𝕏

Task 55961908

Name HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_114_1
Workunit 26576047
Created 3 Jul 2024, 18:17:22 UTC
Sent 3 Jul 2024, 19:28:51 UTC
Report deadline 7 Jul 2024, 5:04:51 UTC
Received 6 Jul 2024, 12:01:59 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 197686
Run time 3 hours 7 min 24 sec
CPU time 5 min 49 sec
Validate state Valid
Credit 62.19
Device peak FLOPS 3.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.75 MB
Peak swap size 1.54 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_114.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_114_1_r646735308_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_114_1_r646735308_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.187108
     * GNaL_b in INaL: 0.005631
     * Gto_b in Ito: 0.081299
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031710
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.167785
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.706006
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030134
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11928390, states[0] = -95.118386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23890647, states[0] = -95.077334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35898584, states[0] = -95.061354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48006430, states[0] = 25.878703, states[40]= 0.117881
Saving checkpoint... 
Iteration: 60130718, states[0] = -51.453276, states[40]= 0.000022
Saving checkpoint... 
Iteration: 72188359, states[0] = -94.834326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84279333, states[0] = -94.967549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96360038, states[0] = -95.016631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108685221, states[0] = -94.818551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120999929, states[0] = -95.046471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133344569, states[0] = -95.005658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145678475, states[0] = -94.788763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157995182, states[0] = -95.044008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170348305, states[0] = -95.006113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182663003, states[0] = -92.766205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194982847, states[0] = -95.041789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207225668, states[0] = -94.892567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219558237, states[0] = 8.203927, states[40]= 0.004897
Saving checkpoint... 
Iteration: 231726708, states[0] = -94.894091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243704509, states[0] = -94.855052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255775784, states[0] = -94.955588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267861721, states[0] = -95.011362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279952212, states[0] = -95.036681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291986368, states[0] = -95.041887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304021825, states[0] = 21.000951, states[40]= 0.008459
Saving checkpoint... 
Iteration: 316036836, states[0] = 16.508725, states[40]= 0.005467
Saving checkpoint... 
Iteration: 328024217, states[0] = 20.415964, states[40]= 0.007403
Saving checkpoint... 
Iteration: 340099389, states[0] = -19.313166, states[40]= 0.001020
Saving checkpoint... 
Iteration: 352184211, states[0] = -94.811355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364322951, states[0] = -94.991768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376422410, states[0] = -95.030464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388509765, states[0] = 23.564856, states[40]= 0.055193
Saving checkpoint... 
Iteration: 400682247, states[0] = -94.805127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413044574, states[0] = 13.664526, states[40]= 0.005129
Saving checkpoint... 
Iteration: 425381214, states[0] = -95.018616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437686840, states[0] = -94.818144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449991429, states[0] = -95.042409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462308242, states[0] = -94.982156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474647087, states[0] = -69.491061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486977809, states[0] = -95.040588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499203243, states[0] = -94.852364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511323084, states[0] = -94.991752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523497444, states[0] = -95.043084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535593981, states[0] = -14.218028, states[40]= 0.001585
Saving checkpoint... 
Iteration: 547778589, states[0] = -94.958021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559901644, states[0] = -95.024954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572040799, states[0] = 15.080223, states[40]= 0.005258
Saving checkpoint... 
Iteration: 584152327, states[0] = -77.677066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596379370, states[0] = -95.017864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608595694, states[0] = -15.819593, states[40]= 0.001365
Saving checkpoint... 
Iteration: 620813015, states[0] = -94.985305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633027245, states[0] = 19.594313, states[40]= 0.006596
Saving checkpoint... 
Iteration: 645347962, states[0] = -95.004979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657535558, states[0] = 16.954015, states[40]= 0.005556
Saving checkpoint... 
Iteration: 669770008, states[0] = -94.949515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682022956, states[0] = 20.731864, states[40]= 0.007895
Saving checkpoint... 
Iteration: 694188566, states[0] = -94.822010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706286572, states[0] = -94.965125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718352889, states[0] = -95.007211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730552958, states[0] = 10.384512, states[40]= 0.004971
Saving checkpoint... 
Iteration: 742788768, states[0] = -94.966984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755096289, states[0] = -16.379596, states[40]= 0.001298
Saving checkpoint... 
Iteration: 767412873, states[0] = -95.027866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779706719, states[0] = -94.858841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791971727, states[0] = -95.039514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804304462, states[0] = -94.979251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816666564, states[0] = -94.091721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828956016, states[0] = -95.036972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841207173, states[0] = -94.859658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853408726, states[0] = -95.026723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865658099, states[0] = -87.627027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877927379, states[0] = -95.031286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890249254, states[0] = -94.925654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902643384, states[0] = -64.577840, states[40]= 0.000002
Saving checkpoint... 
Iteration: 914944212, states[0] = -95.034766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927259976, states[0] = -94.938513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939581046, states[0] = -3.599050, states[40]= 0.003686
Saving checkpoint... 
Iteration: 951931439, states[0] = -95.032134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964243292, states[0] = -94.917811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976536305, states[0] = 16.694948, states[40]= 0.005503
Saving checkpoint... 
Iteration: 988862742, states[0] = -95.011286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001464415, states[0] = -95.038254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014128073, states[0] = -47.289966, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1026706297, states[0] = -94.857883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039377465, states[0] = -95.016906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052015722, states[0] = 22.236705, states[40]= 0.016376
Saving checkpoint... 
Iteration: 1064446647, states[0] = -95.035134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077091840, states[0] = -12.251220, states[40]= 0.001910
Saving checkpoint... 
Iteration: 1089742580, states[0] = -94.916767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102337994, states[0] = -94.999735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114898712, states[0] = -95.023752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127521662, states[0] = 21.038954, states[40]= 0.008552
Saving checkpoint... 
Iteration: 1140082739, states[0] = -4.782557, states[40]= 0.003453
Saving checkpoint... 
Iteration: 1152654508, states[0] = -81.523353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165365951, states[0] = -95.012473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178009059, states[0] = 23.861537, states[40]= 0.065132
Saving checkpoint... 
Iteration: 1190618314, states[0] = -37.367439, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1203155084, states[0] = -82.553191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215887442, states[0] = -95.020201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228568808, states[0] = 3.412841, states[40]= 0.004632
Saving checkpoint... 
Iteration: 1241225330, states[0] = -94.891129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253861660, states[0] = -95.010670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266636255, states[0] = -56.197034, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1279013296, states[0] = 22.674410, states[40]= 0.025333
Saving checkpoint... 
Iteration: 1291615752, states[0] = -34.878196, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1304181580, states[0] = -94.802081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316624949, states[0] = -44.023523, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1329187794, states[0] = -94.819829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341740101, states[0] = -94.913199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354445125, states[0] = -95.034661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367198596, states[0] = -94.842644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379662909, states[0] = -92.685814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392326989, states[0] = -94.993497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404976020, states[0] = -95.039750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417417738, states[0] = -95.028675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429681690, states[0] = -94.802422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441999313, states[0] = -95.042715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454352882, states[0] = -95.006738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466570813, states[0] = 2.405069, states[40]= 0.004544
Saving checkpoint... 
Iteration: 1478877732, states[0] = -95.016721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491206699, states[0] = -94.858346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503537332, states[0] = -95.204759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515684521, states[0] = -19.006865, states[40]= 0.001130
Saving checkpoint... 
Iteration: 1527921148, states[0] = 20.894985, states[40]= 0.010269
Saving checkpoint... 
Iteration: 1540118533, states[0] = -95.212169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552350826, states[0] = -94.994027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564677216, states[0] = -95.144687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577019202, states[0] = -95.226838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589232502, states[0] = -82.509814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601522457, states[0] = -65.725664, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1613792247, states[0] = -29.655865, states[40]= 0.000476
Saving checkpoint... 
Iteration: 1626041615, states[0] = 11.825068, states[40]= 0.006012
Saving checkpoint... 
Iteration: 1638255985, states[0] = -95.276893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650238336, states[0] = -95.257890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662523064, states[0] = -95.238075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674837143, states[0] = -95.256734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687169741, states[0] = -95.290139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699380342, states[0] = -95.160719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711595879, states[0] = -33.727980, states[40]= 0.000304
Saving checkpoint... 
Iteration: 1723887719, states[0] = -24.803535, states[40]= 0.000723
Saving checkpoint... 
Iteration: 1736185510, states[0] = -22.384785, states[40]= 0.000869
Saving checkpoint... 
Iteration: 1748385638, states[0] = -95.302682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760606318, states[0] = -95.212152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772862871, states[0] = -95.116921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785045127, states[0] = 10.019810, states[40]= 0.005827
Saving checkpoint... 
Iteration: 1797353295, states[0] = 5.578699, states[40]= 0.005452
Saving checkpoint... 
Iteration: 1809623168, states[0] = -45.776151, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1821833442, states[0] = -95.030953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834047033, states[0] = 12.311231, states[40]= 0.005076
Saving checkpoint... 
Iteration: 1846299040, states[0] = -94.991513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858554783, states[0] = 9.416549, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1870764055, states[0] = -94.950704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883085353, states[0] = -7.001096, states[40]= 0.002989
Saving checkpoint... 
Iteration: 1895431474, states[0] = -95.035429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907340696, states[0] = -95.003343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918730689, states[0] = -94.901076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930077948, states[0] = -1.641853, states[40]= 0.004031
Saving checkpoint... 
Iteration: 1941332755, states[0] = -94.997369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952681731, states[0] = -94.803010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964154922, states[0] = -82.335633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975699066, states[0] = -94.843517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987436038, states[0] = -95.032657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998483295, states[0] = -95.040512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010159338, states[0] = -89.371324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022110328, states[0] = -29.688771, states[40]= 0.000483
Saving checkpoint... 
Iteration: 2034114691, states[0] = -33.859546, states[40]= 0.000302
Saving checkpoint... 
Iteration: 2045904158, states[0] = -95.024707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057840291, states[0] = -95.000286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069818913, states[0] = -94.988159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081876469, states[0] = -95.015843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093797127, states[0] = -94.972871, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.918204
 - CaMKt in component CaMK (millimolar): 0.006972
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.567955
 - nass in component intracellular_ions (millimolar): 6.568015
 - ki in component intracellular_ions (millimolar): 145.409366
 - kss in component intracellular_ions (millimolar): 145.409347
 - cansr in component intracellular_ions (millimolar): 1.313100
 - cajsr in component intracellular_ions (millimolar): 1.275193
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003613
 - hf in component INa (dimensionless): 0.880284
 - hs in component INa (dimensionless): 0.880280
 - j in component INa (dimensionless): 0.880251
 - hsp in component INa (dimensionless): 0.726365
 - jp in component INa (dimensionless): 0.880232
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710541
 - hLp in component INaL (dimensionless): 0.453080
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621980
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696993
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935358
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001609
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330169
 - xs1 in component IKs (dimensionless): 0.240641
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:01:45 (10520): called boinc_finish(0)

</stderr_txt>
]]>


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