𝕏

Task 55905245

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2_2
Workunit 26401577
Created 3 Jul 2024, 11:10:57 UTC
Sent 3 Jul 2024, 13:33:36 UTC
Report deadline 6 Jul 2024, 13:33:36 UTC
Received 5 Jul 2024, 22:45:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224115
Run time 1 hours 29 min 55 sec
CPU time 1 hours 14 min 42 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.81 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.02 MB
Peak swap size 391.88 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2_2_r298274821_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2_2_r298274821_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032321
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 26817305, states[0] = -86.714549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50535998, states[0] = 31.119621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65213988, states[0] = -86.222014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72178815, states[0] = -56.799878, states[40]= 0.000037
Saving checkpoint... 
Iteration: 78050244, states[0] = 27.147743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84186830, states[0] = -68.476865, states[40]= 0.000008
Saving checkpoint... 
Iteration: 89732686, states[0] = -86.412827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96282169, states[0] = -86.686249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101920492, states[0] = -86.957575, states[40]= 0.000002
Saving checkpoint... 
Iteration: 108109989, states[0] = 0.485774, states[40]= 0.000090
Saving checkpoint... 
Iteration: 114940600, states[0] = -86.975344, states[40]= 0.000002
Saving checkpoint... 
Iteration: 121449770, states[0] = -86.982061, states[40]= 0.000002
Saving checkpoint... 
Iteration: 128270456, states[0] = -86.644433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134158328, states[0] = -38.670369, states[40]= 0.000301
Saving checkpoint... 
Iteration: 140270118, states[0] = -86.644127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147470516, states[0] = -86.995115, states[40]= 0.000002
Saving checkpoint... 
Iteration: 154183632, states[0] = -66.902543, states[40]= 0.000010
Saving checkpoint... 
Iteration: 160425830, states[0] = -86.969259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 167675858, states[0] = -57.095271, states[40]= 0.000039
Saving checkpoint... 
Iteration: 173876259, states[0] = -86.919834, states[40]= 0.000002
Saving checkpoint... 
Iteration: 180659435, states[0] = -40.067035, states[40]= 0.000269
Saving checkpoint... 
Iteration: 186874276, states[0] = -86.916992, states[40]= 0.000002
Saving checkpoint... 
Iteration: 193320090, states[0] = -86.816571, states[40]= 0.000002
Saving checkpoint... 
Iteration: 200052810, states[0] = 25.982650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206785298, states[0] = -86.707911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213455995, states[0] = -86.987214, states[40]= 0.000002
Saving checkpoint... 
Iteration: 219730569, states[0] = -86.409692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225733980, states[0] = -86.434191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232772854, states[0] = -86.655413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 239225532, states[0] = -86.370376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246133270, states[0] = -17.964963, states[40]= 0.000187
Saving checkpoint... 
Iteration: 251857799, states[0] = -86.890123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 257631312, states[0] = -16.295847, states[40]= 0.000172
Saving checkpoint... 
Iteration: 263824968, states[0] = -86.825232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 269542958, states[0] = 28.904679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274887217, states[0] = -86.929064, states[40]= 0.000002
Saving checkpoint... 
Iteration: 280690189, states[0] = -77.509911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 286634513, states[0] = -19.016659, states[40]= 0.000203
Saving checkpoint... 
Iteration: 292321821, states[0] = -86.816115, states[40]= 0.000002
Saving checkpoint... 
Iteration: 298324253, states[0] = -86.821664, states[40]= 0.000002
Saving checkpoint... 
Iteration: 304818925, states[0] = -86.808201, states[40]= 0.000002
Saving checkpoint... 
Iteration: 310453800, states[0] = -86.981059, states[40]= 0.000002
Saving checkpoint... 
Iteration: 317036372, states[0] = 30.411762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323424768, states[0] = -86.961626, states[40]= 0.000002
Saving checkpoint... 
Iteration: 329694232, states[0] = -82.596901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336389958, states[0] = -86.928770, states[40]= 0.000002
Saving checkpoint... 
Iteration: 342887026, states[0] = -86.925081, states[40]= 0.000002
Saving checkpoint... 
Iteration: 349486715, states[0] = -86.993840, states[40]= 0.000002
Saving checkpoint... 
Iteration: 355932390, states[0] = -86.965327, states[40]= 0.000002
Saving checkpoint... 
Iteration: 362497284, states[0] = -86.996826, states[40]= 0.000002
Saving checkpoint... 
Iteration: 374976805, states[0] = -86.988496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 402591513, states[0] = 9.882592, states[40]= 0.000018
Saving checkpoint... 
Iteration: 429843054, states[0] = -86.854387, states[40]= 0.000002
Saving checkpoint... 
Iteration: 454555732, states[0] = 24.987659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482077767, states[0] = 16.234880, states[40]= 0.000004
Saving checkpoint... 
Iteration: 507024872, states[0] = 31.760399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534801644, states[0] = -86.746449, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562830468, states[0] = -86.821014, states[40]= 0.000002
Saving checkpoint... 
Iteration: 592484784, states[0] = -86.979544, states[40]= 0.000002
Saving checkpoint... 
Iteration: 618801976, states[0] = -86.742742, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2_2_r298274821_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-BASE_MID-conf_2_2_r298274821_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032321
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 618801976
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.742742 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 642642320, states[0] = -25.311959, states[40]= 0.000389
Saving checkpoint... 
Iteration: 675404755, states[0] = -86.924991, states[40]= 0.000002
Saving checkpoint... 
Iteration: 711176939, states[0] = -58.497947, states[40]= 0.000032
Saving checkpoint... 
Iteration: 742757122, states[0] = -86.549151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768565670, states[0] = 21.296214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800403147, states[0] = -86.916463, states[40]= 0.000002
Saving checkpoint... 
Iteration: 832761239, states[0] = -86.565743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 863179142, states[0] = -61.147917, states[40]= 0.000022
Saving checkpoint... 
Iteration: 898740902, states[0] = -86.443083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913452309, states[0] = -86.946579, states[40]= 0.000002
Saving checkpoint... 
Iteration: 920670444, states[0] = -51.216887, states[40]= 0.000081
Saving checkpoint... 
Iteration: 928648873, states[0] = -30.644200, states[40]= 0.000459
Saving checkpoint... 
Iteration: 936133867, states[0] = -18.421957, states[40]= 0.000192
Saving checkpoint... 
Iteration: 943362223, states[0] = -86.858377, states[40]= 0.000002
Saving checkpoint... 
Iteration: 950346182, states[0] = -86.831002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 958398762, states[0] = -86.903319, states[40]= 0.000002
Saving checkpoint... 
Iteration: 966145210, states[0] = -27.609880, states[40]= 0.000442
Saving checkpoint... 
Iteration: 973700846, states[0] = -85.625123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981181474, states[0] = -64.143147, states[40]= 0.000015
Saving checkpoint... 
Iteration: 988354726, states[0] = -86.843853, states[40]= 0.000002
Saving checkpoint... 
Iteration: 995504112, states[0] = 18.317220, states[40]= -0.000054
Saving checkpoint... 
Iteration: 1002493095, states[0] = -86.959741, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1008859275, states[0] = -86.850094, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1015894362, states[0] = -86.895519, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1023135379, states[0] = -19.677975, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1029644921, states[0] = -27.369540, states[40]= 0.000438
Saving checkpoint... 
Iteration: 1036517640, states[0] = 31.179649, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1042768121, states[0] = -86.587708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049989938, states[0] = -86.955987, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056625272, states[0] = -11.028908, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1063019715, states[0] = 31.526119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070478186, states[0] = -86.950309, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1077474266, states[0] = -86.948255, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1084723279, states[0] = -86.303570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092325102, states[0] = -86.778912, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1098782073, states[0] = -86.645208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106253841, states[0] = -86.510169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112915207, states[0] = -86.909879, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1116717438, states[0] = -86.251914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120255974, states[0] = -86.521246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125306169, states[0] = -86.726820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129398811, states[0] = -86.893790, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1137204922, states[0] = -86.013172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142693155, states[0] = -81.304550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149723103, states[0] = -86.298348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156186172, states[0] = -70.930366, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1163438615, states[0] = -86.924431, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1171013015, states[0] = 29.625873, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1177997958, states[0] = -86.951630, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185196333, states[0] = -84.036735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191529657, states[0] = 31.463608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199247844, states[0] = -86.469727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205018642, states[0] = 31.372290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212146612, states[0] = -28.734725, states[40]= 0.000455
Saving checkpoint... 
Iteration: 1220072857, states[0] = 18.369656, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1253257503, states[0] = -86.521959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277812751, states[0] = -86.737003, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1309030074, states[0] = 31.420390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344000704, states[0] = 34.892702, states[40]= 0.481237
Saving checkpoint... 
Iteration: 1362190532, states[0] = -77.741074, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1369727785, states[0] = -86.322520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374630529, states[0] = -15.531798, states[40]= 0.000166
Saving checkpoint... 
Iteration: 1381972963, states[0] = -86.930735, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1388339172, states[0] = -86.792921, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1395138070, states[0] = -21.847711, states[40]= 0.000270
Saving checkpoint... 
Iteration: 1401671309, states[0] = -52.080695, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1408951975, states[0] = -86.918797, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1416519338, states[0] = 31.483874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424614116, states[0] = -2.489638, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1430704021, states[0] = -85.939418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436410059, states[0] = -86.887350, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1443683113, states[0] = -66.307518, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1449614382, states[0] = -2.665040, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1456387184, states[0] = -86.862934, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1463406090, states[0] = -86.882211, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1470648994, states[0] = -30.696500, states[40]= 0.000455
Saving checkpoint... 
Iteration: 1477012913, states[0] = 29.581772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484867646, states[0] = -86.836065, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1490783623, states[0] = -86.629076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1498154784, states[0] = -35.743149, states[40]= 0.000369
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.810257
 - CaMKt in component CaMK (millimolar): 0.025123
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.057701
 - nass in component intracellular_ions (millimolar): 8.057855
 - ki in component intracellular_ions (millimolar): 143.332741
 - kss in component intracellular_ions (millimolar): 143.332702
 - cansr in component intracellular_ions (millimolar): 2.052323
 - cajsr in component intracellular_ions (millimolar): 1.987507
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008176
 - hf in component INa (dimensionless): 0.659910
 - hs in component INa (dimensionless): 0.659879
 - j in component INa (dimensionless): 0.659702
 - hsp in component INa (dimensionless): 0.411860
 - jp in component INa (dimensionless): 0.659575
 - mL in component INaL (dimensionless): 0.000231
 - hL in component INaL (dimensionless): 0.456170
 - hLp in component INaL (dimensionless): 0.222341
 - a in component Ito (dimensionless): 0.001076
 - iF in component Ito (dimensionless): 0.999463
 - iS in component Ito (dimensionless): 0.534561
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999463
 - iSp in component Ito (dimensionless): 0.578190
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877260
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999617
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003852
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.508449
 - xs1 in component IKs (dimensionless): 0.333482
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997029
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
08:01:53 (871): called boinc_finish(0)

</stderr_txt>
]]>


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