𝕏

Task 55952921

Name HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203_1
Workunit 26571618
Created 3 Jul 2024, 17:30:51 UTC
Sent 3 Jul 2024, 18:33:28 UTC
Report deadline 7 Jul 2024, 4:09:28 UTC
Received 3 Jul 2024, 23:05:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237332
Run time 3 hours 28 min 18 sec
CPU time 3 hours 16 min 38 sec
Validate state Valid
Credit 61.92
Device peak FLOPS 4.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 32.63 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r834015200_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r834015200_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.389440
     * GNaL_b in INaL: 0.005830
     * Gto_b in Ito: 0.083225
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032266
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.167895
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.280199
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032052
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14684833, states[0] = -94.889824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29260138, states[0] = -94.976062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43983069, states[0] = -95.059377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57687115, states[0] = -94.831110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72323707, states[0] = -94.995572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86783877, states[0] = -94.962792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101157028, states[0] = -88.228814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115339459, states[0] = -94.996026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129743892, states[0] = -94.914067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143978594, states[0] = -95.033443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158028739, states[0] = 18.990472, states[40]= 0.006330
Saving checkpoint... 
Iteration: 172412408, states[0] = -95.020093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186411814, states[0] = -95.019737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200922877, states[0] = -95.022284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215004356, states[0] = 30.615444, states[40]= 0.153271
Saving checkpoint... 
Iteration: 229430713, states[0] = -95.023869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243937530, states[0] = -95.025240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258014387, states[0] = 22.273937, states[40]= 0.020784
Saving checkpoint... 
Iteration: 272202053, states[0] = -94.843834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286865412, states[0] = -95.004448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301658638, states[0] = -89.869339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315959027, states[0] = -95.029057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330517376, states[0] = 21.743548, states[40]= 0.013018
Saving checkpoint... 
Iteration: 344898525, states[0] = -95.015638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359599727, states[0] = -20.200857, states[40]= 0.000953
Saving checkpoint... 
Iteration: 373951055, states[0] = -95.027649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388448146, states[0] = -95.027116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402623869, states[0] = -43.765052, states[40]= 0.000073
Saving checkpoint... 
Iteration: 416820732, states[0] = -94.982295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430989547, states[0] = -95.033351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445649691, states[0] = -75.086260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460387259, states[0] = -95.012122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474426429, states[0] = -95.022668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488484903, states[0] = -95.032728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502921284, states[0] = -95.021473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517220407, states[0] = -94.876747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531746179, states[0] = -94.914720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546377154, states[0] = -95.008657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561098837, states[0] = -19.349629, states[40]= 0.001014
Saving checkpoint... 
Iteration: 575582506, states[0] = -4.951586, states[40]= 0.003418
Saving checkpoint... 
Iteration: 590038365, states[0] = 15.822164, states[40]= 0.005373
Saving checkpoint... 
Iteration: 604553845, states[0] = 9.875737, states[40]= 0.004948
Saving checkpoint... 
Iteration: 618758198, states[0] = -94.929284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633309074, states[0] = -94.974643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647411066, states[0] = -95.018871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661100553, states[0] = -20.990227, states[40]= 0.000903
Saving checkpoint... 
Iteration: 674830845, states[0] = -94.987988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688256522, states[0] = -94.927308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701490724, states[0] = -95.033326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714921201, states[0] = -95.021320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728497866, states[0] = -95.034152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743944559, states[0] = -95.026225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758993614, states[0] = -95.033638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773771662, states[0] = -94.943560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788888022, states[0] = -95.012159, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r834015200_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703193045190825_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r834015200_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.389440
     * GNaL_b in INaL: 0.005830
     * Gto_b in Ito: 0.083225
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032266
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.167895
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.280199
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032052
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 788888022
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.012159 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 803475142, states[0] = -95.031208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818155755, states[0] = -85.649804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833309680, states[0] = -94.974929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847647292, states[0] = -71.342385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862157780, states[0] = -88.762903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876221833, states[0] = -94.878878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891282003, states[0] = -94.953257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906611248, states[0] = -31.228997, states[40]= 0.000406
Saving checkpoint... 
Iteration: 921917414, states[0] = -95.020286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936673382, states[0] = -94.730943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951835683, states[0] = -94.990417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966658035, states[0] = -89.105849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981745497, states[0] = -94.913551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996287304, states[0] = -94.957814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010968970, states[0] = -95.030176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025147787, states[0] = -72.085633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1040046862, states[0] = 12.644634, states[40]= 0.005064
Saving checkpoint... 
Iteration: 1055032897, states[0] = 17.702089, states[40]= 0.005788
Saving checkpoint... 
Iteration: 1069989030, states[0] = -95.032885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085053697, states[0] = 9.936109, states[40]= 0.004950
Saving checkpoint... 
Iteration: 1099909796, states[0] = -95.018257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114491973, states[0] = -95.033217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129173175, states[0] = -94.726671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144688308, states[0] = -94.815163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159236615, states[0] = -94.901343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174195140, states[0] = -94.829515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189230508, states[0] = -94.892361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204285409, states[0] = -94.956058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219387036, states[0] = -95.011571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233999170, states[0] = -95.033982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248154194, states[0] = -82.933005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262830340, states[0] = -94.987338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277163821, states[0] = -93.631207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291860994, states[0] = -95.002010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306306206, states[0] = -94.972233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320891370, states[0] = -95.012877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335968539, states[0] = -95.029907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350587636, states[0] = -9.004075, states[40]= 0.002553
Saving checkpoint... 
Iteration: 1365684433, states[0] = -94.805882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380250067, states[0] = -94.919110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394703707, states[0] = -94.846274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409875395, states[0] = -95.007485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424158074, states[0] = -89.156259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438669256, states[0] = -94.572526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453780825, states[0] = -94.951839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468293970, states[0] = -94.962990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483130211, states[0] = -50.547982, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1497606166, states[0] = -26.352880, states[40]= 0.000636
Saving checkpoint... 
Iteration: 1511923478, states[0] = -95.188324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526528475, states[0] = -73.916564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1541041073, states[0] = -95.235710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555640951, states[0] = -93.649182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570368890, states[0] = -95.120724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584681961, states[0] = -18.852860, states[40]= 0.001156
Saving checkpoint... 
Iteration: 1599130001, states[0] = -79.747689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613720970, states[0] = 20.509471, states[40]= 0.010347
Saving checkpoint... 
Iteration: 1628405762, states[0] = 28.128269, states[40]= 0.119244
Saving checkpoint... 
Iteration: 1642669669, states[0] = -95.129500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657197288, states[0] = -95.302829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671547931, states[0] = -95.262214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686172955, states[0] = -95.138043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700798875, states[0] = -37.801980, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1715364356, states[0] = -95.278418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730197686, states[0] = -36.472865, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1744938325, states[0] = -92.577371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759947021, states[0] = -94.920352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774534437, states[0] = 15.087147, states[40]= 0.006560
Saving checkpoint... 
Iteration: 1788873437, states[0] = -95.286127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803221339, states[0] = -94.926867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817827296, states[0] = -95.023631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832446308, states[0] = -95.051448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847127818, states[0] = -49.203277, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1861524131, states[0] = 20.153019, states[40]= 0.007434
Saving checkpoint... 
Iteration: 1876372871, states[0] = -95.013195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891280066, states[0] = -94.955349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905631331, states[0] = -52.007296, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1920336778, states[0] = -94.992228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935107220, states[0] = -27.437091, states[40]= 0.000585
Saving checkpoint... 
Iteration: 1949754859, states[0] = -94.925314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964563396, states[0] = 5.772716, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1979402362, states[0] = -95.015973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994305320, states[0] = -94.971334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008575626, states[0] = -0.461579, states[40]= 0.004205
Saving checkpoint... 
Iteration: 2023004431, states[0] = 30.351524, states[40]= 0.152890
Saving checkpoint... 
Iteration: 2037807041, states[0] = -94.972359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052526588, states[0] = 19.617997, states[40]= 0.006755
Saving checkpoint... 
Iteration: 2066844082, states[0] = -94.993924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081383346, states[0] = -95.009779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095533739, states[0] = 17.424033, states[40]= 0.005707
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909360
 - CaMKt in component CaMK (millimolar): 0.006938
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.596988
 - nass in component intracellular_ions (millimolar): 6.597048
 - ki in component intracellular_ions (millimolar): 145.380801
 - kss in component intracellular_ions (millimolar): 145.380782
 - cansr in component intracellular_ions (millimolar): 1.311291
 - cajsr in component intracellular_ions (millimolar): 1.273494
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880131
 - hs in component INa (dimensionless): 0.880127
 - j in component INa (dimensionless): 0.880099
 - hsp in component INa (dimensionless): 0.726077
 - jp in component INa (dimensionless): 0.880080
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710575
 - hLp in component INaL (dimensionless): 0.453620
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622937
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698150
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936070
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001601
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329868
 - xs1 in component IKs (dimensionless): 0.239351
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:21:51 (68364): called boinc_finish(0)

</stderr_txt>
]]>


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