𝕏

Task 55909340

Name HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767_0
Workunit 26550312
Created 3 Jul 2024, 12:33:00 UTC
Sent 3 Jul 2024, 13:51:10 UTC
Report deadline 6 Jul 2024, 23:27:10 UTC
Received 3 Jul 2024, 20:30:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239941
Run time 2 hours 45 min 53 sec
CPU time 1 hours 41 min 15 sec
Validate state Valid
Credit 65.32
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.80 MB
Peak swap size 391.76 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767_0_r1886186181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767_0_r1886186181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.730114
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.082405
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031559
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.164484
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.669967
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034155
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 21843963, states[0] = -95.031763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48154434, states[0] = -83.933634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70676551, states[0] = -94.749897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93317664, states[0] = -94.962288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116309953, states[0] = -94.953879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139365683, states[0] = -94.981791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162275326, states[0] = -94.922820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184034323, states[0] = 17.256887, states[40]= 0.005678
Saving checkpoint... 
Iteration: 208886616, states[0] = -94.987888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231702621, states[0] = -94.817726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253124263, states[0] = -43.246101, states[40]= 0.000079
Saving checkpoint... 
Iteration: 277240726, states[0] = -94.881335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299990075, states[0] = -95.009466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322789334, states[0] = -94.934609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345036219, states[0] = 16.614044, states[40]= 0.005527
Saving checkpoint... 
Iteration: 367725895, states[0] = -94.859033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391774792, states[0] = -94.921280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414761536, states[0] = -94.907316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437499349, states[0] = -95.010475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460902696, states[0] = -94.992428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483569375, states[0] = 3.079151, states[40]= 0.004588
Saving checkpoint... 
Iteration: 506872661, states[0] = -94.982575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527722845, states[0] = -94.853956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552256219, states[0] = -94.901080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574811266, states[0] = -94.951124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597316149, states[0] = -94.954352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620190372, states[0] = -94.792242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642922555, states[0] = -94.997450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665797480, states[0] = -94.941016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688952065, states[0] = -95.003496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710774617, states[0] = -94.920910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735901810, states[0] = -94.992007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758808264, states[0] = -94.948938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781321430, states[0] = -94.957573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803878923, states[0] = -94.984675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826402140, states[0] = -94.992045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849860772, states[0] = -94.977638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872556124, states[0] = 9.009884, states[40]= 0.004914
Saving checkpoint... 
Iteration: 899275988, states[0] = -94.922133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923181836, states[0] = -94.767725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945733738, states[0] = -94.870823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964978618, states[0] = -95.007529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989879689, states[0] = -94.984831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012117944, states[0] = -36.957939, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1033722038, states[0] = -94.852302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053666428, states[0] = -93.848731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076512474, states[0] = 22.708209, states[40]= 0.030394
Saving checkpoint... 
Iteration: 1101889682, states[0] = -94.988114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125065124, states[0] = 5.107030, states[40]= 0.004736
Saving checkpoint... 
Iteration: 1147630072, states[0] = -49.304189, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1169773662, states[0] = -94.919681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192625199, states[0] = -44.199640, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1214763118, states[0] = -94.908586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235681644, states[0] = -94.766687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263111051, states[0] = -30.342821, states[40]= 0.000447
Saving checkpoint... 
Iteration: 1287581954, states[0] = -4.248453, states[40]= 0.003546
Saving checkpoint... 
Iteration: 1311911818, states[0] = -94.994380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336549158, states[0] = 11.800641, states[40]= 0.005022
Saving checkpoint... 
Iteration: 1361023271, states[0] = 20.530339, states[40]= 0.007851
Saving checkpoint... 
Iteration: 1385738997, states[0] = -94.878192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409234015, states[0] = -94.870949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435874384, states[0] = -94.982645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452660476, states[0] = -90.004199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498403361, states[0] = -94.991977, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767_0_r1886186181_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_767_0_r1886186181_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.730114
     * GNaL_b in INaL: 0.005610
     * Gto_b in Ito: 0.082405
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031559
     * GKs_b in IKs: 0.001909
     * GK1_b in IK1: 0.164484
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.669967
     * GKb_b in IKb: 0.003825
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034155
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1498403361
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.991977 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1517705355, states[0] = 29.309940, states[40]= 0.117573
Saving checkpoint... 
Iteration: 1538155157, states[0] = 4.878613, states[40]= 0.005351
Saving checkpoint... 
Iteration: 1557149668, states[0] = -94.905312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578038409, states[0] = 13.380035, states[40]= 0.006225
Saving checkpoint... 
Iteration: 1598248826, states[0] = -94.897332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618974532, states[0] = -95.119491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638080505, states[0] = -16.891361, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1660138304, states[0] = -95.232257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680608199, states[0] = 25.187950, states[40]= 0.077201
Saving checkpoint... 
Iteration: 1700297400, states[0] = -95.169952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724283411, states[0] = -95.141361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747053481, states[0] = -95.034855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770586238, states[0] = -95.277642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792244039, states[0] = 10.500161, states[40]= 0.005872
Saving checkpoint... 
Iteration: 1813649995, states[0] = -78.790725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838020276, states[0] = 21.013874, states[40]= 0.009543
Saving checkpoint... 
Iteration: 1861259609, states[0] = -94.915576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884029939, states[0] = 18.608883, states[40]= 0.006173
Saving checkpoint... 
Iteration: 1907392027, states[0] = -94.991168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931098147, states[0] = -18.209391, states[40]= 0.001106
Saving checkpoint... 
Iteration: 1954458694, states[0] = -95.004527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977639950, states[0] = -60.208344, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1999486365, states[0] = -95.008070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023177872, states[0] = -94.741194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046287151, states[0] = -94.931661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069530076, states[0] = 18.634777, states[40]= 0.006158
Saving checkpoint... 
Iteration: 2093748562, states[0] = -94.890619, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.885358
 - CaMKt in component CaMK (millimolar): 0.006893
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.576138
 - nass in component intracellular_ions (millimolar): 6.576197
 - ki in component intracellular_ions (millimolar): 145.402796
 - kss in component intracellular_ions (millimolar): 145.402777
 - cansr in component intracellular_ions (millimolar): 1.306718
 - cajsr in component intracellular_ions (millimolar): 1.268883
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879714
 - hs in component INa (dimensionless): 0.879710
 - j in component INa (dimensionless): 0.879681
 - hsp in component INa (dimensionless): 0.725291
 - jp in component INa (dimensionless): 0.879662
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709579
 - hLp in component INaL (dimensionless): 0.451794
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621551
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696450
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935634
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331774
 - xs1 in component IKs (dimensionless): 0.240468
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:25:21 (8610): called boinc_finish(0)

</stderr_txt>
]]>


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