𝕏

Task 55952740

Name HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126_2
Workunit 26307602
Created 3 Jul 2024, 17:18:56 UTC
Sent 3 Jul 2024, 18:31:08 UTC
Report deadline 7 Jul 2024, 4:07:08 UTC
Received 4 Jul 2024, 16:11:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224270
Run time 1 hours 38 min 47 sec
CPU time 1 hours 18 min 40 sec
Validate state Valid
Credit 64.48
Device peak FLOPS 4.95 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.24 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126_2_r1953785697_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126_2_r1953785697_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.971066
     * GNaL_b in INaL: 0.004462
     * Gto_b in Ito: 0.087945
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032285
     * GKs_b in IKs: 0.001764
     * GK1_b in IK1: 0.167196
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 68.752877
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051113
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16458325, states[0] = -95.041798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40341545, states[0] = -94.976368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64478659, states[0] = -94.997043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88323873, states[0] = -94.946380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112437023, states[0] = -94.980638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137002046, states[0] = 43.901407, states[40]= 0.087119
Saving checkpoint... 
Iteration: 161965224, states[0] = -94.982749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186908076, states[0] = -94.971578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212044400, states[0] = 12.341668, states[40]= 0.005049
Saving checkpoint... 
Iteration: 236936703, states[0] = -94.977380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262029058, states[0] = 17.768081, states[40]= 0.006229
Saving checkpoint... 
Iteration: 286922963, states[0] = -94.974555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312090704, states[0] = -14.755271, states[40]= 0.001494
Saving checkpoint... 
Iteration: 335358696, states[0] = -94.955800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359100663, states[0] = -24.514484, states[40]= 0.000685
Saving checkpoint... 
Iteration: 382461938, states[0] = -94.981387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405700202, states[0] = -94.804967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428948907, states[0] = -94.979323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451181514, states[0] = -94.767018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473469164, states[0] = -94.982354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496787154, states[0] = -94.915332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520031007, states[0] = 17.158606, states[40]= 0.005948
Saving checkpoint... 
Iteration: 543810964, states[0] = -94.932019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567842824, states[0] = -94.948977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582318166, states[0] = -94.936313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604561081, states[0] = 5.408340, states[40]= 0.004706
Saving checkpoint... 
Iteration: 627410820, states[0] = -94.971603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650859355, states[0] = -94.955857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673873933, states[0] = -94.961104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696721567, states[0] = -94.841178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712665135, states[0] = -94.465993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736297629, states[0] = -94.923036, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126_2_r1953785697_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080046859196_ORdGradInc_k_25-Pueyo_APDR-conf_126_2_r1953785697_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.971066
     * GNaL_b in INaL: 0.004462
     * Gto_b in Ito: 0.087945
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032285
     * GKs_b in IKs: 0.001764
     * GK1_b in IK1: 0.167196
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 68.752877
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051113
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 736297629
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.923036 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 753561920, states[0] = 5.023346, states[40]= 0.004684
Saving checkpoint... 
Iteration: 772422076, states[0] = -94.974049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791693893, states[0] = -94.792748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808693925, states[0] = -94.792799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829613148, states[0] = -36.847487, states[40]= 0.000185
Saving checkpoint... 
Iteration: 847320345, states[0] = -94.937396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864107013, states[0] = -30.763717, states[40]= 0.000396
Saving checkpoint... 
Iteration: 877569986, states[0] = 0.996669, states[40]= 0.004345
Saving checkpoint... 
Iteration: 897174081, states[0] = -94.737802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916542102, states[0] = 13.224775, states[40]= 0.005128
Saving checkpoint... 
Iteration: 935542219, states[0] = 13.180358, states[40]= 0.005124
Saving checkpoint... 
Iteration: 957185652, states[0] = -94.776061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980816781, states[0] = -94.935261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002567980, states[0] = 2.064094, states[40]= 0.004457
Saving checkpoint... 
Iteration: 1019068488, states[0] = 1.798685, states[40]= 0.004431
Saving checkpoint... 
Iteration: 1032133710, states[0] = -58.628556, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1050178876, states[0] = -94.759438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069314885, states[0] = -94.934085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089204478, states[0] = -94.812358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101752067, states[0] = -94.881559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119661239, states[0] = -93.812527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139076907, states[0] = -3.187292, states[40]= 0.003727
Saving checkpoint... 
Iteration: 1156945016, states[0] = -94.978219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175558950, states[0] = 6.365300, states[40]= 0.004755
Saving checkpoint... 
Iteration: 1195356112, states[0] = -94.954248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215690781, states[0] = -94.786377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234396616, states[0] = -94.967624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253845451, states[0] = -94.949732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273237199, states[0] = -94.863211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292222443, states[0] = -94.842158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312089148, states[0] = -13.265216, states[40]= 0.001723
Saving checkpoint... 
Iteration: 1326466941, states[0] = -94.981523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345931824, states[0] = -94.975685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366115732, states[0] = -39.445442, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1385278704, states[0] = -94.907809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405486623, states[0] = -94.983985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422067426, states[0] = 2.350146, states[40]= 0.004484
Saving checkpoint... 
Iteration: 1441810030, states[0] = -94.930884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459640730, states[0] = -67.081678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475968359, states[0] = -94.981628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496876283, states[0] = -94.961380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508610717, states[0] = -95.128340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526536792, states[0] = -92.127629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546712177, states[0] = -95.161006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559248282, states[0] = -94.984487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580874623, states[0] = -95.102841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599117390, states[0] = -64.291745, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1617899146, states[0] = -95.258390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636334121, states[0] = -91.390129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654609060, states[0] = -53.776720, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1674228617, states[0] = -95.199210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694877980, states[0] = -95.115453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713313340, states[0] = 21.819712, states[40]= 0.027055
Saving checkpoint... 
Iteration: 1733092896, states[0] = -95.256182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752511637, states[0] = -95.176308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769784393, states[0] = -25.033201, states[40]= 0.000675
Saving checkpoint... 
Iteration: 1788969174, states[0] = -8.136828, states[40]= 0.003059
Saving checkpoint... 
Iteration: 1807463006, states[0] = -95.030061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825290729, states[0] = -94.948702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843716828, states[0] = -94.851863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862696732, states[0] = -94.808341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880331219, states[0] = -94.948838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898518479, states[0] = 20.413064, states[40]= 0.011380
Saving checkpoint... 
Iteration: 1916568690, states[0] = 1.632503, states[40]= 0.004416
Saving checkpoint... 
Iteration: 1935253462, states[0] = -94.883844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953604703, states[0] = -28.532895, states[40]= 0.000496
Saving checkpoint... 
Iteration: 1972082963, states[0] = -7.749074, states[40]= 0.002803
Saving checkpoint... 
Iteration: 1991459182, states[0] = -94.980179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010251471, states[0] = -94.880410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028908934, states[0] = -94.970320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047729614, states[0] = -94.852299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066007866, states[0] = 23.243122, states[40]= 0.086760
Saving checkpoint... 
Iteration: 2084481321, states[0] = -94.982902, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.860846
 - CaMKt in component CaMK (millimolar): 0.006726
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.639254
 - nass in component intracellular_ions (millimolar): 6.639312
 - ki in component intracellular_ions (millimolar): 145.341639
 - kss in component intracellular_ions (millimolar): 145.341620
 - cansr in component intracellular_ions (millimolar): 1.297488
 - cajsr in component intracellular_ions (millimolar): 1.260263
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003634
 - hf in component INa (dimensionless): 0.879287
 - hs in component INa (dimensionless): 0.879283
 - j in component INa (dimensionless): 0.879258
 - hsp in component INa (dimensionless): 0.724491
 - jp in component INa (dimensionless): 0.879241
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710136
 - hLp in component INaL (dimensionless): 0.454696
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.626721
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.702969
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940822
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999902
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.319459
 - xs1 in component IKs (dimensionless): 0.230771
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:10:59 (9040): called boinc_finish(0)

</stderr_txt>
]]>