𝕏

Task 55926017

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_274_0
Workunit 26558466
Created 3 Jul 2024, 14:22:35 UTC
Sent 3 Jul 2024, 15:43:58 UTC
Report deadline 7 Jul 2024, 1:19:58 UTC
Received 3 Jul 2024, 19:34:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241770
Run time 2 hours 40 min 30 sec
CPU time 2 hours 16 min 13 sec
Validate state Valid
Credit 63.05
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_274.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_274_0_r1767172692_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_274_0_r1767172692_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.761355
     * GNaL_b in INaL: 0.005976
     * Gto_b in Ito: 0.083290
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.167794
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.328552
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035194
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13894331, states[0] = -95.124030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27428829, states[0] = -95.102428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40756485, states[0] = -94.990418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54125594, states[0] = -44.685655, states[40]= 0.000065
Saving checkpoint... 
Iteration: 67469544, states[0] = -95.075573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80848786, states[0] = -95.037636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94318676, states[0] = -95.018395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107781585, states[0] = -94.988487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121212636, states[0] = -94.897307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134617720, states[0] = -35.533566, states[40]= 0.000243
Saving checkpoint... 
Iteration: 148015110, states[0] = 22.295568, states[40]= 0.018363
Saving checkpoint... 
Iteration: 161416394, states[0] = -95.052345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174878981, states[0] = -95.041072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188370071, states[0] = -95.037640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201892427, states[0] = -95.045134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215493470, states[0] = -95.065131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229034279, states[0] = 17.529202, states[40]= 0.005655
Saving checkpoint... 
Iteration: 242508707, states[0] = 23.942738, states[40]= 0.071444
Saving checkpoint... 
Iteration: 255973347, states[0] = -95.062335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269432050, states[0] = -95.055030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282962849, states[0] = -95.060695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296499361, states[0] = -95.065605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310165941, states[0] = -93.553660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323701984, states[0] = -94.874542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337269317, states[0] = -94.972365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350854338, states[0] = -95.030729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364487728, states[0] = -95.064160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378040786, states[0] = 15.278386, states[40]= 0.005245
Saving checkpoint... 
Iteration: 391594161, states[0] = -13.279295, states[40]= 0.001721
Saving checkpoint... 
Iteration: 405127606, states[0] = -45.274455, states[40]= 0.000059
Saving checkpoint... 
Iteration: 418699452, states[0] = -94.869545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432222839, states[0] = -94.911626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445805274, states[0] = -95.003049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459297397, states[0] = -94.997225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472791857, states[0] = -94.992842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486415158, states[0] = -95.050979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499955092, states[0] = -95.059254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513497428, states[0] = -95.065235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527137643, states[0] = -56.158930, states[40]= 0.000010
Saving checkpoint... 
Iteration: 540726722, states[0] = -94.917764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554189614, states[0] = -94.849165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567808275, states[0] = -95.005072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581339667, states[0] = -95.023658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594884838, states[0] = -95.042215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608385809, states[0] = -95.042525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621909330, states[0] = -95.049408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635467200, states[0] = -95.061133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649016548, states[0] = 22.062679, states[40]= 0.014653
Saving checkpoint... 
Iteration: 662608603, states[0] = -26.766366, states[40]= 0.000627
Saving checkpoint... 
Iteration: 676226274, states[0] = -94.916975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689826654, states[0] = -95.016570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703386816, states[0] = -95.042794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717030997, states[0] = 18.576745, states[40]= 0.006004
Saving checkpoint... 
Iteration: 730643391, states[0] = -62.863014, states[40]= 0.000003
Saving checkpoint... 
Iteration: 744291213, states[0] = -94.992149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757963802, states[0] = -95.060529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771642746, states[0] = -62.079696, states[40]= 0.000004
Saving checkpoint... 
Iteration: 785367207, states[0] = -95.035781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799054424, states[0] = 10.092565, states[40]= 0.004933
Saving checkpoint... 
Iteration: 812646662, states[0] = -67.026852, states[40]= 0.000002
Saving checkpoint... 
Iteration: 826351484, states[0] = -95.029160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840126386, states[0] = -44.008888, states[40]= 0.000072
Saving checkpoint... 
Iteration: 853800833, states[0] = -94.999574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867485538, states[0] = -95.063568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881244459, states[0] = -94.943106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894971265, states[0] = -95.061583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908680404, states[0] = -94.818572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922466474, states[0] = -95.060844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936209348, states[0] = -94.887993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949883715, states[0] = -95.041624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963564953, states[0] = 5.654379, states[40]= 0.004755
Saving checkpoint... 
Iteration: 977269217, states[0] = -94.971860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990880137, states[0] = -95.040387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004721820, states[0] = -94.909604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018395534, states[0] = -95.045305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032001176, states[0] = 49.184394, states[40]= 0.038239
Saving checkpoint... 
Iteration: 1045630218, states[0] = -48.029382, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1059278942, states[0] = -94.981274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072971302, states[0] = -95.061478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086643999, states[0] = -63.610868, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1100390362, states[0] = -95.043676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114079040, states[0] = -1.625359, states[40]= 0.004006
Saving checkpoint... 
Iteration: 1127827937, states[0] = -95.017031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141471619, states[0] = -95.061483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155272418, states[0] = -94.974970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168969306, states[0] = -95.061122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182653302, states[0] = -77.038264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196413181, states[0] = -95.050044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210108146, states[0] = -26.337011, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1223733716, states[0] = -94.927953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237437951, states[0] = -95.055614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251112595, states[0] = -30.526208, states[40]= 0.000446
Saving checkpoint... 
Iteration: 1264720693, states[0] = -94.907581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278356762, states[0] = -95.031205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291969657, states[0] = -95.061099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305627435, states[0] = -45.095585, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1319362768, states[0] = -95.033687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332958846, states[0] = -95.059372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346618672, states[0] = -36.325094, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1360267023, states[0] = -94.969354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373850375, states[0] = -95.028317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387585176, states[0] = -5.762106, states[40]= 0.003228
Saving checkpoint... 
Iteration: 1401357680, states[0] = -95.031522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414932016, states[0] = -95.054279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428524712, states[0] = 20.343933, states[40]= 0.007282
Saving checkpoint... 
Iteration: 1442150857, states[0] = -73.048351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455803347, states[0] = -95.001043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469535104, states[0] = 17.257412, states[40]= 0.005586
Saving checkpoint... 
Iteration: 1483219381, states[0] = -94.905254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496910393, states[0] = -95.049145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510716096, states[0] = -95.206675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524398524, states[0] = -33.629077, states[40]= 0.000307
Saving checkpoint... 
Iteration: 1538062436, states[0] = -95.285828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551754447, states[0] = -95.075019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565551486, states[0] = -95.026616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579317859, states[0] = -58.014194, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1593007899, states[0] = 25.465673, states[40]= 0.082347
Saving checkpoint... 
Iteration: 1606756913, states[0] = -95.299416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620450676, states[0] = -95.022567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634170405, states[0] = -5.840645, states[40]= 0.003628
Saving checkpoint... 
Iteration: 1647873253, states[0] = -95.315567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661673694, states[0] = -95.316131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675260877, states[0] = 1.313802, states[40]= 0.004980
Saving checkpoint... 
Iteration: 1688946857, states[0] = -95.291230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702605970, states[0] = -43.914602, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1716182286, states[0] = -95.189500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729912216, states[0] = -51.379842, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1743517393, states[0] = -95.253687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757233519, states[0] = -83.131427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770846261, states[0] = -95.290668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784473340, states[0] = -8.587370, states[40]= 0.002970
Saving checkpoint... 
Iteration: 1798000131, states[0] = -37.316143, states[40]= 0.000192
Saving checkpoint... 
Iteration: 1811655664, states[0] = -87.586781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825236939, states[0] = -94.963760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838812212, states[0] = -95.028273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852260249, states[0] = -94.976196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865735695, states[0] = -94.940197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879359666, states[0] = -95.038441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892875200, states[0] = -95.042349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906417509, states[0] = -95.053515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919934945, states[0] = -95.056469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933441624, states[0] = -95.057163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946943818, states[0] = -95.057149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960407422, states[0] = -95.048615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973956993, states[0] = -95.059011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987510288, states[0] = 23.296303, states[40]= 0.049481
Saving checkpoint... 
Iteration: 2001111753, states[0] = -29.741978, states[40]= 0.000483
Saving checkpoint... 
Iteration: 2014620807, states[0] = -38.411155, states[40]= 0.000164
Saving checkpoint... 
Iteration: 2028167227, states[0] = -93.965329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041723400, states[0] = -94.911536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055254811, states[0] = -94.955301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068802726, states[0] = -95.000183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082334308, states[0] = -95.019907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095843784, states[0] = -95.024721, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.940378
 - CaMKt in component CaMK (millimolar): 0.006941
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573522
 - nass in component intracellular_ions (millimolar): 6.573581
 - ki in component intracellular_ions (millimolar): 145.404947
 - kss in component intracellular_ions (millimolar): 145.404928
 - cansr in component intracellular_ions (millimolar): 1.308728
 - cajsr in component intracellular_ions (millimolar): 1.270700
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003604
 - hf in component INa (dimensionless): 0.880668
 - hs in component INa (dimensionless): 0.880663
 - j in component INa (dimensionless): 0.880635
 - hsp in component INa (dimensionless): 0.727089
 - jp in component INa (dimensionless): 0.880617
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710809
 - hLp in component INaL (dimensionless): 0.452785
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.620627
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.695377
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934371
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333176
 - xs1 in component IKs (dimensionless): 0.243284
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997327
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:16:01 (1414377): called boinc_finish(0)

</stderr_txt>
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