𝕏

Task 55940249

Name HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_203_1
Workunit 26565493
Created 3 Jul 2024, 15:44:36 UTC
Sent 3 Jul 2024, 17:14:21 UTC
Report deadline 7 Jul 2024, 2:50:21 UTC
Received 4 Jul 2024, 17:44:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228772
Run time 1 hours 28 min 43 sec
CPU time 1 hours 13 min 34 sec
Validate state Valid
Credit 63.84
Device peak FLOPS 5.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.98 MB
Peak swap size 4.12 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_203.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r174534471_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174428986478_ORdGradInc_k_26-Pueyo_APDR-conf_203_1_r174534471_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.389440
     * GNaL_b in INaL: 0.005830
     * Gto_b in Ito: 0.083225
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032266
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.167895
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.280199
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032052
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8790766, states[0] = -95.057712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25217076, states[0] = -94.923659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40553348, states[0] = 9.525019, states[40]= 0.004957
Saving checkpoint... 
Iteration: 55335620, states[0] = -95.009788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72147168, states[0] = -72.441093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 84539842, states[0] = 15.170986, states[40]= 0.005297
Saving checkpoint... 
Iteration: 98099414, states[0] = -20.211601, states[40]= 0.000953
Saving checkpoint... 
Iteration: 113651814, states[0] = -79.136092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131451000, states[0] = -95.029728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151299553, states[0] = -94.969220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166482935, states[0] = -95.033364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180601592, states[0] = -22.010938, states[40]= 0.000846
Saving checkpoint... 
Iteration: 197542491, states[0] = 14.304372, states[40]= 0.005187
Saving checkpoint... 
Iteration: 211223407, states[0] = -94.882056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227681268, states[0] = -94.797435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243219849, states[0] = -94.876064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257413909, states[0] = -95.019887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275880482, states[0] = -95.010014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290158850, states[0] = -90.119958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305430064, states[0] = -95.023585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320716267, states[0] = -94.869856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331455269, states[0] = -95.028414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348008761, states[0] = 23.800743, states[40]= 0.070584
Saving checkpoint... 
Iteration: 361493105, states[0] = -95.033830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375774333, states[0] = -94.946437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391033072, states[0] = 17.644522, states[40]= 0.005771
Saving checkpoint... 
Iteration: 402091313, states[0] = -12.253592, states[40]= 0.001909
Saving checkpoint... 
Iteration: 419941522, states[0] = -95.025848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433933467, states[0] = -95.024216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449330108, states[0] = -94.987723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464797598, states[0] = -94.966452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476968532, states[0] = -95.030447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490501239, states[0] = 49.093708, states[40]= 0.043229
Saving checkpoint... 
Iteration: 502223510, states[0] = -94.881849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520317345, states[0] = -94.980135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535384586, states[0] = -95.011204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551623531, states[0] = -43.413436, states[40]= 0.000077
Saving checkpoint... 
Iteration: 568652465, states[0] = -79.840967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581121442, states[0] = -41.265342, states[40]= 0.000107
Saving checkpoint... 
Iteration: 599435640, states[0] = -95.024561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615319792, states[0] = -94.981595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629487014, states[0] = -95.032909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645828959, states[0] = -94.986958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657639890, states[0] = -61.555967, states[40]= 0.000004
Saving checkpoint... 
Iteration: 673988738, states[0] = -95.033098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688285820, states[0] = -94.956740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700933378, states[0] = -95.024029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719448063, states[0] = -95.026891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731687033, states[0] = -94.812560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746128840, states[0] = -49.054347, states[40]= 0.000032
Saving checkpoint... 
Iteration: 764926955, states[0] = -95.022602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777725423, states[0] = -94.884740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794133468, states[0] = -54.151297, states[40]= 0.000014
Saving checkpoint... 
Iteration: 807872722, states[0] = -95.006891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821089896, states[0] = -10.973676, states[40]= 0.002149
Saving checkpoint... 
Iteration: 836536819, states[0] = 16.370172, states[40]= 0.005466
Saving checkpoint... 
Iteration: 847094423, states[0] = -15.146688, states[40]= 0.001451
Saving checkpoint... 
Iteration: 862574206, states[0] = 0.359293, states[40]= 0.004314
Saving checkpoint... 
Iteration: 878215754, states[0] = -94.868606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894964707, states[0] = -95.029596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911362932, states[0] = -95.003042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922998790, states[0] = -95.034135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940188817, states[0] = -94.816413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954561261, states[0] = 6.739633, states[40]= 0.004831
Saving checkpoint... 
Iteration: 966625231, states[0] = -45.191930, states[40]= 0.000059
Saving checkpoint... 
Iteration: 983995818, states[0] = -95.033755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997232130, states[0] = -94.894917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012904659, states[0] = -95.016940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028484007, states[0] = -95.032271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043831048, states[0] = -94.987867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062293084, states[0] = -94.962540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074987111, states[0] = -95.032641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092908063, states[0] = -95.017806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109732642, states[0] = -94.895605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121553225, states[0] = 10.127816, states[40]= 0.004956
Saving checkpoint... 
Iteration: 1139478444, states[0] = -95.031457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156182550, states[0] = -94.800819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169282898, states[0] = -94.953879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185406677, states[0] = -95.017378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197835164, states[0] = -94.989989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214750971, states[0] = -94.920332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232522703, states[0] = 20.620989, states[40]= 0.008045
Saving checkpoint... 
Iteration: 1244181426, states[0] = -94.797199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260305168, states[0] = -94.971529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276975748, states[0] = -95.030995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293352610, states[0] = -94.998411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309475336, states[0] = -95.030917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321129075, states[0] = -49.309056, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1338821268, states[0] = -94.982038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353284941, states[0] = -94.955558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368422966, states[0] = -95.021319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384333359, states[0] = -94.988909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397217520, states[0] = -94.871318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413693243, states[0] = -94.825478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425354600, states[0] = -94.999208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441200103, states[0] = -94.839257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458994507, states[0] = -95.033303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468811280, states[0] = -94.975605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486178945, states[0] = -94.786959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497754181, states[0] = -94.924040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515739868, states[0] = -91.607241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531899793, states[0] = -37.310673, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1542794825, states[0] = -95.167037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559636105, states[0] = -95.238450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574382795, states[0] = -95.286951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589719224, states[0] = 21.096584, states[40]= 0.011954
Saving checkpoint... 
Iteration: 1605212633, states[0] = -95.214039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618932206, states[0] = -84.099368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636588847, states[0] = -26.658542, states[40]= 0.000618
Saving checkpoint... 
Iteration: 1651373588, states[0] = -95.139221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664609597, states[0] = -95.211200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681034082, states[0] = -87.551539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694406583, states[0] = 26.768054, states[40]= 0.105670
Saving checkpoint... 
Iteration: 1711761341, states[0] = -95.275681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725189737, states[0] = -95.175228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743133635, states[0] = -86.826339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756924398, states[0] = -70.273239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1771858567, states[0] = 2.159977, states[40]= 0.005103
Saving checkpoint... 
Iteration: 1788446183, states[0] = -94.869963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801707886, states[0] = -94.910252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817152740, states[0] = -85.769287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833177671, states[0] = -94.810149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844987661, states[0] = -95.049890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861508576, states[0] = 23.834047, states[40]= 0.073768
Saving checkpoint... 
Iteration: 1876046626, states[0] = 12.617154, states[40]= 0.005071
Saving checkpoint... 
Iteration: 1889806337, states[0] = -94.976614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908760055, states[0] = -94.933230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920168645, states[0] = -94.540295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934853989, states[0] = -94.999802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952605641, states[0] = -25.895612, states[40]= 0.000658
Saving checkpoint... 
Iteration: 1964419885, states[0] = -95.020684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979005017, states[0] = 28.574510, states[40]= 0.146530
Saving checkpoint... 
Iteration: 1993204371, states[0] = -94.847333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005301687, states[0] = -94.968646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022022329, states[0] = 20.708586, states[40]= 0.008228
Saving checkpoint... 
Iteration: 2034429195, states[0] = -95.022306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050908116, states[0] = -95.017201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066822179, states[0] = -94.982097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081976944, states[0] = -95.030617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098645070, states[0] = -68.169197, states[40]= 0.000001
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909360
 - CaMKt in component CaMK (millimolar): 0.006938
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.596988
 - nass in component intracellular_ions (millimolar): 6.597048
 - ki in component intracellular_ions (millimolar): 145.380801
 - kss in component intracellular_ions (millimolar): 145.380782
 - cansr in component intracellular_ions (millimolar): 1.311291
 - cajsr in component intracellular_ions (millimolar): 1.273494
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880131
 - hs in component INa (dimensionless): 0.880127
 - j in component INa (dimensionless): 0.880099
 - hsp in component INa (dimensionless): 0.726077
 - jp in component INa (dimensionless): 0.880080
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710575
 - hLp in component INaL (dimensionless): 0.453620
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622937
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698150
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936070
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001601
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329868
 - xs1 in component IKs (dimensionless): 0.239351
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:43:54 (57942): called boinc_finish(0)

</stderr_txt>
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