𝕏

Task 55917193

Name HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_159_0
Workunit 26554230
Created 3 Jul 2024, 12:37:12 UTC
Sent 3 Jul 2024, 14:45:49 UTC
Report deadline 7 Jul 2024, 0:21:49 UTC
Received 4 Jul 2024, 2:14:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224657
Run time 2 hours 20 min 57 sec
CPU time 2 hours 4 min 39 sec
Validate state Valid
Credit 64.73
Device peak FLOPS 3.96 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.14 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_159.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_159_0_r877782669_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143532529620_ORdGradInc_k_26-Pueyo_APDR-conf_159_0_r877782669_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.898342
     * GNaL_b in INaL: 0.005482
     * Gto_b in Ito: 0.083584
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031975
     * GKs_b in IKs: 0.001897
     * GK1_b in IK1: 0.165306
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.106442
     * GKb_b in IKb: 0.003837
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029588
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13729674, states[0] = -94.957029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27270431, states[0] = -94.973483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40014280, states[0] = 21.892162, states[40]= 0.020743
Saving checkpoint... 
Iteration: 53288547, states[0] = -94.962758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66985063, states[0] = -95.031221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79943770, states[0] = -95.020123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93505382, states[0] = 27.411222, states[40]= 0.142346
Saving checkpoint... 
Iteration: 107124954, states[0] = -45.261740, states[40]= 0.000058
Saving checkpoint... 
Iteration: 120732160, states[0] = -94.878868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134260455, states[0] = -94.915605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146315953, states[0] = -94.963763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159957609, states[0] = -95.014223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173537411, states[0] = 15.983344, states[40]= 0.005394
Saving checkpoint... 
Iteration: 187114977, states[0] = -35.026137, states[40]= 0.000258
Saving checkpoint... 
Iteration: 200532098, states[0] = 17.791170, states[40]= 0.005822
Saving checkpoint... 
Iteration: 214173943, states[0] = -94.705964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227413518, states[0] = -95.004039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240635757, states[0] = -56.613754, states[40]= 0.000009
Saving checkpoint... 
Iteration: 254043269, states[0] = 13.843700, states[40]= 0.005137
Saving checkpoint... 
Iteration: 267264973, states[0] = -94.918733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280579389, states[0] = -3.005696, states[40]= 0.003797
Saving checkpoint... 
Iteration: 294266721, states[0] = -94.920595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308110409, states[0] = -30.608175, states[40]= 0.000436
Saving checkpoint... 
Iteration: 321972725, states[0] = -95.015675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335420988, states[0] = -95.005724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348865871, states[0] = -94.988274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362747187, states[0] = -94.897225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376931490, states[0] = -95.008115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392637607, states[0] = -58.690700, states[40]= 0.000006
Saving checkpoint... 
Iteration: 408476736, states[0] = -95.016200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424333499, states[0] = -94.972845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437116589, states[0] = -36.567728, states[40]= 0.000210
Saving checkpoint... 
Iteration: 449321442, states[0] = -94.965755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462894774, states[0] = -94.998452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476499011, states[0] = -95.019044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490114068, states[0] = -34.122125, states[40]= 0.000289
Saving checkpoint... 
Iteration: 503651098, states[0] = -76.739883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517297189, states[0] = -94.948665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529950972, states[0] = -95.011926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542694387, states[0] = -94.806995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555880058, states[0] = -94.993517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569672715, states[0] = -94.674862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583395577, states[0] = -94.998620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596694479, states[0] = -94.807153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610006242, states[0] = 25.885087, states[40]= 0.122680
Saving checkpoint... 
Iteration: 623609180, states[0] = -29.432475, states[40]= 0.000492
Saving checkpoint... 
Iteration: 638076879, states[0] = -1.407073, states[40]= 0.004066
Saving checkpoint... 
Iteration: 653821090, states[0] = -94.965402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669830565, states[0] = -94.971039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685622514, states[0] = -42.461586, states[40]= 0.000090
Saving checkpoint... 
Iteration: 699733664, states[0] = -94.877926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713105262, states[0] = -25.698909, states[40]= 0.000670
Saving checkpoint... 
Iteration: 724607728, states[0] = -28.047001, states[40]= 0.000558
Saving checkpoint... 
Iteration: 736456843, states[0] = -95.012838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749992611, states[0] = -95.018097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763159532, states[0] = -90.231744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773739245, states[0] = -94.886065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785202465, states[0] = -94.823332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798593495, states[0] = -14.527079, states[40]= 0.001540
Saving checkpoint... 
Iteration: 812088169, states[0] = -9.709440, states[40]= 0.002407
Saving checkpoint... 
Iteration: 824848656, states[0] = -94.980377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838022648, states[0] = 20.473466, states[40]= 0.007958
Saving checkpoint... 
Iteration: 850528277, states[0] = 18.973003, states[40]= 0.006343
Saving checkpoint... 
Iteration: 863753901, states[0] = -94.905437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877135086, states[0] = -55.859817, states[40]= 0.000010
Saving checkpoint... 
Iteration: 887974983, states[0] = -95.015632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898934366, states[0] = -95.008396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911581713, states[0] = -4.603449, states[40]= 0.003490
Saving checkpoint... 
Iteration: 924334969, states[0] = -94.973325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937023188, states[0] = 20.343262, states[40]= 0.007720
Saving checkpoint... 
Iteration: 949893461, states[0] = -94.997725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962417490, states[0] = -95.004449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974492228, states[0] = -95.017903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983967877, states[0] = -95.014495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994802689, states[0] = -94.952586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006832344, states[0] = -94.971822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017926630, states[0] = -95.006604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030267048, states[0] = -94.920447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042679831, states[0] = -94.766882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054625370, states[0] = -45.402572, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1066486291, states[0] = -95.017085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078282996, states[0] = -94.936226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090173223, states[0] = -94.688405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102090744, states[0] = -11.989835, states[40]= 0.001959
Saving checkpoint... 
Iteration: 1112603594, states[0] = -24.112486, states[40]= 0.000744
Saving checkpoint... 
Iteration: 1125889129, states[0] = -94.996228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137951117, states[0] = -95.011556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151055394, states[0] = 9.068741, states[40]= 0.004913
Saving checkpoint... 
Iteration: 1164304640, states[0] = -94.953922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177553071, states[0] = 10.018845, states[40]= 0.004945
Saving checkpoint... 
Iteration: 1189920090, states[0] = -95.004943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203089134, states[0] = -10.550630, states[40]= 0.002235
Saving checkpoint... 
Iteration: 1216236375, states[0] = -94.881621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229296058, states[0] = -94.947299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242111634, states[0] = -31.780334, states[40]= 0.000384
Saving checkpoint... 
Iteration: 1255419401, states[0] = -95.004732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268055128, states[0] = 9.178580, states[40]= 0.004917
Saving checkpoint... 
Iteration: 1281427636, states[0] = -95.006662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294542182, states[0] = 14.252834, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1307727712, states[0] = -94.868283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321079963, states[0] = -3.388009, states[40]= 0.003726
Saving checkpoint... 
Iteration: 1334402737, states[0] = -95.000253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346550756, states[0] = 10.947342, states[40]= 0.004977
Saving checkpoint... 
Iteration: 1359840106, states[0] = -94.975771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373337934, states[0] = -94.974624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386615632, states[0] = -35.635647, states[40]= 0.000238
Saving checkpoint... 
Iteration: 1400002526, states[0] = 40.323041, states[40]= 0.119847
Saving checkpoint... 
Iteration: 1413000329, states[0] = -54.448952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426325046, states[0] = -94.967318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439543251, states[0] = 13.851600, states[40]= 0.005138
Saving checkpoint... 
Iteration: 1451738870, states[0] = -94.885084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464561600, states[0] = 6.416504, states[40]= 0.004812
Saving checkpoint... 
Iteration: 1477724616, states[0] = -94.863149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490813711, states[0] = -94.960078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503722706, states[0] = -62.446747, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1516274568, states[0] = -9.329667, states[40]= 0.002774
Saving checkpoint... 
Iteration: 1529304579, states[0] = -95.160905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542478705, states[0] = -95.117465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554726848, states[0] = -72.635286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1567973117, states[0] = -95.114677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581171022, states[0] = -95.112384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594117898, states[0] = -95.207719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607148335, states[0] = 8.037904, states[40]= 0.005646
Saving checkpoint... 
Iteration: 1619175528, states[0] = -12.222855, states[40]= 0.002166
Saving checkpoint... 
Iteration: 1631770443, states[0] = -7.141119, states[40]= 0.003331
Saving checkpoint... 
Iteration: 1644757602, states[0] = -95.076101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657962636, states[0] = -95.094655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671228628, states[0] = -95.226436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684352064, states[0] = -95.031863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697221615, states[0] = -65.850546, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1708472669, states[0] = -95.273943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720511276, states[0] = 23.307288, states[40]= 0.040209
Saving checkpoint... 
Iteration: 1732771249, states[0] = -95.272771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745636018, states[0] = -95.236266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758688437, states[0] = -26.453848, states[40]= 0.000630
Saving checkpoint... 
Iteration: 1771837361, states[0] = 13.577952, states[40]= 0.006261
Saving checkpoint... 
Iteration: 1784688950, states[0] = -95.286472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797712311, states[0] = -53.787507, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1810143397, states[0] = -70.500225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1824339072, states[0] = -95.007922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839984560, states[0] = -95.037369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855527454, states[0] = 19.060012, states[40]= 0.006474
Saving checkpoint... 
Iteration: 1871218282, states[0] = -94.860678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882251027, states[0] = -94.907279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894056020, states[0] = 8.727047, states[40]= 0.004905
Saving checkpoint... 
Iteration: 1905780707, states[0] = -94.936565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918091854, states[0] = -13.116521, states[40]= 0.001762
Saving checkpoint... 
Iteration: 1931206043, states[0] = -94.830993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944542277, states[0] = 14.202680, states[40]= 0.005170
Saving checkpoint... 
Iteration: 1956429443, states[0] = -95.007253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968984052, states[0] = -95.016612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981808938, states[0] = -94.956745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995176448, states[0] = -94.741970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008105017, states[0] = -25.473951, states[40]= 0.000681
Saving checkpoint... 
Iteration: 2020687952, states[0] = -94.791938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033181253, states[0] = -94.772557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046039912, states[0] = 15.091375, states[40]= 0.005264
Saving checkpoint... 
Iteration: 2058200900, states[0] = -94.819348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071153237, states[0] = -80.403681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084492222, states[0] = -95.017137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097102614, states[0] = -23.180743, states[40]= 0.000789
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893928
 - CaMKt in component CaMK (millimolar): 0.006997
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.592841
 - nass in component intracellular_ions (millimolar): 6.592901
 - ki in component intracellular_ions (millimolar): 145.383777
 - kss in component intracellular_ions (millimolar): 145.383758
 - cansr in component intracellular_ions (millimolar): 1.315638
 - cajsr in component intracellular_ions (millimolar): 1.277801
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879863
 - hs in component INa (dimensionless): 0.879859
 - j in component INa (dimensionless): 0.879830
 - hsp in component INa (dimensionless): 0.725571
 - jp in component INa (dimensionless): 0.879811
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710048
 - hLp in component INaL (dimensionless): 0.452794
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622712
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697946
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936632
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001619
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327991
 - xs1 in component IKs (dimensionless): 0.238497
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:15:48 (3684): called boinc_finish(0)

</stderr_txt>
]]>


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