𝕏

Task 55926534

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_176_0
Workunit 26558724
Created 3 Jul 2024, 14:22:55 UTC
Sent 3 Jul 2024, 15:47:17 UTC
Report deadline 7 Jul 2024, 1:23:17 UTC
Received 6 Jul 2024, 5:43:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 32 min 28 sec
CPU time 2 hours 30 min 57 sec
Validate state Valid
Credit 61.36
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_176.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_176_0_r529027469_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_176_0_r529027469_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.781917
     * GNaL_b in INaL: 0.005461
     * Gto_b in Ito: 0.087027
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031343
     * GKs_b in IKs: 0.001917
     * GK1_b in IK1: 0.164857
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.541450
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032298
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18668390, states[0] = -94.701240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36388385, states[0] = -95.049882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52071915, states[0] = 1.358522, states[40]= 0.004419
Saving checkpoint... 
Iteration: 68318336, states[0] = -94.993740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84070505, states[0] = 2.460515, states[40]= 0.004518
Saving checkpoint... 
Iteration: 101067553, states[0] = 3.994208, states[40]= 0.004638
Saving checkpoint... 
Iteration: 117258245, states[0] = -94.929536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134098379, states[0] = -17.972334, states[40]= 0.001129
Saving checkpoint... 
Iteration: 150623965, states[0] = -42.268576, states[40]= 0.000094
Saving checkpoint... 
Iteration: 165525674, states[0] = 19.679182, states[40]= 0.006768
Saving checkpoint... 
Iteration: 182682834, states[0] = -94.790308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199177858, states[0] = -94.753566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214508123, states[0] = 23.608313, states[40]= 0.082594
Saving checkpoint... 
Iteration: 232130557, states[0] = -48.977742, states[40]= 0.000033
Saving checkpoint... 
Iteration: 247693999, states[0] = -94.820141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263895957, states[0] = -95.015169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281207347, states[0] = -94.847259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295629405, states[0] = -47.761273, states[40]= 0.000040
Saving checkpoint... 
Iteration: 313780950, states[0] = -94.950258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330936385, states[0] = -95.025488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346948070, states[0] = -95.027822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363545582, states[0] = 13.175955, states[40]= 0.005011
Saving checkpoint... 
Iteration: 378366477, states[0] = -95.004563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395144372, states[0] = -64.354668, states[40]= 0.000002
Saving checkpoint... 
Iteration: 411080076, states[0] = -2.718369, states[40]= 0.003822
Saving checkpoint... 
Iteration: 427195637, states[0] = -94.823450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444541831, states[0] = 14.555268, states[40]= 0.005114
Saving checkpoint... 
Iteration: 461535285, states[0] = 16.832962, states[40]= 0.005447
Saving checkpoint... 
Iteration: 477585815, states[0] = -6.784928, states[40]= 0.003012
Saving checkpoint... 
Iteration: 495399228, states[0] = -95.015965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512323698, states[0] = -94.982917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529630636, states[0] = -49.052611, states[40]= 0.000033
Saving checkpoint... 
Iteration: 546702232, states[0] = -94.836960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564760844, states[0] = -94.928993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580567703, states[0] = 4.049821, states[40]= 0.004638
Saving checkpoint... 
Iteration: 595344086, states[0] = -94.994243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609993203, states[0] = -95.034640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625292440, states[0] = -94.960280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642727052, states[0] = -94.882147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660734055, states[0] = -94.893173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677005897, states[0] = 26.009093, states[40]= 0.132816
Saving checkpoint... 
Iteration: 692748740, states[0] = -94.913951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710316415, states[0] = -94.978135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724980086, states[0] = -95.032826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741350372, states[0] = -94.997224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758423718, states[0] = -95.022346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773976829, states[0] = -95.032327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789186224, states[0] = -94.801076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805871256, states[0] = -95.006178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822325718, states[0] = -94.983940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836669929, states[0] = -94.367190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852200570, states[0] = -94.833392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868664946, states[0] = -92.936514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884266158, states[0] = -94.934780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901606086, states[0] = -25.082042, states[40]= 0.000708
Saving checkpoint... 
Iteration: 916898916, states[0] = -95.015588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933449007, states[0] = -95.027602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947931885, states[0] = -95.024094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964244803, states[0] = -94.908490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981137650, states[0] = -56.605357, states[40]= 0.000009
Saving checkpoint... 
Iteration: 996705283, states[0] = -94.842721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011765371, states[0] = -94.933825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027633955, states[0] = -52.585791, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1044295248, states[0] = -94.962326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062806793, states[0] = -94.971220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081987981, states[0] = -95.033658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097422290, states[0] = -95.021776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114991568, states[0] = -95.034097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129674837, states[0] = -94.693251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144222935, states[0] = -94.874964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159288137, states[0] = -94.956224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177557142, states[0] = 8.673980, states[40]= 0.004852
Saving checkpoint... 
Iteration: 1196585645, states[0] = -6.653194, states[40]= 0.003040
Saving checkpoint... 
Iteration: 1212039628, states[0] = 15.343526, states[40]= 0.005200
Saving checkpoint... 
Iteration: 1228043571, states[0] = 13.920610, states[40]= 0.005061
Saving checkpoint... 
Iteration: 1242406960, states[0] = -95.017697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258988227, states[0] = -95.033571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274057767, states[0] = 8.417326, states[40]= 0.004844
Saving checkpoint... 
Iteration: 1288761611, states[0] = -94.929392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303578088, states[0] = -1.474293, states[40]= 0.004027
Saving checkpoint... 
Iteration: 1317322007, states[0] = -94.981326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333680661, states[0] = -94.777586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351347408, states[0] = -94.995386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368679903, states[0] = -94.772269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387106261, states[0] = -25.245674, states[40]= 0.000700
Saving checkpoint... 
Iteration: 1402402440, states[0] = -95.016304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422189427, states[0] = -94.808965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437787843, states[0] = -94.955778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453331190, states[0] = -94.986732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470911858, states[0] = -95.018878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486139924, states[0] = -59.141752, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1501044932, states[0] = -92.408213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518433441, states[0] = -78.540648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534555729, states[0] = 4.678811, states[40]= 0.005304
Saving checkpoint... 
Iteration: 1550830083, states[0] = -75.407737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565999076, states[0] = -95.301665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581697657, states[0] = -35.031015, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1599575169, states[0] = -95.290188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615143642, states[0] = -95.260409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632556179, states[0] = -95.274788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647616325, states[0] = 21.668489, states[40]= 0.016270
Saving checkpoint... 
Iteration: 1662474326, states[0] = -95.140774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677573343, states[0] = -95.291382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695559676, states[0] = -95.279105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711645576, states[0] = -94.584725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727321538, states[0] = -95.232974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743992573, states[0] = -29.800486, states[40]= 0.000471
Saving checkpoint... 
Iteration: 1760563055, states[0] = -95.110414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778500404, states[0] = -38.354739, states[40]= 0.000167
Saving checkpoint... 
Iteration: 1794808373, states[0] = -95.211872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809859296, states[0] = -95.048639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825942196, states[0] = -95.057647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842636139, states[0] = -56.489727, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1859128687, states[0] = -47.880840, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1875545291, states[0] = 13.166006, states[40]= 0.005019
Saving checkpoint... 
Iteration: 1891385422, states[0] = -95.015221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908860666, states[0] = -95.003832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925661414, states[0] = -90.188705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942425551, states[0] = -95.022964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959650278, states[0] = -72.334351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1977825207, states[0] = -94.983164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994363004, states[0] = -95.002204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010728992, states[0] = -94.884440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027694694, states[0] = -94.820384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044784013, states[0] = -94.951923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061565131, states[0] = 5.241558, states[40]= 0.004712
Saving checkpoint... 
Iteration: 2078003772, states[0] = 32.350156, states[40]= 0.158135
Saving checkpoint... 
Iteration: 2094522058, states[0] = 20.543614, states[40]= 0.008103
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.910286
 - CaMKt in component CaMK (millimolar): 0.007081
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.571532
 - nass in component intracellular_ions (millimolar): 6.571592
 - ki in component intracellular_ions (millimolar): 145.404317
 - kss in component intracellular_ions (millimolar): 145.404298
 - cansr in component intracellular_ions (millimolar): 1.318344
 - cajsr in component intracellular_ions (millimolar): 1.280223
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003615
 - hf in component INa (dimensionless): 0.880147
 - hs in component INa (dimensionless): 0.880142
 - j in component INa (dimensionless): 0.880113
 - hsp in component INa (dimensionless): 0.726106
 - jp in component INa (dimensionless): 0.880094
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709990
 - hLp in component INaL (dimensionless): 0.451807
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620832
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695758
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935798
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001626
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329229
 - xs1 in component IKs (dimensionless): 0.241235
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:43:09 (54690): called boinc_finish(0)

</stderr_txt>
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