𝕏

Task 55926983

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_177_1
Workunit 26558948
Created 3 Jul 2024, 14:23:06 UTC
Sent 3 Jul 2024, 15:49:38 UTC
Report deadline 6 Jul 2024, 15:49:38 UTC
Received 4 Jul 2024, 21:40:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 3 min 33 sec
CPU time 1 hours 22 min 24 sec
Validate state Valid
Credit 45.64
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.14 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_177.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_177_1_r1363858835_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pieske_333-conf_177_1_r1363858835_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.001069
     * GNaL_b in INaL: 0.005697
     * Gto_b in Ito: 0.086545
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031301
     * GKs_b in IKs: 0.001890
     * GK1_b in IK1: 0.164248
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.239830
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037179
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8445849, states[0] = -87.149232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17117377, states[0] = -87.587471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26325114, states[0] = -87.838643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35506651, states[0] = 22.402373, states[40]= 0.045055
Saving checkpoint... 
Iteration: 44389248, states[0] = -15.168862, states[40]= 0.001995
Saving checkpoint... 
Iteration: 54033489, states[0] = 7.339360, states[40]= 0.007148
Saving checkpoint... 
Iteration: 63275147, states[0] = -87.241053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72176829, states[0] = 19.612776, states[40]= 0.014283
Saving checkpoint... 
Iteration: 80614527, states[0] = -87.666924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88675267, states[0] = 19.569530, states[40]= 0.014146
Saving checkpoint... 
Iteration: 95630992, states[0] = -87.778389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104998719, states[0] = 22.862224, states[40]= 0.055262
Saving checkpoint... 
Iteration: 114052091, states[0] = -19.784393, states[40]= 0.001283
Saving checkpoint... 
Iteration: 121939801, states[0] = -87.563965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129834643, states[0] = 20.794799, states[40]= 0.021275
Saving checkpoint... 
Iteration: 137917701, states[0] = -69.773916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 145980665, states[0] = -87.848110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154532742, states[0] = -0.480355, states[40]= 0.005879
Saving checkpoint... 
Iteration: 162343154, states[0] = 15.447039, states[40]= 0.008778
Saving checkpoint... 
Iteration: 171638231, states[0] = -87.829338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180186292, states[0] = 8.183556, states[40]= 0.007270
Saving checkpoint... 
Iteration: 188330391, states[0] = 20.188307, states[40]= 0.016959
Saving checkpoint... 
Iteration: 196716484, states[0] = -28.194504, states[40]= 0.000614
Saving checkpoint... 
Iteration: 204557369, states[0] = -39.645943, states[40]= 0.000167
Saving checkpoint... 
Iteration: 212464019, states[0] = -87.818568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220644368, states[0] = -87.860176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229877984, states[0] = -25.620747, states[40]= 0.000771
Saving checkpoint... 
Iteration: 238019819, states[0] = 3.608535, states[40]= 0.006633
Saving checkpoint... 
Iteration: 246107714, states[0] = -87.745431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254152418, states[0] = 21.970034, states[40]= 0.037128
Saving checkpoint... 
Iteration: 262712515, states[0] = -31.828668, states[40]= 0.000429
Saving checkpoint... 
Iteration: 271349921, states[0] = 3.523146, states[40]= 0.006619
Saving checkpoint... 
Iteration: 279728886, states[0] = -57.103843, states[40]= 0.000013
Saving checkpoint... 
Iteration: 287951740, states[0] = -87.803026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296153864, states[0] = 19.825286, states[40]= 0.015170
Saving checkpoint... 
Iteration: 304417561, states[0] = -87.241198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312470111, states[0] = 41.667690, states[40]= 0.047618
Saving checkpoint... 
Iteration: 320656924, states[0] = 17.378942, states[40]= 0.010000
Saving checkpoint... 
Iteration: 328543321, states[0] = -37.391756, states[40]= 0.000224
Saving checkpoint... 
Iteration: 337089715, states[0] = -87.681251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345468238, states[0] = 35.006939, states[40]= 0.106811
Saving checkpoint... 
Iteration: 353458951, states[0] = -87.845351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361327618, states[0] = 12.927221, states[40]= 0.008030
Saving checkpoint... 
Iteration: 369356316, states[0] = -14.761650, states[40]= 0.002085
Saving checkpoint... 
Iteration: 377491130, states[0] = 13.844480, states[40]= 0.008248
Saving checkpoint... 
Iteration: 385571926, states[0] = -86.118032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394394053, states[0] = -73.298350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402724699, states[0] = -70.047046, states[40]= 0.000002
Saving checkpoint... 
Iteration: 411092826, states[0] = -87.752495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418904380, states[0] = -86.929166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426758228, states[0] = -87.753786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434946360, states[0] = -87.832390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443228394, states[0] = -82.592710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452068017, states[0] = -86.992190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460373960, states[0] = -51.979504, states[40]= 0.000028
Saving checkpoint... 
Iteration: 468172365, states[0] = -5.077826, states[40]= 0.004702
Saving checkpoint... 
Iteration: 475998473, states[0] = 1.494850, states[40]= 0.006276
Saving checkpoint... 
Iteration: 483715973, states[0] = -68.967260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 491514560, states[0] = -20.111512, states[40]= 0.001245
Saving checkpoint... 
Iteration: 500406035, states[0] = -87.671416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508004899, states[0] = -9.014238, states[40]= 0.003543
Saving checkpoint... 
Iteration: 515609198, states[0] = -87.844521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523962911, states[0] = 20.410904, states[40]= 0.018322
Saving checkpoint... 
Iteration: 532526491, states[0] = -42.288583, states[40]= 0.000116
Saving checkpoint... 
Iteration: 541002225, states[0] = -9.839486, states[40]= 0.003306
Saving checkpoint... 
Iteration: 548742294, states[0] = -87.736246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557704853, states[0] = -62.850676, states[40]= 0.000005
Saving checkpoint... 
Iteration: 564904839, states[0] = -87.721973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572256669, states[0] = -87.802797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580703934, states[0] = -65.057422, states[40]= 0.000004
Saving checkpoint... 
Iteration: 589752593, states[0] = -87.794740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598371614, states[0] = -69.730849, states[40]= 0.000002
Saving checkpoint... 
Iteration: 605978390, states[0] = 7.209728, states[40]= 0.007140
Saving checkpoint... 
Iteration: 613224136, states[0] = -87.570000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621502370, states[0] = -21.251930, states[40]= 0.001124
Saving checkpoint... 
Iteration: 629378689, states[0] = -84.794823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637294216, states[0] = 16.217752, states[40]= 0.009151
Saving checkpoint... 
Iteration: 645995332, states[0] = -14.785346, states[40]= 0.002080
Saving checkpoint... 
Iteration: 653532500, states[0] = -69.275005, states[40]= 0.000002
Saving checkpoint... 
Iteration: 662271375, states[0] = 29.198454, states[40]= 0.122321
Saving checkpoint... 
Iteration: 670941676, states[0] = 23.107118, states[40]= 0.060588
Saving checkpoint... 
Iteration: 678959325, states[0] = 14.797284, states[40]= 0.008531
Saving checkpoint... 
Iteration: 687172643, states[0] = -35.367778, states[40]= 0.000287
Saving checkpoint... 
Iteration: 696093761, states[0] = -87.851535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703675520, states[0] = -41.570502, states[40]= 0.000128
Saving checkpoint... 
Iteration: 712826535, states[0] = -21.204806, states[40]= 0.001128
Saving checkpoint... 
Iteration: 720691253, states[0] = -67.238159, states[40]= 0.000003
Saving checkpoint... 
Iteration: 728802673, states[0] = 4.742273, states[40]= 0.006802
Saving checkpoint... 
Iteration: 736819956, states[0] = -15.307895, states[40]= 0.001975
Saving checkpoint... 
Iteration: 744788038, states[0] = 13.663583, states[40]= 0.008201
Saving checkpoint... 
Iteration: 752680393, states[0] = -55.346259, states[40]= 0.000017
Saving checkpoint... 
Iteration: 761078859, states[0] = -87.827312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769736405, states[0] = -87.800691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777988939, states[0] = -24.369150, states[40]= 0.000858
Saving checkpoint... 
Iteration: 785975247, states[0] = -6.668978, states[40]= 0.004237
Saving checkpoint... 
Iteration: 794268376, states[0] = 20.725137, states[40]= 0.020683
Saving checkpoint... 
Iteration: 802480102, states[0] = -15.372097, states[40]= 0.001963
Saving checkpoint... 
Iteration: 811122752, states[0] = 8.495051, states[40]= 0.007312
Saving checkpoint... 
Iteration: 819175308, states[0] = -57.650857, states[40]= 0.000012
Saving checkpoint... 
Iteration: 827556195, states[0] = -87.772469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836020022, states[0] = -79.211496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844811647, states[0] = -18.821732, states[40]= 0.001404
Saving checkpoint... 
Iteration: 852746552, states[0] = -87.856063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861247564, states[0] = -42.291922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869035436, states[0] = -87.664611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877230689, states[0] = -87.817147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885027315, states[0] = -87.374759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892797323, states[0] = -5.972700, states[40]= 0.004442
Saving checkpoint... 
Iteration: 900582205, states[0] = 26.257936, states[40]= 0.108790
Saving checkpoint... 
Iteration: 908140303, states[0] = -21.158438, states[40]= 0.001133
Saving checkpoint... 
Iteration: 916746606, states[0] = 27.492892, states[40]= 0.117287
Saving checkpoint... 
Iteration: 925300350, states[0] = -14.247408, states[40]= 0.002193
Saving checkpoint... 
Iteration: 933687041, states[0] = -87.093792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942147244, states[0] = -35.503008, states[40]= 0.000283
Saving checkpoint... 
Iteration: 949741955, states[0] = 31.415212, states[40]= 0.120725
Saving checkpoint... 
Iteration: 958074776, states[0] = 30.277325, states[40]= 0.122449
Saving checkpoint... 
Iteration: 966089377, states[0] = 18.771676, states[40]= 0.011976
Saving checkpoint... 
Iteration: 974414590, states[0] = 21.630105, states[40]= 0.031374
Saving checkpoint... 
Iteration: 982753114, states[0] = 19.313918, states[40]= 0.013333
Saving checkpoint... 
Iteration: 991299681, states[0] = -22.604650, states[40]= 0.000998
Saving checkpoint... 
Iteration: 999609710, states[0] = 4.109232, states[40]= 0.006709
Saving checkpoint... 
Iteration: 1007772454, states[0] = 6.533466, states[40]= 0.007050
Saving checkpoint... 
Iteration: 1016055749, states[0] = -87.834126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023445114, states[0] = 0.216017, states[40]= 0.006027
Saving checkpoint... 
Iteration: 1031834204, states[0] = -79.879019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039821044, states[0] = -59.354358, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1047588443, states[0] = 15.178172, states[40]= 0.008670
Saving checkpoint... 
Iteration: 1055280791, states[0] = -5.637161, states[40]= 0.004541
Saving checkpoint... 
Iteration: 1063581736, states[0] = 17.807102, states[40]= 0.010453
Saving checkpoint... 
Iteration: 1071847611, states[0] = -87.648310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080828624, states[0] = -78.822350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089211829, states[0] = -87.824327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097755124, states[0] = 12.216902, states[40]= 0.007887
Saving checkpoint... 
Iteration: 1105831267, states[0] = -84.967286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114481067, states[0] = -60.615605, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1122376162, states[0] = -87.827309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130974431, states[0] = -53.232363, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1139274487, states[0] = -8.225835, states[40]= 0.003775
Saving checkpoint... 
Iteration: 1148078541, states[0] = 15.095155, states[40]= 0.008639
Saving checkpoint... 
Iteration: 1156334984, states[0] = -87.491477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165225767, states[0] = 22.996920, states[40]= 0.058236
Saving checkpoint... 
Iteration: 1173316310, states[0] = -73.576707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181512624, states[0] = -87.736857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190159065, states[0] = -86.494072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199059164, states[0] = 21.488684, states[40]= 0.029267
Saving checkpoint... 
Iteration: 1207962027, states[0] = -46.564361, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1216005995, states[0] = -87.718558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223947823, states[0] = -29.219563, states[40]= 0.000557
Saving checkpoint... 
Iteration: 1232032017, states[0] = -87.827574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240415747, states[0] = 6.614431, states[40]= 0.007061
Saving checkpoint... 
Iteration: 1248362151, states[0] = -87.822758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256599058, states[0] = -12.180434, states[40]= 0.002676
Saving checkpoint... 
Iteration: 1264835448, states[0] = -87.724819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273125248, states[0] = -50.895037, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1281549591, states[0] = 22.000865, states[40]= 0.037697
Saving checkpoint... 
Iteration: 1290346169, states[0] = -87.782973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298624683, states[0] = -53.737356, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1306312712, states[0] = -85.890809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314054613, states[0] = 18.755424, states[40]= 0.011943
Saving checkpoint... 
Iteration: 1322094361, states[0] = -14.750625, states[40]= 0.002087
Saving checkpoint... 
Iteration: 1330110023, states[0] = -37.666371, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1338017547, states[0] = -87.815384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346281240, states[0] = -46.163348, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1354424245, states[0] = -14.452140, states[40]= 0.002149
Saving checkpoint... 
Iteration: 1362492136, states[0] = -87.723407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370980757, states[0] = -87.524957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378827844, states[0] = -87.744399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386151497, states[0] = -87.680276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393761658, states[0] = -25.722972, states[40]= 0.000764
Saving checkpoint... 
Iteration: 1402261272, states[0] = -26.369513, states[40]= 0.000723
Saving checkpoint... 
Iteration: 1411310633, states[0] = -87.553463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419611147, states[0] = -51.673490, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1427281659, states[0] = -58.397536, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1435458585, states[0] = -76.756721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444214189, states[0] = 15.861112, states[40]= 0.008965
Saving checkpoint... 
Iteration: 1452999929, states[0] = -87.794718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461055276, states[0] = 10.190092, states[40]= 0.007550
Saving checkpoint... 
Iteration: 1469113654, states[0] = -62.764908, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1477910773, states[0] = -12.887479, states[40]= 0.002502
Saving checkpoint... 
Iteration: 1486142605, states[0] = -87.692996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495105837, states[0] = -54.898286, states[40]= 0.000018
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.734775
 - CaMKt in component CaMK (millimolar): 0.041699
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 6.963325
 - nass in component intracellular_ions (millimolar): 6.963473
 - ki in component intracellular_ions (millimolar): 144.959448
 - kss in component intracellular_ions (millimolar): 144.959415
 - cansr in component intracellular_ions (millimolar): 1.609520
 - cajsr in component intracellular_ions (millimolar): 1.180894
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007450
 - hf in component INa (dimensionless): 0.693138
 - hs in component INa (dimensionless): 0.692903
 - j in component INa (dimensionless): 0.681972
 - hsp in component INa (dimensionless): 0.448125
 - jp in component INa (dimensionless): 0.654794
 - mL in component INaL (dimensionless): 0.000193
 - hL in component INaL (dimensionless): 0.291626
 - hLp in component INaL (dimensionless): 0.135394
 - a in component Ito (dimensionless): 0.001011
 - iF in component Ito (dimensionless): 0.999542
 - iS in component Ito (dimensionless): 0.174491
 - ap in component Ito (dimensionless): 0.000515
 - iFp in component Ito (dimensionless): 0.999542
 - iSp in component Ito (dimensionless): 0.210956
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.802641
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966399
 - jca in component ICaL (dimensionless): 0.947183
 - ffp in component ICaL (dimensionless): 0.999854
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009360
 - xrf in component IKr (dimensionless): 0.029293
 - xrs in component IKr (dimensionless): 0.788566
 - xs1 in component IKs (dimensionless): 0.461024
 - xs2 in component IKs (dimensionless): 0.001230
 - xk1 in component IK1 (dimensionless): 0.996802
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:20:01 (75744): called boinc_finish(0)

</stderr_txt>
]]>


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