𝕏

Task 55910062

Name HuVeMOp_20240703143056906080_ORdGradInc_k_26-Drouin_EPI_5000-conf_674_1
Workunit 26550672
Created 3 Jul 2024, 12:33:26 UTC
Sent 3 Jul 2024, 13:59:07 UTC
Report deadline 6 Jul 2024, 13:59:07 UTC
Received 4 Jul 2024, 19:47:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 5 min 27 sec
CPU time 1 hours 23 min 17 sec
Validate state Valid
Credit 46.34
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.69 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Drouin_EPI_5000-conf_674.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Drouin_EPI_5000-conf_674_1_r382115942_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Drouin_EPI_5000-conf_674_1_r382115942_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.455627
     * GNaL_b in INaL: 0.006040
     * Gto_b in Ito: 0.087449
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031691
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.161241
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.417253
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031455
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8334690, states[0] = -94.370867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16368007, states[0] = -94.295836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24712002, states[0] = -94.246230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33015421, states[0] = -94.245157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40311539, states[0] = -94.044580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48394030, states[0] = -94.241237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56765743, states[0] = -94.213647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64751671, states[0] = -94.207448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71955285, states[0] = -94.212142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79775925, states[0] = -94.209806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88148938, states[0] = -94.251256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96175222, states[0] = -94.235335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103536903, states[0] = -94.241982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111984653, states[0] = -94.218972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119709205, states[0] = -94.217133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127879096, states[0] = -94.163514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136456288, states[0] = -94.231587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144778570, states[0] = -94.218426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152633721, states[0] = -24.426567, states[40]= 0.000418
Saving checkpoint... 
Iteration: 161399831, states[0] = -94.234339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169872810, states[0] = -94.218475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177182712, states[0] = -94.220550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185873181, states[0] = -94.254392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193815211, states[0] = -94.237407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201780444, states[0] = -94.226502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210190125, states[0] = -92.033858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217498213, states[0] = -94.217843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226396600, states[0] = -94.235084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234701956, states[0] = -94.220578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242415865, states[0] = -94.218449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250450214, states[0] = -94.221657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259217250, states[0] = -94.227504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267915062, states[0] = -94.199482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275810808, states[0] = -94.256734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284298451, states[0] = -94.225840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292489967, states[0] = -94.217463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301087771, states[0] = -94.244958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309371715, states[0] = -94.224405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317946796, states[0] = -94.219324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326889803, states[0] = -94.223959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335215284, states[0] = -93.606328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343614127, states[0] = -94.243533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351695444, states[0] = -94.227113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359374617, states[0] = -94.223887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367025461, states[0] = -94.221617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375062367, states[0] = 22.041834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383311224, states[0] = -94.255726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391713541, states[0] = -94.226374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400013454, states[0] = 22.257866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407919911, states[0] = -94.201766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416448315, states[0] = -94.232077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424747672, states[0] = -94.218422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433205854, states[0] = -94.258036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442177722, states[0] = -94.219008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450357629, states[0] = -94.136459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458856910, states[0] = -94.234189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466080850, states[0] = -94.243642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474084735, states[0] = -94.228217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481942159, states[0] = -94.221652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489975888, states[0] = -94.215670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498247839, states[0] = -94.256623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505512356, states[0] = -94.241989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513617719, states[0] = -94.241730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521807964, states[0] = -94.223388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529495976, states[0] = -94.220419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537492324, states[0] = -94.215071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545422749, states[0] = -94.202423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553669452, states[0] = -94.239397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562736923, states[0] = -93.747579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570829583, states[0] = -94.253183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578820639, states[0] = -94.234094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586869001, states[0] = -94.221739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595543515, states[0] = -94.247499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603573494, states[0] = -94.242584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612187411, states[0] = -94.217224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620306195, states[0] = -94.032536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628108388, states[0] = -94.254217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635866365, states[0] = -94.251046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644121105, states[0] = -94.225750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652657369, states[0] = -50.910999, states[40]= 0.000097
Saving checkpoint... 
Iteration: 661132277, states[0] = -94.239719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669757079, states[0] = -94.215906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677900553, states[0] = -94.183556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685985176, states[0] = -94.245445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694239074, states[0] = -94.222911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702405738, states[0] = -94.214166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710609615, states[0] = -94.253479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718736376, states[0] = -94.235419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727062431, states[0] = -94.217583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735361430, states[0] = -94.139041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743274013, states[0] = -94.253470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751364548, states[0] = -94.231085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759335950, states[0] = -94.220573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767495085, states[0] = -94.212778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775797431, states[0] = -94.252370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783239125, states[0] = -94.254031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791670575, states[0] = -94.223275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799421946, states[0] = -94.218823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807263651, states[0] = -94.214484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814560440, states[0] = -94.216749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822703196, states[0] = -93.492640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830874294, states[0] = -94.248797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839525841, states[0] = -94.216955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847740910, states[0] = -93.768046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855522544, states[0] = -94.240919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863156518, states[0] = -94.253710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871865599, states[0] = -94.218981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880206138, states[0] = -93.526497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888870865, states[0] = -94.229549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897079723, states[0] = -94.215689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905344322, states[0] = -94.111063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913662869, states[0] = -94.236092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921383884, states[0] = -94.228857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929366144, states[0] = -94.218405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937401190, states[0] = -94.211889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945962355, states[0] = -94.243871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954504396, states[0] = -94.216112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963019874, states[0] = -94.239270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970763557, states[0] = -94.251553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979317082, states[0] = -94.218722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987793918, states[0] = -93.993816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995994696, states[0] = -94.241992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004052908, states[0] = -94.223717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011665638, states[0] = -94.221207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019635471, states[0] = -94.213803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027341484, states[0] = -94.211549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035138883, states[0] = -29.967863, states[40]= 0.000499
Saving checkpoint... 
Iteration: 1043283398, states[0] = -94.250222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051045285, states[0] = -94.239328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059019668, states[0] = -94.223957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067558319, states[0] = 23.228386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076262831, states[0] = -94.231020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083897137, states[0] = -94.226883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091871066, states[0] = -94.216725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100033665, states[0] = 26.380403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108260784, states[0] = -94.250278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116718261, states[0] = -94.219138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124720045, states[0] = -94.211809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132796454, states[0] = -94.000039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141379771, states[0] = -94.226805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150069478, states[0] = 19.611960, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1158674540, states[0] = -94.233253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167566886, states[0] = 20.548008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176535910, states[0] = -94.222410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185266176, states[0] = -93.890681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194276254, states[0] = -94.217308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202799479, states[0] = -94.008190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211234671, states[0] = -94.230629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220323883, states[0] = -94.068855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229472667, states[0] = -94.213841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237527595, states[0] = 25.855205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246773614, states[0] = -94.216839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255810835, states[0] = -94.247164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264419142, states[0] = -94.214279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272206340, states[0] = -94.210504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279436348, states[0] = -94.213874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287280233, states[0] = -94.209580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294901537, states[0] = -94.208359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302915059, states[0] = -94.189356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310464294, states[0] = -94.218009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319157717, states[0] = -94.218333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326749779, states[0] = -94.216478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334475884, states[0] = -94.212758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342361493, states[0] = -94.208250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350400497, states[0] = -94.176869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358567270, states[0] = -94.235401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367166272, states[0] = -94.210012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375609964, states[0] = -94.246964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384001642, states[0] = -94.221189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392013765, states[0] = -94.211666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399996006, states[0] = -94.206527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408469302, states[0] = -94.239016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416847309, states[0] = -94.213900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425321840, states[0] = -94.062369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433438977, states[0] = -94.240084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440783424, states[0] = -94.246310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449063207, states[0] = -94.219091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456536921, states[0] = -94.219627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464281642, states[0] = -94.214550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471993514, states[0] = -94.211156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480376302, states[0] = -94.150708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488599733, states[0] = -94.232829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496549724, states[0] = -94.218933, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.081485
 - CaMKt in component CaMK (millimolar): 0.001703
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.053191
 - nass in component intracellular_ions (millimolar): 7.053327
 - ki in component intracellular_ions (millimolar): 144.642585
 - kss in component intracellular_ions (millimolar): 144.642572
 - cansr in component intracellular_ions (millimolar): 2.398986
 - cajsr in component intracellular_ions (millimolar): 2.399351
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003931
 - hf in component INa (dimensionless): 0.865020
 - hs in component INa (dimensionless): 0.865020
 - j in component INa (dimensionless): 0.865022
 - hsp in component INa (dimensionless): 0.698234
 - jp in component INa (dimensionless): 0.865023
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707015
 - hLp in component INaL (dimensionless): 0.513209
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999850
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998798
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005337
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001782
 - xs1 in component IKs (dimensionless): 0.023624
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:00:00 (74784): called boinc_finish(0)

</stderr_txt>
]]>


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