𝕏

Task 55905402

Name HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_518_2
Workunit 26517735
Created 3 Jul 2024, 11:55:23 UTC
Sent 3 Jul 2024, 13:34:21 UTC
Report deadline 6 Jul 2024, 23:10:21 UTC
Received 3 Jul 2024, 22:42:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 3 hours 54 min 59 sec
CPU time 2 hours 55 min 50 sec
Validate state Valid
Credit 61.71
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.63 MB
Peak swap size 32.63 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_518.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_518_2_r2014056978_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703070613691335_ORdGradInc_k_26-Pueyo_APDR-conf_518_2_r2014056978_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.675638
     * GNaL_b in INaL: 0.005782
     * Gto_b in Ito: 0.085467
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032255
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.162293
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.040806
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034849
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 2675119, states[0] = -94.926112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15615611, states[0] = -38.793803, states[40]= 0.000145
Saving checkpoint... 
Iteration: 28374252, states[0] = -95.049209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41075949, states[0] = -1.255627, states[40]= 0.004080
Saving checkpoint... 
Iteration: 55303288, states[0] = -94.983545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67741044, states[0] = -94.912126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83413567, states[0] = -95.022477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98862315, states[0] = -95.002127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112815082, states[0] = -94.975019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127214307, states[0] = -94.857049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141139498, states[0] = -59.962089, states[40]= 0.000005
Saving checkpoint... 
Iteration: 155150599, states[0] = -74.547647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169356999, states[0] = -94.994923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183300096, states[0] = -94.960959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197453760, states[0] = -95.022676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211666769, states[0] = -93.958936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224727038, states[0] = -94.876602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236927996, states[0] = -95.017227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247317193, states[0] = -94.972698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258925413, states[0] = -95.016571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274827685, states[0] = -94.979154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289043072, states[0] = 14.151253, states[40]= 0.005084
Saving checkpoint... 
Iteration: 303214566, states[0] = -94.854951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316710035, states[0] = -94.846537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330566366, states[0] = 4.632753, states[40]= 0.004673
Saving checkpoint... 
Iteration: 345034588, states[0] = 17.141152, states[40]= 0.005520
Saving checkpoint... 
Iteration: 358401757, states[0] = -95.010287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371862331, states[0] = -94.996400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386328904, states[0] = -94.979764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400847686, states[0] = -94.989750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414587059, states[0] = -7.984958, states[40]= 0.002751
Saving checkpoint... 
Iteration: 426941096, states[0] = -95.019814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437989321, states[0] = -95.027624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448726368, states[0] = -94.875222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459325250, states[0] = -94.977549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470116616, states[0] = -35.633266, states[40]= 0.000237
Saving checkpoint... 
Iteration: 481808234, states[0] = -94.966351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492518619, states[0] = 21.357204, states[40]= 0.010940
Saving checkpoint... 
Iteration: 504023610, states[0] = 20.310640, states[40]= 0.007460
Saving checkpoint... 
Iteration: 514611869, states[0] = -31.058546, states[40]= 0.000415
Saving checkpoint... 
Iteration: 531070774, states[0] = 2.485890, states[40]= 0.004508
Saving checkpoint... 
Iteration: 546006444, states[0] = 25.312151, states[40]= 0.117782
Saving checkpoint... 
Iteration: 560596384, states[0] = -16.340196, states[40]= 0.001292
Saving checkpoint... 
Iteration: 575147812, states[0] = -70.289528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588954891, states[0] = -95.022316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604747589, states[0] = -94.906434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620088481, states[0] = -9.168800, states[40]= 0.002500
Saving checkpoint... 
Iteration: 634173909, states[0] = -94.683260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646370213, states[0] = -94.999421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659996745, states[0] = -95.028396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674609620, states[0] = -28.909988, states[40]= 0.000515
Saving checkpoint... 
Iteration: 689313031, states[0] = -94.969562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704061305, states[0] = 6.908570, states[40]= 0.004789
Saving checkpoint... 
Iteration: 718299234, states[0] = -94.959470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732064477, states[0] = 5.502671, states[40]= 0.004723
Saving checkpoint... 
Iteration: 746283349, states[0] = -94.945985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760711376, states[0] = -94.848755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773179616, states[0] = -94.768816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784354413, states[0] = -94.992660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795560689, states[0] = 7.174667, states[40]= 0.004800
Saving checkpoint... 
Iteration: 806590883, states[0] = -11.260099, states[40]= 0.002079
Saving checkpoint... 
Iteration: 817753259, states[0] = -94.913589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828665385, states[0] = -93.541012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839754811, states[0] = -94.915499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851323489, states[0] = -94.976221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863481330, states[0] = -95.026284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875286992, states[0] = -94.949183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885717853, states[0] = -94.860450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896269434, states[0] = -94.932161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908056904, states[0] = 8.767625, states[40]= 0.004855
Saving checkpoint... 
Iteration: 921451817, states[0] = -95.021547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935179020, states[0] = -94.764395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950398067, states[0] = -95.008807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965324379, states[0] = -94.976691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978233626, states[0] = -94.886333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991415987, states[0] = -95.013746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003244603, states[0] = -94.902159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014013577, states[0] = 22.178814, states[40]= 0.023781
Saving checkpoint... 
Iteration: 1025004053, states[0] = 31.126813, states[40]= 0.156933
Saving checkpoint... 
Iteration: 1036000569, states[0] = 20.698557, states[40]= 0.000940
Saving checkpoint... 
Iteration: 1047186675, states[0] = -94.796922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058366092, states[0] = -94.997508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069159912, states[0] = -89.449984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079748962, states[0] = -94.907929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090545678, states[0] = 13.178858, states[40]= 0.005016
Saving checkpoint... 
Iteration: 1101666850, states[0] = -93.973748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112842731, states[0] = -94.986822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128490450, states[0] = -95.027317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142708912, states[0] = -94.843855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156893620, states[0] = -95.007305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171047337, states[0] = 12.550282, states[40]= 0.004983
Saving checkpoint... 
Iteration: 1185072196, states[0] = 1.751097, states[40]= 0.004437
Saving checkpoint... 
Iteration: 1199588840, states[0] = -9.474163, states[40]= 0.002436
Saving checkpoint... 
Iteration: 1213670103, states[0] = -94.474328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227932888, states[0] = -95.017573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241968562, states[0] = -95.024163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256058529, states[0] = 8.092130, states[40]= 0.004833
Saving checkpoint... 
Iteration: 1267955325, states[0] = -95.021951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278957447, states[0] = -95.022314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289050500, states[0] = 11.331394, states[40]= 0.004933
Saving checkpoint... 
Iteration: 1300532837, states[0] = 17.711300, states[40]= 0.005673
Saving checkpoint... 
Iteration: 1311685801, states[0] = -94.794370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322830160, states[0] = -94.979879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334302398, states[0] = -94.961502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345619911, states[0] = -38.866252, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1356874941, states[0] = -95.000767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368175594, states[0] = -94.722488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379831593, states[0] = -94.980660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392504155, states[0] = 30.721189, states[40]= 0.156973
Saving checkpoint... 
Iteration: 1405886149, states[0] = -95.004714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419864510, states[0] = -94.996624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433519695, states[0] = 21.155359, states[40]= 0.009809
Saving checkpoint... 
Iteration: 1447075784, states[0] = -0.219418, states[40]= 0.004205
Saving checkpoint... 
Iteration: 1460935260, states[0] = -95.017932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474644130, states[0] = -65.394425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1488418507, states[0] = -95.014056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502578105, states[0] = -95.094778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515757408, states[0] = -95.034797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516814361, states[0] = 22.603743, states[40]= 0.022453
Saving checkpoint... 
Iteration: 1527648450, states[0] = 8.704439, states[40]= 0.005607
Saving checkpoint... 
Iteration: 1538999386, states[0] = -95.288369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549448997, states[0] = -95.251971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560392402, states[0] = -29.549866, states[40]= 0.000476
Saving checkpoint... 
Iteration: 1571101286, states[0] = 48.403820, states[40]= 0.038200
Saving checkpoint... 
Iteration: 1582377728, states[0] = -95.143623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594283223, states[0] = -19.866160, states[40]= 0.001055
Saving checkpoint... 
Iteration: 1605517625, states[0] = -95.224111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617032734, states[0] = 15.863630, states[40]= 0.006630
Saving checkpoint... 
Iteration: 1627753220, states[0] = -95.270995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638833797, states[0] = -95.248749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649575439, states[0] = -95.142980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659835032, states[0] = -95.250751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670811057, states[0] = -51.517810, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1681721894, states[0] = -95.232891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697647423, states[0] = -95.265807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711019612, states[0] = -62.356033, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1724602041, states[0] = -95.200162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739765634, states[0] = -2.595904, states[40]= 0.004329
Saving checkpoint... 
Iteration: 1754168379, states[0] = -4.832799, states[40]= 0.003856
Saving checkpoint... 
Iteration: 1769259648, states[0] = -95.098372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783501310, states[0] = 48.338461, states[40]= 0.039973
Saving checkpoint... 
Iteration: 1797221522, states[0] = -95.232452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810073837, states[0] = -0.738689, states[40]= 0.004224
Saving checkpoint... 
Iteration: 1824144239, states[0] = -68.780169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1838314125, states[0] = -94.992765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852806941, states[0] = -94.979675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867556440, states[0] = 8.775781, states[40]= 0.004862
Saving checkpoint... 
Iteration: 1881980404, states[0] = -95.031800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896381092, states[0] = -95.006762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910915647, states[0] = -95.015717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924250693, states[0] = -94.911427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938146027, states[0] = -67.961375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1952259380, states[0] = -94.921021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966374058, states[0] = -95.000513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980391520, states[0] = -95.006398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994183671, states[0] = -94.787536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008361734, states[0] = -94.995176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022395483, states[0] = -95.007365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036619774, states[0] = -38.734247, states[40]= 0.000154
Saving checkpoint... 
Iteration: 2050246575, states[0] = -94.904125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065031829, states[0] = 18.029820, states[40]= 0.005776
Saving checkpoint... 
Iteration: 2078806083, states[0] = -94.963716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093444633, states[0] = -95.019383, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903668
 - CaMKt in component CaMK (millimolar): 0.006985
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.585944
 - nass in component intracellular_ions (millimolar): 6.586004
 - ki in component intracellular_ions (millimolar): 145.391435
 - kss in component intracellular_ions (millimolar): 145.391415
 - cansr in component intracellular_ions (millimolar): 1.312085
 - cajsr in component intracellular_ions (millimolar): 1.274124
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880032
 - hs in component INa (dimensionless): 0.880028
 - j in component INa (dimensionless): 0.879999
 - hsp in component INa (dimensionless): 0.725890
 - jp in component INa (dimensionless): 0.879980
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710065
 - hLp in component INaL (dimensionless): 0.452346
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621717
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696727
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935823
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001601
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327674
 - xs1 in component IKs (dimensionless): 0.240698
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:06:19 (17529): called boinc_finish(0)

</stderr_txt>
]]>


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