𝕏

Task 55919583

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Drouin_EPI_2000-conf_377_1
Workunit 26555423
Created 3 Jul 2024, 12:38:27 UTC
Sent 3 Jul 2024, 14:57:23 UTC
Report deadline 6 Jul 2024, 14:57:23 UTC
Received 4 Jul 2024, 10:43:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228562
Run time 3 hours 9 min 55 sec
CPU time 1 hours 6 min 36 sec
Validate state Valid
Credit 51.10
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.76 MB
Peak swap size 6.29 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Drouin_EPI_2000-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Drouin_EPI_2000-conf_377_1_r303989749_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Drouin_EPI_2000-conf_377_1_r303989749_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 1, states[0] = -86.877479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 12460177, states[0] = -94.394445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23423311, states[0] = -94.344191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34973899, states[0] = -94.360640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47362414, states[0] = -94.287658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59140393, states[0] = -40.536470, states[40]= 0.000306
Saving checkpoint... 
Iteration: 71073704, states[0] = 15.666504, states[40]= 0.000010
Saving checkpoint... 
Iteration: 88857278, states[0] = -94.391619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103075223, states[0] = 14.660137, states[40]= 0.000014
Saving checkpoint... 
Iteration: 115546196, states[0] = -94.404165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126078224, states[0] = 13.118629, states[40]= 0.000022
Saving checkpoint... 
Iteration: 138479634, states[0] = -94.394405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149064212, states[0] = 19.145554, states[40]= 0.000003
Saving checkpoint... 
Iteration: 158081097, states[0] = 11.606868, states[40]= 0.000032
Saving checkpoint... 
Iteration: 170603222, states[0] = -94.411662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180713144, states[0] = -94.410253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195298244, states[0] = -94.205558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210097082, states[0] = 2.051738, states[40]= 0.000191
Saving checkpoint... 
Iteration: 223530440, states[0] = -94.405657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233493718, states[0] = -94.398641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240172215, states[0] = -86.319194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252101162, states[0] = -0.985877, states[40]= 0.000268
Saving checkpoint... 
Iteration: 270701202, states[0] = -94.409077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282875919, states[0] = -94.399326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293564112, states[0] = -94.407505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301234049, states[0] = -93.947923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310029326, states[0] = 25.330253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318113611, states[0] = -12.935335, states[40]= 0.000350
Saving checkpoint... 
Iteration: 332714704, states[0] = -94.406849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347196482, states[0] = -93.676416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361563686, states[0] = -94.405564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371864320, states[0] = -94.397549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384032715, states[0] = 25.438472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394443600, states[0] = -94.377503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403590166, states[0] = -94.405937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416446935, states[0] = -94.378348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427823515, states[0] = -94.398438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443454666, states[0] = -94.380775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460800708, states[0] = -94.398843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474050427, states[0] = 23.324375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492933553, states[0] = -94.389856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509921086, states[0] = -94.390141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515853950, states[0] = -94.394104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529573674, states[0] = -94.401505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539087153, states[0] = 8.288743, states[40]= 0.000067
Saving checkpoint... 
Iteration: 546451174, states[0] = -94.376443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555929220, states[0] = -94.388338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567469648, states[0] = -94.382632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574193502, states[0] = -93.639142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592313561, states[0] = -94.230945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610476711, states[0] = -94.383611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620794127, states[0] = -94.394682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630944908, states[0] = -94.385242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640022481, states[0] = 24.552150, states[40]= -0.000000
Saving checkpoint... 
Iteration: 656039005, states[0] = 25.180573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667305166, states[0] = -94.209840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678485274, states[0] = -94.384092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690767159, states[0] = -94.394186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702412314, states[0] = -94.351591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711811430, states[0] = -94.391091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723323600, states[0] = -94.247447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737830502, states[0] = -94.389237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750966424, states[0] = -94.380538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762647866, states[0] = -94.396526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774480378, states[0] = -94.380034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785465046, states[0] = -94.374907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796577493, states[0] = -94.394176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804472260, states[0] = -94.376753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814137197, states[0] = -39.411314, states[40]= 0.000368
Saving checkpoint... 
Iteration: 823964862, states[0] = -94.378561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835262125, states[0] = -94.069542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845842284, states[0] = -94.385460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858563349, states[0] = -94.391467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871070914, states[0] = 16.405897, states[40]= 0.000008
Saving checkpoint... 
Iteration: 880899634, states[0] = -94.380945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892081262, states[0] = 11.487060, states[40]= 0.000033
Saving checkpoint... 
Iteration: 902558031, states[0] = -94.389772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913015829, states[0] = 23.004480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921085352, states[0] = 9.304702, states[40]= 0.000054
Saving checkpoint... 
Iteration: 929360811, states[0] = -94.298428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934932131, states[0] = -94.377409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940589813, states[0] = -94.390702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944503111, states[0] = -94.380775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951676873, states[0] = -94.390613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959256271, states[0] = -94.041179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966637686, states[0] = -94.390804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973671282, states[0] = -94.390135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977895818, states[0] = -94.378428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983385068, states[0] = -94.322445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988426886, states[0] = -94.352275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995464275, states[0] = -94.368675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003699772, states[0] = -94.388415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011778747, states[0] = -94.384459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017914246, states[0] = -94.376149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024394360, states[0] = -94.329277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034804873, states[0] = -94.382331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041332712, states[0] = -94.254728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047211090, states[0] = -93.774471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053316462, states[0] = -94.223865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059608168, states[0] = -94.387905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065263089, states[0] = -94.066797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070357553, states[0] = -94.290373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076667421, states[0] = -94.387297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082807545, states[0] = -94.380812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089212944, states[0] = -93.786913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094331133, states[0] = -94.250514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101481125, states[0] = -94.370973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106772434, states[0] = -94.382126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113212732, states[0] = -93.784657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117347497, states[0] = -94.275580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123335205, states[0] = -94.256572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130201929, states[0] = -93.700546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136397505, states[0] = -94.328620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144181409, states[0] = -93.006891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150712147, states[0] = -94.383785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156681771, states[0] = -94.384680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163627147, states[0] = -94.385225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169002774, states[0] = 17.076919, states[40]= 1.747277
Saving checkpoint... 
Iteration: 1174239360, states[0] = -93.952257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179305581, states[0] = -94.196167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184757056, states[0] = -94.380730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189900458, states[0] = -94.372136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194839518, states[0] = -94.375738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199728947, states[0] = -94.381671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205066967, states[0] = 18.050583, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1212122749, states[0] = -23.070051, states[40]= 0.000418
Saving checkpoint... 
Iteration: 1217802673, states[0] = -94.377281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224134188, states[0] = -35.885634, states[40]= 0.000463
Saving checkpoint... 
Iteration: 1230836706, states[0] = -94.374889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236881605, states[0] = -94.371967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241859889, states[0] = -94.373161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248359980, states[0] = -94.288328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254555227, states[0] = -94.379550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260880928, states[0] = -94.371325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266434027, states[0] = -94.348171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272942092, states[0] = -94.367219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280718989, states[0] = -94.379818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288913678, states[0] = -94.368509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295022551, states[0] = 24.568633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298489499, states[0] = -94.367612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301321599, states[0] = -94.227086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303425724, states[0] = -94.342685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306487519, states[0] = -94.366878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308418252, states[0] = -94.338158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311321508, states[0] = -94.226623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315417169, states[0] = -94.337290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319083449, states[0] = 10.344390, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1325056850, states[0] = 21.609030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330132085, states[0] = -33.470129, states[40]= 0.000515
Saving checkpoint... 
Iteration: 1334776352, states[0] = -94.375448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338772755, states[0] = -94.375530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342548005, states[0] = -94.376350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346269442, states[0] = -94.083296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350067494, states[0] = 17.841057, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1354706034, states[0] = -94.378239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360541106, states[0] = -94.375072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369139573, states[0] = -42.205880, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1376306363, states[0] = -94.192355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385380979, states[0] = -94.307200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391959111, states[0] = -94.362798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398629085, states[0] = -94.378565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405335045, states[0] = -94.248244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410839016, states[0] = -94.369637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415853045, states[0] = -94.368640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421152889, states[0] = -58.172865, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1426570587, states[0] = -94.375884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434531302, states[0] = -94.371725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441549884, states[0] = -94.373737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447573443, states[0] = -94.375488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454598660, states[0] = -94.376475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460771682, states[0] = -94.372135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464707444, states[0] = -94.375078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470966734, states[0] = -94.360104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476737924, states[0] = -94.373415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482287072, states[0] = -94.138214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489056337, states[0] = 21.764511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496752812, states[0] = -94.372109, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.233216
 - CaMKt in component CaMK (millimolar): 0.007270
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.430980
 - nass in component intracellular_ions (millimolar): 7.431126
 - ki in component intracellular_ions (millimolar): 144.081034
 - kss in component intracellular_ions (millimolar): 144.081011
 - cansr in component intracellular_ions (millimolar): 2.599816
 - cajsr in component intracellular_ions (millimolar): 2.600736
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003871
 - hf in component INa (dimensionless): 0.867905
 - hs in component INa (dimensionless): 0.867908
 - j in component INa (dimensionless): 0.867922
 - hsp in component INa (dimensionless): 0.703475
 - jp in component INa (dimensionless): 0.867929
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.711169
 - hLp in component INaL (dimensionless): 0.503125
 - a in component Ito (dimensionless): 0.000652
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.999853
 - ap in component Ito (dimensionless): 0.000332
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.999853
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.974644
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005409
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.092194
 - xs1 in component IKs (dimensionless): 0.128110
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997507
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:44:13 (5816): called boinc_finish(0)

</stderr_txt>
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