𝕏

Task 55940543

Name HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_115_0
Workunit 26565640
Created 3 Jul 2024, 15:44:47 UTC
Sent 3 Jul 2024, 17:14:21 UTC
Report deadline 7 Jul 2024, 2:50:21 UTC
Received 4 Jul 2024, 15:16:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228772
Run time 1 hours 30 min 4 sec
CPU time 1 hours 13 min 46 sec
Validate state Valid
Credit 62.75
Device peak FLOPS 5.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.03 MB
Peak swap size 4.12 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_115.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_115_0_r1727387760_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_115_0_r1727387760_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.082530
     * GNaL_b in INaL: 0.005937
     * Gto_b in Ito: 0.082937
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031446
     * GKs_b in IKs: 0.001897
     * GK1_b in IK1: 0.163811
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.633705
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034432
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10660874, states[0] = -94.037878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25760709, states[0] = -95.006090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38086417, states[0] = -8.488957, states[40]= 0.002673
Saving checkpoint... 
Iteration: 53515286, states[0] = 22.127538, states[40]= 0.017868
Saving checkpoint... 
Iteration: 70441917, states[0] = -95.059266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83436530, states[0] = -95.053809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99405981, states[0] = -95.042958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116230218, states[0] = -94.912052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127691163, states[0] = -94.838583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143057125, states[0] = 8.899881, states[40]= 0.004913
Saving checkpoint... 
Iteration: 158238268, states[0] = -94.921535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172676705, states[0] = -94.759331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189062553, states[0] = 6.626668, states[40]= 0.004820
Saving checkpoint... 
Iteration: 201926669, states[0] = -95.042655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216671475, states[0] = -94.544975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233250595, states[0] = -94.937238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245134951, states[0] = -53.403326, states[40]= 0.000016
Saving checkpoint... 
Iteration: 261420667, states[0] = -95.040971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273747234, states[0] = -94.932790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289330755, states[0] = -95.006738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304989807, states[0] = -95.053247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318452465, states[0] = -95.047559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333564822, states[0] = 5.629519, states[40]= 0.004768
Saving checkpoint... 
Iteration: 348298270, states[0] = -94.984990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365050207, states[0] = 11.690075, states[40]= 0.005013
Saving checkpoint... 
Iteration: 384270756, states[0] = -94.960171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395876231, states[0] = -95.027517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409358037, states[0] = -95.020230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424672933, states[0] = -94.639054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436104636, states[0] = -23.266723, states[40]= 0.000791
Saving checkpoint... 
Iteration: 452633650, states[0] = -51.975277, states[40]= 0.000020
Saving checkpoint... 
Iteration: 468711323, states[0] = -94.876107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481691356, states[0] = -94.836238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498673126, states[0] = -94.648790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511754026, states[0] = -94.941234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527054262, states[0] = 10.091798, states[40]= 0.004953
Saving checkpoint... 
Iteration: 544806746, states[0] = -94.991217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559405498, states[0] = -95.036797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574077091, states[0] = -0.582471, states[40]= 0.004174
Saving checkpoint... 
Iteration: 588420740, states[0] = -95.040739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602959697, states[0] = -95.048636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620308579, states[0] = -94.992474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631154042, states[0] = -78.228463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648217535, states[0] = -94.887164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664018395, states[0] = 21.746240, states[40]= 0.011672
Saving checkpoint... 
Iteration: 677319878, states[0] = -94.999975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694561478, states[0] = 7.101904, states[40]= 0.004842
Saving checkpoint... 
Iteration: 708730659, states[0] = -94.908784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723853371, states[0] = -95.017959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738884900, states[0] = -95.030357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753685644, states[0] = -94.821754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770499421, states[0] = -95.054113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783377622, states[0] = -95.027785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798446581, states[0] = -95.046167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813652761, states[0] = -76.084760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825315063, states[0] = -94.996776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842919164, states[0] = -95.040200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856089889, states[0] = -9.693700, states[40]= 0.002396
Saving checkpoint... 
Iteration: 868076601, states[0] = -0.299289, states[40]= 0.004214
Saving checkpoint... 
Iteration: 882519601, states[0] = 21.508098, states[40]= 0.010300
Saving checkpoint... 
Iteration: 895691306, states[0] = -94.835871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914194307, states[0] = -94.842345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926793426, states[0] = -94.980752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942536788, states[0] = 16.651129, states[40]= 0.005498
Saving checkpoint... 
Iteration: 959409853, states[0] = -95.037741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972947431, states[0] = -95.046222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989913217, states[0] = -95.038609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004328991, states[0] = -95.005270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019379755, states[0] = -95.028405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035809113, states[0] = -94.992595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049535603, states[0] = 17.056374, states[40]= 0.005584
Saving checkpoint... 
Iteration: 1063487591, states[0] = -95.052486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076389108, states[0] = -95.031545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090815799, states[0] = -94.997098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109014200, states[0] = 22.498350, states[40]= 0.021795
Saving checkpoint... 
Iteration: 1122856087, states[0] = -95.018935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139380009, states[0] = -95.028421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155038016, states[0] = 16.223833, states[40]= 0.005419
Saving checkpoint... 
Iteration: 1166306947, states[0] = -94.990980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184335529, states[0] = -95.008811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197751221, states[0] = -94.937322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213893536, states[0] = -95.032870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228356992, states[0] = -95.019271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242267242, states[0] = -94.955946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257544741, states[0] = 13.775689, states[40]= 0.005133
Saving checkpoint... 
Iteration: 1271751117, states[0] = -94.937145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286390410, states[0] = -95.031837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303258335, states[0] = -94.945918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315666226, states[0] = -93.517008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331460183, states[0] = -95.048272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346204481, states[0] = -94.862608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360093260, states[0] = -12.658633, states[40]= 0.001829
Saving checkpoint... 
Iteration: 1376470898, states[0] = -95.049953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389784871, states[0] = -94.973136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405284274, states[0] = -94.972590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419632538, states[0] = -50.768311, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1431133358, states[0] = -51.656974, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1449277215, states[0] = -94.965975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463931408, states[0] = -95.042660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482200879, states[0] = -94.855437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499920917, states[0] = -95.040225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515226495, states[0] = -95.219092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531043021, states[0] = -93.076856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546447226, states[0] = -95.270674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558966361, states[0] = -95.132284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575026523, states[0] = 18.776342, states[40]= 0.007940
Saving checkpoint... 
Iteration: 1588039473, states[0] = -91.479337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603656095, states[0] = -95.096419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619455367, states[0] = 4.654959, states[40]= 0.005356
Saving checkpoint... 
Iteration: 1632965996, states[0] = -2.336442, states[40]= 0.004395
Saving checkpoint... 
Iteration: 1651363895, states[0] = -95.136057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664470418, states[0] = -5.988141, states[40]= 0.003598
Saving checkpoint... 
Iteration: 1680244389, states[0] = -95.284149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697715729, states[0] = 22.314032, states[40]= 0.018377
Saving checkpoint... 
Iteration: 1710815407, states[0] = -95.245379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727948457, states[0] = -95.288809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741952681, states[0] = -95.055765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756111570, states[0] = -95.239253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772239894, states[0] = -92.111775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782942355, states[0] = 11.586664, states[40]= 0.005985
Saving checkpoint... 
Iteration: 1798449029, states[0] = -95.289416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812966525, states[0] = -95.094683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826448413, states[0] = -95.077637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844225084, states[0] = -94.918523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856066368, states[0] = 4.610085, states[40]= 0.004719
Saving checkpoint... 
Iteration: 1870001019, states[0] = 48.871934, states[40]= 0.027613
Saving checkpoint... 
Iteration: 1884563256, states[0] = 6.200972, states[40]= 0.004804
Saving checkpoint... 
Iteration: 1897816517, states[0] = -95.000940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913088505, states[0] = -8.653399, states[40]= 0.002617
Saving checkpoint... 
Iteration: 1925858846, states[0] = -95.021313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941827250, states[0] = -95.004706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956559839, states[0] = 7.786947, states[40]= 0.004871
Saving checkpoint... 
Iteration: 1970658760, states[0] = -86.388707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987941553, states[0] = -95.044685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999597562, states[0] = -16.638009, states[40]= 0.001264
Saving checkpoint... 
Iteration: 2013965387, states[0] = -95.048783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027056278, states[0] = 9.276272, states[40]= 0.004925
Saving checkpoint... 
Iteration: 2040462244, states[0] = -95.048187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057256820, states[0] = -94.943647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068986106, states[0] = -95.051651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083919902, states[0] = -95.039585, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.929201
 - CaMKt in component CaMK (millimolar): 0.006929
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.559385
 - nass in component intracellular_ions (millimolar): 6.559445
 - ki in component intracellular_ions (millimolar): 145.419197
 - kss in component intracellular_ions (millimolar): 145.419177
 - cansr in component intracellular_ions (millimolar): 1.308566
 - cajsr in component intracellular_ions (millimolar): 1.270569
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880475
 - hs in component INa (dimensionless): 0.880470
 - j in component INa (dimensionless): 0.880441
 - hsp in component INa (dimensionless): 0.726724
 - jp in component INa (dimensionless): 0.880422
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710476
 - hLp in component INaL (dimensionless): 0.452328
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620662
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695370
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934529
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001592
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334762
 - xs1 in component IKs (dimensionless): 0.242817
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:15:20 (50831): called boinc_finish(0)

</stderr_txt>
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