𝕏

Task 55936507

Name HuVeMOp_20240703174051667545_ORdGradInc_k_26-Drouin_MID_4000-conf_443_1
Workunit 26563624
Created 3 Jul 2024, 15:41:46 UTC
Sent 3 Jul 2024, 16:45:05 UTC
Report deadline 6 Jul 2024, 16:45:05 UTC
Received 4 Jul 2024, 22:50:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 1 min 5 sec
CPU time 1 hours 24 min 2 sec
Validate state Valid
Credit 45.80
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Drouin_MID_4000-conf_443.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Drouin_MID_4000-conf_443_1_r997860252_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703174051667545_ORdGradInc_k_26-Drouin_MID_4000-conf_443_1_r997860252_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.664101
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.085874
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031708
     * GKs_b in IKs: 0.001897
     * GK1_b in IK1: 0.163771
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.379139
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035493
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8428642, states[0] = -94.072063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16652058, states[0] = -94.209911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24899407, states[0] = -94.223950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33041437, states[0] = -94.224052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40692204, states[0] = -94.226734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48416807, states[0] = -94.055159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56498197, states[0] = -94.168204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64748193, states[0] = -94.249821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72217698, states[0] = -30.363401, states[40]= 0.006064
Saving checkpoint... 
Iteration: 80589546, states[0] = -94.233475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88451812, states[0] = -94.143872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96695898, states[0] = -94.260691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104911220, states[0] = -94.267778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113183573, states[0] = -94.260964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 122019771, states[0] = 32.835480, states[40]= -0.000000
Saving checkpoint... 
Iteration: 130121097, states[0] = 7.966595, states[40]= 0.000080
Saving checkpoint... 
Iteration: 138784980, states[0] = -94.273810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146697735, states[0] = -94.269712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154564718, states[0] = -94.241126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162941468, states[0] = -94.274424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171579778, states[0] = -94.255462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179779987, states[0] = -94.251736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187887933, states[0] = -94.250197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196221955, states[0] = -36.951715, states[40]= 0.003147
Saving checkpoint... 
Iteration: 204326152, states[0] = -93.859280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212652463, states[0] = -94.266136, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220688066, states[0] = -94.270945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228810257, states[0] = -94.277100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237444900, states[0] = -94.259553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 245121678, states[0] = -94.269690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253415945, states[0] = -94.260265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261250793, states[0] = -94.265207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269279245, states[0] = -94.264228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277238511, states[0] = -94.265483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285477091, states[0] = -94.258375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294756234, states[0] = -94.275377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303224239, states[0] = -94.265703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310847509, states[0] = -94.276551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318871328, states[0] = -94.276250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 326826171, states[0] = -94.276413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334871338, states[0] = -94.276075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343028958, states[0] = -94.271953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351327484, states[0] = -94.261877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360162251, states[0] = -10.583363, states[40]= 0.000704
Saving checkpoint... 
Iteration: 368601391, states[0] = -94.253928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 376650656, states[0] = -94.264538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384943615, states[0] = -94.274049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392779449, states[0] = -94.275044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400934069, states[0] = -94.274105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408401639, states[0] = -94.083149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416684271, states[0] = -94.268719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425963024, states[0] = -94.247540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 433849184, states[0] = -94.249093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442000514, states[0] = -14.612508, states[40]= 0.001883
Saving checkpoint... 
Iteration: 450636786, states[0] = -94.261185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458530741, states[0] = -94.224686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 466918708, states[0] = -94.273692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 475966914, states[0] = -94.246897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 483616757, states[0] = -94.252811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492406506, states[0] = -94.091436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500815293, states[0] = -94.274330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508538086, states[0] = -94.227996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516167073, states[0] = -13.353885, states[40]= 0.000801
Saving checkpoint... 
Iteration: 524035013, states[0] = 33.886117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532262999, states[0] = -70.240431, states[40]= 0.000028
Saving checkpoint... 
Iteration: 540091839, states[0] = 18.665470, states[40]= 0.000006
Saving checkpoint... 
Iteration: 548299752, states[0] = -93.726908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556433411, states[0] = -94.134518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564485458, states[0] = -94.192177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573197289, states[0] = -94.263464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 581467414, states[0] = -94.255204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589887265, states[0] = -94.246660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 598030062, states[0] = 33.934966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605738854, states[0] = -94.248927, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614340301, states[0] = -93.912468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622957344, states[0] = -94.270863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631104861, states[0] = -94.265966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639316517, states[0] = -94.258814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 647564866, states[0] = -94.252027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655270615, states[0] = -94.260070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663865494, states[0] = -94.246112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672014601, states[0] = 31.303825, states[40]= -0.000000
Saving checkpoint... 
Iteration: 680524490, states[0] = -94.218499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688796551, states[0] = -94.271893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697343792, states[0] = -94.257297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705123762, states[0] = -94.264434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713293467, states[0] = -94.258655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721802893, states[0] = -94.246429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 729718711, states[0] = -94.247832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 737484861, states[0] = -94.252905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745011368, states[0] = -94.267784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753477200, states[0] = -94.252911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 761703622, states[0] = -94.247740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770690561, states[0] = -94.265214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778532783, states[0] = -94.221998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786774945, states[0] = -94.270261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794967695, states[0] = -94.268533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803048337, states[0] = -94.265873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811390079, states[0] = -94.254589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819382771, states[0] = -94.254704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827156996, states[0] = -94.261834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834909600, states[0] = -94.269528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843431631, states[0] = -94.253051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 850895447, states[0] = -94.269616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 859286411, states[0] = -94.257146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868553062, states[0] = -94.230876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876344064, states[0] = -93.923011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884423311, states[0] = -94.115506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893322805, states[0] = -94.255607, states[40]= 0.000001
Saving checkpoint... 
Iteration: 901294232, states[0] = -94.256399, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908836350, states[0] = -94.269551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916598858, states[0] = -94.246723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924882314, states[0] = -94.268957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933065831, states[0] = -94.263736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941887198, states[0] = -94.242483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950674159, states[0] = -94.261173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959036510, states[0] = -94.264420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966997489, states[0] = -94.265593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975243663, states[0] = -94.257149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983129947, states[0] = -94.260920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990417008, states[0] = -94.104009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998931276, states[0] = -94.267091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006794870, states[0] = -94.268096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015316463, states[0] = -94.254355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024472643, states[0] = -94.175071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032854435, states[0] = -94.267997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1040837272, states[0] = -94.267984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048584129, states[0] = -94.240654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056848247, states[0] = -94.267753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064054938, states[0] = 30.770161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072002307, states[0] = 24.953296, states[40]= 1.499545
Saving checkpoint... 
Iteration: 1079766433, states[0] = -94.242804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087905556, states[0] = -94.240479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1095690058, states[0] = -94.244037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103309020, states[0] = -94.253539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111438730, states[0] = -94.249677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119766883, states[0] = -94.242321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127917143, states[0] = -94.239837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135508425, states[0] = -94.247586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143834867, states[0] = -94.240891, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151519767, states[0] = -94.247116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159209513, states[0] = -94.256102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168279922, states[0] = -92.567209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176528749, states[0] = -94.215039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184642153, states[0] = -94.253486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1192744310, states[0] = -94.264267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200953348, states[0] = -94.264125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209477644, states[0] = -94.247489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216686313, states[0] = -94.259467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224736633, states[0] = -94.263479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232939625, states[0] = -94.264110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240942034, states[0] = -94.263954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249601728, states[0] = -94.244051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257589108, states[0] = -94.244235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265665294, states[0] = -94.242515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274401401, states[0] = -94.072277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283050944, states[0] = -94.260095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292363423, states[0] = -93.980626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300888275, states[0] = -94.264407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310594280, states[0] = -94.240719, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321696677, states[0] = -94.241228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331588759, states[0] = -94.243365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1341702604, states[0] = -94.240875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351635862, states[0] = -94.242102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361245761, states[0] = -94.252503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371611642, states[0] = -94.242384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381220413, states[0] = -94.253105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390701542, states[0] = -94.258943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400456432, states[0] = -94.153640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410501591, states[0] = -94.194823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420263876, states[0] = -71.284497, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1430370748, states[0] = -93.999529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441920623, states[0] = -94.236060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452284059, states[0] = -93.380381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463090277, states[0] = -94.256609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472046733, states[0] = 32.543457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481534552, states[0] = -94.242844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1490315714, states[0] = -93.797771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498765399, states[0] = -94.261523, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.110279
 - CaMKt in component CaMK (millimolar): 0.002637
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.817940
 - nass in component intracellular_ions (millimolar): 7.818097
 - ki in component intracellular_ions (millimolar): 143.964582
 - kss in component intracellular_ions (millimolar): 143.964566
 - cansr in component intracellular_ions (millimolar): 1.844010
 - cajsr in component intracellular_ions (millimolar): 1.845843
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003919
 - hf in component INa (dimensionless): 0.865572
 - hs in component INa (dimensionless): 0.865572
 - j in component INa (dimensionless): 0.865575
 - hsp in component INa (dimensionless): 0.699231
 - jp in component INa (dimensionless): 0.865577
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707827
 - hLp in component INaL (dimensionless): 0.513344
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.990068
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.995929
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994709
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004569
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009146
 - xs1 in component IKs (dimensionless): 0.054577
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997537
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:15:56 (77874): called boinc_finish(0)

</stderr_txt>
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