𝕏

Task 55929680

Name HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_419_0
Workunit 26560296
Created 3 Jul 2024, 14:24:34 UTC
Sent 3 Jul 2024, 16:13:26 UTC
Report deadline 7 Jul 2024, 1:49:26 UTC
Received 5 Jul 2024, 0:04:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224229
Run time 3 hours 1 min 22 sec
CPU time 2 hours 17 min 14 sec
Validate state Valid
Credit 65.60
Device peak FLOPS 5.85 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.13 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_419.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_419_0_r1340088430_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_419_0_r1340088430_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.421426
     * GNaL_b in INaL: 0.005585
     * Gto_b in Ito: 0.082060
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031770
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.166137
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.461856
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037172
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13381232, states[0] = -95.126693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26768944, states[0] = -95.024861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40532988, states[0] = 17.242926, states[40]= 0.005787
Saving checkpoint... 
Iteration: 55276519, states[0] = -94.998160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69338914, states[0] = -95.033771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82732801, states[0] = -94.933647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96140880, states[0] = -62.804446, states[40]= 0.000003
Saving checkpoint... 
Iteration: 109306796, states[0] = -95.004535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120390563, states[0] = -95.042945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133561211, states[0] = 6.741995, states[40]= 0.004824
Saving checkpoint... 
Iteration: 146023841, states[0] = 20.371616, states[40]= 0.007615
Saving checkpoint... 
Iteration: 159206236, states[0] = -94.880350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173202587, states[0] = -94.873083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188195292, states[0] = -94.858466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203143557, states[0] = -65.566939, states[40]= 0.000002
Saving checkpoint... 
Iteration: 217423467, states[0] = -95.048645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231547455, states[0] = 12.423588, states[40]= 0.005053
Saving checkpoint... 
Iteration: 245681155, states[0] = -94.823515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259872614, states[0] = -95.033671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274260167, states[0] = -94.958726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288560919, states[0] = 6.916224, states[40]= 0.004830
Saving checkpoint... 
Iteration: 302718994, states[0] = -94.901847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317110593, states[0] = -30.355887, states[40]= 0.000442
Saving checkpoint... 
Iteration: 331122551, states[0] = -42.100616, states[40]= 0.000093
Saving checkpoint... 
Iteration: 345166422, states[0] = -94.177914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358946287, states[0] = -95.053061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372967591, states[0] = -95.056612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386888978, states[0] = -95.039098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400594502, states[0] = -15.014425, states[40]= 0.001464
Saving checkpoint... 
Iteration: 415316959, states[0] = -95.006590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429634834, states[0] = -55.251477, states[40]= 0.000011
Saving checkpoint... 
Iteration: 442223348, states[0] = -94.908900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454200254, states[0] = -94.867708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466340716, states[0] = -95.019838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477975830, states[0] = -95.057743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490755851, states[0] = -94.953647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503123157, states[0] = -42.720141, states[40]= 0.000084
Saving checkpoint... 
Iteration: 515673928, states[0] = -94.756915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527910621, states[0] = -95.045164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540390619, states[0] = -95.039514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553568209, states[0] = 3.559483, states[40]= 0.004626
Saving checkpoint... 
Iteration: 567431700, states[0] = -95.050053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581079592, states[0] = -2.820036, states[40]= 0.003814
Saving checkpoint... 
Iteration: 594290439, states[0] = -94.987460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607159150, states[0] = -89.780711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620015785, states[0] = 22.100677, states[40]= 0.016428
Saving checkpoint... 
Iteration: 633244801, states[0] = -94.939949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646557127, states[0] = 8.537315, states[40]= 0.004895
Saving checkpoint... 
Iteration: 659329734, states[0] = -95.013963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672882585, states[0] = -95.036852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685474198, states[0] = -95.057386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697416755, states[0] = -95.046591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708359367, states[0] = -95.028173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720265753, states[0] = -94.964459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731848868, states[0] = -95.023571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742697780, states[0] = -94.862664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754794004, states[0] = -94.990222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766518290, states[0] = 21.632854, states[40]= 0.011713
Saving checkpoint... 
Iteration: 777706019, states[0] = -94.878520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789951418, states[0] = -95.053718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802518422, states[0] = 21.606853, states[40]= 0.011540
Saving checkpoint... 
Iteration: 814469181, states[0] = -95.056578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827241758, states[0] = -94.935804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839059731, states[0] = 7.432031, states[40]= 0.004852
Saving checkpoint... 
Iteration: 851292046, states[0] = -94.988605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862848694, states[0] = -95.023411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873710038, states[0] = -94.885859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885721830, states[0] = -94.906165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899798656, states[0] = -94.993714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913341325, states[0] = -95.019866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924143652, states[0] = -65.661097, states[40]= 0.000002
Saving checkpoint... 
Iteration: 937771722, states[0] = -94.970409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951393287, states[0] = -95.040078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964862854, states[0] = -95.029441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977250402, states[0] = -94.946828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988184519, states[0] = -94.833652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998955238, states[0] = -95.054250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010324032, states[0] = -95.010506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022962636, states[0] = -95.055447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034743088, states[0] = -94.937451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044750550, states[0] = -94.946969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053370214, states[0] = -95.032244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063070932, states[0] = 2.191896, states[40]= 0.004505
Saving checkpoint... 
Iteration: 1073058566, states[0] = 7.930437, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1083569489, states[0] = 2.926127, states[40]= 0.004574
Saving checkpoint... 
Iteration: 1093717958, states[0] = -94.899600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104277271, states[0] = -94.975639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114965723, states[0] = -95.055872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125151304, states[0] = -76.891774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136285859, states[0] = -94.983299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147026659, states[0] = 19.635840, states[40]= 0.006781
Saving checkpoint... 
Iteration: 1158288188, states[0] = -94.985255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169555657, states[0] = 9.148537, states[40]= 0.004917
Saving checkpoint... 
Iteration: 1180073090, states[0] = 1.048906, states[40]= 0.004384
Saving checkpoint... 
Iteration: 1190175441, states[0] = -94.781513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199859030, states[0] = -95.027732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209379234, states[0] = -95.035389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218005229, states[0] = 28.109287, states[40]= 0.140539
Saving checkpoint... 
Iteration: 1227670592, states[0] = -94.640781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237513238, states[0] = 22.561525, states[40]= 0.025904
Saving checkpoint... 
Iteration: 1250037681, states[0] = 16.082544, states[40]= 0.005426
Saving checkpoint... 
Iteration: 1261836275, states[0] = -95.017097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273706905, states[0] = -94.879865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285205830, states[0] = -94.877853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296714682, states[0] = -94.893850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308140796, states[0] = -62.118683, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1319073537, states[0] = 0.804707, states[40]= 0.004355
Saving checkpoint... 
Iteration: 1330088480, states[0] = -9.553970, states[40]= 0.002428
Saving checkpoint... 
Iteration: 1340798909, states[0] = -94.993634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351282718, states[0] = -94.980436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362044608, states[0] = 13.520454, states[40]= 0.005125
Saving checkpoint... 
Iteration: 1372847738, states[0] = -95.022657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383832565, states[0] = -95.015063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394200480, states[0] = -94.867568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404523126, states[0] = 20.566058, states[40]= 0.007910
Saving checkpoint... 
Iteration: 1415337777, states[0] = -95.017776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426210753, states[0] = -94.886810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436628217, states[0] = -48.023626, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1446766112, states[0] = -94.964389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456902693, states[0] = -95.042485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466907395, states[0] = -95.043750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478083186, states[0] = -5.318568, states[40]= 0.003329
Saving checkpoint... 
Iteration: 1489582748, states[0] = -4.997957, states[40]= 0.003395
Saving checkpoint... 
Iteration: 1500110463, states[0] = -35.807207, states[40]= 0.000217
Saving checkpoint... 
Iteration: 1510652047, states[0] = -94.974085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521438656, states[0] = -90.198731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531932905, states[0] = -81.701794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542240769, states[0] = -95.265275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552812037, states[0] = 23.387776, states[40]= 0.034637
Saving checkpoint... 
Iteration: 1563937168, states[0] = 13.973809, states[40]= 0.006316
Saving checkpoint... 
Iteration: 1574574758, states[0] = -95.165932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585122681, states[0] = -95.256316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596044119, states[0] = 10.448238, states[40]= 0.005859
Saving checkpoint... 
Iteration: 1606951681, states[0] = -95.070137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617712622, states[0] = -53.694897, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1628885960, states[0] = -95.196340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640173429, states[0] = -9.689570, states[40]= 0.002712
Saving checkpoint... 
Iteration: 1651788567, states[0] = -95.326137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662396738, states[0] = -35.159407, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1673100632, states[0] = 38.641071, states[40]= 0.002404
Saving checkpoint... 
Iteration: 1683705484, states[0] = -45.139000, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1694267231, states[0] = -95.153964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704715865, states[0] = -57.877804, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1715338567, states[0] = -95.281302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726109640, states[0] = -95.241205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736807756, states[0] = -47.856576, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1747164358, states[0] = -95.307697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757772958, states[0] = -9.250756, states[40]= 0.002815
Saving checkpoint... 
Iteration: 1768606708, states[0] = -46.602694, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1778732231, states[0] = 16.116487, states[40]= 0.006828
Saving checkpoint... 
Iteration: 1789606384, states[0] = -46.217068, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1800375567, states[0] = -95.113431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810184539, states[0] = -94.875739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820221517, states[0] = -94.941328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831316450, states[0] = -95.032215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842313644, states[0] = -95.023063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853002853, states[0] = 38.153564, states[40]= 0.129182
Saving checkpoint... 
Iteration: 1863480408, states[0] = -95.067822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874240092, states[0] = -94.940546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884817434, states[0] = -95.011470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894933318, states[0] = -95.053607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905340336, states[0] = -95.021729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916446028, states[0] = -95.054169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927526310, states[0] = 19.715576, states[40]= 0.006862
Saving checkpoint... 
Iteration: 1938502157, states[0] = 43.399345, states[40]= 0.096185
Saving checkpoint... 
Iteration: 1949143177, states[0] = -65.132134, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1960256684, states[0] = -94.954263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971238756, states[0] = -94.931395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983306295, states[0] = -94.998833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994654879, states[0] = -83.187417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005597863, states[0] = -18.209507, states[40]= 0.001103
Saving checkpoint... 
Iteration: 2016643083, states[0] = -64.945358, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2027076096, states[0] = -0.652390, states[40]= 0.004163
Saving checkpoint... 
Iteration: 2037606185, states[0] = -26.140428, states[40]= 0.000642
Saving checkpoint... 
Iteration: 2048428630, states[0] = -95.048483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059046727, states[0] = 12.707287, states[40]= 0.005069
Saving checkpoint... 
Iteration: 2069439260, states[0] = -95.050647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079837157, states[0] = -95.017017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090162316, states[0] = -92.639638, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.935604
 - CaMKt in component CaMK (millimolar): 0.006860
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.533554
 - nass in component intracellular_ions (millimolar): 6.533614
 - ki in component intracellular_ions (millimolar): 145.445787
 - kss in component intracellular_ions (millimolar): 145.445768
 - cansr in component intracellular_ions (millimolar): 1.304919
 - cajsr in component intracellular_ions (millimolar): 1.267155
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003606
 - hf in component INa (dimensionless): 0.880585
 - hs in component INa (dimensionless): 0.880581
 - j in component INa (dimensionless): 0.880553
 - hsp in component INa (dimensionless): 0.726934
 - jp in component INa (dimensionless): 0.880535
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711127
 - hLp in component INaL (dimensionless): 0.453963
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622656
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697824
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935885
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001577
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329404
 - xs1 in component IKs (dimensionless): 0.239773
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997328
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:58:59 (914848): called boinc_finish(0)

</stderr_txt>
]]>


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