𝕏

Task 55925901

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_473_1
Workunit 26558408
Created 3 Jul 2024, 14:22:29 UTC
Sent 3 Jul 2024, 15:39:57 UTC
Report deadline 7 Jul 2024, 1:15:57 UTC
Received 6 Jul 2024, 6:52:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241440
Run time 2 hours 40 min 13 sec
CPU time 2 hours 32 min 37 sec
Validate state Valid
Credit 62.12
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.68 MB
Peak swap size 5.26 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_473.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_473_1_r632949178_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_473_1_r632949178_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.341650
     * GNaL_b in INaL: 0.006093
     * Gto_b in Ito: 0.081537
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031513
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.162341
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.440102
     * GKb_b in IKb: 0.003827
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034562
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14059157, states[0] = 6.575467, states[40]= 0.004837
Saving checkpoint... 
Iteration: 28004646, states[0] = 29.835608, states[40]= 0.151562
Saving checkpoint... 
Iteration: 42898688, states[0] = -95.067210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56770537, states[0] = -94.980412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70537684, states[0] = 16.293099, states[40]= 0.005459
Saving checkpoint... 
Iteration: 84488101, states[0] = -95.060938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98656516, states[0] = -82.713814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112624687, states[0] = -42.455545, states[40]= 0.000090
Saving checkpoint... 
Iteration: 127873987, states[0] = -95.027619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142280130, states[0] = -94.969192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156336569, states[0] = -95.009198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170350982, states[0] = -95.016031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184784550, states[0] = -94.971984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199159584, states[0] = -87.036157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214147063, states[0] = -67.260926, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228901304, states[0] = -95.034083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243181087, states[0] = -94.798640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257417853, states[0] = -95.038449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271794276, states[0] = -94.979815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286187229, states[0] = -94.823752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301749990, states[0] = -94.934065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315730478, states[0] = -94.906395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329712439, states[0] = -94.875810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344235220, states[0] = -94.913593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358254552, states[0] = -94.939738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372567537, states[0] = 4.537790, states[40]= 0.004704
Saving checkpoint... 
Iteration: 388141455, states[0] = -60.351124, states[40]= 0.000005
Saving checkpoint... 
Iteration: 402990894, states[0] = -95.051508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417708710, states[0] = -94.868821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432887811, states[0] = -95.029642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447532182, states[0] = 18.339580, states[40]= 0.005933
Saving checkpoint... 
Iteration: 461975517, states[0] = -95.049389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477875599, states[0] = -95.025345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492153320, states[0] = -76.416961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507044025, states[0] = 14.193487, states[40]= 0.005170
Saving checkpoint... 
Iteration: 522023614, states[0] = 20.780394, states[40]= 0.007789
Saving checkpoint... 
Iteration: 536726115, states[0] = -94.899308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551288806, states[0] = -94.975012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566856396, states[0] = -95.017495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581299661, states[0] = -94.983870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595834286, states[0] = -95.006535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610062186, states[0] = 6.946063, states[40]= 0.004841
Saving checkpoint... 
Iteration: 624153631, states[0] = -76.929361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638160058, states[0] = -87.704453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653398758, states[0] = -95.032942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667602009, states[0] = -20.483682, states[40]= 0.000940
Saving checkpoint... 
Iteration: 681022964, states[0] = 20.938273, states[40]= 0.008069
Saving checkpoint... 
Iteration: 695919788, states[0] = -95.038603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710181503, states[0] = -94.800878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724325327, states[0] = -95.001311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739821723, states[0] = -94.999101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754510566, states[0] = 23.495768, states[40]= 0.046555
Saving checkpoint... 
Iteration: 769185183, states[0] = -94.817259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783627926, states[0] = -45.502732, states[40]= 0.000057
Saving checkpoint... 
Iteration: 798239783, states[0] = -94.919951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812706935, states[0] = -94.865213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828500810, states[0] = 45.642498, states[40]= 0.013369
Saving checkpoint... 
Iteration: 843020907, states[0] = 21.409578, states[40]= 0.009255
Saving checkpoint... 
Iteration: 857334003, states[0] = -95.006222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871857369, states[0] = -95.017742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885845010, states[0] = -95.011959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900392568, states[0] = -95.030895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916004318, states[0] = 31.247418, states[40]= 0.149225
Saving checkpoint... 
Iteration: 930336318, states[0] = -95.007439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944859896, states[0] = -95.018796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958748272, states[0] = -94.931427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973053464, states[0] = 10.557265, states[40]= 0.004977
Saving checkpoint... 
Iteration: 987407682, states[0] = -95.035290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002643225, states[0] = -62.439123, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1016934867, states[0] = -95.041855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030785001, states[0] = -94.971373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044529586, states[0] = 19.143584, states[40]= 0.006280
Saving checkpoint... 
Iteration: 1058589973, states[0] = -9.488319, states[40]= 0.002438
Saving checkpoint... 
Iteration: 1072846993, states[0] = -95.012820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087433876, states[0] = -95.041600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102273249, states[0] = -94.960127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116588344, states[0] = -8.136817, states[40]= 0.002725
Saving checkpoint... 
Iteration: 1130758363, states[0] = -94.943845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144980493, states[0] = -95.049685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159270317, states[0] = -94.957082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173667063, states[0] = -93.650800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188802793, states[0] = -94.985890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202945563, states[0] = -95.043909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216917216, states[0] = -95.037652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230966505, states[0] = -95.047557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245315941, states[0] = -94.995098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259567761, states[0] = 4.432896, states[40]= 0.004697
Saving checkpoint... 
Iteration: 1275154705, states[0] = -78.735888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289065855, states[0] = 5.315568, states[40]= 0.004754
Saving checkpoint... 
Iteration: 1303298264, states[0] = -94.982346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317172147, states[0] = -94.554826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331227452, states[0] = -94.900984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345332462, states[0] = -95.005071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360574150, states[0] = 1.237662, states[40]= 0.004408
Saving checkpoint... 
Iteration: 1375037945, states[0] = 16.402423, states[40]= 0.005444
Saving checkpoint... 
Iteration: 1389008188, states[0] = 24.575437, states[40]= 0.080284
Saving checkpoint... 
Iteration: 1403391777, states[0] = -95.030341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417567999, states[0] = 4.320769, states[40]= 0.004689
Saving checkpoint... 
Iteration: 1431561667, states[0] = 7.170582, states[40]= 0.004851
Saving checkpoint... 
Iteration: 1446607535, states[0] = -25.665577, states[40]= 0.000680
Saving checkpoint... 
Iteration: 1460925196, states[0] = -95.039434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474734907, states[0] = -94.912436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488852590, states[0] = -95.015218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502612484, states[0] = -95.183469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516559520, states[0] = 3.274396, states[40]= 0.005162
Saving checkpoint... 
Iteration: 1530443390, states[0] = -93.028854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545363128, states[0] = 0.357590, states[40]= 0.004843
Saving checkpoint... 
Iteration: 1559307787, states[0] = -95.222308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573213446, states[0] = 23.207610, states[40]= 0.026801
Saving checkpoint... 
Iteration: 1587226538, states[0] = -95.258183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601273687, states[0] = -95.160232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615357739, states[0] = -95.107682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630473081, states[0] = -95.312352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644739441, states[0] = -91.276545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658126429, states[0] = 18.881447, states[40]= 0.007990
Saving checkpoint... 
Iteration: 1672104405, states[0] = -95.227468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685988408, states[0] = -95.325061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699527077, states[0] = 18.623774, states[40]= 0.007820
Saving checkpoint... 
Iteration: 1714828930, states[0] = 17.875958, states[40]= 0.007413
Saving checkpoint... 
Iteration: 1729120992, states[0] = -95.254666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742967878, states[0] = -95.308876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756914670, states[0] = -54.199276, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1770907154, states[0] = 26.505817, states[40]= 0.094446
Saving checkpoint... 
Iteration: 1784492558, states[0] = -28.912285, states[40]= 0.000513
Saving checkpoint... 
Iteration: 1799672134, states[0] = -95.312534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813501468, states[0] = 48.562394, states[40]= 0.063226
Saving checkpoint... 
Iteration: 1827556145, states[0] = 8.885405, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1841346707, states[0] = -95.033079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855538830, states[0] = 15.896950, states[40]= 0.005392
Saving checkpoint... 
Iteration: 1869223692, states[0] = -94.903824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883313668, states[0] = -94.999203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898423095, states[0] = -95.042473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912156874, states[0] = -82.836412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925677081, states[0] = -94.756343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939362966, states[0] = -95.020600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953215061, states[0] = -94.880301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967161502, states[0] = -89.678427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982134114, states[0] = -52.143381, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1995790141, states[0] = -94.975454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009876416, states[0] = -95.024816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023500814, states[0] = 45.731508, states[40]= 0.013632
Saving checkpoint... 
Iteration: 2037778390, states[0] = -94.964640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051728385, states[0] = -94.902028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066530081, states[0] = 18.994033, states[40]= 0.006205
Saving checkpoint... 
Iteration: 2080525436, states[0] = 20.315775, states[40]= 0.007165
Saving checkpoint... 
Iteration: 2094781563, states[0] = -94.967550, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.927417
 - CaMKt in component CaMK (millimolar): 0.006904
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.532784
 - nass in component intracellular_ions (millimolar): 6.532844
 - ki in component intracellular_ions (millimolar): 145.446279
 - kss in component intracellular_ions (millimolar): 145.446259
 - cansr in component intracellular_ions (millimolar): 1.306779
 - cajsr in component intracellular_ions (millimolar): 1.268782
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880444
 - hs in component INa (dimensionless): 0.880439
 - j in component INa (dimensionless): 0.880410
 - hsp in component INa (dimensionless): 0.726666
 - jp in component INa (dimensionless): 0.880391
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710336
 - hLp in component INaL (dimensionless): 0.451993
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620254
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694818
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933931
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001585
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335763
 - xs1 in component IKs (dimensionless): 0.243738
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:52:26 (24156): called boinc_finish(0)

</stderr_txt>
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