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Task 55966884

Name HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_20_1
Workunit 26578509
Created 3 Jul 2024, 18:47:08 UTC
Sent 3 Jul 2024, 20:06:12 UTC
Report deadline 7 Jul 2024, 5:42:12 UTC
Received 4 Jul 2024, 0:20:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218513
Run time 1 hours 3 min 18 sec
CPU time 56 min 40 sec
Validate state Valid
Credit 59.31
Device peak FLOPS 4.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.02 MB
Peak swap size 391.75 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_20.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_20_1_r108780643_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204657424929_ORdGradInc_k_26-Pueyo_APDR-conf_20_1_r108780643_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.193896
     * GNaL_b in INaL: 0.005625
     * Gto_b in Ito: 0.084138
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031828
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.159297
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.513559
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033742
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 27907645, states[0] = -95.058027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56590318, states[0] = -11.812787, states[40]= 0.001994
Saving checkpoint... 
Iteration: 82181860, states[0] = -94.782559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107793137, states[0] = -94.954421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135784147, states[0] = -94.943907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162317209, states[0] = -94.968956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191159833, states[0] = -88.951171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217855559, states[0] = -94.989531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244313518, states[0] = -94.965565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273685183, states[0] = -94.784418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301899024, states[0] = -95.005687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327347737, states[0] = -94.985553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354748263, states[0] = -94.901471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380237165, states[0] = -94.885688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407403022, states[0] = -95.006801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434190858, states[0] = -94.799307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462080703, states[0] = -3.305308, states[40]= 0.003729
Saving checkpoint... 
Iteration: 489750145, states[0] = -94.903882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516594777, states[0] = -14.898259, states[40]= 0.001482
Saving checkpoint... 
Iteration: 541044135, states[0] = 13.794506, states[40]= 0.005109
Saving checkpoint... 
Iteration: 567360557, states[0] = -94.991370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593991567, states[0] = -95.024379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620553942, states[0] = 9.985938, states[40]= 0.004931
Saving checkpoint... 
Iteration: 648377330, states[0] = -94.998114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674785657, states[0] = -94.942964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700502260, states[0] = 42.657927, states[40]= 0.103766
Saving checkpoint... 
Iteration: 726666950, states[0] = -93.872409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753374372, states[0] = -94.996925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778889115, states[0] = -95.002200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806910030, states[0] = -95.008537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833918360, states[0] = -95.010725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860155723, states[0] = -82.572088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888694289, states[0] = -94.806724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917137832, states[0] = -57.917514, states[40]= 0.000007
Saving checkpoint... 
Iteration: 944403832, states[0] = -95.006694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974424093, states[0] = -95.012056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003094697, states[0] = -14.823029, states[40]= 0.001493
Saving checkpoint... 
Iteration: 1030686202, states[0] = -94.787001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057842753, states[0] = -94.982548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085124497, states[0] = -43.583930, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1112144308, states[0] = -65.511418, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1138935849, states[0] = -95.014639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164726067, states[0] = -94.867581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192267700, states[0] = -94.924588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218216867, states[0] = -94.851490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244959910, states[0] = -95.019234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271381995, states[0] = -94.999422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298528024, states[0] = 19.246494, states[40]= 0.006409
Saving checkpoint... 
Iteration: 1324403897, states[0] = -95.006470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352353847, states[0] = -94.987831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377849337, states[0] = -94.985661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404115097, states[0] = -34.252508, states[40]= 0.000285
Saving checkpoint... 
Iteration: 1431364562, states[0] = -94.992540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457755879, states[0] = -94.910594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483364678, states[0] = -94.992556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509152397, states[0] = -94.878164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535606689, states[0] = -95.183364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560734025, states[0] = -83.888189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587693516, states[0] = -31.048032, states[40]= 0.000410
Saving checkpoint... 
Iteration: 1613636559, states[0] = -95.251974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639006331, states[0] = -45.699185, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1666887191, states[0] = -24.334240, states[40]= 0.000747
Saving checkpoint... 
Iteration: 1693984142, states[0] = -95.162875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720566692, states[0] = -3.371581, states[40]= 0.004190
Saving checkpoint... 
Iteration: 1749204586, states[0] = -95.204748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775745510, states[0] = 9.777869, states[40]= 0.005782
Saving checkpoint... 
Iteration: 1802192478, states[0] = -94.857322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827347941, states[0] = -95.017376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852836111, states[0] = -94.994085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881167179, states[0] = -94.049291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908424491, states[0] = -95.014562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936074734, states[0] = 0.311964, states[40]= 0.004297
Saving checkpoint... 
Iteration: 1962540010, states[0] = 15.306318, states[40]= 0.005259
Saving checkpoint... 
Iteration: 1987563312, states[0] = 6.016008, states[40]= 0.004781
Saving checkpoint... 
Iteration: 2013318929, states[0] = -94.968084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039030995, states[0] = 18.360793, states[40]= 0.005961
Saving checkpoint... 
Iteration: 2066062467, states[0] = 6.397852, states[40]= 0.004799
Saving checkpoint... 
Iteration: 2094406425, states[0] = -95.006663, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.900286
 - CaMKt in component CaMK (millimolar): 0.006977
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.586495
 - nass in component intracellular_ions (millimolar): 6.586555
 - ki in component intracellular_ions (millimolar): 145.390942
 - kss in component intracellular_ions (millimolar): 145.390923
 - cansr in component intracellular_ions (millimolar): 1.312521
 - cajsr in component intracellular_ions (millimolar): 1.274587
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879974
 - hs in component INa (dimensionless): 0.879969
 - j in component INa (dimensionless): 0.879939
 - hsp in component INa (dimensionless): 0.725779
 - jp in component INa (dimensionless): 0.879920
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709898
 - hLp in component INaL (dimensionless): 0.452006
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621608
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696513
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935613
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331115
 - xs1 in component IKs (dimensionless): 0.240695
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:08:52 (21442): called boinc_finish(0)

</stderr_txt>
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