𝕏

Task 55942949

Name HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pieske_500-conf_376_0
Workunit 26566842
Created 3 Jul 2024, 15:46:15 UTC
Sent 3 Jul 2024, 17:26:41 UTC
Report deadline 6 Jul 2024, 17:26:41 UTC
Received 4 Jul 2024, 11:45:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238472
Run time 2 hours 47 min 14 sec
CPU time 2 hours 35 min 47 sec
Validate state Valid
Credit 41.37
Device peak FLOPS 2.31 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 3.52 MB
Peak swap size 1.29 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pieske_500-conf_376.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pieske_500-conf_376_0_r1115744654_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pieske_500-conf_376_0_r1115744654_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.242735
     * GNaL_b in INaL: 0.005778
     * Gto_b in Ito: 0.081951
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032101
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.163707
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.128246
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034130
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6898535, states[0] = -87.361969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16333474, states[0] = -30.441226, states[40]= 0.000407
Saving checkpoint... 
Iteration: 25077824, states[0] = -22.936617, states[40]= 0.000827
Saving checkpoint... 
Iteration: 34136734, states[0] = -87.151961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43440823, states[0] = -87.381590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52258224, states[0] = 24.430622, states[40]= 0.068239
Saving checkpoint... 
Iteration: 61211796, states[0] = -87.413062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70413095, states[0] = -87.303246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79336780, states[0] = -32.854460, states[40]= 0.000324
Saving checkpoint... 
Iteration: 88626282, states[0] = -84.862891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97573108, states[0] = -15.980371, states[40]= 0.001571
Saving checkpoint... 
Iteration: 106418231, states[0] = -87.312602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115665796, states[0] = -87.305476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124328031, states[0] = -21.992865, states[40]= 0.000901
Saving checkpoint... 
Iteration: 133031022, states[0] = 16.293288, states[40]= 0.006780
Saving checkpoint... 
Iteration: 141870806, states[0] = -79.032044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151494236, states[0] = -87.449412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160571491, states[0] = -13.921780, states[40]= 0.001921
Saving checkpoint... 
Iteration: 169606562, states[0] = -57.544637, states[40]= 0.000009
Saving checkpoint... 
Iteration: 178557009, states[0] = 0.577897, states[40]= 0.005060
Saving checkpoint... 
Iteration: 188040811, states[0] = 11.104370, states[40]= 0.006063
Saving checkpoint... 
Iteration: 197009966, states[0] = 23.804153, states[40]= 0.046337
Saving checkpoint... 
Iteration: 206750755, states[0] = 38.053545, states[40]= 0.012660
Saving checkpoint... 
Iteration: 216069041, states[0] = -11.000348, states[40]= 0.002530
Saving checkpoint... 
Iteration: 225120313, states[0] = -78.275102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234215287, states[0] = -87.409479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243554440, states[0] = 2.491318, states[40]= 0.005311
Saving checkpoint... 
Iteration: 253034959, states[0] = 14.305192, states[40]= 0.006421
Saving checkpoint... 
Iteration: 261947902, states[0] = -87.378681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271164958, states[0] = -87.301557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280421569, states[0] = -87.319203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289720507, states[0] = -87.417506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298067617, states[0] = -9.370098, states[40]= 0.002914
Saving checkpoint... 
Iteration: 307280307, states[0] = 16.648069, states[40]= 0.006864
Saving checkpoint... 
Iteration: 316899896, states[0] = -87.255077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325636061, states[0] = -87.068535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334572478, states[0] = -15.109056, states[40]= 0.001711
Saving checkpoint... 
Iteration: 343995514, states[0] = -87.450238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353377109, states[0] = -85.244367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362308444, states[0] = -0.551115, states[40]= 0.004884
Saving checkpoint... 
Iteration: 371773384, states[0] = 19.707041, states[40]= 0.008316
Saving checkpoint... 
Iteration: 380692013, states[0] = -87.366688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389860099, states[0] = -62.440813, states[40]= 0.000004
Saving checkpoint... 
Iteration: 399129621, states[0] = -86.228500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407822334, states[0] = -14.933278, states[40]= 0.001740
Saving checkpoint... 
Iteration: 416377812, states[0] = -85.584440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425570768, states[0] = -13.039052, states[40]= 0.002092
Saving checkpoint... 
Iteration: 434840624, states[0] = -37.319117, states[40]= 0.000185
Saving checkpoint... 
Iteration: 443559720, states[0] = -1.605222, states[40]= 0.004699
Saving checkpoint... 
Iteration: 452862485, states[0] = -65.942597, states[40]= 0.000002
Saving checkpoint... 
Iteration: 461718778, states[0] = -87.414697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470550918, states[0] = 4.919936, states[40]= 0.005560
Saving checkpoint... 
Iteration: 479896021, states[0] = -87.237750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489299753, states[0] = 5.684943, states[40]= 0.005626
Saving checkpoint... 
Iteration: 498890179, states[0] = -87.184200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507988473, states[0] = -87.441763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517036113, states[0] = 13.695049, states[40]= 0.006338
Saving checkpoint... 
Iteration: 525723682, states[0] = -87.421964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534649706, states[0] = -87.254131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543611779, states[0] = -64.887475, states[40]= 0.000003
Saving checkpoint... 
Iteration: 552616292, states[0] = -71.898180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 561806903, states[0] = 0.663373, states[40]= 0.005073
Saving checkpoint... 
Iteration: 570845175, states[0] = -42.895701, states[40]= 0.000085
Saving checkpoint... 
Iteration: 579258280, states[0] = 24.457135, states[40]= 0.067277
Saving checkpoint... 
Iteration: 588444287, states[0] = -87.371152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597611069, states[0] = -63.842650, states[40]= 0.000003
Saving checkpoint... 
Iteration: 606661250, states[0] = -87.290784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615243401, states[0] = -87.447541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624359576, states[0] = -61.695292, states[40]= 0.000004
Saving checkpoint... 
Iteration: 633035614, states[0] = 13.960328, states[40]= 0.006373
Saving checkpoint... 
Iteration: 642362477, states[0] = -65.930028, states[40]= 0.000002
Saving checkpoint... 
Iteration: 651697737, states[0] = -87.377955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660482280, states[0] = -87.433731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669779217, states[0] = 17.166798, states[40]= 0.007005
Saving checkpoint... 
Iteration: 678724994, states[0] = -87.423703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687865134, states[0] = -70.043800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696795538, states[0] = 8.329310, states[40]= 0.005836
Saving checkpoint... 
Iteration: 705883904, states[0] = -86.930577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714803393, states[0] = 3.234084, states[40]= 0.005394
Saving checkpoint... 
Iteration: 723658223, states[0] = -87.281833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732971086, states[0] = -87.417926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742168080, states[0] = -87.309555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751509738, states[0] = 23.877987, states[40]= 0.048719
Saving checkpoint... 
Iteration: 760865335, states[0] = -70.363285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 767210841, states[0] = -87.401619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776722824, states[0] = -87.420458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786602507, states[0] = -52.174641, states[40]= 0.000021
Saving checkpoint... 
Iteration: 796491736, states[0] = -87.445407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806353245, states[0] = -53.134242, states[40]= 0.000018
Saving checkpoint... 
Iteration: 815736049, states[0] = -87.438436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825597394, states[0] = -45.659373, states[40]= 0.000056
Saving checkpoint... 
Iteration: 835110285, states[0] = -62.706470, states[40]= 0.000004
Saving checkpoint... 
Iteration: 844953495, states[0] = -87.388646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854643147, states[0] = -87.218218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864187490, states[0] = -87.356550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873689034, states[0] = -87.359889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883492361, states[0] = -87.446057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893004324, states[0] = 29.156392, states[40]= 0.133138
Saving checkpoint... 
Iteration: 902730053, states[0] = -87.430516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912237526, states[0] = -87.440188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921768877, states[0] = 21.343847, states[40]= 0.011078
Saving checkpoint... 
Iteration: 931601193, states[0] = -50.478919, states[40]= 0.000027
Saving checkpoint... 
Iteration: 940974422, states[0] = -87.422618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950467664, states[0] = -87.412483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960329006, states[0] = -23.149886, states[40]= 0.000817
Saving checkpoint... 
Iteration: 969943278, states[0] = -87.368708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978431160, states[0] = -87.342105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988202891, states[0] = -87.387393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997470930, states[0] = -87.417426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007112172, states[0] = -65.471405, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1016508347, states[0] = 24.424859, states[40]= 0.066291
Saving checkpoint... 
Iteration: 1025493281, states[0] = -87.446990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035232367, states[0] = -87.433469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044177303, states[0] = -87.332823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053319204, states[0] = -11.187410, states[40]= 0.002487
Saving checkpoint... 
Iteration: 1062701587, states[0] = -87.384898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071888664, states[0] = -87.154459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081761145, states[0] = 23.466285, states[40]= 0.035951
Saving checkpoint... 
Iteration: 1091240803, states[0] = -87.444002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100380921, states[0] = -86.533100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110001607, states[0] = 40.550457, states[40]= 0.071099
Saving checkpoint... 
Iteration: 1119482619, states[0] = -87.433716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129263778, states[0] = 22.802144, states[40]= 0.021588
Saving checkpoint... 
Iteration: 1138753778, states[0] = 30.718344, states[40]= 0.134929
Saving checkpoint... 
Iteration: 1148025699, states[0] = 18.750111, states[40]= 0.007641
Saving checkpoint... 
Iteration: 1157195394, states[0] = -87.372811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166865415, states[0] = -70.489515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176008373, states[0] = 24.412521, states[40]= 0.065911
Saving checkpoint... 
Iteration: 1184891180, states[0] = -87.197641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194086008, states[0] = -31.712307, states[40]= 0.000369
Saving checkpoint... 
Iteration: 1203776459, states[0] = 18.420585, states[40]= 0.007473
Saving checkpoint... 
Iteration: 1213437906, states[0] = -87.357105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223292811, states[0] = 9.953470, states[40]= 0.005964
Saving checkpoint... 
Iteration: 1232694626, states[0] = -87.371189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242114681, states[0] = -69.325422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1251408632, states[0] = -87.282511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260955761, states[0] = -87.392320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270219607, states[0] = -87.415153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280133305, states[0] = -86.874384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290010924, states[0] = 23.525830, states[40]= 0.037669
Saving checkpoint... 
Iteration: 1299849317, states[0] = -48.083793, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1309590313, states[0] = -36.939663, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1319437033, states[0] = -87.355088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329328933, states[0] = -23.059516, states[40]= 0.000823
Saving checkpoint... 
Iteration: 1339203859, states[0] = -87.388813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349071836, states[0] = -14.326283, states[40]= 0.001847
Saving checkpoint... 
Iteration: 1358766978, states[0] = 21.934175, states[40]= 0.013495
Saving checkpoint... 
Iteration: 1368248067, states[0] = -87.452064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378117973, states[0] = -74.610572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387960641, states[0] = -87.400658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397620620, states[0] = -78.721327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407450194, states[0] = -87.381925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416974723, states[0] = -87.422573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426805820, states[0] = 1.483519, states[40]= 0.005186
Saving checkpoint... 
Iteration: 1436652360, states[0] = -87.262707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446288642, states[0] = 12.322392, states[40]= 0.006180
Saving checkpoint... 
Iteration: 1455980357, states[0] = -87.430371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465594871, states[0] = -42.518290, states[40]= 0.000090
Saving checkpoint... 
Iteration: 1475096966, states[0] = -45.122373, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1484744529, states[0] = -87.447971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494578864, states[0] = -22.974338, states[40]= 0.000829
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.329791
 - CaMKt in component CaMK (millimolar): 0.019171
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 6.736576
 - nass in component intracellular_ions (millimolar): 6.736676
 - ki in component intracellular_ions (millimolar): 145.221820
 - kss in component intracellular_ions (millimolar): 145.221793
 - cansr in component intracellular_ions (millimolar): 1.420383
 - cajsr in component intracellular_ions (millimolar): 1.204317
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007760
 - hf in component INa (dimensionless): 0.678803
 - hs in component INa (dimensionless): 0.678702
 - j in component INa (dimensionless): 0.678022
 - hsp in component INa (dimensionless): 0.432432
 - jp in component INa (dimensionless): 0.676137
 - mL in component INaL (dimensionless): 0.000209
 - hL in component INaL (dimensionless): 0.388952
 - hLp in component INaL (dimensionless): 0.182747
 - a in component Ito (dimensionless): 0.001039
 - iF in component Ito (dimensionless): 0.999509
 - iS in component Ito (dimensionless): 0.294521
 - ap in component Ito (dimensionless): 0.000529
 - iFp in component Ito (dimensionless): 0.999509
 - iSp in component Ito (dimensionless): 0.342594
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.858130
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991135
 - jca in component ICaL (dimensionless): 0.991499
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004159
 - xrf in component IKr (dimensionless): 0.001690
 - xrs in component IKr (dimensionless): 0.671476
 - xs1 in component IKs (dimensionless): 0.382122
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996902
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:45:05 (1428): called boinc_finish(0)

</stderr_txt>
]]>


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