𝕏

Task 55911364

Name HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_77_0
Workunit 26551322
Created 3 Jul 2024, 12:34:09 UTC
Sent 3 Jul 2024, 14:09:24 UTC
Report deadline 6 Jul 2024, 23:45:24 UTC
Received 6 Jul 2024, 3:10:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 32 min 53 sec
CPU time 2 hours 31 min 16 sec
Validate state Valid
Credit 61.02
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_77.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_77_0_r1944546977_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_77_0_r1944546977_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.825462
     * GNaL_b in INaL: 0.005969
     * Gto_b in Ito: 0.081756
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032300
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.162466
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.369376
     * GKb_b in IKb: 0.003823
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034884
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15985724, states[0] = -95.086428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31540764, states[0] = 14.478726, states[40]= 0.005282
Saving checkpoint... 
Iteration: 45836219, states[0] = -95.000469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61652945, states[0] = -81.949872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76767556, states[0] = -94.932434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92775983, states[0] = -94.937128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109472979, states[0] = -95.019435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124937075, states[0] = -95.011750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140908048, states[0] = -95.003969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159134481, states[0] = -55.216373, states[40]= 0.000012
Saving checkpoint... 
Iteration: 174132169, states[0] = -52.620171, states[40]= 0.000018
Saving checkpoint... 
Iteration: 189826569, states[0] = -94.969651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208460959, states[0] = -95.013882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226416245, states[0] = -95.004645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244961986, states[0] = -95.013888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259792710, states[0] = -94.945698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275658238, states[0] = -88.589349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291338454, states[0] = -94.975820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309903436, states[0] = -95.001077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325518416, states[0] = 21.714814, states[40]= 0.011534
Saving checkpoint... 
Iteration: 339558482, states[0] = 8.020096, states[40]= 0.004896
Saving checkpoint... 
Iteration: 355198058, states[0] = -94.816158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371314694, states[0] = -94.961786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387161087, states[0] = -91.672447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404108213, states[0] = -28.211216, states[40]= 0.000549
Saving checkpoint... 
Iteration: 421460693, states[0] = -95.013494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436598552, states[0] = -18.973353, states[40]= 0.001044
Saving checkpoint... 
Iteration: 452757093, states[0] = -94.910264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467756052, states[0] = -94.909018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484115581, states[0] = -35.326318, states[40]= 0.000247
Saving checkpoint... 
Iteration: 499940652, states[0] = -95.009806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515295019, states[0] = -94.947365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531155143, states[0] = -83.752272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546258687, states[0] = -94.912074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560934123, states[0] = -95.008428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577385178, states[0] = -94.995289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592529483, states[0] = 18.906724, states[40]= 0.006249
Saving checkpoint... 
Iteration: 609582947, states[0] = -5.188689, states[40]= 0.003372
Saving checkpoint... 
Iteration: 625389936, states[0] = -94.996815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642439919, states[0] = -95.009571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657676191, states[0] = -94.739039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672985002, states[0] = -95.016921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687355632, states[0] = -94.983821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703921776, states[0] = -95.005570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720007247, states[0] = 25.134637, states[40]= 0.098868
Saving checkpoint... 
Iteration: 736662003, states[0] = -92.349169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752976326, states[0] = -95.015686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767703539, states[0] = -94.826795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781954833, states[0] = -95.012275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797713992, states[0] = -94.846382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811920224, states[0] = -95.005131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827968698, states[0] = -95.014513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847081519, states[0] = -4.160285, states[40]= 0.003580
Saving checkpoint... 
Iteration: 864619807, states[0] = -39.505184, states[40]= 0.000138
Saving checkpoint... 
Iteration: 880998981, states[0] = -95.018507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897482212, states[0] = -95.016411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914017774, states[0] = 21.840899, states[40]= 0.012434
Saving checkpoint... 
Iteration: 930867989, states[0] = -94.988828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949040940, states[0] = 14.987485, states[40]= 0.005272
Saving checkpoint... 
Iteration: 965869044, states[0] = -94.989219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983671285, states[0] = -94.614464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002519363, states[0] = 21.522408, states[40]= 0.010447
Saving checkpoint... 
Iteration: 1018823309, states[0] = -94.966824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035414693, states[0] = -95.003624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050619208, states[0] = -38.905403, states[40]= 0.000150
Saving checkpoint... 
Iteration: 1065563968, states[0] = 5.595426, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1081532064, states[0] = 18.093747, states[40]= 0.005910
Saving checkpoint... 
Iteration: 1098510821, states[0] = 23.230155, states[40]= 0.043620
Saving checkpoint... 
Iteration: 1113933695, states[0] = -95.007992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129747503, states[0] = -94.897933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144983243, states[0] = -95.016395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160219777, states[0] = -94.856299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175206900, states[0] = -94.833016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191518581, states[0] = 21.682079, states[40]= 0.011325
Saving checkpoint... 
Iteration: 1209589627, states[0] = -10.634449, states[40]= 0.002218
Saving checkpoint... 
Iteration: 1227106527, states[0] = -26.596237, states[40]= 0.000626
Saving checkpoint... 
Iteration: 1242621158, states[0] = -40.868251, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1258876322, states[0] = -94.991775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275170400, states[0] = -94.566210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291078903, states[0] = -2.396900, states[40]= 0.003906
Saving checkpoint... 
Iteration: 1307279631, states[0] = -94.933507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322805626, states[0] = -94.954934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339919172, states[0] = -95.004547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356383702, states[0] = -94.994306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372346450, states[0] = -94.979145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386530960, states[0] = 18.447651, states[40]= 0.006042
Saving checkpoint... 
Iteration: 1402278614, states[0] = -94.932489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417665346, states[0] = -93.841138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432499056, states[0] = -95.018172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449355089, states[0] = -94.983104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464876285, states[0] = -94.991633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480614551, states[0] = -34.321873, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1496014232, states[0] = 22.492978, states[40]= 0.021417
Saving checkpoint... 
Iteration: 1512989200, states[0] = -24.375804, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1528602078, states[0] = -39.558514, states[40]= 0.000139
Saving checkpoint... 
Iteration: 1545375076, states[0] = -10.698143, states[40]= 0.002488
Saving checkpoint... 
Iteration: 1562166558, states[0] = -3.169104, states[40]= 0.004237
Saving checkpoint... 
Iteration: 1579786628, states[0] = -95.285456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594630999, states[0] = -80.817417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610957214, states[0] = -95.264344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627705744, states[0] = -95.196865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643702002, states[0] = 45.427024, states[40]= 0.071522
Saving checkpoint... 
Iteration: 1658870210, states[0] = -95.122371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674528903, states[0] = -95.233428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689603110, states[0] = 37.858310, states[40]= 0.111710
Saving checkpoint... 
Iteration: 1705998279, states[0] = -95.184402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723360112, states[0] = -95.093585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739173101, states[0] = -9.463062, states[40]= 0.002779
Saving checkpoint... 
Iteration: 1758080596, states[0] = -17.478119, states[40]= 0.001312
Saving checkpoint... 
Iteration: 1772177707, states[0] = -14.309131, states[40]= 0.001776
Saving checkpoint... 
Iteration: 1786970171, states[0] = -95.122620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803387173, states[0] = -95.052957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818011704, states[0] = 22.731583, states[40]= 0.035438
Saving checkpoint... 
Iteration: 1833961897, states[0] = -95.038877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849591956, states[0] = -13.613474, states[40]= 0.001687
Saving checkpoint... 
Iteration: 1865274420, states[0] = -94.938601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880419951, states[0] = -95.010989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896227704, states[0] = -94.873120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911407493, states[0] = -95.003808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929480508, states[0] = -95.017055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946108515, states[0] = -28.557190, states[40]= 0.000532
Saving checkpoint... 
Iteration: 1961432881, states[0] = -95.007853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976382400, states[0] = -94.993819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992943267, states[0] = -95.009580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009067548, states[0] = 3.902440, states[40]= 0.004673
Saving checkpoint... 
Iteration: 2025446806, states[0] = -95.010085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042672212, states[0] = -94.652368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058461474, states[0] = -95.012582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073851992, states[0] = -94.981283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091287855, states[0] = -94.940375, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893695
 - CaMKt in component CaMK (millimolar): 0.006924
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.611035
 - nass in component intracellular_ions (millimolar): 6.611095
 - ki in component intracellular_ions (millimolar): 145.367066
 - kss in component intracellular_ions (millimolar): 145.367046
 - cansr in component intracellular_ions (millimolar): 1.310185
 - cajsr in component intracellular_ions (millimolar): 1.272407
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879859
 - hs in component INa (dimensionless): 0.879855
 - j in component INa (dimensionless): 0.879826
 - hsp in component INa (dimensionless): 0.725564
 - jp in component INa (dimensionless): 0.879807
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710047
 - hLp in component INaL (dimensionless): 0.452785
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622562
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697606
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935683
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001597
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331360
 - xs1 in component IKs (dimensionless): 0.239779
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:10:40 (53659): called boinc_finish(0)

</stderr_txt>
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