𝕏

Task 55927204

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Drouin_EPI_3000-conf_878_0
Workunit 26559059
Created 3 Jul 2024, 14:23:17 UTC
Sent 3 Jul 2024, 15:49:38 UTC
Report deadline 6 Jul 2024, 15:49:38 UTC
Received 4 Jul 2024, 22:50:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 4 min 29 sec
CPU time 1 hours 23 min 46 sec
Validate state Valid
Credit 45.32
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Drouin_EPI_3000-conf_878.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Drouin_EPI_3000-conf_878_0_r1350695879_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Drouin_EPI_3000-conf_878_0_r1350695879_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.074724
     * GNaL_b in INaL: 0.005686
     * Gto_b in Ito: 0.083768
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032042
     * GKs_b in IKs: 0.001957
     * GK1_b in IK1: 0.164112
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.821394
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035984
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8487357, states[0] = -94.399749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16359191, states[0] = -94.337143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24851596, states[0] = -94.328068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32802133, states[0] = -94.298300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40813199, states[0] = -94.132154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49429069, states[0] = -94.288753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57584042, states[0] = -94.316980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65799313, states[0] = -94.297309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73560641, states[0] = 21.817744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81498094, states[0] = -94.312082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89914577, states[0] = -94.301281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98766899, states[0] = -94.308399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107916115, states[0] = -94.305201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116023496, states[0] = -94.325463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124838767, states[0] = -94.199629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133339583, states[0] = -94.310834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141369061, states[0] = -94.243560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149414339, states[0] = -94.329702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157007878, states[0] = -94.325541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165962280, states[0] = -94.327961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173898730, states[0] = -94.310660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182196336, states[0] = -94.339117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190044458, states[0] = -94.324407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197461731, states[0] = -94.328294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205152773, states[0] = -94.319696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213213301, states[0] = -93.715642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221057289, states[0] = -94.334185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229909798, states[0] = -94.282784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238330728, states[0] = -94.312747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246237596, states[0] = -93.872019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254422371, states[0] = -94.329696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262661658, states[0] = -63.310719, states[40]= 0.000017
Saving checkpoint... 
Iteration: 270938411, states[0] = -94.328686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278599577, states[0] = -94.321121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286667556, states[0] = -71.086192, states[40]= 0.000006
Saving checkpoint... 
Iteration: 295658755, states[0] = -59.817300, states[40]= 0.000027
Saving checkpoint... 
Iteration: 303983229, states[0] = -94.326033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311982354, states[0] = -94.306945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320167417, states[0] = -94.337942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328029966, states[0] = -94.323456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336036828, states[0] = 26.024847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343943405, states[0] = -94.301569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351276855, states[0] = -94.047415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359218954, states[0] = -94.336569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367577217, states[0] = 14.981770, states[40]= 0.000010
Saving checkpoint... 
Iteration: 375698373, states[0] = -94.336726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384239134, states[0] = -93.878403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392489698, states[0] = -94.324267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400163529, states[0] = -94.316444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409054148, states[0] = -94.321002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417857042, states[0] = -94.330196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425938569, states[0] = -94.306332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434617885, states[0] = -94.317772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442603290, states[0] = 0.098395, states[40]= 0.000171
Saving checkpoint... 
Iteration: 450806174, states[0] = -94.331946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459736387, states[0] = -94.334408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468164515, states[0] = -66.918238, states[40]= 0.000010
Saving checkpoint... 
Iteration: 476247939, states[0] = -94.333769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484798015, states[0] = -94.110678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493437862, states[0] = -94.305225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501406590, states[0] = -94.276056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509489199, states[0] = -94.322333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517630031, states[0] = -26.464013, states[40]= 0.000370
Saving checkpoint... 
Iteration: 525294607, states[0] = -94.100549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533823745, states[0] = -94.308205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542160820, states[0] = -94.334238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550341257, states[0] = -94.307336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558866938, states[0] = -94.327370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566491934, states[0] = -94.321246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574205339, states[0] = -94.311858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582525396, states[0] = -94.323707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591503181, states[0] = -94.318840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600195704, states[0] = -93.554852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608522768, states[0] = -94.319101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616874474, states[0] = -94.244547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625072675, states[0] = -94.316558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632990169, states[0] = -94.301360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641239868, states[0] = -94.331272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648761719, states[0] = -94.330413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657002936, states[0] = 16.039286, states[40]= 1.526920
Saving checkpoint... 
Iteration: 665528445, states[0] = -94.317888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674055697, states[0] = -94.326711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682619806, states[0] = -15.334962, states[40]= 0.000243
Saving checkpoint... 
Iteration: 690792900, states[0] = -94.328496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699600063, states[0] = -94.330037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707770693, states[0] = -94.307165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716461004, states[0] = -94.320214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724907045, states[0] = -94.272652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733718160, states[0] = -93.741438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742072715, states[0] = -94.314599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750128829, states[0] = -25.154689, states[40]= 0.000347
Saving checkpoint... 
Iteration: 759294255, states[0] = -94.095585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766946575, states[0] = -94.296044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775544004, states[0] = 25.404403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783254031, states[0] = -93.947416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791135812, states[0] = -94.329807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799500546, states[0] = 8.555239, states[40]= 0.006799
Saving checkpoint... 
Iteration: 806924928, states[0] = -94.300361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815468783, states[0] = -94.318183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823673119, states[0] = -79.945033, states[40]= 0.000002
Saving checkpoint... 
Iteration: 832307499, states[0] = -94.303769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840309024, states[0] = -94.132633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848263998, states[0] = -94.326994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856570106, states[0] = 18.064522, states[40]= 0.000004
Saving checkpoint... 
Iteration: 864847723, states[0] = -94.323161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872706176, states[0] = -94.306833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880628106, states[0] = -24.368695, states[40]= 0.000332
Saving checkpoint... 
Iteration: 888984565, states[0] = -94.316200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896981205, states[0] = -94.297187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905676445, states[0] = -94.307455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913465979, states[0] = -94.297351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921555777, states[0] = -94.322579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928889711, states[0] = -94.254694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937073145, states[0] = -94.311310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944872671, states[0] = -94.299690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952414703, states[0] = -94.298235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960436379, states[0] = -94.287591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968760419, states[0] = -94.303168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976719189, states[0] = -93.744331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984162789, states[0] = -64.691876, states[40]= 0.000014
Saving checkpoint... 
Iteration: 992544816, states[0] = -94.311660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000574503, states[0] = 16.208781, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1008270049, states[0] = -94.011265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016704265, states[0] = -94.304490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024834326, states[0] = -94.181387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032467761, states[0] = -94.300629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040443490, states[0] = -94.315630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048198312, states[0] = -94.304194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056629223, states[0] = -94.325213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065279925, states[0] = -94.045868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073010941, states[0] = -94.312589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081686577, states[0] = -93.054804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089870087, states[0] = -94.318340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098464330, states[0] = -94.298213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107143712, states[0] = -41.927654, states[40]= 0.000212
Saving checkpoint... 
Iteration: 1114932399, states[0] = -94.282799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122500279, states[0] = -94.309240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131632344, states[0] = -94.324043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140563545, states[0] = -94.319793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147921228, states[0] = -94.275486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156448682, states[0] = -94.293789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164664711, states[0] = -94.323839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172785982, states[0] = -94.298824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180813692, states[0] = -94.137663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189221800, states[0] = -94.300924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197655912, states[0] = -94.323264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206409422, states[0] = -94.266355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214440285, states[0] = -94.312878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222645017, states[0] = -43.472661, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1231503281, states[0] = 14.386917, states[40]= 1.354063
Saving checkpoint... 
Iteration: 1239639359, states[0] = -94.322378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247662627, states[0] = -94.302290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255797603, states[0] = -94.096492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263021912, states[0] = 24.832832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270998890, states[0] = -94.306399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278765821, states[0] = -94.319724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287445908, states[0] = -94.287002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295322224, states[0] = -94.317119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303206058, states[0] = -94.299623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310917498, states[0] = -94.292142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318576457, states[0] = 15.337144, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1327414888, states[0] = -94.291949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335605479, states[0] = -94.319687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345016006, states[0] = -94.307091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353488889, states[0] = -94.302276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361444497, states[0] = -94.310213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369846230, states[0] = -94.195098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378060723, states[0] = -94.304484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386416913, states[0] = -94.268632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394370682, states[0] = -94.313216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403124572, states[0] = -94.319294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411264146, states[0] = -94.295614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420280386, states[0] = -94.294874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429054802, states[0] = -94.303897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437022443, states[0] = 24.938603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445323526, states[0] = -94.314553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453966148, states[0] = -94.292966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462620916, states[0] = -16.529781, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1470811237, states[0] = -94.314668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479097620, states[0] = 3.971200, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1487016923, states[0] = -94.306937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497180684, states[0] = -90.641850, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.162503
 - CaMKt in component CaMK (millimolar): 0.003652
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.230629
 - nass in component intracellular_ions (millimolar): 7.230768
 - ki in component intracellular_ions (millimolar): 144.400591
 - kss in component intracellular_ions (millimolar): 144.400573
 - cansr in component intracellular_ions (millimolar): 2.454704
 - cajsr in component intracellular_ions (millimolar): 2.455353
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003899
 - hf in component INa (dimensionless): 0.866567
 - hs in component INa (dimensionless): 0.866568
 - j in component INa (dimensionless): 0.866575
 - hsp in component INa (dimensionless): 0.701037
 - jp in component INa (dimensionless): 0.866579
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709313
 - hLp in component INaL (dimensionless): 0.513299
 - a in component Ito (dimensionless): 0.000655
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991157
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005220
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024880
 - xs1 in component IKs (dimensionless): 0.068821
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997525
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:03:12 (77771): called boinc_finish(0)

</stderr_txt>
]]>


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