𝕏

Task 55935374

Name HuVeMOp_20240630054923063558_ORdGradInc_k_25-Pueyo_APDR-conf_720_2
Workunit 26302177
Created 3 Jul 2024, 15:29:47 UTC
Sent 3 Jul 2024, 16:40:13 UTC
Report deadline 7 Jul 2024, 2:16:13 UTC
Received 4 Jul 2024, 21:04:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240525
Run time 1 hours 50 min 59 sec
CPU time 1 hours 16 min 57 sec
Validate state Valid
Credit 69.77
Device peak FLOPS 7.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054923063558_ORdGradInc_k_25-Pueyo_APDR-conf_720.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054923063558_ORdGradInc_k_25-Pueyo_APDR-conf_720_2_r1873690871_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630054923063558_ORdGradInc_k_25-Pueyo_APDR-conf_720_2_r1873690871_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 113.690987
     * GNaL_b in INaL: 0.007376
     * Gto_b in Ito: 0.085009
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032478
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.147543
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 73.709006
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024611
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10167938, states[0] = -94.459013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21232948, states[0] = -94.862615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31282807, states[0] = -94.903304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41927175, states[0] = -94.966820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52500738, states[0] = 45.121636, states[40]= 0.009675
Saving checkpoint... 
Iteration: 63148495, states[0] = -68.078713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73827852, states[0] = -94.896863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84685019, states[0] = -94.665559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95154708, states[0] = -75.506774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105556676, states[0] = 9.887067, states[40]= 0.004952
Saving checkpoint... 
Iteration: 116901024, states[0] = -94.921206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126611424, states[0] = -27.905519, states[40]= 0.000600
Saving checkpoint... 
Iteration: 136865500, states[0] = -94.905055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148116252, states[0] = -32.347626, states[40]= 0.000385
Saving checkpoint... 
Iteration: 156798883, states[0] = -94.859666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167275737, states[0] = -94.835591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178108159, states[0] = -24.755626, states[40]= 0.000749
Saving checkpoint... 
Iteration: 188517475, states[0] = 22.321316, states[40]= 0.012887
Saving checkpoint... 
Iteration: 199371033, states[0] = -94.905620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209608274, states[0] = -24.843053, states[40]= 0.000745
Saving checkpoint... 
Iteration: 220557061, states[0] = 9.820623, states[40]= 0.004946
Saving checkpoint... 
Iteration: 230511065, states[0] = 23.407714, states[40]= 0.042168
Saving checkpoint... 
Iteration: 241571831, states[0] = 3.263590, states[40]= 0.004628
Saving checkpoint... 
Iteration: 252263484, states[0] = -94.819661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262456153, states[0] = -94.931478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271992925, states[0] = -94.937664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282321715, states[0] = -94.876913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293764299, states[0] = -94.820641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304642534, states[0] = -59.491936, states[40]= 0.000006
Saving checkpoint... 
Iteration: 315699561, states[0] = -94.704911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325472357, states[0] = -94.934399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335391976, states[0] = -94.913703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346463227, states[0] = -94.932745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356583695, states[0] = -3.558785, states[40]= 0.003701
Saving checkpoint... 
Iteration: 367503239, states[0] = 36.616782, states[40]= 0.142470
Saving checkpoint... 
Iteration: 377376054, states[0] = -94.907356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389188749, states[0] = -94.673135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401290630, states[0] = -94.850414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411414272, states[0] = -94.921034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422347617, states[0] = -94.893351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430782449, states[0] = -94.841959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441790582, states[0] = -94.850340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452286365, states[0] = -94.846070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463129719, states[0] = -45.520039, states[40]= 0.000061
Saving checkpoint... 
Iteration: 472488463, states[0] = -94.936854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485126308, states[0] = -42.008401, states[40]= 0.000103
Saving checkpoint... 
Iteration: 497886907, states[0] = -94.911683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510105876, states[0] = -22.607385, states[40]= 0.000847
Saving checkpoint... 
Iteration: 520702537, states[0] = -94.711604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531868309, states[0] = -94.903817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543777991, states[0] = -94.836983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554677131, states[0] = -94.452409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567692074, states[0] = -94.685197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579656349, states[0] = -77.227345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590584222, states[0] = -3.918056, states[40]= 0.003632
Saving checkpoint... 
Iteration: 601091366, states[0] = -9.395981, states[40]= 0.002472
Saving checkpoint... 
Iteration: 610954363, states[0] = -94.930837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622233385, states[0] = -94.773505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632598770, states[0] = -16.009004, states[40]= 0.001347
Saving checkpoint... 
Iteration: 644616053, states[0] = -32.079564, states[40]= 0.000397
Saving checkpoint... 
Iteration: 655328117, states[0] = -94.881133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665801257, states[0] = -94.860203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678598777, states[0] = -16.015454, states[40]= 0.001346
Saving checkpoint... 
Iteration: 690691805, states[0] = -94.684270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702742686, states[0] = -94.789102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714308280, states[0] = -94.866194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726200050, states[0] = -94.705771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737619587, states[0] = -35.423345, states[40]= 0.000262
Saving checkpoint... 
Iteration: 749958012, states[0] = -94.931477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762350634, states[0] = -94.894799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772069343, states[0] = 4.475086, states[40]= 0.004718
Saving checkpoint... 
Iteration: 784178913, states[0] = -94.535934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796615387, states[0] = -31.454356, states[40]= 0.000426
Saving checkpoint... 
Iteration: 806482288, states[0] = -94.935702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819681332, states[0] = -94.601874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831483984, states[0] = -94.935948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840089422, states[0] = -7.795216, states[40]= 0.002816
Saving checkpoint... 
Iteration: 849810252, states[0] = -94.867722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860887435, states[0] = -94.911649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871885554, states[0] = -94.910914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884851322, states[0] = -94.895093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896996619, states[0] = -94.937727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908169900, states[0] = -93.161807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919474673, states[0] = -94.934397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931068104, states[0] = 5.057796, states[40]= 0.004755
Saving checkpoint... 
Iteration: 943108077, states[0] = -24.647876, states[40]= 0.000754
Saving checkpoint... 
Iteration: 954364157, states[0] = -94.901591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964500121, states[0] = -80.051490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975364681, states[0] = -94.901828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987849629, states[0] = -94.894101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999029790, states[0] = 19.534641, states[40]= 0.006133
Saving checkpoint... 
Iteration: 1009964049, states[0] = -94.932462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020807414, states[0] = -94.865274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031782817, states[0] = -94.841959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044042248, states[0] = 15.462490, states[40]= 0.005192
Saving checkpoint... 
Iteration: 1056883696, states[0] = -94.910061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071322106, states[0] = -94.876651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085397554, states[0] = -94.915204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100538175, states[0] = 16.886549, states[40]= 0.005369
Saving checkpoint... 
Iteration: 1113274379, states[0] = -94.832472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126410206, states[0] = -94.919333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140143041, states[0] = -60.063823, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1154513691, states[0] = 22.912855, states[40]= 0.023998
Saving checkpoint... 
Iteration: 1166671325, states[0] = -93.631709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180070111, states[0] = 4.107739, states[40]= 0.004693
Saving checkpoint... 
Iteration: 1193535800, states[0] = 17.680940, states[40]= 0.005517
Saving checkpoint... 
Iteration: 1206624005, states[0] = -39.706581, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1222005717, states[0] = 27.464685, states[40]= 0.137017
Saving checkpoint... 
Iteration: 1234081151, states[0] = -1.903380, states[40]= 0.003995
Saving checkpoint... 
Iteration: 1246794631, states[0] = -94.853737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259023654, states[0] = 21.120183, states[40]= 0.007599
Saving checkpoint... 
Iteration: 1271150166, states[0] = -68.567696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283760701, states[0] = -94.815231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296195283, states[0] = -94.693768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309142784, states[0] = -59.772594, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1322976414, states[0] = -94.934423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336811604, states[0] = -94.868493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349956708, states[0] = -94.930827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363019103, states[0] = 22.046247, states[40]= 0.010661
Saving checkpoint... 
Iteration: 1378529037, states[0] = 19.747927, states[40]= 0.006247
Saving checkpoint... 
Iteration: 1391768136, states[0] = -94.824767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405143535, states[0] = -60.625054, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1418961169, states[0] = -94.931652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430369412, states[0] = -94.903735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444132153, states[0] = -48.095437, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1456921814, states[0] = -94.922518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471629338, states[0] = -45.121127, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1485444887, states[0] = -94.928246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498161013, states[0] = -84.519155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510178738, states[0] = -95.179159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521932311, states[0] = 17.288357, states[40]= 0.006851
Saving checkpoint... 
Iteration: 1533485459, states[0] = -95.061144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544981809, states[0] = -95.221029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557848482, states[0] = -95.192878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572245568, states[0] = -95.194373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585529277, states[0] = 18.143377, states[40]= 0.007282
Saving checkpoint... 
Iteration: 1597694721, states[0] = -95.110149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610621323, states[0] = -95.164204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623379610, states[0] = -13.707223, states[40]= 0.001887
Saving checkpoint... 
Iteration: 1636827287, states[0] = 18.882534, states[40]= 0.007682
Saving checkpoint... 
Iteration: 1650007573, states[0] = 26.086488, states[40]= 0.090456
Saving checkpoint... 
Iteration: 1661069519, states[0] = -95.229957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675121186, states[0] = -95.166035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687362796, states[0] = -95.018758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700131863, states[0] = 17.021236, states[40]= 0.006885
Saving checkpoint... 
Iteration: 1712660276, states[0] = -95.220504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725021204, states[0] = 21.024684, states[40]= 0.010204
Saving checkpoint... 
Iteration: 1736569236, states[0] = -95.046514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748301004, states[0] = -95.127555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760854710, states[0] = -94.893006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775285614, states[0] = -95.091969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788482350, states[0] = -95.083681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801015731, states[0] = 22.090427, states[40]= 0.015373
Saving checkpoint... 
Iteration: 1814144983, states[0] = -66.266176, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1826345599, states[0] = -94.930206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839409642, states[0] = -94.945077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851822247, states[0] = -94.894405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865305622, states[0] = -94.875277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877697338, states[0] = -94.706883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889663049, states[0] = -87.918430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902039684, states[0] = 16.320493, states[40]= 0.005294
Saving checkpoint... 
Iteration: 1913759499, states[0] = -94.815958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926669274, states[0] = -92.951728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939292553, states[0] = -94.852531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952495017, states[0] = -94.937629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962832243, states[0] = -94.883606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977299416, states[0] = -94.858051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989265103, states[0] = -94.820777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001505366, states[0] = 28.209113, states[40]= 0.144175
Saving checkpoint... 
Iteration: 2015477230, states[0] = -94.934179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028575285, states[0] = 1.482867, states[40]= 0.004458
Saving checkpoint... 
Iteration: 2041940277, states[0] = -94.926835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056082233, states[0] = -2.592357, states[40]= 0.003878
Saving checkpoint... 
Iteration: 2070956302, states[0] = -94.930244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083513918, states[0] = 22.877238, states[40]= 0.022958
Saving checkpoint... 
Iteration: 2097061043, states[0] = 8.179974, states[40]= 0.004898
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.813223
 - CaMKt in component CaMK (millimolar): 0.007159
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.519959
 - nass in component intracellular_ions (millimolar): 6.520021
 - ki in component intracellular_ions (millimolar): 145.454996
 - kss in component intracellular_ions (millimolar): 145.454975
 - cansr in component intracellular_ions (millimolar): 1.323829
 - cajsr in component intracellular_ions (millimolar): 1.285367
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003651
 - hf in component INa (dimensionless): 0.878454
 - hs in component INa (dimensionless): 0.878449
 - j in component INa (dimensionless): 0.878416
 - hsp in component INa (dimensionless): 0.722919
 - jp in component INa (dimensionless): 0.878394
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706596
 - hLp in component INaL (dimensionless): 0.446461
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.617188
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.690857
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931802
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999875
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001656
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343896
 - xs1 in component IKs (dimensionless): 0.247845
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997360
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:34:03 (345443): called boinc_finish(0)

</stderr_txt>
]]>


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