𝕏

Task 55917197

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459_0
Workunit 26554232
Created 3 Jul 2024, 12:37:13 UTC
Sent 3 Jul 2024, 14:45:49 UTC
Report deadline 7 Jul 2024, 0:21:49 UTC
Received 3 Jul 2024, 23:18:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224657
Run time 2 hours 6 min 34 sec
CPU time 1 hours 59 min 33 sec
Validate state Valid
Credit 61.70
Device peak FLOPS 3.96 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.09 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459_0_r1247154829_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459_0_r1247154829_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.398379
     * GNaL_b in INaL: 0.005623
     * Gto_b in Ito: 0.082044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031446
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.167254
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.874276
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028881
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459_0_r1247154829_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_459_0_r1247154829_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.398379
     * GNaL_b in INaL: 0.005623
     * Gto_b in Ito: 0.082044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031446
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.167254
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.874276
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028881
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15875645, states[0] = -95.101262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31716190, states[0] = -94.931673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47428015, states[0] = -95.069697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63449637, states[0] = -95.064577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79347914, states[0] = -95.027698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95199624, states[0] = -94.863840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111103089, states[0] = -22.980348, states[40]= 0.000807
Saving checkpoint... 
Iteration: 127034625, states[0] = 17.206274, states[40]= 0.005680
Saving checkpoint... 
Iteration: 142943096, states[0] = -95.049553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158719685, states[0] = -94.895834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174473182, states[0] = -95.053787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190442666, states[0] = -95.048339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206544246, states[0] = 13.763774, states[40]= 0.005171
Saving checkpoint... 
Iteration: 222697966, states[0] = -94.854492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238732513, states[0] = -94.915485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254754848, states[0] = -94.945581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270785500, states[0] = -94.977194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286667749, states[0] = -94.295112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302635883, states[0] = -55.658571, states[40]= 0.000011
Saving checkpoint... 
Iteration: 318696710, states[0] = -94.851743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334687381, states[0] = -94.831591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350525167, states[0] = 20.120866, states[40]= 0.007200
Saving checkpoint... 
Iteration: 366411127, states[0] = -95.040670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382276285, states[0] = -94.968592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398009970, states[0] = 23.508394, states[40]= 0.053534
Saving checkpoint... 
Iteration: 413802532, states[0] = -94.990838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429797134, states[0] = -94.986715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445734740, states[0] = -94.918580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461528014, states[0] = 19.328301, states[40]= 0.006524
Saving checkpoint... 
Iteration: 477275384, states[0] = -94.967657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493169115, states[0] = -94.472245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509012607, states[0] = 22.790826, states[40]= 0.029744
Saving checkpoint... 
Iteration: 524751516, states[0] = -94.941278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540725919, states[0] = -94.904946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556718859, states[0] = -94.893220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572602621, states[0] = -22.307748, states[40]= 0.000840
Saving checkpoint... 
Iteration: 588621556, states[0] = -40.477035, states[40]= 0.000122
Saving checkpoint... 
Iteration: 604721838, states[0] = -94.898227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620641870, states[0] = -62.566834, states[40]= 0.000003
Saving checkpoint... 
Iteration: 636546591, states[0] = 12.873270, states[40]= 0.005108
Saving checkpoint... 
Iteration: 652627343, states[0] = -46.410785, states[40]= 0.000050
Saving checkpoint... 
Iteration: 668645691, states[0] = -67.406093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684742360, states[0] = -94.929240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700707881, states[0] = -94.873390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716706237, states[0] = -94.870269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732752141, states[0] = -94.941922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748636074, states[0] = -55.870100, states[40]= 0.000011
Saving checkpoint... 
Iteration: 764424959, states[0] = -95.043832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779303538, states[0] = -94.991350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794176853, states[0] = -94.783279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808868620, states[0] = -95.026677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822690998, states[0] = -94.839452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836160498, states[0] = -90.563523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851147255, states[0] = -69.550742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867193991, states[0] = -94.845780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883208291, states[0] = -94.874045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899055370, states[0] = 9.392350, states[40]= 0.004959
Saving checkpoint... 
Iteration: 914870135, states[0] = -95.027199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930543604, states[0] = 14.010130, states[40]= 0.005190
Saving checkpoint... 
Iteration: 946371373, states[0] = -95.027654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962282933, states[0] = -94.974436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978029299, states[0] = 18.947619, states[40]= 0.006302
Saving checkpoint... 
Iteration: 993732568, states[0] = -94.914999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009732860, states[0] = -94.915428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025692023, states[0] = -94.841528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041663275, states[0] = -92.822033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057480483, states[0] = -95.053693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073488238, states[0] = -95.054716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089210953, states[0] = -94.878853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102232843, states[0] = -94.915344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113189573, states[0] = -94.836137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126788458, states[0] = -94.979184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141262363, states[0] = -94.953664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155033564, states[0] = 17.594335, states[40]= 0.005777
Saving checkpoint... 
Iteration: 1169618746, states[0] = -37.697241, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1184338908, states[0] = -95.013017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198970922, states[0] = -95.052223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213387929, states[0] = -95.033329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227649004, states[0] = -72.098302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240136308, states[0] = -56.131201, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1252888688, states[0] = -95.033551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266304664, states[0] = -94.991865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279481947, states[0] = -95.053755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292947048, states[0] = -95.048124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306570008, states[0] = 2.816880, states[40]= 0.004595
Saving checkpoint... 
Iteration: 1320073037, states[0] = 1.240662, states[40]= 0.004436
Saving checkpoint... 
Iteration: 1332580452, states[0] = -3.182644, states[40]= 0.003774
Saving checkpoint... 
Iteration: 1346892409, states[0] = -95.034677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360363290, states[0] = -95.024194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373984856, states[0] = -95.054086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387386830, states[0] = -95.032860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400063742, states[0] = 5.798521, states[40]= 0.004807
Saving checkpoint... 
Iteration: 1413471565, states[0] = -95.052185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427127049, states[0] = -46.101592, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1440906043, states[0] = -95.038625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454540975, states[0] = 14.989780, states[40]= 0.005289
Saving checkpoint... 
Iteration: 1467447069, states[0] = -95.048019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481002344, states[0] = 42.528356, states[40]= 0.105943
Saving checkpoint... 
Iteration: 1494777083, states[0] = -94.968659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508405021, states[0] = 30.464928, states[40]= 0.115643
Saving checkpoint... 
Iteration: 1521946632, states[0] = 9.847964, states[40]= 0.005779
Saving checkpoint... 
Iteration: 1534389229, states[0] = -95.169752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547755096, states[0] = 4.874341, states[40]= 0.005391
Saving checkpoint... 
Iteration: 1561274865, states[0] = -10.348819, states[40]= 0.002572
Saving checkpoint... 
Iteration: 1574298448, states[0] = -95.205031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587685009, states[0] = -21.540109, states[40]= 0.000931
Saving checkpoint... 
Iteration: 1601294492, states[0] = -95.201397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614790517, states[0] = -95.194462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627462279, states[0] = -95.296302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640319978, states[0] = -95.246861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653873152, states[0] = -95.306469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667477556, states[0] = -13.633148, states[40]= 0.001898
Saving checkpoint... 
Iteration: 1680877080, states[0] = -95.309911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694067556, states[0] = -95.302058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707777084, states[0] = -95.166783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720675859, states[0] = -95.163922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733873329, states[0] = -95.157868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747107331, states[0] = -95.227509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760155948, states[0] = 4.026797, states[40]= 0.005327
Saving checkpoint... 
Iteration: 1773634320, states[0] = 15.291330, states[40]= 0.006630
Saving checkpoint... 
Iteration: 1787332938, states[0] = -95.265344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801063047, states[0] = 4.401147, states[40]= 0.004890
Saving checkpoint... 
Iteration: 1814782922, states[0] = -95.014803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828070045, states[0] = 1.983334, states[40]= 0.004551
Saving checkpoint... 
Iteration: 1841571695, states[0] = 1.384585, states[40]= 0.004473
Saving checkpoint... 
Iteration: 1855239584, states[0] = -94.938051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870235820, states[0] = -94.927874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885733863, states[0] = -94.921819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901482956, states[0] = -95.056827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916731567, states[0] = -94.915069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928337993, states[0] = -95.013568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941436018, states[0] = -95.046526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954921198, states[0] = -95.042857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968429982, states[0] = -95.044639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981939906, states[0] = -95.046569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995480196, states[0] = -95.053229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009042232, states[0] = 14.522094, states[40]= 0.005238
Saving checkpoint... 
Iteration: 2021300365, states[0] = -94.988252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034059310, states[0] = 7.742538, states[40]= 0.004898
Saving checkpoint... 
Iteration: 2047430278, states[0] = -95.044223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2061059835, states[0] = 7.518455, states[40]= 0.004889
Saving checkpoint... 
Iteration: 2074704669, states[0] = -94.866374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087448522, states[0] = -95.047864, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.931334
 - CaMKt in component CaMK (millimolar): 0.006976
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583621
 - nass in component intracellular_ions (millimolar): 6.583681
 - ki in component intracellular_ions (millimolar): 145.393591
 - kss in component intracellular_ions (millimolar): 145.393571
 - cansr in component intracellular_ions (millimolar): 1.314214
 - cajsr in component intracellular_ions (millimolar): 1.276313
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880511
 - hs in component INa (dimensionless): 0.880507
 - j in component INa (dimensionless): 0.880478
 - hsp in component INa (dimensionless): 0.726793
 - jp in component INa (dimensionless): 0.880459
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710843
 - hLp in component INaL (dimensionless): 0.453338
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621935
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696937
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935365
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333057
 - xs1 in component IKs (dimensionless): 0.240718
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:09:12 (5588): called boinc_finish(0)

</stderr_txt>
]]>


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