= 0.000014
Saving checkpoint... 
Iteration: 765063090, states[0] = 14.101169, states[40]= 0.000074
Saving checkpoint... 
Iteration: 773668222, states[0] = -79.982399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782029434, states[0] = 28.527063, states[40]= 0.000067
Saving checkpoint... 
Iteration: 790565221, states[0] = 13.057165, states[40]= 0.000086
Saving checkpoint... 
Iteration: 798835978, states[0] = -84.315871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806767821, states[0] = -84.131535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815968037, states[0] = -84.443042, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824691699, states[0] = -83.673456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832133780, states[0] = -43.178042, states[40]= 0.000067
Saving checkpoint... 
Iteration: 840822411, states[0] = -84.288877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849927149, states[0] = -84.420097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855115310, states[0] = -24.777610, states[40]= 0.000229
Saving checkpoint... 
Iteration: 862507660, states[0] = 29.757428, states[40]= 0.134525
Saving checkpoint... 
Iteration: 871983560, states[0] = -84.448523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881026252, states[0] = 29.534889, states[40]= 0.000194
Saving checkpoint... 
Iteration: 890635258, states[0] = -44.648008, states[40]= 0.000057
Saving checkpoint... 
Iteration: 899304935, states[0] = -84.247640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909274723, states[0] = -84.155849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919117458, states[0] = -26.944867, states[40]= 0.000227
Saving checkpoint... 
Iteration: 928368990, states[0] = -84.364270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937413644, states[0] = -84.409055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947176305, states[0] = -82.986826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956866525, states[0] = -84.360733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966558995, states[0] = 16.071276, states[40]= 0.000055
Saving checkpoint... 
Iteration: 976793456, states[0] = -84.215390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982406807, states[0] = -84.402887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993403199, states[0] = -84.399633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003369811, states[0] = -84.364304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012200349, states[0] = -83.747219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018250269, states[0] = -84.053560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026632205, states[0] = -41.609643, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1035638834, states[0] = -48.223809, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1046188343, states[0] = -83.627947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055661406, states[0] = -73.219680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1062300248, states[0] = -84.233190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071167164, states[0] = -79.178159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082450133, states[0] = -84.430869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093144469, states[0] = -53.949960, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1102743104, states[0] = -84.017286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108695473, states[0] = -83.705888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119364997, states[0] = -84.356567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129526277, states[0] = 29.528778, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1138308800, states[0] = -84.254069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1147109881, states[0] = -19.182951, states[40]= 0.000235
Saving checkpoint... 
Iteration: 1155661627, states[0] = -73.478421, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165203928, states[0] = -83.772244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175453811, states[0] = -84.431552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184645532, states[0] = -55.047593, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1194209159, states[0] = -83.809712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203068895, states[0] = 11.227028, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1212560780, states[0] = 15.220598, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1223767037, states[0] = -84.122837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235023028, states[0] = 30.405415, states[40]= 0.000593
Saving checkpoint... 
Iteration: 1246389052, states[0] = -84.382866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257956212, states[0] = -84.431668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265788601, states[0] = -84.197033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273293523, states[0] = -84.211592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280561230, states[0] = 15.004691, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1289749670, states[0] = -84.047031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299166860, states[0] = -78.920135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305928953, states[0] = -84.415261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314162458, states[0] = -74.447217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321737955, states[0] = -83.987312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327437140, states[0] = -84.420207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335281411, states[0] = -84.173162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342951676, states[0] = -84.428228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350828240, states[0] = -84.293893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358582426, states[0] = 3.973933, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1366081342, states[0] = 4.597292, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1373883301, states[0] = -84.375116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381801454, states[0] = -84.232112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392145417, states[0] = -54.922162, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1400829844, states[0] = -84.296353, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1412618695, states[0] = -28.176889, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1423820692, states[0] = -84.277426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434654081, states[0] = -64.373144, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1444195598, states[0] = -83.702302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450083035, states[0] = 3.619822, states[40]= 0.000267
Saving checkpoint... 
Iteration: 1456245041, states[0] = -84.022231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466475416, states[0] = -84.437516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477714714, states[0] = -83.844182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490330615, states[0] = -84.296639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499096420, states[0] = -5.708139, states[40]= 0.000410
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.321580
 - CaMKt in component CaMK (millimolar): 0.016853
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.621403
 - nass in component intracellular_ions (millimolar): 6.621522
 - ki in component intracellular_ions (millimolar): 145.162425
 - kss in component intracellular_ions (millimolar): 145.162402
 - cansr in component intracellular_ions (millimolar): 1.795952
 - cajsr in component intracellular_ions (millimolar): 1.740790
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.010496
 - hf in component INa (dimensionless): 0.563154
 - hs in component INa (dimensionless): 0.563121
 - j in component INa (dimensionless): 0.562947
 - hsp in component INa (dimensionless): 0.317520
 - jp in component INa (dimensionless): 0.562822
 - mL in component INaL (dimensionless): 0.000370
 - hL in component INaL (dimensionless): 0.382119
 - hLp in component INaL (dimensionless): 0.181237
 - a in component Ito (dimensionless): 0.001272
 - iF in component Ito (dimensionless): 0.999169
 - iS in component Ito (dimensionless): 0.549755
 - ap in component Ito (dimensionless): 0.000648
 - iFp in component Ito (dimensionless): 0.999169
 - iSp in component Ito (dimensionless): 0.590027
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.908573
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999806
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003522
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.506742
 - xs1 in component IKs (dimensionless): 0.280369
 - xs2 in component IKs (dimensionless): 0.000287
 - xk1 in component IK1 (dimensionless): 0.996842
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
18:43:08 (24400): called boinc_finish(0)

</stderr_txt>
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