𝕏

Task 55953014

Name HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_907_0
Workunit 26571665
Created 3 Jul 2024, 17:30:52 UTC
Sent 3 Jul 2024, 18:33:57 UTC
Report deadline 7 Jul 2024, 4:09:57 UTC
Received 5 Jul 2024, 4:18:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224229
Run time 2 hours 25 min
CPU time 2 hours 8 min 39 sec
Validate state Valid
Credit 63.87
Device peak FLOPS 5.85 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.13 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_907.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_907_0_r1796873439_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_907_0_r1796873439_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.715552
     * GNaL_b in INaL: 0.006014
     * Gto_b in Ito: 0.082423
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031896
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.166759
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.261624
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030467
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15906399, states[0] = -95.092459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31597603, states[0] = -19.135465, states[40]= 0.001037
Saving checkpoint... 
Iteration: 47237283, states[0] = -94.928955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63017509, states[0] = 21.811756, states[40]= 0.012620
Saving checkpoint... 
Iteration: 78657763, states[0] = -86.951009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93989427, states[0] = -95.043605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109042307, states[0] = 14.636363, states[40]= 0.005187
Saving checkpoint... 
Iteration: 123353391, states[0] = -95.005170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138498787, states[0] = -95.040306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154634670, states[0] = -53.574088, states[40]= 0.000016
Saving checkpoint... 
Iteration: 172377527, states[0] = -95.013006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192458205, states[0] = -95.033229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211343780, states[0] = -94.998187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226700638, states[0] = -94.840439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242152591, states[0] = -76.737408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257090101, states[0] = -10.068470, states[40]= 0.002326
Saving checkpoint... 
Iteration: 271430752, states[0] = -95.027543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284765009, states[0] = -94.938540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299045824, states[0] = 13.378864, states[40]= 0.005085
Saving checkpoint... 
Iteration: 313827385, states[0] = -94.989078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329105179, states[0] = -24.026457, states[40]= 0.000758
Saving checkpoint... 
Iteration: 343868895, states[0] = -95.009048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357857224, states[0] = -95.004195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372375259, states[0] = -95.011452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386983995, states[0] = -95.036681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401362840, states[0] = -95.006563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415948649, states[0] = -95.031050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430325787, states[0] = -94.988052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445118665, states[0] = -36.848511, states[40]= 0.000206
Saving checkpoint... 
Iteration: 460692855, states[0] = -94.824185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475720390, states[0] = -94.876735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490793946, states[0] = -94.965788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505369095, states[0] = -95.009019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520185401, states[0] = -94.806598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534851901, states[0] = -95.001685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549491025, states[0] = -95.037487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563798191, states[0] = -94.969127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579339157, states[0] = -94.995402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597012931, states[0] = 22.746789, states[40]= 0.027391
Saving checkpoint... 
Iteration: 611861750, states[0] = -95.005972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626202040, states[0] = -94.842838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640489899, states[0] = -95.037287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654275982, states[0] = -94.949632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668590871, states[0] = -10.735220, states[40]= 0.002192
Saving checkpoint... 
Iteration: 682117587, states[0] = -35.803121, states[40]= 0.000237
Saving checkpoint... 
Iteration: 697610684, states[0] = -29.215341, states[40]= 0.000512
Saving checkpoint... 
Iteration: 711609551, states[0] = -28.144505, states[40]= 0.000564
Saving checkpoint... 
Iteration: 725495789, states[0] = -95.037957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740336215, states[0] = -94.993742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755292439, states[0] = -94.964381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770687461, states[0] = -94.811820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788374142, states[0] = -95.010769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807586193, states[0] = -6.849241, states[40]= 0.003012
Saving checkpoint... 
Iteration: 825560629, states[0] = 7.443367, states[40]= 0.004858
Saving checkpoint... 
Iteration: 841098894, states[0] = -18.110001, states[40]= 0.001120
Saving checkpoint... 
Iteration: 856796451, states[0] = -94.967569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873636419, states[0] = -55.438279, states[40]= 0.000012
Saving checkpoint... 
Iteration: 889352497, states[0] = -95.001732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905408309, states[0] = -95.021611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921045464, states[0] = 13.515578, states[40]= 0.005093
Saving checkpoint... 
Iteration: 936221982, states[0] = -94.879132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951386923, states[0] = -95.015162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965653598, states[0] = -78.448957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979339344, states[0] = -94.995243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993684866, states[0] = -94.804757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008314506, states[0] = -94.980596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022826985, states[0] = -94.988380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036935084, states[0] = -95.027956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050374165, states[0] = -95.010610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065594998, states[0] = -14.465791, states[40]= 0.001546
Saving checkpoint... 
Iteration: 1080820089, states[0] = -94.984154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095775180, states[0] = -94.948561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110757902, states[0] = -94.929925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125891456, states[0] = -95.016520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141579555, states[0] = -2.176355, states[40]= 0.003935
Saving checkpoint... 
Iteration: 1155366382, states[0] = -95.007527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169414553, states[0] = -95.023087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181819178, states[0] = -94.983515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195399360, states[0] = -95.018894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209482020, states[0] = -95.035888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223621447, states[0] = -39.580350, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1237412814, states[0] = -95.022595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251641379, states[0] = -61.135219, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1267314975, states[0] = -94.980740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281604289, states[0] = -23.188410, states[40]= 0.000798
Saving checkpoint... 
Iteration: 1295584529, states[0] = -5.583351, states[40]= 0.003282
Saving checkpoint... 
Iteration: 1309390752, states[0] = -95.016178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322937030, states[0] = -95.028181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336733403, states[0] = -94.897059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349981766, states[0] = -95.035763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363284219, states[0] = -94.956901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376565487, states[0] = 5.290616, states[40]= 0.004753
Saving checkpoint... 
Iteration: 1388832553, states[0] = -94.991327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401392653, states[0] = -95.016721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414098253, states[0] = -17.506761, states[40]= 0.001177
Saving checkpoint... 
Iteration: 1427291906, states[0] = -94.963508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438467516, states[0] = -95.033621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450575531, states[0] = 0.222805, states[40]= 0.004292
Saving checkpoint... 
Iteration: 1464285235, states[0] = -94.957744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479269896, states[0] = -94.942964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493649042, states[0] = -71.131852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1507681838, states[0] = -95.113994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521101844, states[0] = -37.462855, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1535559510, states[0] = -95.075078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549711807, states[0] = -95.203270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564086913, states[0] = -95.162031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578698542, states[0] = -35.638001, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1592477966, states[0] = -13.413827, states[40]= 0.001932
Saving checkpoint... 
Iteration: 1606698542, states[0] = -95.192457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620820626, states[0] = -95.230357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635400592, states[0] = -38.184588, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1650814679, states[0] = -95.222157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665460543, states[0] = -95.104120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680006137, states[0] = 27.570638, states[40]= 0.113693
Saving checkpoint... 
Iteration: 1694668040, states[0] = -95.286209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709073754, states[0] = -95.291109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723128892, states[0] = -95.243385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736694022, states[0] = -95.306174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750259931, states[0] = 1.798317, states[40]= 0.005060
Saving checkpoint... 
Iteration: 1764131777, states[0] = -80.445249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777613487, states[0] = -53.433583, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1790708789, states[0] = 24.823647, states[40]= 0.068481
Saving checkpoint... 
Iteration: 1803569523, states[0] = 1.686316, states[40]= 0.004615
Saving checkpoint... 
Iteration: 1816626998, states[0] = -48.293497, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1830186824, states[0] = -94.837248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843917379, states[0] = -95.041804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856834962, states[0] = -95.004948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869925503, states[0] = -95.033792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883373202, states[0] = -95.015404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897042535, states[0] = 14.552734, states[40]= 0.005179
Saving checkpoint... 
Iteration: 1911154435, states[0] = -80.261827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925493971, states[0] = -95.038569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939520344, states[0] = 21.380374, states[40]= 0.009433
Saving checkpoint... 
Iteration: 1953322084, states[0] = -94.985514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967377968, states[0] = -95.011845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981596901, states[0] = -16.256104, states[40]= 0.001311
Saving checkpoint... 
Iteration: 1995533743, states[0] = 17.702417, states[40]= 0.005688
Saving checkpoint... 
Iteration: 2009637147, states[0] = -56.266000, states[40]= 0.000010
Saving checkpoint... 
Iteration: 2024405590, states[0] = -95.020182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039648631, states[0] = -70.537992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2054615505, states[0] = -33.801930, states[40]= 0.000307
Saving checkpoint... 
Iteration: 2069392985, states[0] = -95.016366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083731941, states[0] = -94.894319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097559568, states[0] = 7.896131, states[40]= 0.004875
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.913402
 - CaMKt in component CaMK (millimolar): 0.007006
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.589867
 - nass in component intracellular_ions (millimolar): 6.589928
 - ki in component intracellular_ions (millimolar): 145.387169
 - kss in component intracellular_ions (millimolar): 145.387150
 - cansr in component intracellular_ions (millimolar): 1.314369
 - cajsr in component intracellular_ions (millimolar): 1.276330
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880201
 - hs in component INa (dimensionless): 0.880196
 - j in component INa (dimensionless): 0.880168
 - hsp in component INa (dimensionless): 0.726208
 - jp in component INa (dimensionless): 0.880149
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710215
 - hLp in component INaL (dimensionless): 0.452339
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621032
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695824
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934623
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332278
 - xs1 in component IKs (dimensionless): 0.242383
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:41:54 (943936): called boinc_finish(0)

</stderr_txt>
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