𝕏

Task 55966943

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_825_0
Workunit 26578539
Created 3 Jul 2024, 18:47:08 UTC
Sent 3 Jul 2024, 19:59:48 UTC
Report deadline 7 Jul 2024, 5:35:48 UTC
Received 5 Jul 2024, 2:57:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238783
Run time 2 hours 32 min 21 sec
CPU time 50 min 50 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.59 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 5.31 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_825.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_825_0_r1529622417_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_825_0_r1529622417_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.947209
     * GNaL_b in INaL: 0.006236
     * Gto_b in Ito: 0.082744
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031806
     * GKs_b in IKs: 0.001974
     * GK1_b in IK1: 0.160620
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.092983
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032294
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18054432, states[0] = 9.115972, states[40]= 0.004923
Saving checkpoint... 
Iteration: 32734748, states[0] = -94.937393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46990713, states[0] = -95.062548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61368741, states[0] = -95.023436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76347143, states[0] = -95.007342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90586792, states[0] = -6.995720, states[40]= 0.002976
Saving checkpoint... 
Iteration: 105733851, states[0] = -94.896318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120634675, states[0] = -52.641401, states[40]= 0.000018
Saving checkpoint... 
Iteration: 134797103, states[0] = -94.965870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149304567, states[0] = -94.971020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163598434, states[0] = -16.915209, states[40]= 0.001234
Saving checkpoint... 
Iteration: 177581786, states[0] = -3.121142, states[40]= 0.003758
Saving checkpoint... 
Iteration: 192219498, states[0] = -94.868009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206282040, states[0] = -94.950775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220650144, states[0] = -71.025788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235162650, states[0] = -90.410568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248840748, states[0] = -94.992717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263211100, states[0] = -94.852224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278078654, states[0] = -1.132966, states[40]= 0.004090
Saving checkpoint... 
Iteration: 291921681, states[0] = -95.022561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306927954, states[0] = -95.024049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321613410, states[0] = -30.924603, states[40]= 0.000432
Saving checkpoint... 
Iteration: 335351636, states[0] = -94.998076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350076650, states[0] = 0.036105, states[40]= 0.004255
Saving checkpoint... 
Iteration: 364825951, states[0] = -94.984137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378550545, states[0] = 11.838354, states[40]= 0.004989
Saving checkpoint... 
Iteration: 393369582, states[0] = -95.005907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407914821, states[0] = -95.020719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422083708, states[0] = -4.407881, states[40]= 0.003511
Saving checkpoint... 
Iteration: 437258220, states[0] = -94.924764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451006504, states[0] = 25.929458, states[40]= 0.115565
Saving checkpoint... 
Iteration: 465509668, states[0] = 23.640600, states[40]= 0.056833
Saving checkpoint... 
Iteration: 480162933, states[0] = -90.694285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494494775, states[0] = -95.035493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508971247, states[0] = -95.032205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523567385, states[0] = 4.769487, states[40]= 0.004709
Saving checkpoint... 
Iteration: 537508068, states[0] = 24.442471, states[40]= 0.082487
Saving checkpoint... 
Iteration: 552359124, states[0] = -95.001382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567013329, states[0] = 22.763443, states[40]= 0.025324
Saving checkpoint... 
Iteration: 581428032, states[0] = -95.023881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596427783, states[0] = -95.023813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610835544, states[0] = -94.989586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625254453, states[0] = -94.919991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639819763, states[0] = -94.980053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654589264, states[0] = -8.657698, states[40]= 0.002612
Saving checkpoint... 
Iteration: 669518984, states[0] = 21.794124, states[40]= 0.010744
Saving checkpoint... 
Iteration: 683788455, states[0] = -94.956120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698354262, states[0] = -94.999079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712773144, states[0] = -94.941358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727316701, states[0] = -94.977975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741724247, states[0] = -94.875504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757065601, states[0] = 5.589089, states[40]= 0.004758
Saving checkpoint... 
Iteration: 771672992, states[0] = -94.553143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786293309, states[0] = -94.960270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800648318, states[0] = -68.478220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814811573, states[0] = -94.974391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829670474, states[0] = -94.292466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844180524, states[0] = -94.767478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859273867, states[0] = -94.942015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874820689, states[0] = -94.980505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888802195, states[0] = -94.967407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903551389, states[0] = 11.510668, states[40]= 0.004977
Saving checkpoint... 
Iteration: 918097664, states[0] = -16.148532, states[40]= 0.001319
Saving checkpoint... 
Iteration: 932097641, states[0] = -16.127091, states[40]= 0.001322
Saving checkpoint... 
Iteration: 946251773, states[0] = -94.916366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961150193, states[0] = -71.077808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975446406, states[0] = -95.027563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989675678, states[0] = -94.682536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003803467, states[0] = -94.968314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017656353, states[0] = -80.899808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032300121, states[0] = -94.965693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047313986, states[0] = -94.975927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061482006, states[0] = -95.033447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075681336, states[0] = -94.773815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089939100, states[0] = -95.026008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104289485, states[0] = -94.956765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118927518, states[0] = -95.023422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132962596, states[0] = -95.030411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147597516, states[0] = -16.010524, states[40]= 0.001336
Saving checkpoint... 
Iteration: 1162583862, states[0] = -4.515837, states[40]= 0.003490
Saving checkpoint... 
Iteration: 1176721860, states[0] = -94.871135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191085832, states[0] = -5.948700, states[40]= 0.003194
Saving checkpoint... 
Iteration: 1205737110, states[0] = -94.895750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219886097, states[0] = -95.011536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233954090, states[0] = -95.028854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248902019, states[0] = -95.016609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263183321, states[0] = -94.785565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277423559, states[0] = -95.022378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291083125, states[0] = -4.002472, states[40]= 0.003591
Saving checkpoint... 
Iteration: 1305403961, states[0] = -95.017144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319655606, states[0] = -79.617261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334643913, states[0] = -62.900575, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1349468937, states[0] = -95.031312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364169093, states[0] = -94.042892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378607455, states[0] = -25.320322, states[40]= 0.000701
Saving checkpoint... 
Iteration: 1393069233, states[0] = 3.894896, states[40]= 0.004648
Saving checkpoint... 
Iteration: 1407974024, states[0] = -95.032064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422222741, states[0] = -94.872500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436448870, states[0] = -95.027750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451057066, states[0] = 9.248432, states[40]= 0.004907
Saving checkpoint... 
Iteration: 1465407173, states[0] = -95.017965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480112699, states[0] = -30.251488, states[40]= 0.000464
Saving checkpoint... 
Iteration: 1494349323, states[0] = -94.996221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508939195, states[0] = -95.213683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523518400, states[0] = -56.175055, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1538375369, states[0] = -95.279411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552935198, states[0] = -83.291099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567090388, states[0] = -95.175237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581033478, states[0] = 16.043246, states[40]= 0.006652
Saving checkpoint... 
Iteration: 1595680330, states[0] = -95.302437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610662160, states[0] = -95.287878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625490474, states[0] = -26.424926, states[40]= 0.000642
Saving checkpoint... 
Iteration: 1640302039, states[0] = -95.206828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654695843, states[0] = -95.195110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669064918, states[0] = -95.121232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684282143, states[0] = -17.455643, states[40]= 0.001312
Saving checkpoint... 
Iteration: 1698727938, states[0] = -72.015542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1713512013, states[0] = -95.225274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727284926, states[0] = -95.172328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741510337, states[0] = 24.087647, states[40]= 0.049155
Saving checkpoint... 
Iteration: 1756497533, states[0] = -95.318357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770933301, states[0] = 16.049231, states[40]= 0.006670
Saving checkpoint... 
Iteration: 1785362599, states[0] = 0.366808, states[40]= 0.004859
Saving checkpoint... 
Iteration: 1799992318, states[0] = -95.314790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814484771, states[0] = -95.079027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829367246, states[0] = -95.034395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844138004, states[0] = -57.615801, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1859106668, states[0] = -25.305977, states[40]= 0.000700
Saving checkpoint... 
Iteration: 1873412850, states[0] = -95.027545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887757954, states[0] = -94.929015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902394004, states[0] = -95.017225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916937243, states[0] = -95.027354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931398532, states[0] = -95.016589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945350667, states[0] = -94.997544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960215817, states[0] = -94.860493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974066716, states[0] = 5.070035, states[40]= 0.004728
Saving checkpoint... 
Iteration: 1988476130, states[0] = -95.032244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002979345, states[0] = -95.032606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017137156, states[0] = -55.155072, states[40]= 0.000012
Saving checkpoint... 
Iteration: 2031582126, states[0] = -3.328366, states[40]= 0.003719
Saving checkpoint... 
Iteration: 2045803660, states[0] = -94.967800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059683186, states[0] = -94.784367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074673777, states[0] = -94.601125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089081874, states[0] = -3.158656, states[40]= 0.003750
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.910945
 - CaMKt in component CaMK (millimolar): 0.006994
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.575617
 - nass in component intracellular_ions (millimolar): 6.575677
 - ki in component intracellular_ions (millimolar): 145.401914
 - kss in component intracellular_ions (millimolar): 145.401895
 - cansr in component intracellular_ions (millimolar): 1.312501
 - cajsr in component intracellular_ions (millimolar): 1.274380
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880158
 - hs in component INa (dimensionless): 0.880154
 - j in component INa (dimensionless): 0.880124
 - hsp in component INa (dimensionless): 0.726127
 - jp in component INa (dimensionless): 0.880105
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709798
 - hLp in component INaL (dimensionless): 0.451196
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619783
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694251
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933651
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334464
 - xs1 in component IKs (dimensionless): 0.244454
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:56:57 (1956): called boinc_finish(0)

</stderr_txt>
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