𝕏

Task 55929803

Name HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1
Workunit 26560357
Created 3 Jul 2024, 14:24:39 UTC
Sent 3 Jul 2024, 16:09:41 UTC
Report deadline 7 Jul 2024, 1:45:41 UTC
Received 4 Jul 2024, 11:21:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241121
Run time 2 hours 24 min 56 sec
CPU time 1 hours 2 min 46 sec
Validate state Valid
Credit 59.50
Device peak FLOPS 5.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.38 MB
Peak swap size 5.29 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.655062
     * GNaL_b in INaL: 0.005595
     * Gto_b in Ito: 0.085339
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031911
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.167859
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.600437
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036601
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10848898, states[0] = -95.079359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18439829, states[0] = -95.085427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26227204, states[0] = -94.937354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33714089, states[0] = -94.904980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40293612, states[0] = -94.993371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48306182, states[0] = -94.996137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56708989, states[0] = -94.876585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65656232, states[0] = -87.735313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73280533, states[0] = -94.963857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80542553, states[0] = 13.964802, states[40]= 0.005155
Saving checkpoint... 
Iteration: 88820511, states[0] = -94.989455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95253126, states[0] = -94.930304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103545434, states[0] = 12.943435, states[40]= 0.005068
Saving checkpoint... 
Iteration: 111490783, states[0] = -95.036880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119429212, states[0] = -95.026109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127625969, states[0] = -46.120692, states[40]= 0.000050
Saving checkpoint... 
Iteration: 135753862, states[0] = -94.927261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143472172, states[0] = -95.032340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150918977, states[0] = -95.022164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158656388, states[0] = -86.471235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166295013, states[0] = -94.965943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174237286, states[0] = -94.904729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181987615, states[0] = -95.033489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190288561, states[0] = -94.960404, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.655062
     * GNaL_b in INaL: 0.005595
     * Gto_b in Ito: 0.085339
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031911
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.167859
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.600437
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036601
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 190288561
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.960404 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 224913232, states[0] = -95.019782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232800357, states[0] = -94.969357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240577572, states[0] = -1.740928, states[40]= 0.003991
Saving checkpoint... 
Iteration: 249535173, states[0] = 16.735436, states[40]= 0.005557
Saving checkpoint... 
Iteration: 257958831, states[0] = -95.028949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266832030, states[0] = -94.989279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275540035, states[0] = 15.024882, states[40]= 0.005257
Saving checkpoint... 
Iteration: 284240129, states[0] = -94.908057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291352083, states[0] = -94.999055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297919881, states[0] = -95.021237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306108252, states[0] = -28.420141, states[40]= 0.000533
Saving checkpoint... 
Iteration: 314120679, states[0] = -40.518119, states[40]= 0.000117
Saving checkpoint... 
Iteration: 321648519, states[0] = -72.931727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329382862, states[0] = -95.010849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337272257, states[0] = -94.945273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345610609, states[0] = -30.677125, states[40]= 0.000427
Saving checkpoint... 
Iteration: 353935400, states[0] = -95.024576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361841624, states[0] = -94.994117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370627285, states[0] = -47.358129, states[40]= 0.000041
Saving checkpoint... 
Iteration: 379012364, states[0] = 22.361188, states[40]= 0.031211
Saving checkpoint... 
Iteration: 387866327, states[0] = -95.004883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396310938, states[0] = -94.976550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404660302, states[0] = -91.404897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413074595, states[0] = 0.029114, states[40]= 0.004249
Saving checkpoint... 
Iteration: 421892285, states[0] = -95.013772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430424530, states[0] = -95.022206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439678128, states[0] = -94.784535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446979444, states[0] = -95.031840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454090373, states[0] = -11.504361, states[40]= 0.002038
Saving checkpoint... 
Iteration: 460828861, states[0] = -94.987389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468496530, states[0] = -95.033945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477190884, states[0] = -94.823104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486093979, states[0] = -14.827869, states[40]= 0.001488
Saving checkpoint... 
Iteration: 494942240, states[0] = -95.025829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503609946, states[0] = -30.040965, states[40]= 0.000456
Saving checkpoint... 
Iteration: 509704966, states[0] = -94.850983, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_424_1_r1071174381_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.655062
     * GNaL_b in INaL: 0.005595
     * Gto_b in Ito: 0.085339
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031911
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.167859
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.600437
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036601
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 509704966
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.850983 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 542532320, states[0] = 17.679303, states[40]= 0.005821
Saving checkpoint... 
Iteration: 547842417, states[0] = -94.994385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554501618, states[0] = 47.811162, states[40]= 0.065149
Saving checkpoint... 
Iteration: 560811061, states[0] = -94.976528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566500946, states[0] = 47.987182, states[40]= 0.022549
Saving checkpoint... 
Iteration: 573695839, states[0] = -94.833204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580218320, states[0] = -94.874737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592798655, states[0] = -94.967770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598372966, states[0] = -95.007241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602751337, states[0] = -94.922249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608048326, states[0] = 11.904219, states[40]= 0.005003
Saving checkpoint... 
Iteration: 614874499, states[0] = -95.007784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621185148, states[0] = -94.810124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626402122, states[0] = -95.016492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631645300, states[0] = -68.259728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637431040, states[0] = -95.023493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643751263, states[0] = -94.922134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650123090, states[0] = -42.968945, states[40]= 0.000081
Saving checkpoint... 
Iteration: 656370901, states[0] = -95.006447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662653597, states[0] = -81.511565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669412572, states[0] = -95.019218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675140649, states[0] = -62.313778, states[40]= 0.000003
Saving checkpoint... 
Iteration: 679932457, states[0] = -95.023764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697996844, states[0] = -95.033837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733692855, states[0] = -94.827041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766754154, states[0] = -94.925517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799796481, states[0] = -94.965994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832321412, states[0] = -94.982866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865317750, states[0] = -94.980618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898247599, states[0] = -94.917438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929008718, states[0] = 23.504890, states[40]= 0.071691
Saving checkpoint... 
Iteration: 961540586, states[0] = 14.824737, states[40]= 0.005232
Saving checkpoint... 
Iteration: 992858107, states[0] = -95.001194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025564415, states[0] = 5.188487, states[40]= 0.004724
Saving checkpoint... 
Iteration: 1059225358, states[0] = -94.885892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092622686, states[0] = -42.554250, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1120907761, states[0] = -95.017701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142413667, states[0] = -95.019195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167573251, states[0] = 0.780240, states[40]= 0.004343
Saving checkpoint... 
Iteration: 1195892636, states[0] = -95.013393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226120983, states[0] = -40.823271, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1257833483, states[0] = -94.989399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290911914, states[0] = -95.018663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324404481, states[0] = -95.016700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357117880, states[0] = -37.729587, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1389929957, states[0] = -95.022792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420486676, states[0] = -95.032170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453036998, states[0] = 16.108001, states[40]= 0.005426
Saving checkpoint... 
Iteration: 1485045858, states[0] = 12.853439, states[40]= 0.005056
Saving checkpoint... 
Iteration: 1516868817, states[0] = -4.102121, states[40]= 0.003977
Saving checkpoint... 
Iteration: 1548258305, states[0] = -95.258180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582844833, states[0] = 9.931107, states[40]= 0.005793
Saving checkpoint... 
Iteration: 1616736081, states[0] = 14.185250, states[40]= 0.006369
Saving checkpoint... 
Iteration: 1646730753, states[0] = 16.562477, states[40]= 0.006985
Saving checkpoint... 
Iteration: 1673724993, states[0] = 18.874057, states[40]= 0.008281
Saving checkpoint... 
Iteration: 1701612653, states[0] = 22.762789, states[40]= 0.030858
Saving checkpoint... 
Iteration: 1729551167, states[0] = 6.439918, states[40]= 0.005496
Saving checkpoint... 
Iteration: 1754637612, states[0] = -95.251524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782964422, states[0] = -2.040677, states[40]= 0.004440
Saving checkpoint... 
Iteration: 1809545667, states[0] = 12.111583, states[40]= 0.005080
Saving checkpoint... 
Iteration: 1836204585, states[0] = -94.872844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863627761, states[0] = -48.638359, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1888755504, states[0] = -94.931311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916933485, states[0] = -95.025274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942098512, states[0] = -19.189899, states[40]= 0.001021
Saving checkpoint... 
Iteration: 1970787644, states[0] = -94.958571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000338093, states[0] = -94.991455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030551372, states[0] = 10.708583, states[40]= 0.004951
Saving checkpoint... 
Iteration: 2060962547, states[0] = -95.028346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092564014, states[0] = 5.371904, states[40]= 0.004734
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909145
 - CaMKt in component CaMK (millimolar): 0.006907
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.613713
 - nass in component intracellular_ions (millimolar): 6.613773
 - ki in component intracellular_ions (millimolar): 145.364885
 - kss in component intracellular_ions (millimolar): 145.364865
 - cansr in component intracellular_ions (millimolar): 1.307708
 - cajsr in component intracellular_ions (millimolar): 1.269932
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880127
 - hs in component INa (dimensionless): 0.880123
 - j in component INa (dimensionless): 0.880095
 - hsp in component INa (dimensionless): 0.726070
 - jp in component INa (dimensionless): 0.880077
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710534
 - hLp in component INaL (dimensionless): 0.453495
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622888
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698171
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936679
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001584
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329072
 - xs1 in component IKs (dimensionless): 0.238773
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:58:31 (17452): called boinc_finish(0)

</stderr_txt>
]]>


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