𝕏

Task 55945974

Name HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843_0
Workunit 26568236
Created 3 Jul 2024, 16:41:22 UTC
Sent 3 Jul 2024, 17:43:17 UTC
Report deadline 6 Jul 2024, 17:43:17 UTC
Received 6 Jul 2024, 16:19:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242052
Run time 1 hours 45 min 48 sec
CPU time 1 hours 17 min 34 sec
Validate state Valid
Credit 47.67
Device peak FLOPS 3.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.79 MB
Peak swap size 5.34 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843_0_r2005660519_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843_0_r2005660519_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.114958
     * GNaL_b in INaL: 0.005526
     * Gto_b in Ito: 0.085357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.165588
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.739840
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033597
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10257887, states[0] = -94.315842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20059654, states[0] = -94.242714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28342215, states[0] = -94.226227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38089012, states[0] = -94.196949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47994240, states[0] = -94.183563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57868133, states[0] = -94.218794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67718770, states[0] = -94.194574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77625868, states[0] = -94.186566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87540984, states[0] = -94.219637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97202826, states[0] = -94.213422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107175403, states[0] = -94.196120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117306228, states[0] = -94.015387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127329333, states[0] = -94.213825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137001906, states[0] = -94.201545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146859934, states[0] = -94.195109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156771817, states[0] = -94.235969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166569668, states[0] = -94.210254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176498820, states[0] = -94.198449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186418857, states[0] = -94.181648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196342075, states[0] = -94.216402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206263337, states[0] = -94.200819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216334094, states[0] = -94.080941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226205264, states[0] = -94.220705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236049145, states[0] = -94.203175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245888295, states[0] = -94.196503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255821837, states[0] = -94.235308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265783806, states[0] = -94.206824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275794667, states[0] = -94.196839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285112371, states[0] = -4.011029, states[40]= 0.000238
Saving checkpoint... 
Iteration: 294751239, states[0] = -94.237258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304740769, states[0] = -94.207306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314780087, states[0] = -94.196658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324883856, states[0] = -94.232484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335171618, states[0] = -94.201206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345329454, states[0] = -94.071419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355361403, states[0] = -94.215252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365286070, states[0] = -94.199837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375531965, states[0] = -94.226348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385703275, states[0] = -94.207357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394917566, states[0] = -94.203854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404928858, states[0] = -94.195212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413943071, states[0] = -94.195075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423678606, states[0] = -94.237112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432975215, states[0] = -94.227919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442796030, states[0] = -94.205314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452508088, states[0] = -94.197311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462548241, states[0] = -94.228471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472291365, states[0] = -94.216333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481717874, states[0] = -94.206333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491963199, states[0] = -94.194362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502074479, states[0] = -94.223453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512104070, states[0] = -94.200553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522153036, states[0] = -46.737325, states[40]= 0.000137
Saving checkpoint... 
Iteration: 532440851, states[0] = -94.211776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542491995, states[0] = -94.196712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552695055, states[0] = -94.236091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563013436, states[0] = -94.201235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573266770, states[0] = -93.887046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583269345, states[0] = -94.216115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593413143, states[0] = -94.196918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603560999, states[0] = -94.229166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613558476, states[0] = -94.208406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623633798, states[0] = -94.195086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633748147, states[0] = -94.234683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643950341, states[0] = -94.201417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653824958, states[0] = -94.193741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663635981, states[0] = -94.234422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673636681, states[0] = -94.206320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683604740, states[0] = -94.194797, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843_0_r2005660519_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703184051022857_ORdGradInc_k_26-Drouin_EPI_6000-conf_843_0_r2005660519_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.114958
     * GNaL_b in INaL: 0.005526
     * Gto_b in Ito: 0.085357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031859
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.165588
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.739840
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033597
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 683604740
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.194797 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 691157448, states[0] = -94.218923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698027951, states[0] = -94.199978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707403068, states[0] = -94.196093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716205639, states[0] = -94.197831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725261656, states[0] = -94.197205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733863591, states[0] = -94.201941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742665836, states[0] = -94.205210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751578397, states[0] = -94.206884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760727803, states[0] = -94.203936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770441637, states[0] = -94.195282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779626933, states[0] = -94.193889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784179283, states[0] = -94.217432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792977026, states[0] = -94.224987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801904303, states[0] = -94.227888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809833465, states[0] = -94.192456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816545698, states[0] = -94.225260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825159538, states[0] = -54.256710, states[40]= 0.000056
Saving checkpoint... 
Iteration: 833801184, states[0] = -94.192434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842133516, states[0] = -94.197594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851006366, states[0] = -94.199033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859800444, states[0] = -94.201923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868106787, states[0] = -94.219335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876465617, states[0] = -94.202919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885769366, states[0] = -94.232139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894609372, states[0] = -94.231341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903362056, states[0] = -94.120256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912455616, states[0] = -94.198173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921924792, states[0] = -94.226097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930815201, states[0] = -94.230313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940312896, states[0] = -94.211975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948948669, states[0] = -94.224903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958228379, states[0] = -94.214420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967678675, states[0] = -94.203178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976927815, states[0] = -94.199076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985919514, states[0] = -94.199121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995469293, states[0] = -94.193274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004854625, states[0] = -94.190792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013759622, states[0] = -94.191226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021330724, states[0] = -94.210817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030504907, states[0] = -94.206281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039699745, states[0] = -94.202217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048718332, states[0] = -94.201811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057939728, states[0] = -94.198267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067419671, states[0] = -94.193091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076360683, states[0] = -94.193510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085811781, states[0] = -94.190369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095212513, states[0] = -93.575349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104550473, states[0] = -94.223714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113926818, states[0] = -94.224489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122905260, states[0] = -94.225298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131736334, states[0] = -94.230984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140415901, states[0] = -94.172762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149713489, states[0] = -94.231206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158675558, states[0] = -94.231263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167451740, states[0] = -94.194278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175833266, states[0] = -94.189540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185082443, states[0] = 13.936429, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1193601181, states[0] = -94.190759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202486517, states[0] = -94.191496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212233782, states[0] = -93.715453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221467264, states[0] = -94.200864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230892365, states[0] = -94.224964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240151878, states[0] = -94.214754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249556017, states[0] = -94.203398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258988293, states[0] = -94.196016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268357879, states[0] = -94.192004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278019335, states[0] = 24.346427, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1287770329, states[0] = -94.228919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297368845, states[0] = -94.207561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307038885, states[0] = -94.194992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321006920, states[0] = -94.219581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330957740, states[0] = -94.195846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340153065, states[0] = -94.193412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349544704, states[0] = -94.189899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358853812, states[0] = -94.187974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368475137, states[0] = -94.202805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377992930, states[0] = -94.219691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387327400, states[0] = -94.207999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396541550, states[0] = -94.202542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406064756, states[0] = -94.193889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415347133, states[0] = -94.190925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424720929, states[0] = -94.188171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434244282, states[0] = -93.773435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443513015, states[0] = -94.213780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452664693, states[0] = -94.228825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461653004, states[0] = -94.228557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470751930, states[0] = -94.227950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479810023, states[0] = -94.226134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488915075, states[0] = -94.221990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498167099, states[0] = -94.212171, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.062145
 - CaMKt in component CaMK (millimolar): 0.001373
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.098776
 - nass in component intracellular_ions (millimolar): 7.098912
 - ki in component intracellular_ions (millimolar): 144.614257
 - kss in component intracellular_ions (millimolar): 144.614245
 - cansr in component intracellular_ions (millimolar): 2.385637
 - cajsr in component intracellular_ions (millimolar): 2.385917
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003939
 - hf in component INa (dimensionless): 0.864648
 - hs in component INa (dimensionless): 0.864649
 - j in component INa (dimensionless): 0.864650
 - hsp in component INa (dimensionless): 0.697563
 - jp in component INa (dimensionless): 0.864650
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706468
 - hLp in component INaL (dimensionless): 0.512600
 - a in component Ito (dimensionless): 0.000660
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999849
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999849
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999562
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005331
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000472
 - xs1 in component IKs (dimensionless): 0.014087
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997549
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:18:49 (18320): called boinc_finish(0)

</stderr_txt>
]]>


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