𝕏

Task 55906775

Name HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_327_1
Workunit 26549032
Created 3 Jul 2024, 12:31:36 UTC
Sent 3 Jul 2024, 13:42:33 UTC
Report deadline 6 Jul 2024, 23:18:33 UTC
Received 4 Jul 2024, 21:43:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224229
Run time 2 hours 43 min 57 sec
CPU time 2 hours 11 min 18 sec
Validate state Valid
Credit 62.02
Device peak FLOPS 5.85 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 3.13 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_327.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_327_1_r1713681846_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703143056906080_ORdGradInc_k_26-Pueyo_APDR-conf_327_1_r1713681846_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.858092
     * GNaL_b in INaL: 0.006192
     * Gto_b in Ito: 0.087262
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031731
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.161169
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.088337
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031505
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18620687, states[0] = -41.589201, states[40]= 0.000101
Saving checkpoint... 
Iteration: 35779175, states[0] = -94.965101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53643174, states[0] = -63.187792, states[40]= 0.000003
Saving checkpoint... 
Iteration: 70846409, states[0] = -94.986666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88191753, states[0] = -94.796023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104721578, states[0] = -94.852403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117482540, states[0] = -95.015456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130575336, states[0] = 0.774382, states[40]= 0.004326
Saving checkpoint... 
Iteration: 143747979, states[0] = -94.890055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157159795, states[0] = -85.758460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170010294, states[0] = 22.893644, states[40]= 0.049607
Saving checkpoint... 
Iteration: 182816656, states[0] = -94.956224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195460488, states[0] = -95.008980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208057975, states[0] = 8.847873, states[40]= 0.004851
Saving checkpoint... 
Iteration: 220627118, states[0] = -43.918626, states[40]= 0.000074
Saving checkpoint... 
Iteration: 233208981, states[0] = -94.824104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246497374, states[0] = -95.014093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260072252, states[0] = 2.449583, states[40]= 0.004500
Saving checkpoint... 
Iteration: 272904346, states[0] = -94.995829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285830479, states[0] = -94.964472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298563806, states[0] = 6.399686, states[40]= 0.004763
Saving checkpoint... 
Iteration: 310902477, states[0] = -94.995229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323442185, states[0] = -95.005113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335479212, states[0] = -95.011544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347522299, states[0] = 20.796155, states[40]= 0.008055
Saving checkpoint... 
Iteration: 359328596, states[0] = -94.963277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370422673, states[0] = -95.000670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381718649, states[0] = -94.842060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393036914, states[0] = 16.688986, states[40]= 0.005352
Saving checkpoint... 
Iteration: 404420988, states[0] = -95.000227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415885474, states[0] = -94.989652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427168987, states[0] = -93.840873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439633500, states[0] = -50.612060, states[40]= 0.000026
Saving checkpoint... 
Iteration: 452181988, states[0] = -94.751086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465078503, states[0] = -0.954958, states[40]= 0.004095
Saving checkpoint... 
Iteration: 478065365, states[0] = 5.712142, states[40]= 0.004730
Saving checkpoint... 
Iteration: 491288267, states[0] = -94.933259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504372771, states[0] = -94.984872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517779355, states[0] = -94.924824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531031102, states[0] = 18.531087, states[40]= 0.005856
Saving checkpoint... 
Iteration: 543796521, states[0] = -94.940371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556529747, states[0] = 18.926331, states[40]= 0.006032
Saving checkpoint... 
Iteration: 569498564, states[0] = -95.013954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582732635, states[0] = -94.865634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596277162, states[0] = -94.922581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609106966, states[0] = -24.583071, states[40]= 0.000736
Saving checkpoint... 
Iteration: 621795276, states[0] = -94.939280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634533699, states[0] = 17.735002, states[40]= 0.005589
Saving checkpoint... 
Iteration: 647208151, states[0] = -94.822097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659809541, states[0] = -94.950427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672205030, states[0] = -94.815885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684190656, states[0] = -94.784874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695897540, states[0] = -94.993459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707381830, states[0] = -94.988164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718596299, states[0] = -14.662966, states[40]= 0.001507
Saving checkpoint... 
Iteration: 729945043, states[0] = -95.005420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741073386, states[0] = 1.870753, states[40]= 0.004444
Saving checkpoint... 
Iteration: 752200129, states[0] = -94.805819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763531160, states[0] = 18.513891, states[40]= 0.005849
Saving checkpoint... 
Iteration: 775834262, states[0] = -94.966329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788795205, states[0] = -94.939111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801771476, states[0] = -94.916530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814401187, states[0] = -94.994502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828370017, states[0] = -94.983560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844818332, states[0] = -94.956439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865062616, states[0] = 6.915173, states[40]= 0.004785
Saving checkpoint... 
Iteration: 883946916, states[0] = -95.005692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903189247, states[0] = -94.781103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920191713, states[0] = -94.787286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935034505, states[0] = 17.478647, states[40]= 0.005522
Saving checkpoint... 
Iteration: 953333137, states[0] = -94.965567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974372698, states[0] = -94.984536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994181851, states[0] = -94.749713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010699582, states[0] = -94.804508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026362962, states[0] = -94.980475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043247903, states[0] = -94.887815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058069498, states[0] = 3.804432, states[40]= 0.004611
Saving checkpoint... 
Iteration: 1073320355, states[0] = -94.957627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090470491, states[0] = -95.009724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107947169, states[0] = -95.005596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124300095, states[0] = -94.942905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135298677, states[0] = -94.941754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146530836, states[0] = 18.609949, states[40]= 0.005888
Saving checkpoint... 
Iteration: 1157345592, states[0] = -94.972206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168328800, states[0] = -94.962868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179382592, states[0] = -94.988130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189981335, states[0] = -95.011286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200764551, states[0] = -94.908581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211963616, states[0] = -95.008523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225777509, states[0] = -94.922518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239452504, states[0] = -95.006532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253523369, states[0] = 20.562923, states[40]= 0.007570
Saving checkpoint... 
Iteration: 1266704840, states[0] = -94.815111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280628214, states[0] = -45.034341, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1294828279, states[0] = -94.962471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308776672, states[0] = -94.921617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321953509, states[0] = -95.006666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336021909, states[0] = 20.878275, states[40]= 0.008261
Saving checkpoint... 
Iteration: 1349564074, states[0] = 6.283109, states[40]= 0.004758
Saving checkpoint... 
Iteration: 1363529499, states[0] = 18.997206, states[40]= 0.006068
Saving checkpoint... 
Iteration: 1376352251, states[0] = -94.975362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389136714, states[0] = -54.095486, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1402468218, states[0] = -95.009158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413030124, states[0] = 18.818019, states[40]= 0.005980
Saving checkpoint... 
Iteration: 1425046326, states[0] = 13.354167, states[40]= 0.005000
Saving checkpoint... 
Iteration: 1436938158, states[0] = -95.003533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447195072, states[0] = -94.794583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458887828, states[0] = -94.989784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470398325, states[0] = -94.993198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481835084, states[0] = -94.966335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493317363, states[0] = -94.955364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502823912, states[0] = -60.485945, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1513021295, states[0] = -58.506493, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1523151673, states[0] = 7.565866, states[40]= 0.005504
Saving checkpoint... 
Iteration: 1533478403, states[0] = -95.107370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543426249, states[0] = -95.205708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551687668, states[0] = -22.608420, states[40]= 0.000857
Saving checkpoint... 
Iteration: 1561855531, states[0] = 4.958910, states[40]= 0.005338
Saving checkpoint... 
Iteration: 1573483005, states[0] = -95.278953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584256335, states[0] = -95.257032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595278008, states[0] = -95.129290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606543417, states[0] = 11.216556, states[40]= 0.005851
Saving checkpoint... 
Iteration: 1617210369, states[0] = -95.198108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628085017, states[0] = -95.286510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639386528, states[0] = -95.151904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651170942, states[0] = -95.275560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664961773, states[0] = -95.267214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679037945, states[0] = -95.240676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690821833, states[0] = 20.289200, states[40]= 0.009573
Saving checkpoint... 
Iteration: 1702477002, states[0] = -95.281176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714481832, states[0] = -95.285107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726622246, states[0] = -63.329336, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1738411240, states[0] = -95.201229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750325293, states[0] = -67.548218, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1761262309, states[0] = -95.268001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772655057, states[0] = -95.260653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783495624, states[0] = -95.295224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794495900, states[0] = -95.172573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805557391, states[0] = 7.944595, states[40]= 0.004923
Saving checkpoint... 
Iteration: 1816843405, states[0] = -95.013531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828360251, states[0] = -95.010055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838688232, states[0] = -94.801558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850045506, states[0] = 13.404178, states[40]= 0.005021
Saving checkpoint... 
Iteration: 1860709963, states[0] = -94.837057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872288502, states[0] = -94.941100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883650517, states[0] = -71.286283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1896260730, states[0] = -94.907821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908393304, states[0] = -94.994166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920319373, states[0] = -94.958420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931321191, states[0] = -94.959033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941874710, states[0] = -94.985711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955711535, states[0] = -94.828468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969794990, states[0] = -94.938574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983640850, states[0] = -58.713008, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1996267152, states[0] = -94.911171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008905825, states[0] = -94.995182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021706901, states[0] = -94.818772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034501031, states[0] = 48.867408, states[40]= 0.029179
Saving checkpoint... 
Iteration: 2047626139, states[0] = -42.913178, states[40]= 0.000086
Saving checkpoint... 
Iteration: 2061115251, states[0] = -32.335198, states[40]= 0.000370
Saving checkpoint... 
Iteration: 2074136452, states[0] = -53.810008, states[40]= 0.000015
Saving checkpoint... 
Iteration: 2088615851, states[0] = -32.900555, states[40]= 0.000346
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.888956
 - CaMKt in component CaMK (millimolar): 0.007062
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.571274
 - nass in component intracellular_ions (millimolar): 6.571334
 - ki in component intracellular_ions (millimolar): 145.405382
 - kss in component intracellular_ions (millimolar): 145.405362
 - cansr in component intracellular_ions (millimolar): 1.315561
 - cajsr in component intracellular_ions (millimolar): 1.277300
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879777
 - hs in component INa (dimensionless): 0.879772
 - j in component INa (dimensionless): 0.879742
 - hsp in component INa (dimensionless): 0.725408
 - jp in component INa (dimensionless): 0.879722
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709077
 - hLp in component INaL (dimensionless): 0.450129
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619137
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.693571
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934085
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001615
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334100
 - xs1 in component IKs (dimensionless): 0.244632
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:42:18 (880989): called boinc_finish(0)

</stderr_txt>
]]>


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