𝕏

Task 55919762

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pieske_500-conf_877_0
Workunit 26555513
Created 3 Jul 2024, 12:38:32 UTC
Sent 3 Jul 2024, 14:59:15 UTC
Report deadline 6 Jul 2024, 14:59:15 UTC
Received 4 Jul 2024, 10:46:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231066
Run time 1 hours 15 min 12 sec
CPU time 1 hours 3 min 22 sec
Validate state Valid
Credit 45.07
Device peak FLOPS 4.29 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 5.23 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pieske_500-conf_877.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pieske_500-conf_877_0_r1687621424_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pieske_500-conf_877_0_r1687621424_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.846434
     * GNaL_b in INaL: 0.005929
     * Gto_b in Ito: 0.088000
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032262
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.159366
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.552189
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031719
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8166963, states[0] = -87.337177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20542313, states[0] = 9.757184, states[40]= 0.005900
Saving checkpoint... 
Iteration: 32709621, states[0] = -87.364191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45035773, states[0] = 13.638640, states[40]= 0.006255
Saving checkpoint... 
Iteration: 57406515, states[0] = -87.221055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69554763, states[0] = 2.212061, states[40]= 0.005260
Saving checkpoint... 
Iteration: 81695129, states[0] = -87.316319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94010764, states[0] = 23.031017, states[40]= 0.039262
Saving checkpoint... 
Iteration: 106341334, states[0] = -37.826462, states[40]= 0.000175
Saving checkpoint... 
Iteration: 118618355, states[0] = -73.912139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130853903, states[0] = -53.361799, states[40]= 0.000017
Saving checkpoint... 
Iteration: 142955795, states[0] = -87.333827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155205830, states[0] = -87.333700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167351662, states[0] = -50.479994, states[40]= 0.000027
Saving checkpoint... 
Iteration: 178416111, states[0] = -87.240393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189648265, states[0] = -87.179650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201596678, states[0] = -44.254225, states[40]= 0.000070
Saving checkpoint... 
Iteration: 213699239, states[0] = -87.320514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225749227, states[0] = -87.397437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237830927, states[0] = -25.201952, states[40]= 0.000691
Saving checkpoint... 
Iteration: 249977239, states[0] = -87.368856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262144450, states[0] = -87.154211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274346811, states[0] = -44.415041, states[40]= 0.000069
Saving checkpoint... 
Iteration: 286276737, states[0] = 18.111698, states[40]= 0.007243
Saving checkpoint... 
Iteration: 298606881, states[0] = -57.198356, states[40]= 0.000009
Saving checkpoint... 
Iteration: 310684749, states[0] = -87.288651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323005592, states[0] = 26.091804, states[40]= 0.119209
Saving checkpoint... 
Iteration: 335169643, states[0] = -87.249967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347452305, states[0] = -87.326403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358846493, states[0] = -44.023352, states[40]= 0.000073
Saving checkpoint... 
Iteration: 370549555, states[0] = 5.836726, states[40]= 0.005602
Saving checkpoint... 
Iteration: 382323361, states[0] = -15.950361, states[40]= 0.001573
Saving checkpoint... 
Iteration: 394326405, states[0] = -19.675268, states[40]= 0.001105
Saving checkpoint... 
Iteration: 406099578, states[0] = -47.848082, states[40]= 0.000041
Saving checkpoint... 
Iteration: 417760352, states[0] = 23.148606, states[40]= 0.043004
Saving checkpoint... 
Iteration: 429929084, states[0] = -87.274714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437893547, states[0] = -87.145284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450210285, states[0] = -87.341169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462249291, states[0] = -87.397223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474656522, states[0] = -87.211000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486816600, states[0] = -8.074868, states[40]= 0.003227
Saving checkpoint... 
Iteration: 499052403, states[0] = 3.962650, states[40]= 0.005441
Saving checkpoint... 
Iteration: 511499738, states[0] = -87.397679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524066517, states[0] = -7.985388, states[40]= 0.003249
Saving checkpoint... 
Iteration: 536053726, states[0] = 3.052913, states[40]= 0.005350
Saving checkpoint... 
Iteration: 544066198, states[0] = -7.643840, states[40]= 0.003333
Saving checkpoint... 
Iteration: 556579101, states[0] = -22.974849, states[40]= 0.000831
Saving checkpoint... 
Iteration: 569043077, states[0] = 9.772936, states[40]= 0.005888
Saving checkpoint... 
Iteration: 581446231, states[0] = -87.313893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589782931, states[0] = 15.236771, states[40]= 0.006466
Saving checkpoint... 
Iteration: 602294537, states[0] = 8.919352, states[40]= 0.005826
Saving checkpoint... 
Iteration: 614759876, states[0] = 23.279373, states[40]= 0.047836
Saving checkpoint... 
Iteration: 627191261, states[0] = -87.303180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638833117, states[0] = -27.858668, states[40]= 0.000548
Saving checkpoint... 
Iteration: 651190512, states[0] = -87.301496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663529201, states[0] = 17.019010, states[40]= 0.006856
Saving checkpoint... 
Iteration: 675921297, states[0] = -87.254118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688072516, states[0] = -14.923408, states[40]= 0.001740
Saving checkpoint... 
Iteration: 700526620, states[0] = 18.161946, states[40]= 0.007265
Saving checkpoint... 
Iteration: 712755046, states[0] = 26.979850, states[40]= 0.129292
Saving checkpoint... 
Iteration: 724042605, states[0] = 10.045209, states[40]= 0.005908
Saving checkpoint... 
Iteration: 736016783, states[0] = 21.630765, states[40]= 0.013564
Saving checkpoint... 
Iteration: 744294613, states[0] = 8.874502, states[40]= 0.005823
Saving checkpoint... 
Iteration: 756166401, states[0] = -87.240430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768361232, states[0] = -63.116595, states[40]= 0.000004
Saving checkpoint... 
Iteration: 780462391, states[0] = -87.344518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792756225, states[0] = 25.309242, states[40]= 0.106445
Saving checkpoint... 
Iteration: 805080334, states[0] = -24.478410, states[40]= 0.000734
Saving checkpoint... 
Iteration: 817041142, states[0] = 10.877579, states[40]= 0.005973
Saving checkpoint... 
Iteration: 829064930, states[0] = -6.321909, states[40]= 0.003658
Saving checkpoint... 
Iteration: 841458160, states[0] = -87.336914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853695352, states[0] = -87.311754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866147538, states[0] = -87.174953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877875883, states[0] = -83.613317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890197813, states[0] = -87.316831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901117598, states[0] = -72.650790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913395136, states[0] = -87.159189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925399819, states[0] = -87.186019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937539510, states[0] = 11.786262, states[40]= 0.006050
Saving checkpoint... 
Iteration: 949849348, states[0] = -47.559682, states[40]= 0.000043
Saving checkpoint... 
Iteration: 962369867, states[0] = -76.181155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974511599, states[0] = 22.847846, states[40]= 0.032817
Saving checkpoint... 
Iteration: 986885636, states[0] = -86.896007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999008043, states[0] = 23.967702, states[40]= 0.072444
Saving checkpoint... 
Iteration: 1011546950, states[0] = 7.468012, states[40]= 0.005723
Saving checkpoint... 
Iteration: 1023843895, states[0] = -40.848838, states[40]= 0.000115
Saving checkpoint... 
Iteration: 1036089718, states[0] = -35.809342, states[40]= 0.000229
Saving checkpoint... 
Iteration: 1048635919, states[0] = -86.916251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057301387, states[0] = 4.643876, states[40]= 0.005503
Saving checkpoint... 
Iteration: 1069522539, states[0] = 19.789860, states[40]= 0.008429
Saving checkpoint... 
Iteration: 1080864939, states[0] = -68.537900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093154713, states[0] = -87.204339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105324083, states[0] = -16.830258, states[40]= 0.001444
Saving checkpoint... 
Iteration: 1117697344, states[0] = -87.315620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129959818, states[0] = -87.339599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142406807, states[0] = -87.211191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153464557, states[0] = -87.347835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164603965, states[0] = -53.403104, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1176716805, states[0] = -87.351576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188974777, states[0] = -87.364162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201411090, states[0] = -87.224417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213826232, states[0] = -19.462019, states[40]= 0.001127
Saving checkpoint... 
Iteration: 1226138467, states[0] = -87.043434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238392810, states[0] = -87.136004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250814065, states[0] = -5.453890, states[40]= 0.003867
Saving checkpoint... 
Iteration: 1261806453, states[0] = 1.080515, states[40]= 0.005114
Saving checkpoint... 
Iteration: 1274143164, states[0] = -87.140152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286629519, states[0] = -85.737753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299125978, states[0] = -83.690070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311590347, states[0] = -36.565041, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1323922848, states[0] = -87.257588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336235475, states[0] = -87.379203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348618901, states[0] = -74.687938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361095534, states[0] = -42.845555, states[40]= 0.000087
Saving checkpoint... 
Iteration: 1373443577, states[0] = -87.307412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385751305, states[0] = 41.623496, states[40]= 0.053641
Saving checkpoint... 
Iteration: 1398114516, states[0] = -67.897911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1410648070, states[0] = -87.177194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422948816, states[0] = -87.318298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435195017, states[0] = -87.310416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446057178, states[0] = 0.530172, states[40]= 0.005037
Saving checkpoint... 
Iteration: 1457953365, states[0] = -87.327254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468902551, states[0] = -87.196311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479808104, states[0] = -0.191234, states[40]= 0.004928
Saving checkpoint... 
Iteration: 1491091183, states[0] = -37.570649, states[40]= 0.000182
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.272662
 - CaMKt in component CaMK (millimolar): 0.019730
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.756609
 - nass in component intracellular_ions (millimolar): 6.756709
 - ki in component intracellular_ions (millimolar): 145.198777
 - kss in component intracellular_ions (millimolar): 145.198750
 - cansr in component intracellular_ions (millimolar): 1.432653
 - cajsr in component intracellular_ions (millimolar): 1.213387
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.007805
 - hf in component INa (dimensionless): 0.676752
 - hs in component INa (dimensionless): 0.676647
 - j in component INa (dimensionless): 0.675928
 - hsp in component INa (dimensionless): 0.430110
 - jp in component INa (dimensionless): 0.673966
 - mL in component INaL (dimensionless): 0.000211
 - hL in component INaL (dimensionless): 0.385948
 - hLp in component INaL (dimensionless): 0.180594
 - a in component Ito (dimensionless): 0.001043
 - iF in component Ito (dimensionless): 0.999504
 - iS in component Ito (dimensionless): 0.293316
 - ap in component Ito (dimensionless): 0.000531
 - iFp in component Ito (dimensionless): 0.999504
 - iSp in component Ito (dimensionless): 0.341080
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.858869
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991200
 - jca in component ICaL (dimensionless): 0.991440
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004243
 - xrf in component IKr (dimensionless): 0.001737
 - xrs in component IKr (dimensionless): 0.670288
 - xs1 in component IKs (dimensionless): 0.382397
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.996917
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:45:49 (17940): called boinc_finish(0)

</stderr_txt>
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