𝕏

Task 55922052

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0
Workunit 26556656
Created 3 Jul 2024, 12:39:46 UTC
Sent 3 Jul 2024, 15:11:37 UTC
Report deadline 6 Jul 2024, 15:11:41 UTC
Received 4 Jul 2024, 10:39:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233156
Run time 30 min 5 sec
CPU time 21 min 12 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.77 MB
Peak swap size 391.85 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 46310130, states[0] = -84.648915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100493556, states[0] = -81.386381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152728907, states[0] = 16.042179, states[40]= 0.000033
Saving checkpoint... 
Iteration: 204744456, states[0] = 8.767198, states[40]= 0.000101
Saving checkpoint... 
Iteration: 258687367, states[0] = 29.840355, states[40]= 0.137997
Saving checkpoint... 
Iteration: 309044784, states[0] = 27.940364, states[40]= 0.000068
Saving checkpoint... 
Iteration: 361983449, states[0] = -84.631204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420820399, states[0] = -55.939037, states[40]= 0.000013
Saving checkpoint... 
Iteration: 477300751, states[0] = -84.574059, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517796500, states[0] = -24.378761, states[40]= 0.000179
Saving checkpoint... 
Iteration: 565009776, states[0] = -84.658605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 621382789, states[0] = 31.154883, states[40]= 0.003138
Saving checkpoint... 
Iteration: 676569383, states[0] = -84.213275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736019540, states[0] = -84.656783, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 736019540
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.656783 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 788127296, states[0] = -6.284286, states[40]= 0.000305
Saving checkpoint... 
Iteration: 844543505, states[0] = -83.813101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897483226, states[0] = -25.575096, states[40]= 0.000181
Saving checkpoint... 
Iteration: 951956340, states[0] = -84.437778, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 951956340
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.437778 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 998047615, states[0] = -84.674962, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 998047615
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.674962 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1035636641, states[0] = -84.475506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089301637, states[0] = -84.456612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144131485, states[0] = 4.559133, states[40]= 0.000168


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1144131485
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 4.559133 (After loading)
 - states[40]: 0.000168 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1187752085, states[0] = 29.160048, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1239775258, states[0] = 20.152109, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1293200112, states[0] = -59.075659, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1351411402, states[0] = 30.753489, states[40]= 0.052120
Saving checkpoint... 
Iteration: 1399392974, states[0] = -84.653503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1457083697, states[0] = 30.850728, states[40]= 0.046083


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1457083697
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 30.850728 (After loading)
 - states[40]: 0.046083 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Schmidt_666-conf_583_0_r1856547248_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.232646
     * GNaL_b in INaL: 0.005581
     * Gto_b in Ito: 0.088435
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031872
     * GKs_b in IKs: 0.001977
     * GK1_b in IK1: 0.161999
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.590129
     * GKb_b in IKb: 0.003776
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037067
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1457083697
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 30.850728 (After loading)
 - states[40]: 0.046083 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.542692
 - CaMKt in component CaMK (millimolar): 0.039122
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.853590
 - nass in component intracellular_ions (millimolar): 6.853745
 - ki in component intracellular_ions (millimolar): 144.807641
 - kss in component intracellular_ions (millimolar): 144.807613
 - cansr in component intracellular_ions (millimolar): 2.057397
 - cajsr in component intracellular_ions (millimolar): 1.811449
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010266
 - hf in component INa (dimensionless): 0.572071
 - hs in component INa (dimensionless): 0.571917
 - j in component INa (dimensionless): 0.571082
 - hsp in component INa (dimensionless): 0.325091
 - jp in component INa (dimensionless): 0.570393
 - mL in component INaL (dimensionless): 0.000355
 - hL in component INaL (dimensionless): 0.346015
 - hLp in component INaL (dimensionless): 0.150871
 - a in component Ito (dimensionless): 0.001253
 - iF in component Ito (dimensionless): 0.999200
 - iS in component Ito (dimensionless): 0.366426
 - ap in component Ito (dimensionless): 0.000639
 - iFp in component Ito (dimensionless): 0.999200
 - iSp in component Ito (dimensionless): 0.400959
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.844059
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995832
 - jca in component ICaL (dimensionless): 0.998142
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005910
 - xrf in component IKr (dimensionless): 0.000401
 - xrs in component IKr (dimensionless): 0.672432
 - xs1 in component IKs (dimensionless): 0.384352
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996791
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
10:13:16 (72414): called boinc_finish(0)

</stderr_txt>
]]>