𝕏

Task 55947906

Name HuVeMOp_20240703184051022857_ORdGradInc_k_26-Schmidt_666-conf_378_1
Workunit 26569201
Created 3 Jul 2024, 16:42:29 UTC
Sent 3 Jul 2024, 18:07:21 UTC
Report deadline 6 Jul 2024, 18:07:25 UTC
Received 5 Jul 2024, 1:05:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 57 min 20 sec
CPU time 1 hours 27 min 26 sec
Validate state Valid
Credit 44.44
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.84 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Schmidt_666-conf_378.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Schmidt_666-conf_378_1_r843418855_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Schmidt_666-conf_378_1_r843418855_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.904324
     * GNaL_b in INaL: 0.005914
     * Gto_b in Ito: 0.082507
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031445
     * GKs_b in IKs: 0.001954
     * GK1_b in IK1: 0.162628
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.047554
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030298
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8192231, states[0] = -84.297488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15414744, states[0] = 0.932362, states[40]= 0.000467
Saving checkpoint... 
Iteration: 24125286, states[0] = -44.415346, states[40]= 0.000065
Saving checkpoint... 
Iteration: 32916124, states[0] = -84.481334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 41036602, states[0] = 26.044991, states[40]= 0.000014
Saving checkpoint... 
Iteration: 48309858, states[0] = -84.657635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57653965, states[0] = -84.677837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67267185, states[0] = -84.545255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75824615, states[0] = -79.507255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83825738, states[0] = -80.111005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92469289, states[0] = -52.557495, states[40]= 0.000022
Saving checkpoint... 
Iteration: 101145994, states[0] = -63.653320, states[40]= 0.000005
Saving checkpoint... 
Iteration: 109111699, states[0] = -25.616301, states[40]= 0.000192
Saving checkpoint... 
Iteration: 118403130, states[0] = 11.206280, states[40]= 0.000072
Saving checkpoint... 
Iteration: 127312103, states[0] = -84.657236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135401763, states[0] = 12.450888, states[40]= 0.000059
Saving checkpoint... 
Iteration: 144406344, states[0] = 10.105191, states[40]= 0.000084
Saving checkpoint... 
Iteration: 154540934, states[0] = -84.210865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164511249, states[0] = -83.853423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174048532, states[0] = 23.613775, states[40]= 0.000009
Saving checkpoint... 
Iteration: 185066187, states[0] = 15.031723, states[40]= 0.000038
Saving checkpoint... 
Iteration: 193467843, states[0] = -45.566337, states[40]= 0.000052
Saving checkpoint... 
Iteration: 203169821, states[0] = -82.603249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212100304, states[0] = -7.265332, states[40]= 0.000311
Saving checkpoint... 
Iteration: 220447621, states[0] = -22.355940, states[40]= 0.000190
Saving checkpoint... 
Iteration: 228694933, states[0] = 31.674342, states[40]= 0.005452
Saving checkpoint... 
Iteration: 236813815, states[0] = -57.048551, states[40]= 0.000012
Saving checkpoint... 
Iteration: 245397570, states[0] = 17.643455, states[40]= 0.000024
Saving checkpoint... 
Iteration: 253739348, states[0] = 13.370224, states[40]= 0.000051
Saving checkpoint... 
Iteration: 261888471, states[0] = -84.271819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270890269, states[0] = -84.280749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280035591, states[0] = 30.787723, states[40]= 0.001007
Saving checkpoint... 
Iteration: 289320759, states[0] = -84.655110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298024047, states[0] = 30.781986, states[40]= 0.084526
Saving checkpoint... 
Iteration: 308435603, states[0] = -4.524381, states[40]= 0.000307
Saving checkpoint... 
Iteration: 316959770, states[0] = -84.584463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326291529, states[0] = -84.578310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334079770, states[0] = 11.660528, states[40]= 0.000067
Saving checkpoint... 
Iteration: 343052595, states[0] = 25.612051, states[40]= 0.000012
Saving checkpoint... 
Iteration: 353321675, states[0] = -84.648973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361978406, states[0] = -84.625998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 370023378, states[0] = 30.494444, states[40]= 0.381414
Saving checkpoint... 
Iteration: 378180808, states[0] = -83.148832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387189256, states[0] = -83.854830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395394583, states[0] = 22.838825, states[40]= 0.000009
Saving checkpoint... 
Iteration: 404016051, states[0] = -84.692347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413911554, states[0] = -84.364372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422092732, states[0] = 6.615699, states[40]= 0.000134
Saving checkpoint... 
Iteration: 430815075, states[0] = -47.742842, states[40]= 0.000040
Saving checkpoint... 
Iteration: 439729616, states[0] = 23.083161, states[40]= 0.000009
Saving checkpoint... 
Iteration: 448100211, states[0] = 2.592010, states[40]= 0.000208
Saving checkpoint... 
Iteration: 456202047, states[0] = -84.024051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464580730, states[0] = -84.362879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473202557, states[0] = -84.020304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481479494, states[0] = -42.619532, states[40]= 0.000072
Saving checkpoint... 
Iteration: 488526705, states[0] = -83.817201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497006757, states[0] = -84.667284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505784437, states[0] = -10.178286, states[40]= 0.000288
Saving checkpoint... 
Iteration: 514338610, states[0] = -84.662621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523106965, states[0] = 0.443644, states[40]= 0.000249
Saving checkpoint... 
Iteration: 533598475, states[0] = -84.435362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541238521, states[0] = -84.283775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549899350, states[0] = -84.240614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556864022, states[0] = -83.836729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565693247, states[0] = -84.692373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573575432, states[0] = -84.295522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582486327, states[0] = -44.521495, states[40]= 0.000058
Saving checkpoint... 
Iteration: 591221936, states[0] = -84.141987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600173930, states[0] = -67.430505, states[40]= 0.000003
Saving checkpoint... 
Iteration: 609534681, states[0] = -83.879450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618563753, states[0] = -84.197047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627468764, states[0] = -23.225764, states[40]= 0.000191
Saving checkpoint... 
Iteration: 635355056, states[0] = -84.677886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643837526, states[0] = -60.925199, states[40]= 0.000007
Saving checkpoint... 
Iteration: 652903321, states[0] = -84.229812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661818757, states[0] = -39.325785, states[40]= 0.000099
Saving checkpoint... 
Iteration: 670510701, states[0] = -67.326632, states[40]= 0.000003
Saving checkpoint... 
Iteration: 678550595, states[0] = -84.060694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686632950, states[0] = -84.538896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 694990830, states[0] = -84.608266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703400924, states[0] = 26.923085, states[40]= 0.000025
Saving checkpoint... 
Iteration: 712120457, states[0] = -2.757904, states[40]= 0.000295
Saving checkpoint... 
Iteration: 721040353, states[0] = 31.065755, states[40]= 0.465674
Saving checkpoint... 
Iteration: 729312578, states[0] = -84.571707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737379694, states[0] = 30.894460, states[40]= 0.074694
Saving checkpoint... 
Iteration: 745131938, states[0] = -12.607358, states[40]= 0.000260
Saving checkpoint... 
Iteration: 754882558, states[0] = -84.004657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763439671, states[0] = 8.717647, states[40]= 0.000102
Saving checkpoint... 
Iteration: 772993291, states[0] = -84.602864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781428188, states[0] = 15.650410, states[40]= 0.000035
Saving checkpoint... 
Iteration: 789227617, states[0] = -84.101899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797662186, states[0] = -84.604851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806829310, states[0] = -42.836255, states[40]= 0.000070
Saving checkpoint... 
Iteration: 814260774, states[0] = -84.331237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822241577, states[0] = -84.199517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830286920, states[0] = -84.459808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 838598820, states[0] = -84.350925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847888461, states[0] = -84.016888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855331224, states[0] = -84.602233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864194887, states[0] = -77.155381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872775530, states[0] = 10.436582, states[40]= 0.000080
Saving checkpoint... 
Iteration: 881518699, states[0] = -64.092893, states[40]= 0.000005
Saving checkpoint... 
Iteration: 890369334, states[0] = -84.674538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898044027, states[0] = -84.686004, states[40]= 0.000001
Saving checkpoint... 
Iteration: 906140103, states[0] = -12.732876, states[40]= 0.000258
Saving checkpoint... 
Iteration: 914615512, states[0] = -84.416911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 922674294, states[0] = -84.616035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931291480, states[0] = -84.455366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939619158, states[0] = -84.427752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947492367, states[0] = -31.488757, states[40]= 0.000173
Saving checkpoint... 
Iteration: 955823107, states[0] = -28.240912, states[40]= 0.000190
Saving checkpoint... 
Iteration: 963597016, states[0] = -84.299836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972134006, states[0] = -3.222039, states[40]= 0.000298
Saving checkpoint... 
Iteration: 980792309, states[0] = 3.418816, states[40]= 0.000192
Saving checkpoint... 
Iteration: 989980197, states[0] = -84.527693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997964056, states[0] = -84.464838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006762785, states[0] = 20.765955, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1014530884, states[0] = -71.184239, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1023474361, states[0] = -7.402143, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1032871056, states[0] = -78.247046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041757672, states[0] = 24.043847, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1050147738, states[0] = -13.218980, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1058542411, states[0] = -80.977727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067032048, states[0] = -84.648531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075388931, states[0] = 36.324427, states[40]= 1.024002
Saving checkpoint... 
Iteration: 1083128751, states[0] = 4.745654, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1091702952, states[0] = -84.653399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099369540, states[0] = -84.652395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107720104, states[0] = -84.679692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1115629030, states[0] = -84.428847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123442980, states[0] = 16.870034, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1131741236, states[0] = 31.542588, states[40]= 0.003616
Saving checkpoint... 
Iteration: 1139864045, states[0] = -62.969944, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1148580438, states[0] = -84.106158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157471706, states[0] = 0.683550, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1166388357, states[0] = -84.676438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1175289748, states[0] = -84.383422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183560154, states[0] = -83.737837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191657244, states[0] = -84.524141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199398127, states[0] = 30.531344, states[40]= 0.387996
Saving checkpoint... 
Iteration: 1207578812, states[0] = -84.064631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215381660, states[0] = -84.660766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222795856, states[0] = 8.789874, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1231628233, states[0] = -84.394209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240772837, states[0] = 21.575121, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1248834980, states[0] = -25.206246, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1256847608, states[0] = -38.349525, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1265483458, states[0] = -4.506085, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1274726427, states[0] = -84.672956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282896079, states[0] = -83.570664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290806237, states[0] = 4.464854, states[40]= 0.000171
Saving checkpoint... 
Iteration: 1300215621, states[0] = -75.912746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1308649156, states[0] = -84.469605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1316404866, states[0] = 30.111356, states[40]= 0.284456
Saving checkpoint... 
Iteration: 1324780531, states[0] = 19.854014, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1333086376, states[0] = 31.234302, states[40]= 0.001949
Saving checkpoint... 
Iteration: 1341528400, states[0] = -48.923854, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1349457163, states[0] = 15.348571, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1357140403, states[0] = 6.053136, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1365677092, states[0] = -84.555447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373936725, states[0] = -84.193543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383500217, states[0] = -16.032393, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1391919985, states[0] = -84.047701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400617137, states[0] = -84.278632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408352579, states[0] = -84.573194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417597591, states[0] = -84.130597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426096020, states[0] = 29.867285, states[40]= 0.000333
Saving checkpoint... 
Iteration: 1434942753, states[0] = -84.213752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443237274, states[0] = -83.550807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450748542, states[0] = 30.850210, states[40]= 0.078821
Saving checkpoint... 
Iteration: 1458948048, states[0] = -84.241861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468119536, states[0] = 20.597829, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1477915733, states[0] = -83.947138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487053011, states[0] = -84.638773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494758034, states[0] = 31.703139, states[40]= 0.005848
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.549357
 - CaMKt in component CaMK (millimolar): 0.039231
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.822711
 - nass in component intracellular_ions (millimolar): 6.822866
 - ki in component intracellular_ions (millimolar): 144.836994
 - kss in component intracellular_ions (millimolar): 144.836966
 - cansr in component intracellular_ions (millimolar): 2.058964
 - cajsr in component intracellular_ions (millimolar): 1.812090
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010259
 - hf in component INa (dimensionless): 0.572339
 - hs in component INa (dimensionless): 0.572184
 - j in component INa (dimensionless): 0.571340
 - hsp in component INa (dimensionless): 0.325327
 - jp in component INa (dimensionless): 0.570640
 - mL in component INaL (dimensionless): 0.000354
 - hL in component INaL (dimensionless): 0.345124
 - hLp in component INaL (dimensionless): 0.150010
 - a in component Ito (dimensionless): 0.001253
 - iF in component Ito (dimensionless): 0.999201
 - iS in component Ito (dimensionless): 0.364229
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999201
 - iSp in component Ito (dimensionless): 0.398225
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.841844
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995663
 - jca in component ICaL (dimensionless): 0.998083
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005938
 - xrf in component IKr (dimensionless): 0.000425
 - xrs in component IKr (dimensionless): 0.675633
 - xs1 in component IKs (dimensionless): 0.387275
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996789
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:47:01 (78900): called boinc_finish(0)

</stderr_txt>
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