𝕏

Task 55939444

Name HuVeMOp_20240703174051667545_ORdGradInc_k_26-Coppini_2000-conf_581_0
Workunit 26565091
Created 3 Jul 2024, 15:44:00 UTC
Sent 3 Jul 2024, 17:03:13 UTC
Report deadline 6 Jul 2024, 17:03:13 UTC
Received 4 Jul 2024, 0:19:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 46 sec
CPU time 1 hours 2 min 21 sec
Validate state Valid
Credit 43.67
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.96 MB
Peak swap size 4.10 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Coppini_2000-conf_581.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Coppini_2000-conf_581_0_r384836153_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Coppini_2000-conf_581_0_r384836153_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.806211
     * GNaL_b in INaL: 0.005564
     * Gto_b in Ito: 0.083832
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032120
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.162418
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.376606
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036660
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12689634, states[0] = -94.795929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25328257, states[0] = -94.608074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37429722, states[0] = -94.667174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50009179, states[0] = 26.636198, states[40]= 0.063521
Saving checkpoint... 
Iteration: 61525951, states[0] = -94.678505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74264131, states[0] = -94.424903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86947170, states[0] = -94.684301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98249585, states[0] = -94.376897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110711310, states[0] = -94.682129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123630619, states[0] = -94.677218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135978130, states[0] = -94.676780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149729658, states[0] = -94.679266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162502645, states[0] = -94.655546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174443414, states[0] = -94.634132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187864991, states[0] = -94.677385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201320708, states[0] = -94.526370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214375761, states[0] = -94.589828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226928878, states[0] = -94.675573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240642721, states[0] = -94.674548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252958487, states[0] = -94.674698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265672292, states[0] = -94.675930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279213948, states[0] = -94.242231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291942269, states[0] = -94.674953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304253146, states[0] = -94.380417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317219397, states[0] = -94.264458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329545774, states[0] = -94.663462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342611411, states[0] = -94.671882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355099309, states[0] = -3.184011, states[40]= 0.003963
Saving checkpoint... 
Iteration: 368057802, states[0] = 16.855892, states[40]= 0.003287
Saving checkpoint... 
Iteration: 380129299, states[0] = -28.714884, states[40]= 0.001192
Saving checkpoint... 
Iteration: 392899922, states[0] = -94.675702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405217008, states[0] = -94.254769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416092239, states[0] = 1.374078, states[40]= 0.004502
Saving checkpoint... 
Iteration: 427739641, states[0] = -94.677160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441239691, states[0] = -94.337713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453399622, states[0] = -94.607731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465882417, states[0] = -94.675929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476839396, states[0] = -94.676652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489007739, states[0] = 27.005467, states[40]= 0.102058
Saving checkpoint... 
Iteration: 501068305, states[0] = 12.912032, states[40]= 0.003953
Saving checkpoint... 
Iteration: 514283284, states[0] = -94.457189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527770293, states[0] = -94.677115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539795176, states[0] = -94.677010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550909759, states[0] = -94.675204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563270183, states[0] = -94.426394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575990440, states[0] = -94.673194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587904346, states[0] = -94.675257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599954586, states[0] = -94.674062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612400776, states[0] = -94.608245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624754330, states[0] = -94.676909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638338556, states[0] = -94.549635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649923415, states[0] = -94.674719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660989539, states[0] = -94.673066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671384379, states[0] = -94.595924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682960429, states[0] = -94.673769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695283754, states[0] = -94.457891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707769565, states[0] = -94.676794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719389610, states[0] = -94.599943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731387329, states[0] = -94.598157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744600581, states[0] = -94.670131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758420745, states[0] = -94.620526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769695330, states[0] = -94.675743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780836683, states[0] = -94.676149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792338563, states[0] = -94.549368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804589498, states[0] = -94.668842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817326328, states[0] = -94.533008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830579228, states[0] = -94.667569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842875447, states[0] = -94.675392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855542591, states[0] = -94.661940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867422491, states[0] = -94.621320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879790996, states[0] = -94.676429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890975793, states[0] = -94.673010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904658559, states[0] = -94.674088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916725082, states[0] = -94.676113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929507682, states[0] = -94.654265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940302053, states[0] = -94.493846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950949627, states[0] = -94.673559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963268396, states[0] = -94.421160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975967405, states[0] = -94.673072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988845112, states[0] = -94.675655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000660223, states[0] = -94.673999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012827895, states[0] = -94.675853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025516709, states[0] = -94.656291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037212158, states[0] = -94.232684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049606468, states[0] = -94.670160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062909223, states[0] = -94.674304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075600421, states[0] = -94.669526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089175910, states[0] = -74.911186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099158846, states[0] = -55.768438, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1111395820, states[0] = -94.603860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124566244, states[0] = -94.665297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136320077, states[0] = -94.523300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149600754, states[0] = -94.669427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160293875, states[0] = -94.478022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172280630, states[0] = -94.450111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185138332, states[0] = -36.601413, states[40]= 0.000589
Saving checkpoint... 
Iteration: 1197535958, states[0] = -94.660086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210069672, states[0] = 12.358795, states[40]= 0.004029
Saving checkpoint... 
Iteration: 1222886024, states[0] = -94.674509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234941387, states[0] = -94.673254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246922894, states[0] = -94.673669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259702922, states[0] = -94.675071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271358904, states[0] = -94.571638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283708095, states[0] = -94.675149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296293426, states[0] = -94.476892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309039311, states[0] = 22.720798, states[40]= 0.002157
Saving checkpoint... 
Iteration: 1322339241, states[0] = -94.549267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334215764, states[0] = -94.247978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345890077, states[0] = -94.674208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357853487, states[0] = -94.674866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370219354, states[0] = -94.262357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382517634, states[0] = -94.655871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394449484, states[0] = -94.633791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406278052, states[0] = -94.443809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418818472, states[0] = -94.675242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431543101, states[0] = -94.661007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442841022, states[0] = -94.674909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454959538, states[0] = -94.672417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466760989, states[0] = -94.675434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478255929, states[0] = -94.386399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488830301, states[0] = -94.674975, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.547237
 - CaMKt in component CaMK (millimolar): 0.004166
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.495757
 - nass in component intracellular_ions (millimolar): 6.495842
 - ki in component intracellular_ions (millimolar): 145.418152
 - kss in component intracellular_ions (millimolar): 145.418137
 - cansr in component intracellular_ions (millimolar): 1.584097
 - cajsr in component intracellular_ions (millimolar): 1.583405
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003750
 - hf in component INa (dimensionless): 0.873709
 - hs in component INa (dimensionless): 0.873710
 - j in component INa (dimensionless): 0.873716
 - hsp in component INa (dimensionless): 0.714116
 - jp in component INa (dimensionless): 0.873719
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.719574
 - hLp in component INaL (dimensionless): 0.511810
 - a in component Ito (dimensionless): 0.000639
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.892485
 - ap in component Ito (dimensionless): 0.000325
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.932219
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975849
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002675
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097147
 - xs1 in component IKs (dimensionless): 0.124032
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997429
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:15:59 (99246): called boinc_finish(0)

</stderr_txt>
]]>