𝕏

Task 55967616

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_165_1
Workunit 26578875
Created 3 Jul 2024, 18:47:33 UTC
Sent 3 Jul 2024, 20:05:35 UTC
Report deadline 7 Jul 2024, 5:41:35 UTC
Received 5 Jul 2024, 21:41:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233272
Run time 2 hours 14 min 57 sec
CPU time 2 hours 10 min 56 sec
Validate state Valid
Credit 61.33
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.46 MB
Peak swap size 4.60 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_165.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_165_1_r1121576548_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_165_1_r1121576548_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.145585
     * GNaL_b in INaL: 0.006008
     * Gto_b in Ito: 0.083108
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031354
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.164939
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.306879
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035706
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10495499, states[0] = -95.109493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26353085, states[0] = -95.034243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42070321, states[0] = 2.686029, states[40]= 0.004553
Saving checkpoint... 
Iteration: 54129412, states[0] = -47.527551, states[40]= 0.000042
Saving checkpoint... 
Iteration: 69639583, states[0] = -58.036153, states[40]= 0.000007
Saving checkpoint... 
Iteration: 80041299, states[0] = 15.137589, states[40]= 0.005177
Saving checkpoint... 
Iteration: 95133372, states[0] = -50.675844, states[40]= 0.000025
Saving checkpoint... 
Iteration: 111259364, states[0] = -94.916987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126477665, states[0] = -95.019403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141983363, states[0] = -95.019296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157507134, states[0] = 25.017211, states[40]= 0.101182
Saving checkpoint... 
Iteration: 173013606, states[0] = 22.619225, states[40]= 0.023692
Saving checkpoint... 
Iteration: 188279590, states[0] = -94.934745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203657084, states[0] = -81.012486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213815335, states[0] = -94.962875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229593207, states[0] = -11.777201, states[40]= 0.001976
Saving checkpoint... 
Iteration: 245152898, states[0] = -73.985069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260636758, states[0] = -53.877694, states[40]= 0.000015
Saving checkpoint... 
Iteration: 275979624, states[0] = -95.017203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290456208, states[0] = -95.013542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305327872, states[0] = -94.970421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319143263, states[0] = -61.183966, states[40]= 0.000004
Saving checkpoint... 
Iteration: 333139235, states[0] = -56.601669, states[40]= 0.000009
Saving checkpoint... 
Iteration: 347345086, states[0] = -94.979621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361675374, states[0] = -94.655247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375769685, states[0] = -94.924372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390220463, states[0] = -94.857621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404090566, states[0] = -9.490939, states[40]= 0.002426
Saving checkpoint... 
Iteration: 418672555, states[0] = -94.485497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432786889, states[0] = -94.940842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446558978, states[0] = 8.481170, states[40]= 0.004857
Saving checkpoint... 
Iteration: 460935482, states[0] = -95.009452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475289777, states[0] = -94.943313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489266094, states[0] = -94.920470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503851743, states[0] = -94.982696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518142997, states[0] = -60.872661, states[40]= 0.000004
Saving checkpoint... 
Iteration: 532242749, states[0] = -94.891815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546706466, states[0] = -94.832219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561148741, states[0] = -67.986264, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574859845, states[0] = -94.986254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589395975, states[0] = -94.999329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603743776, states[0] = -94.893176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618322167, states[0] = -94.966787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633086449, states[0] = -6.206031, states[40]= 0.003125
Saving checkpoint... 
Iteration: 643241324, states[0] = -94.889767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657501374, states[0] = 48.148309, states[40]= 0.054154
Saving checkpoint... 
Iteration: 671919667, states[0] = -95.005735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686240004, states[0] = -94.887882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700242693, states[0] = -94.891629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714458236, states[0] = -95.013599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728648793, states[0] = -68.055583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737616717, states[0] = -33.557355, states[40]= 0.000319
Saving checkpoint... 
Iteration: 752313771, states[0] = -94.961303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766374136, states[0] = -94.991846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781064842, states[0] = 5.976177, states[40]= 0.004755
Saving checkpoint... 
Iteration: 795504643, states[0] = 29.501758, states[40]= 0.152157
Saving checkpoint... 
Iteration: 809557858, states[0] = 8.940902, states[40]= 0.004872
Saving checkpoint... 
Iteration: 823604599, states[0] = -22.251440, states[40]= 0.000845
Saving checkpoint... 
Iteration: 837410279, states[0] = -95.003239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851781044, states[0] = -94.935286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866320599, states[0] = -94.965653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880538436, states[0] = 16.292411, states[40]= 0.005306
Saving checkpoint... 
Iteration: 894981643, states[0] = -95.017054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909287311, states[0] = -94.940905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923504725, states[0] = 29.256933, states[40]= 0.151192
Saving checkpoint... 
Iteration: 937965462, states[0] = -95.014643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952664395, states[0] = -91.549863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967052376, states[0] = 11.124070, states[40]= 0.004936
Saving checkpoint... 
Iteration: 981137567, states[0] = -54.758576, states[40]= 0.000013
Saving checkpoint... 
Iteration: 995339273, states[0] = -94.976254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010010927, states[0] = 23.137884, states[40]= 0.042061
Saving checkpoint... 
Iteration: 1024659055, states[0] = -84.412312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040029018, states[0] = 19.319408, states[40]= 0.006192
Saving checkpoint... 
Iteration: 1054971306, states[0] = -95.015471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070166439, states[0] = -92.945301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085245546, states[0] = -94.895257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099997013, states[0] = -95.018872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115150307, states[0] = -70.134503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130514420, states[0] = 22.493832, states[40]= 0.020310
Saving checkpoint... 
Iteration: 1145670366, states[0] = -94.207168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160154755, states[0] = -76.971261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175089530, states[0] = -8.630119, states[40]= 0.002607
Saving checkpoint... 
Iteration: 1189500942, states[0] = 46.780571, states[40]= 0.023810
Saving checkpoint... 
Iteration: 1204650307, states[0] = -70.134371, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219590641, states[0] = -9.553595, states[40]= 0.002413
Saving checkpoint... 
Iteration: 1234749852, states[0] = -94.900803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250160835, states[0] = -87.296147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264918495, states[0] = -95.005067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280857307, states[0] = -94.984702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290878593, states[0] = -94.993139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301242947, states[0] = -94.891592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315621980, states[0] = -38.589140, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1330775815, states[0] = -94.929973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345955367, states[0] = -95.012700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360813739, states[0] = -94.960891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375932883, states[0] = -95.008312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388679412, states[0] = -94.745333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404105270, states[0] = -22.874072, states[40]= 0.000815
Saving checkpoint... 
Iteration: 1418952799, states[0] = -95.012199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433818090, states[0] = -94.963698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448694724, states[0] = -94.808243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458553689, states[0] = 10.610314, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1473517128, states[0] = 22.057132, states[40]= 0.013216
Saving checkpoint... 
Iteration: 1488435049, states[0] = -95.008702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502405725, states[0] = 28.340602, states[40]= 0.104949
Saving checkpoint... 
Iteration: 1516420459, states[0] = -95.175125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530574039, states[0] = -95.248767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545149164, states[0] = -94.708757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559542005, states[0] = -92.297918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573903239, states[0] = -39.472863, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1584988917, states[0] = -24.140220, states[40]= 0.000766
Saving checkpoint... 
Iteration: 1599268853, states[0] = -95.268416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613202467, states[0] = -38.906228, states[40]= 0.000157
Saving checkpoint... 
Iteration: 1627166863, states[0] = -95.268430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641427249, states[0] = -69.859257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1655403563, states[0] = 34.952500, states[40]= 0.125583
Saving checkpoint... 
Iteration: 1669374047, states[0] = -95.125272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683309688, states[0] = 24.253814, states[40]= 0.056077
Saving checkpoint... 
Iteration: 1697238119, states[0] = -88.719963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711122920, states[0] = -95.219065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725416817, states[0] = -55.874560, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1739883372, states[0] = -95.147238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754284873, states[0] = -95.150550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768539813, states[0] = 13.058045, states[40]= 0.006075
Saving checkpoint... 
Iteration: 1782912768, states[0] = 23.157360, states[40]= 0.029569
Saving checkpoint... 
Iteration: 1797098958, states[0] = -35.179405, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1811394834, states[0] = -95.044116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826090795, states[0] = -11.314289, states[40]= 0.002085
Saving checkpoint... 
Iteration: 1840755940, states[0] = -94.928750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854925371, states[0] = -95.019787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869227120, states[0] = -94.876675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883515564, states[0] = 22.266254, states[40]= 0.016632
Saving checkpoint... 
Iteration: 1897456658, states[0] = -95.016350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911250543, states[0] = -94.903798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925061215, states[0] = 7.511406, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1939333267, states[0] = -94.973488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953599933, states[0] = -17.956265, states[40]= 0.001129
Saving checkpoint... 
Iteration: 1967857464, states[0] = -94.984757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981831951, states[0] = -94.971927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996491998, states[0] = -95.017843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010877215, states[0] = -94.992260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025107796, states[0] = -25.223952, states[40]= 0.000707
Saving checkpoint... 
Iteration: 2039269356, states[0] = -94.922957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053278600, states[0] = -94.932189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067872989, states[0] = -94.990548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082221759, states[0] = -94.858682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096581188, states[0] = -2.557716, states[40]= 0.003840
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.894406
 - CaMKt in component CaMK (millimolar): 0.007012
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583210
 - nass in component intracellular_ions (millimolar): 6.583269
 - ki in component intracellular_ions (millimolar): 145.394359
 - kss in component intracellular_ions (millimolar): 145.394339
 - cansr in component intracellular_ions (millimolar): 1.311844
 - cajsr in component intracellular_ions (millimolar): 1.273645
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879872
 - hs in component INa (dimensionless): 0.879867
 - j in component INa (dimensionless): 0.879838
 - hsp in component INa (dimensionless): 0.725587
 - jp in component INa (dimensionless): 0.879819
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709243
 - hLp in component INaL (dimensionless): 0.450357
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619025
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.693408
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933570
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999880
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001600
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333139
 - xs1 in component IKs (dimensionless): 0.245029
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:41:03 (12144): called boinc_finish(0)

</stderr_txt>
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