𝕏

Task 55967646

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966_1
Workunit 26578890
Created 3 Jul 2024, 18:47:33 UTC
Sent 3 Jul 2024, 20:05:35 UTC
Report deadline 7 Jul 2024, 5:41:35 UTC
Received 5 Jul 2024, 20:31:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233272
Run time 2 hours 10 min 12 sec
CPU time 2 hours 7 min 1 sec
Validate state Valid
Credit 60.41
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 4.50 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966_1_r1898434150_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966_1_r1898434150_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.485877
     * GNaL_b in INaL: 0.005794
     * Gto_b in Ito: 0.080788
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031413
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.166535
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.232795
     * GKb_b in IKb: 0.003837
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030691
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10988898, states[0] = -95.140097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26114898, states[0] = -36.915149, states[40]= 0.000197
Saving checkpoint... 
Iteration: 41764131, states[0] = -94.984627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56875586, states[0] = -95.045700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72385535, states[0] = -95.041998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87840843, states[0] = -95.019158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100254733, states[0] = -94.948091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115284632, states[0] = -94.976976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130354151, states[0] = -95.020014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146107437, states[0] = -26.772605, states[40]= 0.000625


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966_1_r1898434150_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_966_1_r1898434150_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.485877
     * GNaL_b in INaL: 0.005794
     * Gto_b in Ito: 0.080788
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031413
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.166535
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.232795
     * GKb_b in IKb: 0.003837
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030691
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 146107437
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -26.772605 (After loading)
 - states[40]: 0.000625 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 159726925, states[0] = -94.905212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173236008, states[0] = -94.918632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187099955, states[0] = -19.647326, states[40]= 0.000997
Saving checkpoint... 
Iteration: 202057598, states[0] = 8.521479, states[40]= 0.004934
Saving checkpoint... 
Iteration: 216690866, states[0] = -94.837670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226053159, states[0] = 10.348903, states[40]= 0.005003
Saving checkpoint... 
Iteration: 240046512, states[0] = 12.969008, states[40]= 0.005129
Saving checkpoint... 
Iteration: 252314840, states[0] = -94.996518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266290681, states[0] = -94.978677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280785117, states[0] = -94.973904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290477024, states[0] = -95.050288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305782617, states[0] = -94.971651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321667906, states[0] = -94.279953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337398688, states[0] = -95.033917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352365608, states[0] = -95.022540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367165337, states[0] = -93.652371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382777910, states[0] = -94.967252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397918385, states[0] = -95.039154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408021406, states[0] = 21.179664, states[40]= 0.008960
Saving checkpoint... 
Iteration: 422742912, states[0] = -94.927493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438252114, states[0] = -94.939341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453646010, states[0] = -67.597858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469336609, states[0] = -95.009113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484661657, states[0] = -91.488540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500300291, states[0] = -94.986096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515619378, states[0] = -38.123107, states[40]= 0.000170
Saving checkpoint... 
Iteration: 530653609, states[0] = -79.346280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546635636, states[0] = -55.178580, states[40]= 0.000012
Saving checkpoint... 
Iteration: 562376204, states[0] = -95.026440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578430200, states[0] = -95.041777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594238782, states[0] = -94.921697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610386693, states[0] = -95.030025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626829693, states[0] = -95.005245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642305060, states[0] = -94.989520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658057413, states[0] = 8.604555, states[40]= 0.004937
Saving checkpoint... 
Iteration: 673698238, states[0] = -94.852459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689511243, states[0] = 23.299163, states[40]= 0.040085
Saving checkpoint... 
Iteration: 705546592, states[0] = 12.939738, states[40]= 0.005127
Saving checkpoint... 
Iteration: 721233410, states[0] = -94.913857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736639858, states[0] = -59.973114, states[40]= 0.000005
Saving checkpoint... 
Iteration: 751860620, states[0] = -95.020252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768257520, states[0] = -94.945606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784266020, states[0] = -94.955066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800336691, states[0] = -95.008956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816670925, states[0] = -94.600261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832417831, states[0] = -95.038754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848281518, states[0] = -94.970314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864271751, states[0] = -94.960954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880242545, states[0] = -94.926718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895734596, states[0] = -94.915500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911958935, states[0] = -95.047100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922910236, states[0] = -95.036768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933115958, states[0] = -34.800109, states[40]= 0.000267
Saving checkpoint... 
Iteration: 948952222, states[0] = -95.045915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964755387, states[0] = -94.942978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980862625, states[0] = -95.020946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991419310, states[0] = -95.039019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006885057, states[0] = -95.029244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017030040, states[0] = 18.822718, states[40]= 0.006250
Saving checkpoint... 
Iteration: 1032981292, states[0] = -95.050411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048524113, states[0] = 20.515111, states[40]= 0.007638
Saving checkpoint... 
Iteration: 1063831631, states[0] = -95.006062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079887427, states[0] = -95.029981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095656828, states[0] = -85.018942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111751867, states[0] = -94.938627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127750577, states[0] = -94.937017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141739647, states[0] = -94.922575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156804853, states[0] = -94.989059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172631279, states[0] = -50.401605, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1188665561, states[0] = -93.726759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203688195, states[0] = -94.830926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218525203, states[0] = 20.227395, states[40]= 0.007274
Saving checkpoint... 
Iteration: 1233199012, states[0] = -94.853662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248152383, states[0] = -77.224601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262527093, states[0] = 19.702414, states[40]= 0.006785
Saving checkpoint... 
Iteration: 1276901509, states[0] = -95.034159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291610136, states[0] = -29.241899, states[40]= 0.000505
Saving checkpoint... 
Iteration: 1305428212, states[0] = -95.040898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319293782, states[0] = -94.980530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333941217, states[0] = -95.043613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347907446, states[0] = -95.035766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362514534, states[0] = 22.581325, states[40]= 0.020590
Saving checkpoint... 
Iteration: 1376794821, states[0] = -94.981327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391060809, states[0] = 7.157341, states[40]= 0.004877
Saving checkpoint... 
Iteration: 1405299568, states[0] = -94.985000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419570568, states[0] = 2.603034, states[40]= 0.004573
Saving checkpoint... 
Iteration: 1434211840, states[0] = -94.877926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448010534, states[0] = 23.510126, states[40]= 0.047013
Saving checkpoint... 
Iteration: 1462027736, states[0] = 19.516634, states[40]= 0.006648
Saving checkpoint... 
Iteration: 1476332754, states[0] = -95.006431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490947754, states[0] = -95.044773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505396231, states[0] = -95.270132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520317905, states[0] = -95.207073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534922710, states[0] = -63.932913, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1549770896, states[0] = -95.288807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564741611, states[0] = -95.265384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574934462, states[0] = -95.259333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590122355, states[0] = -65.087542, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1604456835, states[0] = 3.605628, states[40]= 0.005281
Saving checkpoint... 
Iteration: 1618780452, states[0] = -95.309509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632893555, states[0] = -95.319362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647259020, states[0] = -95.292165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661663348, states[0] = -95.296426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673995847, states[0] = -95.321562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688087051, states[0] = -95.315703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702576779, states[0] = -12.680503, states[40]= 0.002076
Saving checkpoint... 
Iteration: 1717022675, states[0] = -65.873734, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1731478420, states[0] = -95.168857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746002194, states[0] = 44.558073, states[40]= 0.076468
Saving checkpoint... 
Iteration: 1760569446, states[0] = -95.147273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774965947, states[0] = -95.138123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788820157, states[0] = -95.246373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803548563, states[0] = 11.171635, states[40]= 0.005139
Saving checkpoint... 
Iteration: 1817885113, states[0] = -95.067369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832375232, states[0] = -95.051142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846855480, states[0] = -95.034298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861288149, states[0] = -94.986660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875670328, states[0] = -94.604622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889998543, states[0] = -95.056745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904708847, states[0] = -94.875266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918895269, states[0] = -95.033914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933940758, states[0] = -95.044413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948357675, states[0] = -95.019082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962975838, states[0] = -95.049593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978409462, states[0] = -95.036228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993615431, states[0] = -34.307358, states[40]= 0.000285
Saving checkpoint... 
Iteration: 2008374191, states[0] = -95.024925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023627353, states[0] = -46.221405, states[40]= 0.000051
Saving checkpoint... 
Iteration: 2038837368, states[0] = -95.008569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053567168, states[0] = 4.271974, states[40]= 0.004711
Saving checkpoint... 
Iteration: 2069180603, states[0] = -94.806537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084165559, states[0] = -93.725516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098877572, states[0] = -95.025959, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.927933
 - CaMKt in component CaMK (millimolar): 0.006904
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.575475
 - nass in component intracellular_ions (millimolar): 6.575535
 - ki in component intracellular_ions (millimolar): 145.403151
 - kss in component intracellular_ions (millimolar): 145.403131
 - cansr in component intracellular_ions (millimolar): 1.308661
 - cajsr in component intracellular_ions (millimolar): 1.270815
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880453
 - hs in component INa (dimensionless): 0.880448
 - j in component INa (dimensionless): 0.880420
 - hsp in component INa (dimensionless): 0.726683
 - jp in component INa (dimensionless): 0.880401
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710713
 - hLp in component INaL (dimensionless): 0.453111
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621705
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696608
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935011
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334390
 - xs1 in component IKs (dimensionless): 0.241192
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:30:52 (552): called boinc_finish(0)

</stderr_txt>
]]>


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