𝕏

Task 55925505

Name HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468_1
Workunit 26558210
Created 3 Jul 2024, 14:22:19 UTC
Sent 3 Jul 2024, 15:40:00 UTC
Report deadline 7 Jul 2024, 1:16:00 UTC
Received 5 Jul 2024, 23:15:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238434
Run time 1 hours 25 min 1 sec
CPU time 54 min 20 sec
Validate state Valid
Credit 60.68
Device peak FLOPS 6.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.18 MB
Peak swap size 5.30 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468_1_r852060119_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468_1_r852060119_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.782806
     * GNaL_b in INaL: 0.005603
     * Gto_b in Ito: 0.086685
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.163518
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.549843
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036402
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17487877, states[0] = -95.118655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33163028, states[0] = -93.926366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48538609, states[0] = 15.222457, states[40]= 0.005297
Saving checkpoint... 
Iteration: 64614747, states[0] = -35.054196, states[40]= 0.000253
Saving checkpoint... 
Iteration: 80494661, states[0] = -95.057181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94880151, states[0] = -95.029105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111890012, states[0] = -95.029843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128039289, states[0] = 15.310822, states[40]= 0.005263
Saving checkpoint... 
Iteration: 143454829, states[0] = -95.042999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159814664, states[0] = -94.991646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176409805, states[0] = -95.032255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192276838, states[0] = -94.960721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208748304, states[0] = -94.928581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225386915, states[0] = -95.025000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242209363, states[0] = -94.867058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258152977, states[0] = -78.634383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276281140, states[0] = -94.964388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292023668, states[0] = 20.122982, states[40]= 0.007556
Saving checkpoint... 
Iteration: 309669594, states[0] = -94.478417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326037314, states[0] = 16.038787, states[40]= 0.005373
Saving checkpoint... 
Iteration: 342816228, states[0] = -94.991598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359491001, states[0] = -95.046680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374237170, states[0] = -94.913001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391976650, states[0] = -95.044749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410241705, states[0] = -94.919395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427750812, states[0] = -94.931413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443617115, states[0] = -36.362104, states[40]= 0.000213
Saving checkpoint... 
Iteration: 460627754, states[0] = -47.133363, states[40]= 0.000043
Saving checkpoint... 
Iteration: 476861083, states[0] = -95.015079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492386686, states[0] = -95.024617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508193667, states[0] = -94.835595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523383625, states[0] = -95.023573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539508865, states[0] = 23.277455, states[40]= 0.069495
Saving checkpoint... 
Iteration: 555054721, states[0] = 9.480766, states[40]= 0.004887
Saving checkpoint... 
Iteration: 571518879, states[0] = 21.143942, states[40]= 0.010849
Saving checkpoint... 
Iteration: 587075899, states[0] = -0.477965, states[40]= 0.004169
Saving checkpoint... 
Iteration: 603573441, states[0] = 0.901045, states[40]= 0.004345
Saving checkpoint... 
Iteration: 619819154, states[0] = -94.993289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635630831, states[0] = -50.416985, states[40]= 0.000026
Saving checkpoint... 
Iteration: 651140336, states[0] = -61.000743, states[40]= 0.000004
Saving checkpoint... 
Iteration: 666666815, states[0] = -94.054554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682482568, states[0] = -95.045383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697278319, states[0] = -94.961446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713082414, states[0] = -4.661252, states[40]= 0.003450
Saving checkpoint... 
Iteration: 728639406, states[0] = -59.921327, states[40]= 0.000005
Saving checkpoint... 
Iteration: 746647333, states[0] = -69.851124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763281300, states[0] = -94.964194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780357498, states[0] = -95.013355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797676149, states[0] = -94.759472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814388980, states[0] = -95.025161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830752588, states[0] = -94.933374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846031770, states[0] = 17.870500, states[40]= 0.005842
Saving checkpoint... 
Iteration: 862252715, states[0] = -94.933511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878542734, states[0] = 14.097365, states[40]= 0.005121
Saving checkpoint... 
Iteration: 894776975, states[0] = -94.960034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910310905, states[0] = -94.987686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925132077, states[0] = -51.763874, states[40]= 0.000020
Saving checkpoint... 
Iteration: 941434470, states[0] = -95.037038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957406649, states[0] = -95.030324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973849958, states[0] = -95.009835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989662052, states[0] = -91.863256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006471116, states[0] = -95.043551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021638723, states[0] = -59.137199, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1038299371, states[0] = -94.979241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055669518, states[0] = -94.470212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071127002, states[0] = -46.340763, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1087750178, states[0] = -94.930190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104638552, states[0] = -58.941927, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1120570545, states[0] = 2.420651, states[40]= 0.004504
Saving checkpoint... 
Iteration: 1136384870, states[0] = -95.023605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152187973, states[0] = -94.822488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168028054, states[0] = 18.977229, states[40]= 0.006380
Saving checkpoint... 
Iteration: 1183718418, states[0] = -94.882697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199964387, states[0] = -95.042387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215891058, states[0] = -95.025571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231921748, states[0] = -95.034003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247930019, states[0] = -95.035885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263272037, states[0] = -94.954919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278505812, states[0] = 26.317145, states[40]= 0.132620
Saving checkpoint... 
Iteration: 1294000098, states[0] = -82.994131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310452699, states[0] = -95.040344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327707177, states[0] = -94.862150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342332587, states[0] = -95.000766, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468_1_r852060119_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703162050454916_ORdGradInc_k_26-Pueyo_APDR-conf_468_1_r852060119_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.782806
     * GNaL_b in INaL: 0.005603
     * Gto_b in Ito: 0.086685
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.163518
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.549843
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036402
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1342332587
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.000766 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1349837087, states[0] = -95.003194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361045659, states[0] = 13.007601, states[40]= 0.005037
Saving checkpoint... 
Iteration: 1377260847, states[0] = -94.942828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393343801, states[0] = -95.006606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409485445, states[0] = -95.045305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425046836, states[0] = 12.562706, states[40]= 0.005010
Saving checkpoint... 
Iteration: 1441002208, states[0] = 43.131614, states[40]= 0.098086
Saving checkpoint... 
Iteration: 1458093261, states[0] = -13.681600, states[40]= 0.001656
Saving checkpoint... 
Iteration: 1474245469, states[0] = -94.923824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490852420, states[0] = -95.010644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502545634, states[0] = -93.764605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518763365, states[0] = -95.091375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529766722, states[0] = -2.701920, states[40]= 0.004283
Saving checkpoint... 
Iteration: 1545337866, states[0] = 13.608538, states[40]= 0.006197
Saving checkpoint... 
Iteration: 1561291890, states[0] = -29.234846, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1571870985, states[0] = -95.144369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587321592, states[0] = 20.090532, states[40]= 0.009846
Saving checkpoint... 
Iteration: 1603242050, states[0] = 11.363678, states[40]= 0.005921
Saving checkpoint... 
Iteration: 1619027592, states[0] = -95.257420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635372631, states[0] = -8.925703, states[40]= 0.002886
Saving checkpoint... 
Iteration: 1647115952, states[0] = -57.787648, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1662340315, states[0] = 12.183308, states[40]= 0.006025
Saving checkpoint... 
Iteration: 1677567082, states[0] = -95.302370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693688689, states[0] = -95.192501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704859187, states[0] = -95.295219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716156779, states[0] = -95.105376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732075094, states[0] = -95.162027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747184432, states[0] = -95.316488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762993579, states[0] = -95.202548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779905909, states[0] = 27.392774, states[40]= 0.118135
Saving checkpoint... 
Iteration: 1796216681, states[0] = -58.758920, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1812653410, states[0] = -85.618595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829845620, states[0] = -95.036529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845691163, states[0] = -94.848045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862465580, states[0] = -95.053304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878784358, states[0] = -94.973202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894830283, states[0] = -95.003396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910889342, states[0] = -95.027210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921919988, states[0] = -95.035027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938453368, states[0] = -95.041201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948976902, states[0] = -95.044618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964221101, states[0] = -94.887312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975432310, states[0] = -95.036270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991522381, states[0] = 20.419950, states[40]= 0.008126
Saving checkpoint... 
Iteration: 2002291897, states[0] = -94.972799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018153529, states[0] = -79.588073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033496690, states[0] = -95.046324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048968132, states[0] = -95.042428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060602035, states[0] = -21.962519, states[40]= 0.000845
Saving checkpoint... 
Iteration: 2072406669, states[0] = -95.029592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088968581, states[0] = -95.042440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099404614, states[0] = -95.028995, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.922478
 - CaMKt in component CaMK (millimolar): 0.006939
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.567631
 - nass in component intracellular_ions (millimolar): 6.567690
 - ki in component intracellular_ions (millimolar): 145.410616
 - kss in component intracellular_ions (millimolar): 145.410596
 - cansr in component intracellular_ions (millimolar): 1.308997
 - cajsr in component intracellular_ions (millimolar): 1.271108
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880358
 - hs in component INa (dimensionless): 0.880354
 - j in component INa (dimensionless): 0.880325
 - hsp in component INa (dimensionless): 0.726505
 - jp in component INa (dimensionless): 0.880306
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710609
 - hLp in component INaL (dimensionless): 0.453048
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622083
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697223
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001589
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329517
 - xs1 in component IKs (dimensionless): 0.239836
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
23:15:17 (14496): called boinc_finish(0)

</stderr_txt>
]]>


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