𝕏

Task 55963633

Name HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378_1
Workunit 26576908
Created 3 Jul 2024, 18:18:24 UTC
Sent 3 Jul 2024, 19:39:01 UTC
Report deadline 6 Jul 2024, 19:39:01 UTC
Received 3 Jul 2024, 23:05:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237332
Run time 2 hours 28 min 54 sec
CPU time 2 hours 21 min 12 sec
Validate state Valid
Credit 49.36
Device peak FLOPS 4.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.68 MB
Peak swap size 32.63 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378_1_r144841008_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378_1_r144841008_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.904324
     * GNaL_b in INaL: 0.005914
     * Gto_b in Ito: 0.082507
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031445
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.162628
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.047554
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030298
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13713917, states[0] = 14.018177, states[40]= 0.000301
Saving checkpoint... 
Iteration: 26908207, states[0] = -12.875422, states[40]= 0.000616
Saving checkpoint... 
Iteration: 40816111, states[0] = -84.832406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53942122, states[0] = -64.018416, states[40]= 0.000024
Saving checkpoint... 
Iteration: 66769157, states[0] = -57.635182, states[40]= 0.000047
Saving checkpoint... 
Iteration: 79627049, states[0] = -84.315320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93858727, states[0] = 22.126832, states[40]= 0.000010
Saving checkpoint... 
Iteration: 108550712, states[0] = 3.588169, states[40]= 0.000148
Saving checkpoint... 
Iteration: 122602204, states[0] = -66.172230, states[40]= 0.000017
Saving checkpoint... 
Iteration: 137064312, states[0] = -16.604247, states[40]= 0.000278
Saving checkpoint... 
Iteration: 151246879, states[0] = -40.404714, states[40]= 0.000203
Saving checkpoint... 
Iteration: 165815688, states[0] = -85.026842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180262123, states[0] = -64.847354, states[40]= 0.000019
Saving checkpoint... 
Iteration: 194781858, states[0] = -84.335217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209830894, states[0] = 29.093446, states[40]= 0.002848
Saving checkpoint... 
Iteration: 224202687, states[0] = 6.205091, states[40]= 0.000094
Saving checkpoint... 
Iteration: 238764923, states[0] = -77.572848, states[40]= 0.000003
Saving checkpoint... 
Iteration: 253481112, states[0] = 28.249028, states[40]= 0.247605
Saving checkpoint... 
Iteration: 267838749, states[0] = 23.466262, states[40]= 0.000022
Saving checkpoint... 
Iteration: 281754010, states[0] = -67.903581, states[40]= 0.000013
Saving checkpoint... 
Iteration: 296330254, states[0] = 26.261114, states[40]= 0.000158
Saving checkpoint... 
Iteration: 310656877, states[0] = 28.345848, states[40]= 0.001053
Saving checkpoint... 
Iteration: 324978118, states[0] = 29.131763, states[40]= 0.053554
Saving checkpoint... 
Iteration: 339144436, states[0] = 29.346420, states[40]= 0.035952
Saving checkpoint... 
Iteration: 354043591, states[0] = -18.071104, states[40]= 0.000266
Saving checkpoint... 
Iteration: 368211044, states[0] = -21.229670, states[40]= 0.000260
Saving checkpoint... 
Iteration: 382998797, states[0] = 20.749675, states[40]= 0.000006
Saving checkpoint... 
Iteration: 397918613, states[0] = -80.696496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 412039463, states[0] = -20.468359, states[40]= 0.000260
Saving checkpoint... 
Iteration: 426469005, states[0] = 29.342819, states[40]= 0.036367
Saving checkpoint... 
Iteration: 441318923, states[0] = 24.749412, states[40]= 0.000051
Saving checkpoint... 
Iteration: 455436523, states[0] = -84.810640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470863373, states[0] = -15.351118, states[40]= 0.000284
Saving checkpoint... 
Iteration: 485344728, states[0] = 4.957065, states[40]= 0.000116
Saving checkpoint... 
Iteration: 500257970, states[0] = -84.666762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514746454, states[0] = -83.781878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528857686, states[0] = -15.505116, states[40]= 0.000281
Saving checkpoint... 
Iteration: 543615317, states[0] = 32.476740, states[40]= 0.830824
Saving checkpoint... 
Iteration: 557874099, states[0] = -42.006393, states[40]= 0.000181
Saving checkpoint... 
Iteration: 572323002, states[0] = 14.687906, states[40]= 0.000014
Saving checkpoint... 
Iteration: 586948565, states[0] = 28.304221, states[40]= 0.184952
Saving checkpoint... 
Iteration: 602105113, states[0] = -84.997884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616620577, states[0] = 29.539703, states[40]= 0.008468
Saving checkpoint... 
Iteration: 630901913, states[0] = -83.862828, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378_1_r144841008_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Schmidt_333-conf_378_1_r144841008_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.904324
     * GNaL_b in INaL: 0.005914
     * Gto_b in Ito: 0.082507
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031445
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.162628
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.047554
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030298
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 630901913
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -83.862828 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 646038906, states[0] = -51.084187, states[40]= 0.000084
Saving checkpoint... 
Iteration: 661400946, states[0] = -84.198465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676432076, states[0] = -85.003648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 690853075, states[0] = -31.761402, states[40]= 0.000285
Saving checkpoint... 
Iteration: 706010105, states[0] = -20.505694, states[40]= 0.000260
Saving checkpoint... 
Iteration: 720751383, states[0] = -84.898116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735621146, states[0] = 25.578220, states[40]= 0.000093
Saving checkpoint... 
Iteration: 749916395, states[0] = -84.910869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764908458, states[0] = -84.831219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780186743, states[0] = -43.998212, states[40]= 0.000156
Saving checkpoint... 
Iteration: 795068813, states[0] = -84.783251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809843723, states[0] = -35.162947, states[40]= 0.000262
Saving checkpoint... 
Iteration: 824328778, states[0] = -16.420064, states[40]= 0.000276
Saving checkpoint... 
Iteration: 839038900, states[0] = -78.296486, states[40]= 0.000003
Saving checkpoint... 
Iteration: 853705645, states[0] = -79.963645, states[40]= 0.000002
Saving checkpoint... 
Iteration: 868435223, states[0] = 28.090152, states[40]= 0.000789
Saving checkpoint... 
Iteration: 883257209, states[0] = 29.435561, states[40]= 0.029554
Saving checkpoint... 
Iteration: 897183430, states[0] = -54.999564, states[40]= 0.000057
Saving checkpoint... 
Iteration: 911537426, states[0] = -82.874127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925630459, states[0] = 7.901582, states[40]= 0.000069
Saving checkpoint... 
Iteration: 940423430, states[0] = 29.315542, states[40]= 0.004200
Saving checkpoint... 
Iteration: 954758987, states[0] = 28.404273, states[40]= 0.001107
Saving checkpoint... 
Iteration: 969606057, states[0] = 21.188879, states[40]= 0.000006
Saving checkpoint... 
Iteration: 984551839, states[0] = -84.799663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998890980, states[0] = -84.889467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013402396, states[0] = 30.647491, states[40]= 0.645576
Saving checkpoint... 
Iteration: 1027565411, states[0] = 34.965133, states[40]= 1.172027
Saving checkpoint... 
Iteration: 1041897951, states[0] = 34.532744, states[40]= 1.106617
Saving checkpoint... 
Iteration: 1056379448, states[0] = -84.814597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071566055, states[0] = 28.244998, states[40]= 0.239191
Saving checkpoint... 
Iteration: 1086094698, states[0] = 21.023611, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1100750289, states[0] = 26.060617, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1114945379, states[0] = 7.497352, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1129867629, states[0] = -84.746709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144181709, states[0] = -83.199389, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158694618, states[0] = -84.682989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173217097, states[0] = 33.711131, states[40]= 0.772372
Saving checkpoint... 
Iteration: 1187930243, states[0] = 13.261610, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1203019681, states[0] = -84.580012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217303666, states[0] = -36.056709, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1231751231, states[0] = 18.403913, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1246185024, states[0] = -84.659330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260824336, states[0] = -70.131890, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1275858717, states[0] = -84.816883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290728800, states[0] = 27.154704, states[40]= 0.000323
Saving checkpoint... 
Iteration: 1305366224, states[0] = -84.934898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320205669, states[0] = 29.508355, states[40]= 0.519525
Saving checkpoint... 
Iteration: 1335023178, states[0] = -84.858590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349788875, states[0] = -33.994590, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1364225482, states[0] = 25.333405, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1379478305, states[0] = -68.852850, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1394184871, states[0] = -84.865947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409131469, states[0] = -53.931228, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1423383958, states[0] = 26.399801, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1437987038, states[0] = -83.594509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453165874, states[0] = -84.678201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1467752351, states[0] = -0.556646, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1482711713, states[0] = 26.240943, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1497404280, states[0] = 9.704171, states[40]= 0.000048
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.830986
 - CaMKt in component CaMK (millimolar): 0.217838
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.282078
 - nass in component intracellular_ions (millimolar): 7.282432
 - ki in component intracellular_ions (millimolar): 143.831221
 - kss in component intracellular_ions (millimolar): 143.831187
 - cansr in component intracellular_ions (millimolar): 3.343274
 - cajsr in component intracellular_ions (millimolar): 1.927106
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009973
 - hf in component INa (dimensionless): 0.583614
 - hs in component INa (dimensionless): 0.582550
 - j in component INa (dimensionless): 0.551561
 - hsp in component INa (dimensionless): 0.330896
 - jp in component INa (dimensionless): 0.508822
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.180429
 - hLp in component INaL (dimensionless): 0.073376
 - a in component Ito (dimensionless): 0.001230
 - iF in component Ito (dimensionless): 0.999235
 - iS in component Ito (dimensionless): 0.129938
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999236
 - iSp in component Ito (dimensionless): 0.145049
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.675670
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.927888
 - jca in component ICaL (dimensionless): 0.910477
 - ffp in component ICaL (dimensionless): 0.998854
 - fcafp in component ICaL (dimensionless): 0.999937
 - nca in component ICaL (dimensionless): 0.042403
 - xrf in component IKr (dimensionless): 0.103785
 - xrs in component IKr (dimensionless): 0.874129
 - xs1 in component IKs (dimensionless): 0.571884
 - xs2 in component IKs (dimensionless): 0.007547
 - xk1 in component IK1 (dimensionless): 0.996741
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:19:00 (68714): called boinc_finish(0)

</stderr_txt>
]]>


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