𝕏

Task 55965097

Name HuVeMOp_20240703204544086228_ORdGradInc_k_26-Pueyo_APDR-conf_154_0
Workunit 26577616
Created 3 Jul 2024, 18:46:11 UTC
Sent 3 Jul 2024, 19:44:30 UTC
Report deadline 7 Jul 2024, 5:20:30 UTC
Received 4 Jul 2024, 2:38:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236853
Run time 2 hours 54 min 49 sec
CPU time 2 hours 54 min 43 sec
Validate state Valid
Credit 59.48
Device peak FLOPS 3.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.02 MB
Peak swap size 2.31 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204544086228_ORdGradInc_k_26-Pueyo_APDR-conf_154.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204544086228_ORdGradInc_k_26-Pueyo_APDR-conf_154_0_r1792133432_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703204544086228_ORdGradInc_k_26-Pueyo_APDR-conf_154_0_r1792133432_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.019212
     * GNaL_b in INaL: 0.006170
     * Gto_b in Ito: 0.087629
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031998
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.166904
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.476807
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030981
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13164626, states[0] = -94.388124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26299540, states[0] = -95.038113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39434619, states[0] = -95.078767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52570310, states[0] = 2.999847, states[40]= 0.004546
Saving checkpoint... 
Iteration: 62635520, states[0] = -53.806576, states[40]= 0.000015
Saving checkpoint... 
Iteration: 75561153, states[0] = 7.416955, states[40]= 0.004783
Saving checkpoint... 
Iteration: 88713876, states[0] = -94.888535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101770103, states[0] = -94.966044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114953549, states[0] = -95.053947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128140350, states[0] = -58.188927, states[40]= 0.000007
Saving checkpoint... 
Iteration: 141329382, states[0] = -95.009728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154519206, states[0] = 21.362972, states[40]= 0.010048
Saving checkpoint... 
Iteration: 167708300, states[0] = -94.871456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180896049, states[0] = -95.037362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194084292, states[0] = -4.524217, states[40]= 0.003462
Saving checkpoint... 
Iteration: 207238842, states[0] = -94.922396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220425936, states[0] = -95.045072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233612939, states[0] = -29.908591, states[40]= 0.000483
Saving checkpoint... 
Iteration: 246772208, states[0] = -94.963336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259958581, states[0] = -95.051532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273114207, states[0] = -31.095852, states[40]= 0.000427
Saving checkpoint... 
Iteration: 286301237, states[0] = -94.989245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299476142, states[0] = -95.054270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308598733, states[0] = -16.662032, states[40]= 0.001254
Saving checkpoint... 
Iteration: 321676804, states[0] = -94.747085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334815854, states[0] = -94.999670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347955163, states[0] = -95.050831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361073739, states[0] = 1.819788, states[40]= 0.004421
Saving checkpoint... 
Iteration: 374198284, states[0] = -94.850689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387332488, states[0] = -95.009847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400422863, states[0] = -95.044077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413576369, states[0] = 0.411364, states[40]= 0.004264
Saving checkpoint... 
Iteration: 414148066, states[0] = -67.434118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427158703, states[0] = -84.548465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440311857, states[0] = -94.996879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453337821, states[0] = -95.012740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466404889, states[0] = -95.039324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480514333, states[0] = 22.081748, states[40]= 0.020271
Saving checkpoint... 
Iteration: 493552989, states[0] = 10.913145, states[40]= 0.004865
Saving checkpoint... 
Iteration: 506531163, states[0] = 18.541280, states[40]= 0.005734
Saving checkpoint... 
Iteration: 519546867, states[0] = 13.221493, states[40]= 0.004936
Saving checkpoint... 
Iteration: 532666902, states[0] = -93.439985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545776110, states[0] = -94.967019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558915708, states[0] = -95.042189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571973991, states[0] = -95.053753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585023136, states[0] = 20.612599, states[40]= 0.007468
Saving checkpoint... 
Iteration: 598057670, states[0] = 9.068428, states[40]= 0.004823
Saving checkpoint... 
Iteration: 611086722, states[0] = -6.281150, states[40]= 0.003100
Saving checkpoint... 
Iteration: 624135724, states[0] = -52.832612, states[40]= 0.000018
Saving checkpoint... 
Iteration: 637226120, states[0] = -94.902196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650360589, states[0] = -95.023582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663365093, states[0] = -95.025475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676391710, states[0] = -95.035193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689464159, states[0] = -95.052134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702584507, states[0] = -4.662556, states[40]= 0.003434
Saving checkpoint... 
Iteration: 715691074, states[0] = -94.834937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728771288, states[0] = -94.961984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741653134, states[0] = -74.882617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754725686, states[0] = -94.901400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767849714, states[0] = -95.018558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780941135, states[0] = -95.047862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794044959, states[0] = 13.920732, states[40]= 0.004972
Saving checkpoint... 
Iteration: 807070746, states[0] = 3.323881, states[40]= 0.004554
Saving checkpoint... 
Iteration: 820205703, states[0] = -94.865279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833230355, states[0] = -94.908888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846323235, states[0] = -95.004057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859185803, states[0] = -94.821041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868385434, states[0] = -95.032984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881339244, states[0] = -95.013207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889243631, states[0] = -94.928506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902174749, states[0] = -94.687559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915318222, states[0] = -95.000829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928462058, states[0] = -95.051624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941615038, states[0] = -31.876436, states[40]= 0.000391
Saving checkpoint... 
Iteration: 954768621, states[0] = -94.959009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967914726, states[0] = -95.041657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981061438, states[0] = 7.517976, states[40]= 0.004779
Saving checkpoint... 
Iteration: 994230764, states[0] = -94.909422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007401625, states[0] = -95.038014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020576511, states[0] = 0.332874, states[40]= 0.004254
Saving checkpoint... 
Iteration: 1033710122, states[0] = -94.873632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046880592, states[0] = -95.031173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059999709, states[0] = -95.056834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073088776, states[0] = -7.881834, states[40]= 0.002759
Saving checkpoint... 
Iteration: 1086179479, states[0] = -94.785948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099315538, states[0] = -94.998935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112460302, states[0] = -95.051203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125624642, states[0] = -41.157327, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1138783117, states[0] = -94.973333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151942023, states[0] = -95.047790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165054350, states[0] = 10.385004, states[40]= 0.004853
Saving checkpoint... 
Iteration: 1166455213, states[0] = -95.050281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179491402, states[0] = -95.055741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192616068, states[0] = -32.849285, states[40]= 0.000349
Saving checkpoint... 
Iteration: 1205749808, states[0] = -94.936581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218902480, states[0] = -95.038121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232000504, states[0] = -22.455202, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1245126969, states[0] = -43.514069, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1258225639, states[0] = -94.900978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271383282, states[0] = -95.031969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284516389, states[0] = 21.806857, states[40]= 0.014305
Saving checkpoint... 
Iteration: 1297672538, states[0] = -94.565807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310828050, states[0] = -95.006653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323981211, states[0] = -95.054286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337134639, states[0] = -51.644097, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1350286289, states[0] = -94.976076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363422058, states[0] = -95.043228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376563472, states[0] = 6.651125, states[40]= 0.004747
Saving checkpoint... 
Iteration: 1389731093, states[0] = -94.909669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402899391, states[0] = -95.037084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416039983, states[0] = 15.691560, states[40]= 0.005119
Saving checkpoint... 
Iteration: 1429180024, states[0] = -94.790844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442355465, states[0] = -95.020778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455468258, states[0] = -95.052273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468527667, states[0] = 19.520011, states[40]= 0.006231
Saving checkpoint... 
Iteration: 1481588072, states[0] = -7.322292, states[40]= 0.002879
Saving checkpoint... 
Iteration: 1494648903, states[0] = -68.569181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1507687812, states[0] = -95.142224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520772628, states[0] = -5.959194, states[40]= 0.003555
Saving checkpoint... 
Iteration: 1533857666, states[0] = -95.270259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546877493, states[0] = -11.503776, states[40]= 0.002292
Saving checkpoint... 
Iteration: 1559901464, states[0] = -95.206251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572986135, states[0] = -21.166986, states[40]= 0.000955
Saving checkpoint... 
Iteration: 1586077321, states[0] = -95.307961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599169218, states[0] = -95.142487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612260259, states[0] = 2.024810, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1625351929, states[0] = -95.287707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638442594, states[0] = -93.542742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651534171, states[0] = 15.535662, states[40]= 0.006392
Saving checkpoint... 
Iteration: 1664625493, states[0] = -95.255986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677717100, states[0] = -56.671881, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1690807270, states[0] = 25.252221, states[40]= 0.094788
Saving checkpoint... 
Iteration: 1703898439, states[0] = -95.211223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716990096, states[0] = -25.800405, states[40]= 0.000675
Saving checkpoint... 
Iteration: 1730080330, states[0] = -95.314762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743183098, states[0] = -95.179194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756297466, states[0] = -33.751473, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1769410911, states[0] = 23.215303, states[40]= 0.043056
Saving checkpoint... 
Iteration: 1782524104, states[0] = -95.254233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795630343, states[0] = -75.937101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808729796, states[0] = -94.953180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821821047, states[0] = -95.037396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834929120, states[0] = -95.068937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848036583, states[0] = 16.612534, states[40]= 0.005281
Saving checkpoint... 
Iteration: 1861144699, states[0] = -64.148512, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1874253048, states[0] = -94.947942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887341721, states[0] = -95.018926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900450440, states[0] = -95.052342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913559438, states[0] = 8.301097, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1926659281, states[0] = -85.737774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939768533, states[0] = -94.959290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952880281, states[0] = -95.031128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954092722, states[0] = -11.238809, states[40]= 0.002072
Saving checkpoint... 
Iteration: 1967057898, states[0] = 8.967049, states[40]= 0.004821
Saving checkpoint... 
Iteration: 1980159662, states[0] = -86.203293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993263041, states[0] = -94.952308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006365472, states[0] = -95.024811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019476135, states[0] = -95.053131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032579640, states[0] = -1.482783, states[40]= 0.004002
Saving checkpoint... 
Iteration: 2045681866, states[0] = -94.803611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058785171, states[0] = -94.974558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071889207, states[0] = -95.033392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084991676, states[0] = -95.055115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098095811, states[0] = -13.968840, states[40]= 0.001604
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.931987
 - CaMKt in component CaMK (millimolar): 0.007115
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.581769
 - nass in component intracellular_ions (millimolar): 6.581829
 - ki in component intracellular_ions (millimolar): 145.393987
 - kss in component intracellular_ions (millimolar): 145.393968
 - cansr in component intracellular_ions (millimolar): 1.318319
 - cajsr in component intracellular_ions (millimolar): 1.279961
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880523
 - hs in component INa (dimensionless): 0.880518
 - j in component INa (dimensionless): 0.880489
 - hsp in component INa (dimensionless): 0.726814
 - jp in component INa (dimensionless): 0.880470
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710294
 - hLp in component INaL (dimensionless): 0.451674
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619401
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694004
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933939
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001624
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329299
 - xs1 in component IKs (dimensionless): 0.245174
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:36:42 (3344): called boinc_finish(0)

</stderr_txt>
]]>


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