𝕏

Task 55952539

Name HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0
Workunit 26571513
Created 3 Jul 2024, 16:45:37 UTC
Sent 3 Jul 2024, 18:29:59 UTC
Report deadline 7 Jul 2024, 4:05:59 UTC
Received 4 Jul 2024, 20:06:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 199894
Run time 2 hours 12 min 48 sec
CPU time 2 hours 10 min 34 sec
Validate state Valid
Credit 63.71
Device peak FLOPS 4.10 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.96 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.481587
     * GNaL_b in INaL: 0.005489
     * Gto_b in Ito: 0.082264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031458
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.165651
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.050106
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16580521, states[0] = -5.783330, states[40]= 0.003250
Saving checkpoint... 
Iteration: 32563135, states[0] = 5.189782, states[40]= 0.004762
Saving checkpoint... 
Iteration: 49104603, states[0] = -25.538997, states[40]= 0.000673
Saving checkpoint... 
Iteration: 65670283, states[0] = -94.648465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82432478, states[0] = -95.063098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98929402, states[0] = -95.058628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114928922, states[0] = -95.056247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131718838, states[0] = -94.903639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148041659, states[0] = 14.769100, states[40]= 0.005208
Saving checkpoint... 
Iteration: 164602402, states[0] = -21.908988, states[40]= 0.000851
Saving checkpoint... 
Iteration: 180805642, states[0] = -95.001393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196893848, states[0] = -95.043583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213658800, states[0] = -87.926370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230234533, states[0] = -94.926319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247085829, states[0] = -6.863786, states[40]= 0.002999
Saving checkpoint... 
Iteration: 263019271, states[0] = 21.508374, states[40]= 0.010473
Saving checkpoint... 
Iteration: 279467188, states[0] = -95.059551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295942133, states[0] = -95.055144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312406167, states[0] = -95.046754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329103226, states[0] = -22.637550, states[40]= 0.000814
Saving checkpoint... 
Iteration: 344788382, states[0] = -94.987248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361204017, states[0] = -94.874109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377567089, states[0] = 4.365600, states[40]= 0.004680
Saving checkpoint... 
Iteration: 393795934, states[0] = -94.993408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410060120, states[0] = 7.492165, states[40]= 0.004846
Saving checkpoint... 
Iteration: 425706566, states[0] = -94.878945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442406435, states[0] = -95.046735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459047192, states[0] = 12.705830, states[40]= 0.005047
Saving checkpoint... 
Iteration: 475213734, states[0] = -94.892126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491582256, states[0] = -4.215612, states[40]= 0.003548
Saving checkpoint... 
Iteration: 507336059, states[0] = -95.019458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523899607, states[0] = -95.044760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540012537, states[0] = 22.734027, states[40]= 0.029739
Saving checkpoint... 
Iteration: 556563584, states[0] = 5.976842, states[40]= 0.004777
Saving checkpoint... 
Iteration: 572667171, states[0] = -94.110292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588517714, states[0] = 21.810154, states[40]= 0.012445
Saving checkpoint... 
Iteration: 604882647, states[0] = -95.039362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621239006, states[0] = -94.932389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637775501, states[0] = -94.975339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653641717, states[0] = -62.072552, states[40]= 0.000004
Saving checkpoint... 
Iteration: 669780044, states[0] = -94.979630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686408802, states[0] = -95.047223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702930362, states[0] = -95.052433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719442173, states[0] = -95.054870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735173084, states[0] = -94.704081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751502109, states[0] = 43.650566, states[40]= 0.095324
Saving checkpoint... 
Iteration: 768191337, states[0] = -94.848106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784553900, states[0] = 10.070722, states[40]= 0.004938
Saving checkpoint... 
Iteration: 801244420, states[0] = -94.939703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816757616, states[0] = -94.956170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833519044, states[0] = 21.554316, states[40]= 0.010715
Saving checkpoint... 
Iteration: 849963585, states[0] = -95.058597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866273735, states[0] = -94.973466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882878696, states[0] = -95.037818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898564423, states[0] = 5.599114, states[40]= 0.004757
Saving checkpoint... 
Iteration: 915147096, states[0] = -68.924700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931481577, states[0] = -95.061207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948190514, states[0] = -94.846194, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.481587
     * GNaL_b in INaL: 0.005489
     * Gto_b in Ito: 0.082264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031458
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.165651
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.050106
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 948190514
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.846194 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 964776458, states[0] = -94.976060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981694193, states[0] = -94.854035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997514198, states[0] = 22.430310, states[40]= 0.021410
Saving checkpoint... 
Iteration: 1014251649, states[0] = -94.948870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031186718, states[0] = -94.837268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047903351, states[0] = -95.045505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064794044, states[0] = -94.991483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080714886, states[0] = -94.893798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097285164, states[0] = -94.983989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113970303, states[0] = -95.059479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130754168, states[0] = -94.951881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147531288, states[0] = 18.368974, states[40]= 0.005960
Saving checkpoint... 
Iteration: 1163730188, states[0] = -94.919062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180595562, states[0] = -15.382257, states[40]= 0.001413
Saving checkpoint... 
Iteration: 1197258691, states[0] = -94.957179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213914661, states[0] = -95.048419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230325548, states[0] = -95.013129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246902558, states[0] = -95.045158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263683615, states[0] = -94.828300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280181709, states[0] = -94.821203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296759940, states[0] = -94.958549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312983880, states[0] = -95.061280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329155134, states[0] = -81.776519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345716305, states[0] = -94.896131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362006219, states[0] = 26.199385, states[40]= 0.120944
Saving checkpoint... 
Iteration: 1378751905, states[0] = -94.948960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394396909, states[0] = -95.043424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411020965, states[0] = 21.153684, states[40]= 0.009036
Saving checkpoint... 
Iteration: 1427274654, states[0] = -94.974021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443635103, states[0] = -54.535612, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1460391374, states[0] = -95.041688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476267597, states[0] = -94.966823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493114512, states[0] = -33.382441, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1509905080, states[0] = 29.900582, states[40]= 0.115887
Saving checkpoint... 
Iteration: 1526498786, states[0] = -34.941736, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1543218501, states[0] = 21.593982, states[40]= 0.012874
Saving checkpoint... 
Iteration: 1558793576, states[0] = -95.321609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575555754, states[0] = -95.295378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592103412, states[0] = 35.894032, states[40]= 0.118044
Saving checkpoint... 
Iteration: 1608872948, states[0] = -95.315194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625308134, states[0] = -95.238349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641154506, states[0] = -95.097776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657882554, states[0] = -18.904844, states[40]= 0.001148
Saving checkpoint... 
Iteration: 1674453564, states[0] = -95.088291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691234052, states[0] = -85.248861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706941282, states[0] = -95.286114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723870798, states[0] = -6.698964, states[40]= 0.003425
Saving checkpoint... 
Iteration: 1740579870, states[0] = -95.322745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757183075, states[0] = -19.499516, states[40]= 0.001090
Saving checkpoint... 
Iteration: 1774085227, states[0] = -95.195769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789840514, states[0] = 12.387965, states[40]= 0.006058
Saving checkpoint... 
Iteration: 1806372171, states[0] = -95.085529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823198954, states[0] = -94.896487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839859558, states[0] = -95.050730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856473435, states[0] = -95.072258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872448085, states[0] = -95.063231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889112946, states[0] = -32.190607, states[40]= 0.000365
Saving checkpoint... 
Iteration: 1905798002, states[0] = -94.997057, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184303132250_ORdGradInc_k_26-Pueyo_APDR-conf_284_0_r863360634_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.481587
     * GNaL_b in INaL: 0.005489
     * Gto_b in Ito: 0.082264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031458
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.165651
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.050106
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034056
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1905798002
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.997057 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1922136100, states[0] = -55.788544, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1938512332, states[0] = 22.766794, states[40]= 0.031046
Saving checkpoint... 
Iteration: 1955021873, states[0] = 20.943699, states[40]= 0.008468
Saving checkpoint... 
Iteration: 1971430459, states[0] = -95.052053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988153079, states[0] = -78.205694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003799921, states[0] = -94.995608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020326518, states[0] = -95.013258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036914521, states[0] = -95.047884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053375895, states[0] = -95.036073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070159188, states[0] = -88.456073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085809424, states[0] = -95.002276, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.938610
 - CaMKt in component CaMK (millimolar): 0.006906
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.536027
 - nass in component intracellular_ions (millimolar): 6.536087
 - ki in component intracellular_ions (millimolar): 145.442690
 - kss in component intracellular_ions (millimolar): 145.442670
 - cansr in component intracellular_ions (millimolar): 1.307378
 - cajsr in component intracellular_ions (millimolar): 1.269477
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003605
 - hf in component INa (dimensionless): 0.880637
 - hs in component INa (dimensionless): 0.880633
 - j in component INa (dimensionless): 0.880604
 - hsp in component INa (dimensionless): 0.727031
 - jp in component INa (dimensionless): 0.880585
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710950
 - hLp in component INaL (dimensionless): 0.453289
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621679
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696640
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935212
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330179
 - xs1 in component IKs (dimensionless): 0.241314
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:06:23 (128524): called boinc_finish(0)

</stderr_txt>
]]>


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