𝕏

Task 55967611

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_864_0
Workunit 26578873
Created 3 Jul 2024, 18:47:33 UTC
Sent 3 Jul 2024, 20:05:35 UTC
Report deadline 7 Jul 2024, 5:41:35 UTC
Received 5 Jul 2024, 6:25:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233272
Run time 2 hours 18 min 56 sec
CPU time 2 hours 15 min 27 sec
Validate state Valid
Credit 61.80
Device peak FLOPS 4.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.39 MB
Peak swap size 4.38 GB
Peak disk usage 0.22 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_864.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_864_0_r611495480_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_864_0_r611495480_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.704089
     * GNaL_b in INaL: 0.006052
     * Gto_b in Ito: 0.081849
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031936
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.159308
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.216158
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033459
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9073553, states[0] = -0.965543, states[40]= 0.004096
Saving checkpoint... 
Iteration: 22510221, states[0] = 23.099485, states[40]= 0.049636
Saving checkpoint... 
Iteration: 35779834, states[0] = -94.973179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48267599, states[0] = -94.947347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60726361, states[0] = -94.882677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73809251, states[0] = -94.969626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87758432, states[0] = -94.917663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101542419, states[0] = 14.682733, states[40]= 0.005189
Saving checkpoint... 
Iteration: 115579999, states[0] = -2.432076, states[40]= 0.003883
Saving checkpoint... 
Iteration: 129408967, states[0] = -95.005350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142826831, states[0] = -94.970218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156559698, states[0] = 7.931410, states[40]= 0.004869
Saving checkpoint... 
Iteration: 170093196, states[0] = -12.668837, states[40]= 0.001826
Saving checkpoint... 
Iteration: 183812048, states[0] = -94.959419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192439719, states[0] = -95.010658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206202252, states[0] = -94.819450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219704012, states[0] = -94.822885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233162114, states[0] = -90.583651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246609337, states[0] = -27.822229, states[40]= 0.000573
Saving checkpoint... 
Iteration: 259804304, states[0] = -94.953297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273470141, states[0] = -95.015758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286644619, states[0] = -64.803316, states[40]= 0.000002
Saving checkpoint... 
Iteration: 300360741, states[0] = -94.985954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313441691, states[0] = -95.010615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326753127, states[0] = -94.902532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340253361, states[0] = -94.902818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353867305, states[0] = -94.988680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367348524, states[0] = -94.980253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380943623, states[0] = -95.010954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394806759, states[0] = -94.954992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407758356, states[0] = -94.908948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420977052, states[0] = -95.016676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434441865, states[0] = -95.010565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447921361, states[0] = -95.005957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461259808, states[0] = -94.910651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474473991, states[0] = -95.016188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487864182, states[0] = -94.987297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501630711, states[0] = -49.076992, states[40]= 0.000032
Saving checkpoint... 
Iteration: 514585337, states[0] = -6.021902, states[40]= 0.003179
Saving checkpoint... 
Iteration: 527645910, states[0] = -66.422083, states[40]= 0.000002
Saving checkpoint... 
Iteration: 541173378, states[0] = -94.596848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554595321, states[0] = -14.586869, states[40]= 0.001523
Saving checkpoint... 
Iteration: 567193400, states[0] = -94.800432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580569304, states[0] = 3.605543, states[40]= 0.004628
Saving checkpoint... 
Iteration: 593809486, states[0] = -94.956851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607151727, states[0] = -74.570117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620649293, states[0] = -70.963960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633270164, states[0] = -94.922211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646752277, states[0] = -94.901240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660536870, states[0] = 16.753867, states[40]= 0.005463
Saving checkpoint... 
Iteration: 674117123, states[0] = -35.256672, states[40]= 0.000251
Saving checkpoint... 
Iteration: 687919011, states[0] = -95.005222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701634124, states[0] = -52.776090, states[40]= 0.000018
Saving checkpoint... 
Iteration: 714555222, states[0] = 9.807702, states[40]= 0.004932
Saving checkpoint... 
Iteration: 727456950, states[0] = -95.013247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736516942, states[0] = 22.148203, states[40]= 0.013795
Saving checkpoint... 
Iteration: 749859666, states[0] = -94.985189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763284559, states[0] = -94.936426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777269396, states[0] = -94.921298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790230440, states[0] = -94.869834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803931386, states[0] = -95.008095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817283183, states[0] = -94.935115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830997909, states[0] = -95.019190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844688891, states[0] = -94.789714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857359434, states[0] = -94.985020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870983602, states[0] = -95.017327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884358108, states[0] = -94.984414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897870192, states[0] = -94.989505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911572013, states[0] = 2.247408, states[40]= 0.004509
Saving checkpoint... 
Iteration: 924987505, states[0] = -95.017820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938499004, states[0] = -95.019254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952016893, states[0] = 22.156953, states[40]= 0.013888
Saving checkpoint... 
Iteration: 966144012, states[0] = -64.055050, states[40]= 0.000003
Saving checkpoint... 
Iteration: 979706888, states[0] = -94.827905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993424854, states[0] = -95.006466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007499873, states[0] = -95.019314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021233196, states[0] = -94.874026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035282060, states[0] = -94.933923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049393584, states[0] = -94.997770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063593761, states[0] = -13.146229, states[40]= 0.001745
Saving checkpoint... 
Iteration: 1076926037, states[0] = -95.006695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090639733, states[0] = -59.025044, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1103996411, states[0] = -95.018840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118029897, states[0] = 19.026254, states[40]= 0.006156
Saving checkpoint... 
Iteration: 1131505030, states[0] = 28.734505, states[40]= 0.144439
Saving checkpoint... 
Iteration: 1144843389, states[0] = -94.977190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158318031, states[0] = -94.962380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172005567, states[0] = 27.513194, states[40]= 0.134795
Saving checkpoint... 
Iteration: 1181949792, states[0] = -95.011657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196185428, states[0] = -94.779518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210096838, states[0] = -16.004495, states[40]= 0.001335
Saving checkpoint... 
Iteration: 1224140312, states[0] = -59.687423, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1238155798, states[0] = -81.264875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251470191, states[0] = -95.015125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265333778, states[0] = -94.971931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278948018, states[0] = -95.011259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292929277, states[0] = -95.007314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303752869, states[0] = -94.901588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316584327, states[0] = -5.269470, states[40]= 0.003337
Saving checkpoint... 
Iteration: 1330521806, states[0] = 21.174015, states[40]= 0.008529
Saving checkpoint... 
Iteration: 1343990050, states[0] = -95.017894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357156945, states[0] = -83.218264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370587962, states[0] = -8.088184, states[40]= 0.002735
Saving checkpoint... 
Iteration: 1384133557, states[0] = -52.156179, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1397892151, states[0] = -94.997093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408001231, states[0] = 48.708872, states[40]= 0.042923
Saving checkpoint... 
Iteration: 1421704557, states[0] = -94.823041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435826175, states[0] = -94.967367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449315704, states[0] = -94.960647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462922340, states[0] = -95.005568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472292813, states[0] = -94.943287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487355994, states[0] = -94.983087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502803045, states[0] = -37.013961, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1518291709, states[0] = -95.259666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533643748, states[0] = 11.370436, states[40]= 0.005891
Saving checkpoint... 
Iteration: 1549420531, states[0] = -95.209560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563876830, states[0] = -95.279616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576252939, states[0] = 6.196966, states[40]= 0.005479
Saving checkpoint... 
Iteration: 1591637713, states[0] = -89.246161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605900883, states[0] = 46.037502, states[40]= 0.014960
Saving checkpoint... 
Iteration: 1620732521, states[0] = -80.805626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636282215, states[0] = -18.036086, states[40]= 0.001243
Saving checkpoint... 
Iteration: 1651251395, states[0] = 6.942048, states[40]= 0.005546
Saving checkpoint... 
Iteration: 1666286411, states[0] = -22.653850, states[40]= 0.000850
Saving checkpoint... 
Iteration: 1681598901, states[0] = -36.304490, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1696423905, states[0] = -95.230621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711715667, states[0] = -95.217983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727170048, states[0] = -5.671711, states[40]= 0.003674
Saving checkpoint... 
Iteration: 1742538461, states[0] = -90.470913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758065745, states[0] = -2.155197, states[40]= 0.004431
Saving checkpoint... 
Iteration: 1772851964, states[0] = -94.995901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788125878, states[0] = -69.782221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1803546444, states[0] = 12.289685, states[40]= 0.005111
Saving checkpoint... 
Iteration: 1819000374, states[0] = -48.744046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834142589, states[0] = -64.579646, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1849407348, states[0] = -95.018434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864114192, states[0] = -33.088720, states[40]= 0.000331
Saving checkpoint... 
Iteration: 1879144051, states[0] = -64.707307, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1894370551, states[0] = -94.993520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909747684, states[0] = -94.897314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924806444, states[0] = -94.955626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940195815, states[0] = -94.805944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955339946, states[0] = -94.975594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970718575, states[0] = -94.849539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985864327, states[0] = -94.986686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001149514, states[0] = -71.296663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2016837108, states[0] = -94.973388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032168572, states[0] = -94.055932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047433396, states[0] = -95.007768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062836552, states[0] = -94.972961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077675683, states[0] = -94.682478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093100296, states[0] = -19.267488, states[40]= 0.001019
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.894485
 - CaMKt in component CaMK (millimolar): 0.006924
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.571386
 - nass in component intracellular_ions (millimolar): 6.571445
 - ki in component intracellular_ions (millimolar): 145.407168
 - kss in component intracellular_ions (millimolar): 145.407149
 - cansr in component intracellular_ions (millimolar): 1.308311
 - cajsr in component intracellular_ions (millimolar): 1.270349
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879873
 - hs in component INa (dimensionless): 0.879868
 - j in component INa (dimensionless): 0.879839
 - hsp in component INa (dimensionless): 0.725589
 - jp in component INa (dimensionless): 0.879819
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709555
 - hLp in component INaL (dimensionless): 0.451267
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620565
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695156
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934275
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333320
 - xs1 in component IKs (dimensionless): 0.242978
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:30:54 (27426): called boinc_finish(0)

</stderr_txt>
]]>


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