𝕏

Task 55917719

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_466_1
Workunit 26554492
Created 3 Jul 2024, 12:37:28 UTC
Sent 3 Jul 2024, 14:45:41 UTC
Report deadline 7 Jul 2024, 0:21:41 UTC
Received 4 Jul 2024, 21:04:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240525
Run time 1 hours 55 min 13 sec
CPU time 1 hours 20 min 11 sec
Validate state Valid
Credit 67.94
Device peak FLOPS 7.75 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_466.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_466_1_r405964535_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_466_1_r405964535_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.455407
     * GNaL_b in INaL: 0.005851
     * Gto_b in Ito: 0.082560
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031596
     * GKs_b in IKs: 0.001946
     * GK1_b in IK1: 0.168003
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.035832
     * GKb_b in IKb: 0.003812
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029918
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11404554, states[0] = -95.147724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22353281, states[0] = -95.098749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32493187, states[0] = -95.115741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43479698, states[0] = -95.101355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53786258, states[0] = -95.017445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64157927, states[0] = -88.166120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74347157, states[0] = -95.046879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85344603, states[0] = -95.042354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96385623, states[0] = -95.056606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105385294, states[0] = -95.055070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116376207, states[0] = -95.050613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126196308, states[0] = -94.871325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135648192, states[0] = -70.137117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147016656, states[0] = 22.085534, states[40]= 0.014344
Saving checkpoint... 
Iteration: 156713967, states[0] = -94.903584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167407259, states[0] = -95.057742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178462258, states[0] = -95.069236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190544567, states[0] = 13.860036, states[40]= 0.005122
Saving checkpoint... 
Iteration: 200179095, states[0] = -94.818238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210790882, states[0] = -94.999424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221199013, states[0] = -94.874318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231086763, states[0] = -7.241023, states[40]= 0.002924
Saving checkpoint... 
Iteration: 241537878, states[0] = 16.302549, states[40]= 0.005399
Saving checkpoint... 
Iteration: 251111311, states[0] = -29.764680, states[40]= 0.000483
Saving checkpoint... 
Iteration: 262478564, states[0] = -95.071157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273963856, states[0] = -95.068926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284446433, states[0] = -95.065869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293883324, states[0] = -95.049649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304761274, states[0] = -94.970460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314100000, states[0] = -19.086786, states[40]= 0.001037
Saving checkpoint... 
Iteration: 325711686, states[0] = -94.898320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334331376, states[0] = -95.026833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345110695, states[0] = -29.176716, states[40]= 0.000511
Saving checkpoint... 
Iteration: 356291813, states[0] = -94.999894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367352932, states[0] = -95.037641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379332261, states[0] = -95.027291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389228100, states[0] = -94.926078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399910009, states[0] = -95.057585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410853925, states[0] = -95.038059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421341749, states[0] = -95.032266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432545716, states[0] = 13.433218, states[40]= 0.005092
Saving checkpoint... 
Iteration: 442270486, states[0] = -94.980237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453225661, states[0] = -94.922166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464481960, states[0] = -95.071453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475800513, states[0] = -95.006674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486235560, states[0] = -94.937303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497279550, states[0] = -94.989053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507451641, states[0] = -95.066666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518752136, states[0] = -94.959550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529642164, states[0] = -62.053046, states[40]= 0.000004
Saving checkpoint... 
Iteration: 540235232, states[0] = -94.936790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550032076, states[0] = 18.250148, states[40]= 0.005873
Saving checkpoint... 
Iteration: 560151691, states[0] = -75.299290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570497960, states[0] = -95.073403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579648800, states[0] = -70.803744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591072990, states[0] = 1.646177, states[40]= 0.004455
Saving checkpoint... 
Iteration: 602002849, states[0] = 38.446640, states[40]= 0.129057
Saving checkpoint... 
Iteration: 611448063, states[0] = -95.065945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621431288, states[0] = -95.062559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631393439, states[0] = -95.052695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640617161, states[0] = -35.352125, states[40]= 0.000250
Saving checkpoint... 
Iteration: 651385944, states[0] = -95.050284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661784867, states[0] = -94.993774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671699147, states[0] = -94.874142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682114624, states[0] = -32.914742, states[40]= 0.000341
Saving checkpoint... 
Iteration: 691904331, states[0] = -95.055856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702875935, states[0] = -95.046776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714039299, states[0] = 15.800526, states[40]= 0.005322
Saving checkpoint... 
Iteration: 724218903, states[0] = -94.910794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735487277, states[0] = -95.071987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745408946, states[0] = -95.057084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755956100, states[0] = -95.067297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767096229, states[0] = -15.541497, states[40]= 0.001397
Saving checkpoint... 
Iteration: 777579826, states[0] = -2.299886, states[40]= 0.003910
Saving checkpoint... 
Iteration: 787823963, states[0] = -95.022263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797768183, states[0] = -94.977630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808681783, states[0] = -94.831907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818718521, states[0] = -94.910080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829189364, states[0] = -94.853562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839231701, states[0] = -94.931344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850131773, states[0] = -50.286641, states[40]= 0.000027
Saving checkpoint... 
Iteration: 863672360, states[0] = -94.683967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876512917, states[0] = 22.751131, states[40]= 0.027629
Saving checkpoint... 
Iteration: 890210000, states[0] = -94.894866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902327633, states[0] = -95.024348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913209277, states[0] = -94.893514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924155465, states[0] = -81.880849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935495876, states[0] = -95.072928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947287221, states[0] = -94.995649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959830050, states[0] = -95.025690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969765286, states[0] = -94.974443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981039093, states[0] = 15.874098, states[40]= 0.005332
Saving checkpoint... 
Iteration: 991094589, states[0] = -14.018548, states[40]= 0.001610
Saving checkpoint... 
Iteration: 1002705839, states[0] = -94.886994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014108397, states[0] = -27.002267, states[40]= 0.000617
Saving checkpoint... 
Iteration: 1024643850, states[0] = -64.125068, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1036381811, states[0] = -95.048646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047273163, states[0] = -94.982555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057983956, states[0] = -95.071349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069859127, states[0] = -95.039918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082240152, states[0] = -94.943472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093187552, states[0] = -94.849183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104349189, states[0] = -95.035452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115383316, states[0] = -95.049111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125918886, states[0] = -95.059384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136608900, states[0] = -27.477410, states[40]= 0.000594
Saving checkpoint... 
Iteration: 1150385915, states[0] = -95.049961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161048774, states[0] = 12.264801, states[40]= 0.005028
Saving checkpoint... 
Iteration: 1173725892, states[0] = -94.922080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184091386, states[0] = -11.119870, states[40]= 0.002114
Saving checkpoint... 
Iteration: 1194746818, states[0] = -94.952382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205823107, states[0] = -95.021485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217999165, states[0] = -95.073136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229843029, states[0] = -95.032398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241479714, states[0] = -95.070657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252483519, states[0] = -95.071168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263565261, states[0] = 5.421777, states[40]= 0.004758
Saving checkpoint... 
Iteration: 1273471607, states[0] = -95.069468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284491054, states[0] = -95.072121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294667691, states[0] = -94.206601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307564231, states[0] = 5.887874, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1317496078, states[0] = -95.072712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329165797, states[0] = -93.715913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341355892, states[0] = -95.038347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350732916, states[0] = -94.932850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362521588, states[0] = 21.120589, states[40]= 0.008638
Saving checkpoint... 
Iteration: 1373410645, states[0] = -95.057140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384284555, states[0] = -94.993043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394357226, states[0] = -95.038896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404572307, states[0] = 2.003994, states[40]= 0.004492
Saving checkpoint... 
Iteration: 1417580422, states[0] = -2.682034, states[40]= 0.003843
Saving checkpoint... 
Iteration: 1431153040, states[0] = -77.574184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445935292, states[0] = -95.062896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460582880, states[0] = -4.338108, states[40]= 0.003532
Saving checkpoint... 
Iteration: 1471463645, states[0] = -95.068107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483717138, states[0] = -94.907272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497859516, states[0] = -95.039815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510987469, states[0] = -95.162056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524358944, states[0] = 3.248385, states[40]= 0.005183
Saving checkpoint... 
Iteration: 1535827107, states[0] = -69.915756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1548882327, states[0] = -95.315266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562841795, states[0] = -93.441133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577414921, states[0] = 22.606963, states[40]= 0.020539
Saving checkpoint... 
Iteration: 1591819534, states[0] = 21.228105, states[40]= 0.011611
Saving checkpoint... 
Iteration: 1607708238, states[0] = 25.254579, states[40]= 0.076912
Saving checkpoint... 
Iteration: 1620053174, states[0] = 5.916372, states[40]= 0.005469
Saving checkpoint... 
Iteration: 1633245987, states[0] = 9.782374, states[40]= 0.005789
Saving checkpoint... 
Iteration: 1647217143, states[0] = -95.258828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660382639, states[0] = -95.195195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673282015, states[0] = -95.193940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685107038, states[0] = 26.370627, states[40]= 0.097424
Saving checkpoint... 
Iteration: 1698910624, states[0] = 23.929358, states[40]= 0.046369
Saving checkpoint... 
Iteration: 1711415414, states[0] = -95.256661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723776996, states[0] = -95.325934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736783835, states[0] = -19.895980, states[40]= 0.001060
Saving checkpoint... 
Iteration: 1749646331, states[0] = 9.587773, states[40]= 0.005773
Saving checkpoint... 
Iteration: 1762220632, states[0] = 20.839331, states[40]= 0.010596
Saving checkpoint... 
Iteration: 1775421283, states[0] = 20.624301, states[40]= 0.010110
Saving checkpoint... 
Iteration: 1788155518, states[0] = -95.113261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800066367, states[0] = -0.227756, states[40]= 0.004735
Saving checkpoint... 
Iteration: 1812236145, states[0] = -94.979841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826511780, states[0] = 22.765188, states[40]= 0.034948
Saving checkpoint... 
Iteration: 1839656898, states[0] = -87.193815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853450193, states[0] = -95.079272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867451243, states[0] = -95.074772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880549410, states[0] = 11.909244, states[40]= 0.005019
Saving checkpoint... 
Iteration: 1895535915, states[0] = 16.927715, states[40]= 0.005527
Saving checkpoint... 
Iteration: 1908824909, states[0] = -95.024757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921829773, states[0] = -95.026708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935014292, states[0] = 22.495427, states[40]= 0.021119
Saving checkpoint... 
Iteration: 1947107122, states[0] = -25.852661, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1960225742, states[0] = -94.921892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973553360, states[0] = 10.458472, states[40]= 0.004960
Saving checkpoint... 
Iteration: 1986753124, states[0] = -94.960056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998749789, states[0] = -94.955823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010870982, states[0] = -95.044187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023354747, states[0] = -95.037448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035013978, states[0] = 22.559416, states[40]= 0.022403
Saving checkpoint... 
Iteration: 2047062361, states[0] = 6.716007, states[40]= 0.004824
Saving checkpoint... 
Iteration: 2059438841, states[0] = -95.063219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072131961, states[0] = -50.491382, states[40]= 0.000026
Saving checkpoint... 
Iteration: 2085704557, states[0] = -94.883813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099265427, states[0] = -94.973836, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.948508
 - CaMKt in component CaMK (millimolar): 0.006975
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.550896
 - nass in component intracellular_ions (millimolar): 6.550956
 - ki in component intracellular_ions (millimolar): 145.426776
 - kss in component intracellular_ions (millimolar): 145.426756
 - cansr in component intracellular_ions (millimolar): 1.311907
 - cajsr in component intracellular_ions (millimolar): 1.273892
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003601
 - hf in component INa (dimensionless): 0.880808
 - hs in component INa (dimensionless): 0.880803
 - j in component INa (dimensionless): 0.880775
 - hsp in component INa (dimensionless): 0.727354
 - jp in component INa (dimensionless): 0.880756
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711141
 - hLp in component INaL (dimensionless): 0.453393
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621237
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.696099
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934570
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332430
 - xs1 in component IKs (dimensionless): 0.242538
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997325
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:03:37 (345016): called boinc_finish(0)

</stderr_txt>
]]>


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