𝕏

Task 55938689

Name HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878_0
Workunit 26564714
Created 3 Jul 2024, 15:43:24 UTC
Sent 3 Jul 2024, 17:03:13 UTC
Report deadline 6 Jul 2024, 17:03:13 UTC
Received 3 Jul 2024, 23:12:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241141
Run time 1 hours 15 min 15 sec
CPU time 1 hours 2 min 17 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 5.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.82 MB
Peak swap size 4.10 GB
Peak disk usage 0.71 MB

Stderr output

<core_client_version>7.24.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878_0_r188281694_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878_0_r188281694_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 106.074724
     * GNaL_b in INaL: 0.005686
     * Gto_b in Ito: 0.083768
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032042
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.164112
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.821394
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035984
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13701077, states[0] = -65.686192, states[40]= 0.000005
Saving checkpoint... 
Iteration: 26101562, states[0] = 8.178051, states[40]= 0.000015
Saving checkpoint... 
Iteration: 37940956, states[0] = -86.912954, states[40]= 0.000002
Saving checkpoint... 
Iteration: 51514543, states[0] = 30.570013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64730702, states[0] = -86.395024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76497791, states[0] = -86.986748, states[40]= 0.000002
Saving checkpoint... 
Iteration: 88998498, states[0] = -86.994349, states[40]= 0.000002
Saving checkpoint... 
Iteration: 101702591, states[0] = -85.844137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112598932, states[0] = 6.381997, states[40]= 0.000034
Saving checkpoint... 
Iteration: 125782603, states[0] = -86.704234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137849341, states[0] = -86.881522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 149752690, states[0] = -86.566989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162633149, states[0] = -17.840681, states[40]= 0.000178
Saving checkpoint... 
Iteration: 174252945, states[0] = -86.568733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186826346, states[0] = -86.836643, states[40]= 0.000002
Saving checkpoint... 
Iteration: 198707177, states[0] = -86.190057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211226052, states[0] = -86.391852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223279666, states[0] = -86.693464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236333867, states[0] = -86.850953, states[40]= 0.000002
Saving checkpoint... 
Iteration: 247525482, states[0] = 31.694550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259553148, states[0] = 25.818980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273015850, states[0] = 30.662095, states[40]= -0.000000
Saving checkpoint... 
Iteration: 285504356, states[0] = 18.934792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 297499523, states[0] = -87.001477, states[40]= 0.000002
Saving checkpoint... 
Iteration: 309650901, states[0] = -32.552894, states[40]= 0.000423
Saving checkpoint... 
Iteration: 321662988, states[0] = -43.774581, states[40]= 0.000181
Saving checkpoint... 
Iteration: 333451039, states[0] = -86.979121, states[40]= 0.000002
Saving checkpoint... 
Iteration: 345730513, states[0] = -86.417725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357374825, states[0] = -86.911839, states[40]= 0.000002
Saving checkpoint... 
Iteration: 368657172, states[0] = -38.175909, states[40]= 0.000302
Saving checkpoint... 
Iteration: 381072193, states[0] = 18.579694, states[40]= 0.000002
Saving checkpoint... 
Iteration: 393073943, states[0] = 17.838869, states[40]= 0.000002
Saving checkpoint... 
Iteration: 405906479, states[0] = -86.943448, states[40]= 0.000002
Saving checkpoint... 
Iteration: 417982311, states[0] = -86.988892, states[40]= 0.000002
Saving checkpoint... 
Iteration: 430962142, states[0] = -86.979475, states[40]= 0.000002
Saving checkpoint... 
Iteration: 442119698, states[0] = -6.638823, states[40]= 0.000150
Saving checkpoint... 
Iteration: 455384175, states[0] = -86.917850, states[40]= 0.000002
Saving checkpoint... 
Iteration: 466958141, states[0] = -86.975496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 479638728, states[0] = -22.564395, states[40]= 0.000285
Saving checkpoint... 
Iteration: 490399798, states[0] = -86.932518, states[40]= 0.000002
Saving checkpoint... 
Iteration: 503108065, states[0] = 1.141867, states[40]= 0.000081
Saving checkpoint... 
Iteration: 516114117, states[0] = -2.623176, states[40]= 0.000121
Saving checkpoint... 
Iteration: 527548428, states[0] = 27.324621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540639136, states[0] = -22.886943, states[40]= 0.000295
Saving checkpoint... 
Iteration: 552875496, states[0] = -86.901875, states[40]= 0.000002
Saving checkpoint... 
Iteration: 566545989, states[0] = 28.041252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578714295, states[0] = -86.272602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591038926, states[0] = 29.840029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603008514, states[0] = 26.403155, states[40]= -0.000000
Saving checkpoint... 
Iteration: 615589432, states[0] = 10.833382, states[40]= 0.000014
Saving checkpoint... 
Iteration: 628323004, states[0] = -86.805282, states[40]= 0.000002
Saving checkpoint... 
Iteration: 641370766, states[0] = -86.890747, states[40]= 0.000002
Saving checkpoint... 
Iteration: 654640417, states[0] = -23.901620, states[40]= 0.000328
Saving checkpoint... 
Iteration: 666211467, states[0] = -86.236660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678095023, states[0] = 8.111171, states[40]= 0.000025
Saving checkpoint... 
Iteration: 690319798, states[0] = -86.794132, states[40]= 0.000002
Saving checkpoint... 
Iteration: 702818307, states[0] = -86.789751, states[40]= 0.000002
Saving checkpoint... 
Iteration: 715334138, states[0] = -86.825022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 725886808, states[0] = -86.905859, states[40]= 0.000002
Saving checkpoint... 
Iteration: 736778519, states[0] = -86.660265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 749110165, states[0] = -0.096564, states[40]= 0.000094
Saving checkpoint... 
Iteration: 760547747, states[0] = 27.534060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772814387, states[0] = -86.775838, states[40]= 0.000002
Saving checkpoint... 
Iteration: 785173663, states[0] = -54.961098, states[40]= 0.000049
Saving checkpoint... 
Iteration: 798648297, states[0] = -30.288833, states[40]= 0.000442
Saving checkpoint... 
Iteration: 812463762, states[0] = -86.959183, states[40]= 0.000002
Saving checkpoint... 
Iteration: 823978769, states[0] = -86.965093, states[40]= 0.000002
Saving checkpoint... 
Iteration: 835848917, states[0] = -86.846358, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847833485, states[0] = -86.816307, states[40]= 0.000002
Saving checkpoint... 
Iteration: 859951614, states[0] = -86.950389, states[40]= 0.000002
Saving checkpoint... 
Iteration: 872448181, states[0] = -86.947786, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884006758, states[0] = 24.324410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897521488, states[0] = 31.646419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909452751, states[0] = -86.948260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 921873608, states[0] = -86.878956, states[40]= 0.000002
Saving checkpoint... 
Iteration: 934507915, states[0] = 25.785876, states[40]= -0.000000
Saving checkpoint... 
Iteration: 945868048, states[0] = -86.870100, states[40]= 0.000002
Saving checkpoint... 
Iteration: 958048369, states[0] = 27.352365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971138801, states[0] = -22.581909, states[40]= 0.000283
Saving checkpoint... 
Iteration: 983412943, states[0] = -86.917164, states[40]= 0.000002
Saving checkpoint... 
Iteration: 995281073, states[0] = -86.655918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006776522, states[0] = -86.636869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019063541, states[0] = 22.085236, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031810512, states[0] = -86.750982, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1043583028, states[0] = 13.835670, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1055878371, states[0] = -86.877599, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1068682032, states[0] = -65.268385, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1081990147, states[0] = -86.955159, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1094739181, states[0] = -86.434730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107494537, states[0] = -86.955247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1121073608, states[0] = 17.999068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1135116711, states[0] = -4.373948, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1147891299, states[0] = -86.887437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1159474583, states[0] = -86.944884, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1171012501, states[0] = 29.317127, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1183644157, states[0] = -26.850168, states[40]= 0.000409
Saving checkpoint... 
Iteration: 1195330545, states[0] = -86.790724, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1208345335, states[0] = -86.819311, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1221128304, states[0] = -13.732406, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1234454163, states[0] = -86.931090, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1247075649, states[0] = 17.126670, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1259533613, states[0] = 30.883344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271555889, states[0] = 24.906088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284791249, states[0] = -86.677301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298374555, states[0] = -86.859346, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1311267014, states[0] = -86.577735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1323524291, states[0] = 31.740166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335765015, states[0] = -86.566872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348181830, states[0] = -64.929611, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1360140821, states[0] = -24.164463, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1372070766, states[0] = 19.198783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383965775, states[0] = -86.928639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1396722339, states[0] = -86.295387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409798957, states[0] = -86.695826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1421706558, states[0] = -86.100256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432375786, states[0] = -86.853505, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1444774801, states[0] = -86.604981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456675321, states[0] = -56.747953, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1468799447, states[0] = -86.694053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481045908, states[0] = 28.084968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493978448, states[0] = -86.928075, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.811292
 - CaMKt in component CaMK (millimolar): 0.025066
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.056535
 - nass in component intracellular_ions (millimolar): 8.056688
 - ki in component intracellular_ions (millimolar): 143.339919
 - kss in component intracellular_ions (millimolar): 143.339880
 - cansr in component intracellular_ions (millimolar): 2.046445
 - cajsr in component intracellular_ions (millimolar): 1.981290
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008175
 - hf in component INa (dimensionless): 0.659948
 - hs in component INa (dimensionless): 0.659918
 - j in component INa (dimensionless): 0.659745
 - hsp in component INa (dimensionless): 0.411903
 - jp in component INa (dimensionless): 0.659621
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.456358
 - hLp in component INaL (dimensionless): 0.222618
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999463
 - iS in component Ito (dimensionless): 0.534861
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999463
 - iSp in component Ito (dimensionless): 0.578572
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877486
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999619
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003817
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507947
 - xs1 in component IKs (dimensionless): 0.333171
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997029
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
15:06:06 (98136): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878_0_r188281694_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-BASE_MID-conf_878_0_r188281694_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 106.074724
     * GNaL_b in INaL: 0.005686
     * Gto_b in Ito: 0.083768
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032042
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.164112
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.821394
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035984
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1493978448
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.928075 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.811292
 - CaMKt in component CaMK (millimolar): 0.025066
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.056535
 - nass in component intracellular_ions (millimolar): 8.056688
 - ki in component intracellular_ions (millimolar): 143.339919
 - kss in component intracellular_ions (millimolar): 143.339880
 - cansr in component intracellular_ions (millimolar): 2.046445
 - cajsr in component intracellular_ions (millimolar): 1.981290
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008175
 - hf in component INa (dimensionless): 0.659948
 - hs in component INa (dimensionless): 0.659918
 - j in component INa (dimensionless): 0.659745
 - hsp in component INa (dimensionless): 0.411903
 - jp in component INa (dimensionless): 0.659621
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.456358
 - hLp in component INaL (dimensionless): 0.222618
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999463
 - iS in component Ito (dimensionless): 0.534861
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999463
 - iSp in component Ito (dimensionless): 0.578572
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877486
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999619
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003817
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507947
 - xs1 in component IKs (dimensionless): 0.333171
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997029
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
15:09:42 (99236): called boinc_finish(0)

</stderr_txt>
]]>


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