𝕏

Task 55948469

Name HuVeMOp_20240703184051022857_ORdGradInc_k_26-Pueyo_APDR-conf_581_0
Workunit 26569483
Created 3 Jul 2024, 16:42:55 UTC
Sent 3 Jul 2024, 18:04:02 UTC
Report deadline 7 Jul 2024, 3:40:02 UTC
Received 6 Jul 2024, 15:42:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242033
Run time 2 hours 42 min 16 sec
CPU time 2 hours 42 min 13 sec
Validate state Valid
Credit 61.33
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.92 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Pueyo_APDR-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Pueyo_APDR-conf_581_0_r129612882_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Pueyo_APDR-conf_581_0_r129612882_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.806211
     * GNaL_b in INaL: 0.005564
     * Gto_b in Ito: 0.083832
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032120
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.162418
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.376606
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036660
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13484050, states[0] = -95.126975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27015678, states[0] = 21.532742, states[40]= 0.016636
Saving checkpoint... 
Iteration: 40425141, states[0] = -95.069113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53905409, states[0] = -95.053352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67426143, states[0] = -95.051491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80946441, states[0] = -95.051035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94467332, states[0] = -95.051498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107983688, states[0] = -95.051761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121502192, states[0] = 43.409950, states[40]= 0.096270
Saving checkpoint... 
Iteration: 135023256, states[0] = 20.333679, states[40]= 0.007857
Saving checkpoint... 
Iteration: 148550124, states[0] = 11.203758, states[40]= 0.004996
Saving checkpoint... 
Iteration: 162076081, states[0] = -0.920644, states[40]= 0.004128
Saving checkpoint... 
Iteration: 175596241, states[0] = -17.208063, states[40]= 0.001200
Saving checkpoint... 
Iteration: 188902008, states[0] = -95.031612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202206800, states[0] = -94.865282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215510292, states[0] = 23.058523, states[40]= 0.049602
Saving checkpoint... 
Iteration: 228813061, states[0] = -94.991654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242205515, states[0] = -94.862611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255624337, states[0] = -44.736948, states[40]= 0.000062
Saving checkpoint... 
Iteration: 269044697, states[0] = 13.332185, states[40]= 0.005116
Saving checkpoint... 
Iteration: 282621100, states[0] = -41.382570, states[40]= 0.000103
Saving checkpoint... 
Iteration: 296204514, states[0] = -94.860580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309751410, states[0] = -94.934616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323358468, states[0] = -95.015862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336965313, states[0] = -95.044704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350573915, states[0] = 0.363549, states[40]= 0.004303
Saving checkpoint... 
Iteration: 364179485, states[0] = -94.799517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377664662, states[0] = -93.825768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390961129, states[0] = -95.043995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404260199, states[0] = -94.944996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417560530, states[0] = 6.916997, states[40]= 0.004828
Saving checkpoint... 
Iteration: 430862822, states[0] = -95.017613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444164933, states[0] = -93.900784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457662033, states[0] = -92.717905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471240129, states[0] = -94.919639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484847653, states[0] = -95.010880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498396321, states[0] = -95.029360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511926632, states[0] = -95.037257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525508065, states[0] = 24.122367, states[40]= 0.082926
Saving checkpoint... 
Iteration: 539003459, states[0] = 34.610067, states[40]= 0.143192
Saving checkpoint... 
Iteration: 552304744, states[0] = -94.985561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565625748, states[0] = -46.222234, states[40]= 0.000049
Saving checkpoint... 
Iteration: 579135777, states[0] = -57.211686, states[40]= 0.000008
Saving checkpoint... 
Iteration: 592589644, states[0] = -11.007030, states[40]= 0.002138
Saving checkpoint... 
Iteration: 606008250, states[0] = 23.997719, states[40]= 0.079520
Saving checkpoint... 
Iteration: 619426369, states[0] = -95.037132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632843806, states[0] = -95.008929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646285468, states[0] = -94.970137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659732279, states[0] = -94.908131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673093109, states[0] = -14.195993, states[40]= 0.001583
Saving checkpoint... 
Iteration: 686449409, states[0] = -95.041785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699926173, states[0] = -95.037038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713408309, states[0] = -95.032623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726912251, states[0] = -95.033651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740477430, states[0] = -95.046255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754043074, states[0] = 13.947623, states[40]= 0.005168
Saving checkpoint... 
Iteration: 767608433, states[0] = -28.901185, states[40]= 0.000507
Saving checkpoint... 
Iteration: 781160989, states[0] = -92.025224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794659233, states[0] = -90.434716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808070303, states[0] = 2.307291, states[40]= 0.004518
Saving checkpoint... 
Iteration: 821021633, states[0] = 20.737152, states[40]= 0.008689
Saving checkpoint... 
Iteration: 833864868, states[0] = -95.018198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846663144, states[0] = -93.281281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859503156, states[0] = 36.376338, states[40]= 0.135500
Saving checkpoint... 
Iteration: 872340991, states[0] = -95.007376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885268304, states[0] = -94.953534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898355257, states[0] = -95.014106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911435121, states[0] = -95.038855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924854541, states[0] = -95.013773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938370441, states[0] = -95.020319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951880992, states[0] = -95.024146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965390906, states[0] = -95.027410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978858309, states[0] = -95.015384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992364631, states[0] = -95.018005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005844405, states[0] = -95.008994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019298071, states[0] = -94.980288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032761291, states[0] = -94.945842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046058855, states[0] = 7.641932, states[40]= 0.004859
Saving checkpoint... 
Iteration: 1059381377, states[0] = -95.024213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072432803, states[0] = -95.038268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085433031, states[0] = -95.038308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098534968, states[0] = 16.870507, states[40]= 0.005617
Saving checkpoint... 
Iteration: 1111638004, states[0] = -59.761157, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1125112669, states[0] = -33.006415, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1138678780, states[0] = -94.795198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152238973, states[0] = -94.917597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165793809, states[0] = -94.976834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179357646, states[0] = -95.014976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192765866, states[0] = -94.950764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205882422, states[0] = -95.024481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219268747, states[0] = -94.953791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232408357, states[0] = -95.032318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245603692, states[0] = -24.334787, states[40]= 0.000723
Saving checkpoint... 
Iteration: 1258699941, states[0] = -94.850980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272000929, states[0] = 47.690385, states[40]= 0.021239
Saving checkpoint... 
Iteration: 1285356455, states[0] = -95.014394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298688302, states[0] = -94.826457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312099649, states[0] = -20.447640, states[40]= 0.000931
Saving checkpoint... 
Iteration: 1325634601, states[0] = -55.886266, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1339198927, states[0] = -94.848898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352760549, states[0] = -94.944808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366399115, states[0] = -95.029653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380037538, states[0] = 15.976341, states[40]= 0.005431
Saving checkpoint... 
Iteration: 1393614849, states[0] = -35.136367, states[40]= 0.000248
Saving checkpoint... 
Iteration: 1407128400, states[0] = -49.063361, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1420654451, states[0] = -83.448826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434183130, states[0] = -94.813017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447717242, states[0] = -94.883236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461273727, states[0] = -94.958694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474849374, states[0] = -95.011082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488413032, states[0] = -95.033385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501951260, states[0] = -94.879320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515437374, states[0] = -88.433944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528876412, states[0] = -11.886414, states[40]= 0.002217
Saving checkpoint... 
Iteration: 1542334708, states[0] = 15.106776, states[40]= 0.006545
Saving checkpoint... 
Iteration: 1555827270, states[0] = 18.206775, states[40]= 0.007718
Saving checkpoint... 
Iteration: 1569300490, states[0] = -27.816712, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1582769623, states[0] = -95.302876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596204654, states[0] = -95.223742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609629694, states[0] = -79.552828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623086478, states[0] = -24.398911, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1636594929, states[0] = -33.807345, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1650119886, states[0] = -64.084814, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1663653942, states[0] = -95.092960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677129623, states[0] = -79.642740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690650775, states[0] = -95.052378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704196288, states[0] = -95.211796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717705780, states[0] = -95.229114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730984156, states[0] = -95.319645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744327941, states[0] = -76.614619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757675044, states[0] = -95.312655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771023047, states[0] = -68.645151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1784372717, states[0] = -95.310747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797633794, states[0] = 15.261208, states[40]= 0.006637
Saving checkpoint... 
Iteration: 1810989921, states[0] = -95.096249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824401048, states[0] = -95.064333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837825816, states[0] = -95.022012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851231972, states[0] = -94.923094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864633331, states[0] = -55.292846, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1878053944, states[0] = 9.559653, states[40]= 0.004937
Saving checkpoint... 
Iteration: 1891293924, states[0] = -94.981369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904530140, states[0] = 18.401087, states[40]= 0.006142
Saving checkpoint... 
Iteration: 1917915324, states[0] = -95.035899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931338610, states[0] = -95.006981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944761372, states[0] = -94.946365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958066141, states[0] = 4.348343, states[40]= 0.004686
Saving checkpoint... 
Iteration: 1971366969, states[0] = -95.018760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984671755, states[0] = -94.686159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998017195, states[0] = 21.647004, states[40]= 0.013464
Saving checkpoint... 
Iteration: 2011398486, states[0] = -95.029168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024777882, states[0] = -94.962419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038157320, states[0] = -88.048067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051507136, states[0] = 24.911642, states[40]= 0.101639
Saving checkpoint... 
Iteration: 2064903534, states[0] = -95.030465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078309820, states[0] = -94.988167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091713646, states[0] = -94.876443, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.924109
 - CaMKt in component CaMK (millimolar): 0.006865
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.590110
 - nass in component intracellular_ions (millimolar): 6.590170
 - ki in component intracellular_ions (millimolar): 145.389007
 - kss in component intracellular_ions (millimolar): 145.388988
 - cansr in component intracellular_ions (millimolar): 1.305885
 - cajsr in component intracellular_ions (millimolar): 1.268192
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880386
 - hs in component INa (dimensionless): 0.880382
 - j in component INa (dimensionless): 0.880354
 - hsp in component INa (dimensionless): 0.726558
 - jp in component INa (dimensionless): 0.880335
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710951
 - hLp in component INaL (dimensionless): 0.453997
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623324
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698616
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936601
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001579
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329530
 - xs1 in component IKs (dimensionless): 0.238517
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:42:18 (1510): called boinc_finish(0)

</stderr_txt>
]]>


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