𝕏

Task 55905178

Name HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2
Workunit 26287076
Created 3 Jul 2024, 10:46:28 UTC
Sent 3 Jul 2024, 13:33:59 UTC
Report deadline 6 Jul 2024, 23:09:59 UTC
Received 3 Jul 2024, 16:20:41 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234498
Run time 2 hours 20 min 15 sec
CPU time 2 hours 10 min 53 sec
Validate state Valid
Credit 57.84
Device peak FLOPS 2.67 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.13 MB
Peak swap size 5.29 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.14.3</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15883508, states[0] = -95.205307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32263486, states[0] = -95.110389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48519135, states[0] = 22.311751, states[40]= 0.010770
Saving checkpoint... 
Iteration: 64421256, states[0] = -95.172363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80210946, states[0] = -95.015198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95569980, states[0] = 3.986425, states[40]= 0.004694
Saving checkpoint... 
Iteration: 111348728, states[0] = -95.140349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127811669, states[0] = -95.119510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143929780, states[0] = -95.163668, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 143929780
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.163668 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 160126964, states[0] = -42.172192, states[40]= 0.000098
Saving checkpoint... 
Iteration: 176218569, states[0] = -95.020639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193162364, states[0] = -90.278880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209266654, states[0] = -95.081797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225519034, states[0] = 22.549339, states[40]= 0.010976
Saving checkpoint... 
Iteration: 241605341, states[0] = -21.698717, states[40]= 0.000889
Saving checkpoint... 
Iteration: 257584723, states[0] = -4.138369, states[40]= 0.003574
Saving checkpoint... 
Iteration: 273935271, states[0] = -95.163544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290366066, states[0] = -95.144297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306542807, states[0] = 15.269274, states[40]= 0.005274
Saving checkpoint... 
Iteration: 322515776, states[0] = 23.206296, states[40]= 0.016573
Saving checkpoint... 
Iteration: 338886509, states[0] = -95.151253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355140822, states[0] = -57.045770, states[40]= 0.000009
Saving checkpoint... 
Iteration: 371201878, states[0] = -94.991310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387236989, states[0] = -95.047099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403848806, states[0] = -95.137166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420805117, states[0] = -95.113142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437345738, states[0] = -95.135769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454312938, states[0] = -95.118202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470084166, states[0] = -3.759135, states[40]= 0.003648
Saving checkpoint... 
Iteration: 487302175, states[0] = -95.111087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503456178, states[0] = -95.167170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519605552, states[0] = -21.887167, states[40]= 0.000879
Saving checkpoint... 
Iteration: 535668073, states[0] = -94.151950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552013341, states[0] = 23.686169, states[40]= 0.025368
Saving checkpoint... 
Iteration: 568020751, states[0] = 22.172669, states[40]= 0.009427
Saving checkpoint... 
Iteration: 584190573, states[0] = -94.969435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600791292, states[0] = -95.103032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616647090, states[0] = -64.746541, states[40]= 0.000002
Saving checkpoint... 
Iteration: 633615781, states[0] = -31.347585, states[40]= 0.000424
Saving checkpoint... 
Iteration: 649722567, states[0] = -95.026150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666105043, states[0] = -21.418471, states[40]= 0.000903
Saving checkpoint... 
Iteration: 682669716, states[0] = -94.489321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698549643, states[0] = 12.683033, states[40]= 0.005097
Saving checkpoint... 
Iteration: 715240725, states[0] = -95.051823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731796546, states[0] = -95.106919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747859610, states[0] = -95.141504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763795190, states[0] = -95.105896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779851192, states[0] = -95.137986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795919460, states[0] = -95.159818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812107170, states[0] = -23.376427, states[40]= 0.000808
Saving checkpoint... 
Iteration: 828040745, states[0] = 16.025976, states[40]= 0.005360
Saving checkpoint... 
Iteration: 844279870, states[0] = -95.093514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861437419, states[0] = -95.163589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877942038, states[0] = -95.164462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894347772, states[0] = -95.136414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910524859, states[0] = 21.156239, states[40]= 0.007417
Saving checkpoint... 
Iteration: 927236698, states[0] = -95.046384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944105069, states[0] = -21.442259, states[40]= 0.000902
Saving checkpoint... 
Iteration: 960545033, states[0] = 14.439196, states[40]= 0.005202
Saving checkpoint... 
Iteration: 976612840, states[0] = -28.610839, states[40]= 0.000559
Saving checkpoint... 
Iteration: 992605620, states[0] = -21.949507, states[40]= 0.000876
Saving checkpoint... 
Iteration: 1009146664, states[0] = -64.184808, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1025394866, states[0] = -95.153341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041576585, states[0] = 0.798632, states[40]= 0.004372
Saving checkpoint... 
Iteration: 1057572396, states[0] = 2.966203, states[40]= 0.004602
Saving checkpoint... 
Iteration: 1073565551, states[0] = 6.165892, states[40]= 0.004831


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630011100300215_ORdGradInc_k_25-Pueyo_APDR-conf_228_2_r1032444331_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 99.338384
     * GNaL_b in INaL: 0.005888
     * Gto_b in Ito: 0.075501
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030155
     * GKs_b in IKs: 0.001966
     * GK1_b in IK1: 0.181535
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.250261
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027439
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1073565551
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 6.165892 (After loading)
 - states[40]: 0.004831 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1090061790, states[0] = 7.796070, states[40]= 0.004911
Saving checkpoint... 
Iteration: 1106096158, states[0] = -13.286943, states[40]= 0.001725
Saving checkpoint... 
Iteration: 1123024136, states[0] = 21.346619, states[40]= 0.007663
Saving checkpoint... 
Iteration: 1139001464, states[0] = 48.119569, states[40]= 0.058894
Saving checkpoint... 
Iteration: 1155053664, states[0] = 11.113951, states[40]= 0.005033
Saving checkpoint... 
Iteration: 1171550871, states[0] = 12.207903, states[40]= 0.005075
Saving checkpoint... 
Iteration: 1187559438, states[0] = 8.781298, states[40]= 0.004950
Saving checkpoint... 
Iteration: 1203086716, states[0] = -5.538554, states[40]= 0.003287
Saving checkpoint... 
Iteration: 1220316584, states[0] = -95.119985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237241243, states[0] = -95.052180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253250451, states[0] = -95.063480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269315802, states[0] = -95.119482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284081267, states[0] = -1.898631, states[40]= 0.003982
Saving checkpoint... 
Iteration: 1301091420, states[0] = -9.193842, states[40]= 0.002502
Saving checkpoint... 
Iteration: 1317708451, states[0] = -95.002521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333653202, states[0] = -73.880388, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350464044, states[0] = -95.167917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367818586, states[0] = -95.121093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384482809, states[0] = -95.170540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401709337, states[0] = -95.004013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417825473, states[0] = -95.125002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434243426, states[0] = -95.054839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451555453, states[0] = 10.402558, states[40]= 0.005008
Saving checkpoint... 
Iteration: 1467811388, states[0] = -95.116623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484286201, states[0] = -95.098461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501255432, states[0] = 6.977585, states[40]= 0.005370
Saving checkpoint... 
Iteration: 1517210046, states[0] = -43.196967, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1532680194, states[0] = -95.378196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549228498, states[0] = 18.888826, states[40]= 0.007583
Saving checkpoint... 
Iteration: 1565870855, states[0] = -95.240778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582013405, states[0] = -49.579540, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1598264056, states[0] = -95.228645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615042106, states[0] = -93.210155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631280229, states[0] = -95.268548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647117400, states[0] = -54.860118, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1662870787, states[0] = -95.391893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678966244, states[0] = -95.237003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695280055, states[0] = -95.399089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711072754, states[0] = -95.252829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727952268, states[0] = -95.375924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745079641, states[0] = -95.398856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761777709, states[0] = -95.263985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778186914, states[0] = -20.795716, states[40]= 0.000998
Saving checkpoint... 
Iteration: 1794043582, states[0] = 11.779045, states[40]= 0.006012
Saving checkpoint... 
Iteration: 1810004682, states[0] = 30.574355, states[40]= 0.158616
Saving checkpoint... 
Iteration: 1826112604, states[0] = -30.444850, states[40]= 0.000468
Saving checkpoint... 
Iteration: 1842381470, states[0] = -95.165016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858344937, states[0] = -95.144854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874177085, states[0] = -94.922536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891344691, states[0] = -95.138389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907794997, states[0] = -95.107547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923817087, states[0] = -95.121412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940474566, states[0] = -95.170036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956805088, states[0] = -95.112780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972804734, states[0] = -95.112302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988898020, states[0] = -95.153860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004865105, states[0] = -95.143001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020407886, states[0] = -95.156332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036538526, states[0] = 16.822957, states[40]= 0.005475
Saving checkpoint... 
Iteration: 2052882862, states[0] = -95.149063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068876205, states[0] = -95.146830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084775066, states[0] = -95.088460, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.048000
 - CaMKt in component CaMK (millimolar): 0.006948
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.612287
 - nass in component intracellular_ions (millimolar): 6.612347
 - ki in component intracellular_ions (millimolar): 145.366431
 - kss in component intracellular_ions (millimolar): 145.366412
 - cansr in component intracellular_ions (millimolar): 1.308660
 - cajsr in component intracellular_ions (millimolar): 1.270423
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003566
 - hf in component INa (dimensionless): 0.882514
 - hs in component INa (dimensionless): 0.882509
 - j in component INa (dimensionless): 0.882482
 - hsp in component INa (dimensionless): 0.730584
 - jp in component INa (dimensionless): 0.882465
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713257
 - hLp in component INaL (dimensionless): 0.454923
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.619032
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.693403
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931120
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999871
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001593
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337855
 - xs1 in component IKs (dimensionless): 0.248424
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997298
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:15:51 (47364): called boinc_finish(0)

</stderr_txt>
]]>


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