𝕏

Task 55929395

Name HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1
Workunit 26560153
Created 3 Jul 2024, 14:24:24 UTC
Sent 3 Jul 2024, 16:03:58 UTC
Report deadline 7 Jul 2024, 1:39:58 UTC
Received 3 Jul 2024, 20:30:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 2 hours 54 min 43 sec
CPU time 1 hours 39 min 15 sec
Validate state Valid
Credit 65.93
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.86 MB
Peak swap size 391.76 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.256239
     * GNaL_b in INaL: 0.005735
     * Gto_b in Ito: 0.082684
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032152
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.164019
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.989507
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 871622, states[0] = -95.110348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46955053, states[0] = -95.033697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77818497, states[0] = -94.970710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99910410, states[0] = -95.004019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121764287, states[0] = -94.918290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143981188, states[0] = -95.013720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163208185, states[0] = -94.834821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182495626, states[0] = -95.014550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204019138, states[0] = 21.379648, states[40]= 0.010704
Saving checkpoint... 
Iteration: 226150347, states[0] = -76.048984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247606461, states[0] = -26.878829, states[40]= 0.000607
Saving checkpoint... 
Iteration: 268857161, states[0] = -94.980779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290243831, states[0] = -94.890797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311381149, states[0] = -94.989957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330159981, states[0] = -90.992141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351803546, states[0] = -94.950425, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.256239
     * GNaL_b in INaL: 0.005735
     * Gto_b in Ito: 0.082684
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032152
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.164019
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.989507
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 351803546
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.950425 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 386563837, states[0] = 5.464556, states[40]= 0.004765


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.256239
     * GNaL_b in INaL: 0.005735
     * Gto_b in Ito: 0.082684
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032152
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.164019
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.989507
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 386563837
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 5.464556 (After loading)
 - states[40]: 0.004765 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 431840466, states[0] = -94.972849, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162412227155_ORdGradInc_k_26-Pueyo_APDR-conf_509_1_r1863627776_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.256239
     * GNaL_b in INaL: 0.005735
     * Gto_b in Ito: 0.082684
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032152
     * GKs_b in IKs: 0.001963
     * GK1_b in IK1: 0.164019
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.989507
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035967
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 431840466
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.972849 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 486515774, states[0] = 22.024867, states[40]= 0.016494
Saving checkpoint... 
Iteration: 514477203, states[0] = -95.011535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534765607, states[0] = -94.916696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553078626, states[0] = -2.449992, states[40]= 0.003889
Saving checkpoint... 
Iteration: 573563314, states[0] = 5.703481, states[40]= 0.004778
Saving checkpoint... 
Iteration: 594109343, states[0] = -29.638918, states[40]= 0.000475
Saving checkpoint... 
Iteration: 614289672, states[0] = -94.939439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634835594, states[0] = -94.970202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655564078, states[0] = 5.353950, states[40]= 0.004758
Saving checkpoint... 
Iteration: 676528892, states[0] = 18.900424, states[40]= 0.006342
Saving checkpoint... 
Iteration: 696961686, states[0] = -95.009093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717970178, states[0] = -95.010397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738232736, states[0] = -94.874826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758906078, states[0] = -94.997287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779749395, states[0] = -94.897697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800108582, states[0] = -28.907915, states[40]= 0.000510
Saving checkpoint... 
Iteration: 820908796, states[0] = -94.997977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841337467, states[0] = -94.971058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861850374, states[0] = -94.977358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882607653, states[0] = -28.016627, states[40]= 0.000552
Saving checkpoint... 
Iteration: 902835954, states[0] = -94.970227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924450935, states[0] = -95.007128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945084461, states[0] = -6.603206, states[40]= 0.003066
Saving checkpoint... 
Iteration: 965197039, states[0] = -94.811864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985035988, states[0] = 16.585366, states[40]= 0.005546
Saving checkpoint... 
Iteration: 1005086220, states[0] = -8.014608, states[40]= 0.002762
Saving checkpoint... 
Iteration: 1025467949, states[0] = -95.009872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045423512, states[0] = -95.001475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065660069, states[0] = -91.074636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084795805, states[0] = -94.944117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105564640, states[0] = 5.094323, states[40]= 0.004743
Saving checkpoint... 
Iteration: 1126316701, states[0] = -94.958903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146657776, states[0] = -88.394852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166799620, states[0] = -94.947007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186645464, states[0] = -68.733576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207023644, states[0] = 20.353287, states[40]= 0.007696
Saving checkpoint... 
Iteration: 1228001666, states[0] = 47.323054, states[40]= 0.068769
Saving checkpoint... 
Iteration: 1246138632, states[0] = -60.198223, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1268112878, states[0] = -33.046618, states[40]= 0.000326
Saving checkpoint... 
Iteration: 1288365157, states[0] = -94.983426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308887868, states[0] = -94.991562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328936228, states[0] = -95.004064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349078284, states[0] = -2.229979, states[40]= 0.003926
Saving checkpoint... 
Iteration: 1369436971, states[0] = -95.004191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390087846, states[0] = -9.382063, states[40]= 0.002470
Saving checkpoint... 
Iteration: 1410646689, states[0] = -70.442462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429579719, states[0] = -3.168295, states[40]= 0.003761
Saving checkpoint... 
Iteration: 1450569798, states[0] = 2.588966, states[40]= 0.004553
Saving checkpoint... 
Iteration: 1469001905, states[0] = 45.589892, states[40]= 0.082343
Saving checkpoint... 
Iteration: 1490015285, states[0] = 22.113035, states[40]= 0.017855
Saving checkpoint... 
Iteration: 1509064960, states[0] = -0.820186, states[40]= 0.004582
Saving checkpoint... 
Iteration: 1530760557, states[0] = -95.062391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550803916, states[0] = -42.922784, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1571352135, states[0] = -95.246965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591650380, states[0] = -94.997825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611864758, states[0] = -95.264595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633112015, states[0] = -95.201564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650707877, states[0] = -48.493233, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1675753117, states[0] = -95.255204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698636769, states[0] = 13.930771, states[40]= 0.006356
Saving checkpoint... 
Iteration: 1721536665, states[0] = -90.784160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742405724, states[0] = 28.242853, states[40]= 0.118654
Saving checkpoint... 
Iteration: 1767192624, states[0] = -95.167803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789697170, states[0] = -95.176586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812672441, states[0] = -94.770898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835206150, states[0] = -94.854005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858814244, states[0] = -94.969131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882011511, states[0] = 22.812931, states[40]= 0.037421
Saving checkpoint... 
Iteration: 1905541335, states[0] = 14.607586, states[40]= 0.005245
Saving checkpoint... 
Iteration: 1928693285, states[0] = -94.805108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950342207, states[0] = -94.973555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975104155, states[0] = -24.690804, states[40]= 0.000710
Saving checkpoint... 
Iteration: 1998544176, states[0] = 13.578883, states[40]= 0.005143
Saving checkpoint... 
Iteration: 2021770817, states[0] = -94.921243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045232460, states[0] = -94.873599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066370333, states[0] = -94.984933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091031669, states[0] = 18.035907, states[40]= 0.005951
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.889244
 - CaMKt in component CaMK (millimolar): 0.006882
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.598051
 - nass in component intracellular_ions (millimolar): 6.598110
 - ki in component intracellular_ions (millimolar): 145.380734
 - kss in component intracellular_ions (millimolar): 145.380715
 - cansr in component intracellular_ions (millimolar): 1.307283
 - cajsr in component intracellular_ions (millimolar): 1.269571
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879782
 - hs in component INa (dimensionless): 0.879777
 - j in component INa (dimensionless): 0.879749
 - hsp in component INa (dimensionless): 0.725419
 - jp in component INa (dimensionless): 0.879731
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710012
 - hLp in component INaL (dimensionless): 0.452902
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622904
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.698080
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936347
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001585
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330098
 - xs1 in component IKs (dimensionless): 0.238759
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:28:31 (7613): called boinc_finish(0)

</stderr_txt>
]]>