𝕏

Task 55967644

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_466_1
Workunit 26578889
Created 3 Jul 2024, 18:47:33 UTC
Sent 3 Jul 2024, 20:05:35 UTC
Report deadline 7 Jul 2024, 5:41:35 UTC
Received 5 Jul 2024, 23:18:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233272
Run time 2 hours 15 min 14 sec
CPU time 2 hours 11 min 5 sec
Validate state Valid
Credit 62.48
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.38 MB
Peak swap size 4.38 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_466.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_466_1_r1922533133_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_466_1_r1922533133_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.455407
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.082560
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031596
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.168003
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.035832
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029918
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10106552, states[0] = -30.337223, states[40]= 0.000418
Saving checkpoint... 
Iteration: 25731265, states[0] = -94.987468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41393122, states[0] = -95.085021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56830077, states[0] = -95.046234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71773068, states[0] = -94.995902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86477746, states[0] = -95.079251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100863442, states[0] = -95.047662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115236634, states[0] = -94.942658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129997508, states[0] = -95.075877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144210698, states[0] = -94.898144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158779450, states[0] = -94.990152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173829581, states[0] = -95.026544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188344522, states[0] = -95.034197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202537424, states[0] = 16.458776, states[40]= 0.005426
Saving checkpoint... 
Iteration: 216914251, states[0] = -95.058976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230760771, states[0] = -94.970046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245451853, states[0] = -95.066945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259763941, states[0] = -94.973482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274185064, states[0] = -94.843319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288643368, states[0] = -63.527475, states[40]= 0.000003
Saving checkpoint... 
Iteration: 303070689, states[0] = 2.829373, states[40]= 0.004570
Saving checkpoint... 
Iteration: 317291966, states[0] = -95.000051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331439485, states[0] = -95.064465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345421133, states[0] = -95.060421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359947394, states[0] = -95.065981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374256466, states[0] = -94.964868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388716855, states[0] = -94.907475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403131775, states[0] = -50.289217, states[40]= 0.000027
Saving checkpoint... 
Iteration: 417453077, states[0] = -95.066980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431580925, states[0] = -3.010769, states[40]= 0.003785
Saving checkpoint... 
Iteration: 446232999, states[0] = -94.933547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461145538, states[0] = -66.288006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 475561098, states[0] = 7.265111, states[40]= 0.004848
Saving checkpoint... 
Iteration: 489613743, states[0] = -32.073481, states[40]= 0.000377
Saving checkpoint... 
Iteration: 503105415, states[0] = -24.190137, states[40]= 0.000749
Saving checkpoint... 
Iteration: 517140503, states[0] = -60.076916, states[40]= 0.000005
Saving checkpoint... 
Iteration: 531465386, states[0] = -95.068976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545773296, states[0] = -94.983003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559903106, states[0] = -95.055595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574057106, states[0] = 8.946797, states[40]= 0.004910
Saving checkpoint... 
Iteration: 587933160, states[0] = -95.062984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602433452, states[0] = -95.063037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616334034, states[0] = -95.028110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630574670, states[0] = 0.741852, states[40]= 0.004353
Saving checkpoint... 
Iteration: 644820692, states[0] = -95.020364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659674208, states[0] = -94.748535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673721130, states[0] = -94.914594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687947338, states[0] = -95.065762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702457445, states[0] = -95.067562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716658475, states[0] = -87.071183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731228013, states[0] = -94.925724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745679259, states[0] = -94.818618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760474792, states[0] = -95.070260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774650832, states[0] = -73.908388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789685211, states[0] = -94.843366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804022432, states[0] = 20.928569, states[40]= 0.008176
Saving checkpoint... 
Iteration: 819123289, states[0] = -41.389546, states[40]= 0.000107
Saving checkpoint... 
Iteration: 834107719, states[0] = -26.362277, states[40]= 0.000647
Saving checkpoint... 
Iteration: 849260793, states[0] = -94.969561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863829296, states[0] = -95.025324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879127833, states[0] = -46.074409, states[40]= 0.000052
Saving checkpoint... 
Iteration: 894196869, states[0] = -94.869411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909063340, states[0] = 6.285413, states[40]= 0.004804
Saving checkpoint... 
Iteration: 923813001, states[0] = -95.015252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938617636, states[0] = -35.811280, states[40]= 0.000236
Saving checkpoint... 
Iteration: 953606007, states[0] = -24.747746, states[40]= 0.000723
Saving checkpoint... 
Iteration: 963769827, states[0] = -94.979231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978503640, states[0] = 33.797447, states[40]= 0.149733
Saving checkpoint... 
Iteration: 993458885, states[0] = -95.067623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008655504, states[0] = -81.950851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023788825, states[0] = -94.996972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038822503, states[0] = -95.021225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053871559, states[0] = -95.044930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069710483, states[0] = -94.895642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084324784, states[0] = -95.022565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095204871, states[0] = -94.885084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110552744, states[0] = 10.711085, states[40]= 0.004968
Saving checkpoint... 
Iteration: 1125847394, states[0] = -95.034589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141116990, states[0] = -35.186730, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1156277490, states[0] = -94.986697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171290383, states[0] = -94.998191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185734704, states[0] = -94.935607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195890528, states[0] = -95.051428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210828561, states[0] = -95.024687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225582817, states[0] = -4.294094, states[40]= 0.003541
Saving checkpoint... 
Iteration: 1241068246, states[0] = 4.027427, states[40]= 0.004667
Saving checkpoint... 
Iteration: 1256721120, states[0] = -94.914209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267007149, states[0] = 25.176248, states[40]= 0.101339
Saving checkpoint... 
Iteration: 1282625635, states[0] = -43.783313, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1298022934, states[0] = 20.810968, states[40]= 0.007937
Saving checkpoint... 
Iteration: 1312190808, states[0] = -94.856455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326899609, states[0] = -95.054110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341823427, states[0] = -95.021592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356169817, states[0] = -94.507397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371000882, states[0] = 46.644249, states[40]= 0.018892
Saving checkpoint... 
Iteration: 1385228344, states[0] = -94.925829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394637716, states[0] = -56.865657, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1408724474, states[0] = -94.919644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423156548, states[0] = -83.817336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437336480, states[0] = -95.028905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451634156, states[0] = -52.890927, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1466280489, states[0] = -94.989313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480703876, states[0] = -94.882924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494558017, states[0] = 8.569533, states[40]= 0.004898
Saving checkpoint... 
Iteration: 1508892428, states[0] = -95.170434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523213298, states[0] = -50.777382, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1537279272, states[0] = -13.825273, states[40]= 0.001848
Saving checkpoint... 
Iteration: 1551918179, states[0] = 21.738147, states[40]= 0.013317
Saving checkpoint... 
Iteration: 1566325451, states[0] = 19.237654, states[40]= 0.008174
Saving checkpoint... 
Iteration: 1581010234, states[0] = 24.131576, states[40]= 0.050375
Saving checkpoint... 
Iteration: 1595731735, states[0] = 16.626952, states[40]= 0.006883
Saving checkpoint... 
Iteration: 1609385382, states[0] = -95.199478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623802790, states[0] = -95.234448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637943846, states[0] = -95.293775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652556408, states[0] = -95.118882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667055018, states[0] = -95.306151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681604674, states[0] = -42.828328, states[40]= 0.000089
Saving checkpoint... 
Iteration: 1694895324, states[0] = -95.221714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708912114, states[0] = -51.715386, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1723626556, states[0] = -71.279366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1737762292, states[0] = -95.144451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751943755, states[0] = -95.294391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766071464, states[0] = -95.321442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780111682, states[0] = -95.250761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793830054, states[0] = -77.332550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807808820, states[0] = -95.059439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822026148, states[0] = 19.604845, states[40]= 0.006763
Saving checkpoint... 
Iteration: 1836312103, states[0] = -95.036971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850829787, states[0] = -95.039878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865532023, states[0] = 18.141302, states[40]= 0.005872
Saving checkpoint... 
Iteration: 1879903694, states[0] = -95.061165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894124472, states[0] = -42.887831, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1907977166, states[0] = -95.072568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917501119, states[0] = 48.845537, states[40]= 0.035543
Saving checkpoint... 
Iteration: 1931980325, states[0] = -95.071605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941236019, states[0] = -94.938052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955659832, states[0] = -89.125627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969847547, states[0] = -95.034522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979343435, states[0] = -95.032410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993366560, states[0] = -95.042566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007761498, states[0] = -94.969716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022485925, states[0] = -95.071042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036766678, states[0] = -94.975268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051147656, states[0] = -69.163254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2065104954, states[0] = -23.756545, states[40]= 0.000769
Saving checkpoint... 
Iteration: 2079278415, states[0] = -94.986953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093258946, states[0] = -94.966627, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.948508
 - CaMKt in component CaMK (millimolar): 0.006975
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.550896
 - nass in component intracellular_ions (millimolar): 6.550956
 - ki in component intracellular_ions (millimolar): 145.426776
 - kss in component intracellular_ions (millimolar): 145.426756
 - cansr in component intracellular_ions (millimolar): 1.311907
 - cajsr in component intracellular_ions (millimolar): 1.273892
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003601
 - hf in component INa (dimensionless): 0.880808
 - hs in component INa (dimensionless): 0.880803
 - j in component INa (dimensionless): 0.880775
 - hsp in component INa (dimensionless): 0.727354
 - jp in component INa (dimensionless): 0.880756
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711141
 - hLp in component INaL (dimensionless): 0.453393
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621237
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696099
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934570
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332430
 - xs1 in component IKs (dimensionless): 0.242538
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:56:06 (15238): called boinc_finish(0)

</stderr_txt>
]]>


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